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Encyclopedia results for sickle cell disease

sickle cell disease





Encyclopedia results for sickle cell disease

  1. Sickle-cell disease

    About the disease itself the genetic transmission of sickle cell disease and its carrier state sickle cell trait Use British English date November 2010 Infobox disease Name Sickle cell disease Image sicklecells.jpg ... Cell anemia MeshNumber C15.378.071.141.150.150 GeneReviewsID sickle GeneReviewsName Sickle cell disease Sickle cell disease SCD , or sickle cell anaemia or anemia SCA or drepanocytosis , is an autosome ... Mortality in sickle cell disease. Life expectancy and risk factors for early death journal N. Engl ... cgi content full 330 23 1639 doi 10.1056 NEJM199406093302303 issn 0028 4793 ref Sickle cell disease ... anaemia is the name of a specific form of sickle cell disease in which there is homozygote homozygosity ..., rarer forms of sickle cell disease include sickle haemoglobin C disease HbSC , sickle beta plus ... of sickle cell disease are compound heterozygous states in which the person has only one copy of the mutation ... polymorphism . Signs and symptoms Sickle cell disease may lead to various acute and chronic ... disease. Sickle cell disease results in anaemia and crisis that could be of many types including the vaso .... Approximately 10 15 of children with sickle cell disease suffer strokes, with silent strokes predominating ... Kenny MW, George AJ, Stuart J title Platelet hyperactivity in sickle cell disease a consequence ... of sickle cell disease journal American Journal of Surgery volume 201 issue 4 pages 468 74 year 2011 ... bacterial bone infection the most common cause of osteomyelitis in sickle cell disease is Salmonella .... ref cite journal author Almeida A, Roberts I title Bone involvement in sickle cell disease journal .... Addiction to opiates occurs no more commonly among individuals with sickle cell disease than among ... author Elagouz M, Jyothi S, Gupta B, Sivaprasad S title Sickle cell disease and the eye old and new ... of pain in adults with sickle cell disease journal Ann. Intern. Med. volume 148 issue 2 pages ... Pulmonary hypertension as a risk factor for death in patients with sickle cell disease journal N. Engl ...   more details



  1. Sickle Cell Anemia, a Molecular Disease

    Sickle Cell Anemia, a Molecular Disease is a 1949 scientific paper by Linus Pauling , Harvey A. Itano , Seymour J. Singer and Ibert C. Wells that established sickle cell anemia as a genetic disease in which ... basis for the disease, consistent with the simultaneous genealogical study by James V. Neel those with sickle cell anemia are homozygous for the disease gene, while heterozygous individuals exhibit the usually asymptomatic condition of sickle cell trait. ref name SCAAMD Cite journal volume ..., Ibert C. Wells title Sickle Cell Anemia, a Molecular Disease journal Science date 1949 11 01 bibcode ... as a physician the task of finding differences in hemoglobin that might explain sickle cell disease ... on the disease. Itano also found that the globin portion of sickle cell hemoglobin had a barely ... cell trait Malaria Sickle cell disease confers resistance to malaria and so the gene had both ... papers 1949p.15.html Sickle Cell Anemia, a Molecular Disease &mdash reproduction of the paper History ... in electrophoretic mobility between hemoglobin from healthy individuals and those with sickle cell anemia, with those with sickle cell trait having a mixture of the two types. The paper suggests that the difference ... last Strasser first Bruno J. title Perspectives Molecular Medicine Sickle Cell Anemia, a Molecular ..., Pauling s researchers were able to estimate that molecules of sickle cell hemoglobin had about ... that blood from those with sickle cell trait was a mixture of 60 percent normal hemoglobin and 40 percent sickle cell hemoglobin. ref name SCAAMD Near the end of the project, they learned of parallel ... of the amino acid content of normal and sickle cell hemoglobins showed that they had several differences ... cell trait and other molecular disease genes, to reduce the number of children born with genetic ... It s in the Blood A Documentary History of Linus Pauling, Hemoglobin and Sickle Cell Anemia &mdash ... of a molecular disease , and is considered a major impetus to the development of molecular medicine ...   more details



  1. Sickle cell nephropathy

    Orphan date March 2009 Sickle cell nephropathy is a type of nephropathy associated with sickle cell disease , it causes renal complications as a result of sickling of red blood cells in the microvasculature . The hypertonic and relatively Hypoxia medical hypoxic environment of the renal medulla , coupled with the slow blood flow in the vasa recta , favors sickling of red blood cells, with resultant local infarction papillary necrosis . Functional renal tubules tubule defects in patients with sickle cell disease are likely the result of partial ischemic injury to the renal tubules . Also the sickle cell disease in young patients is characterized by renal hyperperfusion , glomerular hypertrophy , and hyperfiltration . Many of these individuals eventually develop a glomerulopathy leading to glomerular proteinuria present in as many as 30 and, in some, the nephrotic syndrome . Co inheritance of Deletion genetics microdeletions in the globin gene thalassemia appear to protect against the development of nephropathy and are associated with lower mean arterial pressure and less proteinuria . Mild azotemia and hyperuricemia can also develop. Advanced renal failure and uremia occur in 10 of cases. Pathologic examination reveals the typical lesion of hyperfiltration nephropathy namely, focal ... described above, renal complications of sickle cell disease include cortical infarcts ... gross hematuria occurs with a higher frequency in sickle trait than in sickle cell disease ... infarcts , demonstrable radiographically in 50 of patients with sickle trait, lead to an increased ... with sickle trait. Other tubule defects involve potassium and hydrogen ion excretion , occasionally ... of sickle nephropathy is not separate from that of overall patient management. In addition, however .... Three year Medical grafting graft and patient survival in renal transplant recipients with sickle nephropathy is diminished as compared to those with other causes of end stage renal disease ...   more details



  1. Sickle cell trait

    About the genetic transmission of sickle cell diseases the disease itself sickle cell disease Infobox disease Name Sickle cell trait Image Caption DiseasesDB ICD10 ICD10 D 57 3 d 55 ICD9 ICD9 282.5 ICDO ... beta gene is heterozygous , but does not display the severe symptoms of sickle cell disease ... for the sickle cell allele produce both normal and abnormal hemoglobin the two alleles are co dominant . Sickle cell disease is a blood disorder in which the body produces an abnormal type of the oxygen carrying substance hemoglobin in the red blood cells . Sickling and sickle cell disease also confer ... hemoglobin is called hemoglobin A, but people with sickle cell disease have only hemoglobin S, which ... discovered the earliest proof of Sickle cell disease while looking for the virus of the 1918 flu ... Betty Pace title Renaissance of Sickle Cell Disease Research in the Genome Era url http books.google.com ... hemoglobin A , genotype AA . A person with sickle cell trait inherits one normal gene and one abnormal gene encoding hemoglobin S hemoglobin genotype AS . Prevalence Sickle cell trait prevalence is highest ... needed date September 2008 Symptoms Sickle cell trait is a hemoglobin genotype AS is generally regarded as a benign condition. ref name pmid16286558 cite journal author Roach ES title Sickle cell ...?view long&pmid 16286558 ref However, individuals with sickle cell trait may have rare complications ... a sickle cell crisis that contributed to his death even though he had one copy of the gene. ref http www.wired.com wiredscience 2010 11 from a 1918 autopsy a first glimpse of sickle cell E2 80 94 C2 A0and a warning From 1918 Autopsy, A First Glimpse of Sickle Cell and a Warning www.wired.com ref There have been calls to reclassify sickle cell trait as a disease state, based on its malignant clinical presentations. ref name pmid16198915 cite journal author Ajayi AA title Should the sickle cell ... Dessources MD, Morrison E, Hue O title Physiological responses of sickle cell trait carriers during ...   more details



  1. File:Sickle cell hemoglobin shortened.png

    Summary A shortened version of the figure http commons.wikimedia.org wiki Image Sickle cell hemoglobin.png Licensing PD USGov ...   more details



  1. I-cell disease

    Infobox disease Name I cell disease Image Mannose 6 phosphate.svg Caption Mannose 6 phosphate M6P . I cell disease involves a failure to add M6P to proteins. DiseasesDB 29175 ICD10 ICD10 E 77 0 e 70 ICD9 ICD9 272.7 ICDO OMIM 252500 MedlinePlus eMedicineSubj ped eMedicineTopic 1150 MeshID D009081 Inclusion cell I cell disease , also referred to as mucolipidosis II ML II , ref DorlandsDict five 000067904 mucolipidosis II ref ref name pmid18190596 cite journal author Plante M, Claveau S, Lepage P, et al. title Mucolipidosis II a single causal mutation in the N acetylglucosamine 1 phosphotransferase gene GNPTAB in a French Canadian founder population journal Clin. Genet. volume 73 issue 3 pages 236 44 year 2008 month March pmid 18190596 doi 10.1111 j.1399 0004.2007.00954.x url http www.blackwell synergy.com openurl?genre article&sid nlm pubmed&issn 0009 9163&date 2008&volume 73&issue 3&spage 236 ref is part of the lysosomal storage disease family and results from a defective phosphotransferase ... tract infections. Pathophysiology I cell disease is an autosomal recessive disorder caused ... Treatment There is no cure yet for I Cell disease Mucolipidosis II disease. Treatment is limited to controlling ..., particularly iron and vitamin B12, are often recommended for individuals with I Cell disease. Physical ... deterioration that occurs with I Cell disease. http www.bmt.umn.edu disease Metabolic home.html ... detail sheet available here RareDiseases 6749 I cell disease http www.ncbi.nlm.nih.gov bookshelf br.fcgi ... are constitutively secreted outside of the cell instead. These substances or waste products ... a diagnosis of the disease. Presentation ML II is a particularly severe form of ML that resembles ... phosphate on glycoprotein N linked glycoproteins in the Golgi apparatus within the cell. Without mannose ... degradation in patients with the disease hence the name of the disorder . ref name lippincott s 3rd ... Foundation For Lysosomal Disease Research Glycoproteinoses Posttranslational modification disorders ...   more details



  1. Sickle

    For the United States Civil War general Daniel Sickles Image Sickle hanging from a rusty nail at Ardeshir s farm.jpg thumb A sickle on a Polish farm A sickle is a hand held agricultural tool with a curved ... held in a bunch, the sickle action is towards the user left to right for a right handed user , but when used free the sickle is usually swung the opposite way. Different types may be referred to as a grasshook ... hook . Image SickleUser wb.png thumb left upright 250px Using a sickle The blade of a sickle is often ... or more rarely left handed. Sickles used for reaping are usually serrated. The sickle was largely ... to be in use in many parts of the world. The most noticeable difference between a sickle and a scythe is the length of the handle a sickle is a one handed tool with a short handle, used while bending ... shaft, and a much longer blade. Image Sickle and scythe labels.jpg thumb right upright 250px Sickle ... a characteristic sickle gloss , or wear pattern. It was a critical tool that was used to facilitate ... 30 issue 1 pages 88 103 year 1989 ref History Americas The sickle has been discovered in Southwest ... made from other material such as the Caddo Sickle, which was made from a deer mandible. Scripture ... 10.2307 276785 last Heizer first Robert F. title The Sickle in Aboriginal Western North America url ... The sickle in general provided the convenience of cutting the grass as well as gathering in one step. In South America, the sickle was used as a tool to harvest rice. Rice clusters were harvested using ... thumb left upright 250px Harvesting Sickle from Iraq dated to be around 3000 B.C. Fertile Crescent The development of the sickle in Mesopotamia can be traced back to times that pre date the Neolithic Era . Large quantities of sickle blades have been excavated in sites surrounding Palestine that have ... on Flint Sickle Blades as an Indication of Plant Cultivation Preliminary Results journal World Archaeology ... unearthed various forms of early sickle blades. The artifacts recovered ranged from 1 to 2  cm ...   more details



  1. Lethal arthrogryposis with anterior horn cell disease

    Lethal arthrogryposis with anterior horn cell disease LAAHD is an autosomal recessive genetic disorder characterized by reduced mobility of the foetus and early death. Characteristics LAAHD resembles Lethal congenital contracture syndrome LCCS1 disease but the phenotype is milder, with survival beyond 32nd gestational week. However, the foetuses are often stillborn or survive only few minutes. The movements of the foetus during pregnancy are scanty and stiff, often only in upper limbs. The malpositions are distal . The inwards spiral and especially the elbow contractures are less severe than in LCCS1 disease. Some patients have intrauterine long bone fractures. Skeletal muscles are affected and show neurogenic atrophy . The size and shape of spinal cord at different levels are normal but anterior horn motoneurons are diminished in number and degenerated. ref name vuopala cite journal author Vuopala K, Ignatius J, Herva R title Lethal arthrogryposis with anterior horn cell disease journal Hum Pathol volume 26 issue 1 pages 12 19 year 1995 month pmid 7821908 doi 10.1016 0046 8177 95 90109 4 url issn ref Population genetics LAAHD is one of approximately 40 Finnish heritage disease Finnish heritage diseases . Families affected by these diseases come from different parts of Finland , and birthplaces of the ancestors of affected individuals do not show geographic clustering. Molecular genetics LAAHD disease results from compound heterozygosity of GLE1FinMajor and a missense point mutation in exon 13 6 cases in 3 families or a missense mutation in exon 16 seven cases in 3 families . One of the latter cases survived 12 weeks, mostly under artificial respiration. ref name nousiainen cite journal author Nousiainen HO, Kestil M, Pakkasj rvi N, Honkala H, Kuure S, Tallila J, Vuopala K, Ignatius J, Herva R, Peltonen L title Mutations in mRNA export mediator gene GLE1 result in a fetal motoneuron disease journal Nature Genetics volume 40 issue 2 pages 155 157 year 2008 month February ...   more details



  1. Sickle Ridge

    Orphan date February 2009 Sickle Ridge coord 78 1 S 162 10 E is a ridge in East Antarctica . The ridge has a distinctive sickle shape. usgs gazetteer Category Ridges of Antarctica EAntarctica geo stub ...   more details



  1. Sickle-gloss

    Sickle gloss , or sickle gloss , is a silica residue found on blade s suggesting that they have been used to cut the silica rich stems of cereal s and forming an indirect proof for incipient agriculture . The first documented appearance of sickle gloss is found on flint Knapping knapped blades in the Natufian culture 12,500 to 9500 BC in the Middle East , primarily in Palestine . References Refbegin Bar Yosef, Ofer 1998 , The Natufian Culture in the Levant, Threshold to the Origins of Agriculture , Evolutionary Anthropology 6 5 159 177, doi 10.1002 SICI 1520 6505 1998 6 5 159 AID EVAN4 3.0.CO 2 7, http www.columbia.edu itc anthropology v1007 baryo.pdf Refend Category Methods and principles in archaeology Archaeology stub ...   more details



  1. Koller's sickle

    In bird avian gastrulation , Koller s sickle is a local thickening of cells that acts as a margin separating sheets of cells from posterior margin of avian blastoderm s from hypoblast s as they migrate anteriorly to push primary hypoblast cells anteriorly to form a secondary hypoblast known as the endoblast . The Posterior Marginal Zone PMZ of Koller s sickle can induce a primitive streak and Hensen s node , acting as an organizer. ref Bachvarova RF, Skromne I, Stern CD. Induction of primitive streak and Hensen s node by the posterior marginal zone in the early chick embryo. Development. 1998 Sep 125 17 3521 34. ref References references DEFAULTSORT Koller s Sickle Category Gastrulation developmental biology stub ...   more details



  1. Sickle Mountain

    Orphan date February 2009 Sickle Mountain coord 68 53 S 66 47 W is a mountain , 1,250 m, standing on the south side of Clarke Glacier and 14 miles 22 km east of Cape Berteaux , on the west coast of Graham Land . So named by Finn Ronne of the East Base of the United States Antarctic Service USAS , 1939 41, because its peculiar shape was suggestive of that of a sickle. usgs gazetteer Category Mountains of Antarctica WAntarctica geo stub ...   more details



  1. Sickle Barb

    orphan date February 2010 Taxobox name Sickle Barb status regnum Animalia phylum Chordata classis Actinopterygii ordo Cypriniformes familia Cyprinidae genus Barbus species B. haasianus binomial Barbus haasianus binomial authority David, 1936 Sickle Barb Barbus haasianus is a species of ray finned fish in the genus Barbus . Footnotes fishbase Barbus haasianus Category Barbus Barbus stub ca Barbus haasianus es Barbus haasianus ...   more details



  1. Sickle-hocked

    Unreferenced date September 2007 Sickle hocked is the technical term used to describe a specific type of incorrect leg structure in animals. The back leg joints of an animal, usually a horse or other equine mammal, are set with too much angle , resulting in the Hock zoology hock also being excessively angled. This can result in uneven hoof wear, which is incredibly painful for the affected horse. If the leg joints are not set properly, there is a high chance that the back joints are also set incorrectly, resulting in a poorly equine conformation conformed horse. Horses with sickle hocks are at an increased risk of developing thoroughpin, curb horse curb and bog spavin bog or bone spavin s. Very severe cases of sickle hocks can result in permanent Lameness equine lameness and may require euthanasia euthanization to prevent further pain. However, many horses with sickle hock are not affected to this degree, and may live a life with uneven wearing hooves. farrier Corrective shoeing can help the horse s balance and strength. Horses with sickle hocks should be monitored closely for signs of lameness, and if possible a veterinarian should be consulted before extensive exercise. http www.horsekeeping.com horse conformation sickle hock.htm In cases of horse breeding breeding , it is generally considered unwise to continue breeding a mare or stallion with sickle hocks, http www.horses arizona.com pages articles legset.html as the trait is often passed to the offspring. Other animals who have this condition include, but are not limited to, cattle , sheep , and other types of livestock . See also Cow hocked Knock kneed Post legged Bow leg Category Livestock Category Horse anatomy Category Equine injury and lameness agri stub ...   more details



  1. Sickle tail

    Orphan date November 2006 The sickle tail is the single phenotypic characteristic that seems to separate dogs from wolves ref Cite book author M kl si, d m authorlink coauthors title Dog behaviour, evolution, and cognition date 2007 publisher Oxford University Press location Oxford isbn 9780199295852 page90 ref . Dogs who have tails tend to have an upward curve in the tail, which is called the sickle tail. Wolves tails, on the other hand, hang straight this is called the brush tail similar to that of a fox. References reflist Category Dog anatomy dog stub ...   more details



  1. Hammer and sickle

    Other uses File Hammer and sickle.svg thumb 200px Traditional style Hammer and Sickle File South Asian Communist Banner.svg thumb 200px The South Asian variant of the hammer and sickle. File Hammer and Sickle symbol..png thumb 200px Another South Asian variant of the hammer and sickle. The hammer and sickle ... party , or a Communist state . It features a hammer and a sickle overlapping each other. The two ... is banned in some European countries. Soviet and Russian usage The hammer and sickle was originally ... known hammer and sickle. The hammer and sickle, though in use since 1917 18, was not the official symbol ... of Arms of the Soviet Republics showed the hammer and sickle, which also appeared on the Red Star badge ... of Russian transliteration of lang ru , sickle and hammer is the name of the Moscow Metallurgical ... Current usage Two federal subjects of the post Soviet Russian Federation use the hammer and sickle ..., Aeroflot , continues to use the hammer and sickle in its symbol. The separatist government of Transnistria ... include the hammer and sickle. The flag can also be used without the hammer and sickle in some circumstances .... The Maoist group, Shining Path in Peru uses it as part of its symbol. A hammer and a sickle ... in Kerala , India showing two workers forming the hammer and sickle. Many symbols having similar structures ... by a half cog and a semicircle semicircular sickle blade. A hammer is laid directly over the sickle ..., with a star on the top. Tools represented in other designs include the Ink brush brush , sickle ... a hammer and sickle symbol on which the number 4 is superimposed. The Trotskyist League for the Fifth International merges a hammer with the number 5 , using the number s lower arch to form the sickle ... movement. It is usually used in conjunction with the hammer and sickle, and appears on all .... Similarly, the Communist Party of Israel uses a dove over the hammer and sickle as its symbol. The flag of the Guadeloupe Communist Party Communist Party of Guadeloupe uses a sickle, turned to look like ...   more details



  1. Hammer & Sickle

    Otheruses2 1 Hammer and sickle Infobox VG title Hammer & Sickle image Image Hammer & Sickle.jpg caption European boxart of Hammer & Sickle developer Novik&Co , Nival Interactive publisher CDV Software Entertainment br T time Technology engine Silent Storm engine released vgrelease Russia RU start date 2005 04 29 br vgrelease NA start date 2005 12 05 genre Tactical RPG modes Single player platforms Personal computer PC media Compact Disc CD 3 requirements Microsoft Windows , 1 GHz central processing unit Processor , 256 Megabyte MB Random access memory RAM , 32MB video card input Computer mouse mouse , Computer keyboard keyboard Hammer & Sickle Lang ru 1 is a tactical role playing game ref name gamzone cite web title Nival Interactive Announces Hammer & Sickle publisher GameZone url http pc.gamezone.com news 04 29 05 10 00AM.htm format HTML accessdate 2007 11 26 ref ref name gamecritics cite web title Hammer & Sickle publisher GameCritics.com url http www.gamecritics.com node 1928 format HTML accessdate 2007 11 26 ref for the PC, co developed by the Russia based companies Novik&Co and Nival Interactive ref name gamzone and published by CDV Software Entertainment CDV in 2005. The game is set in the same universe and runs on the same game engine as Silent Storm , an earlier product by the same company. The player takes on the role of a Soviet commando assigned to operate behind British American lines in 1949 post World War II Germany . Germany has recently been divided between Soviet and Western zones, the Cold War has just begun, and the Americans still have a monopoly on the atomic bomb . Features Image Hammer n Sickle game.JPG left thumb Gameplay The game features .... Hammer & Sickle also employs ragdoll physics for bodies according to the precise velocity of an impact ... pc hammer sickle 672687p1.html with the polish of the end product being the most common ... the international Chinese edition of Hammer & Sickle under the name zh p di b o j ngy ng ...   more details



  1. Sickle Nunatak

    Orphan date February 2009 Sickle Nunatak coord 71 32 S 161 57 E is a nunatak at the north side of the entrance to Jupiter Valley , on the east side of the Morozumi Range . So named by members of the New Zealand Geological Survey Antarctic Expedition NZGSAE , 1967 68, because of its shape. usgs gazetteer Category Nunataks of Antarctica EAntarctica geo stub ...   more details



  1. The Sword and the Sickle

    infobox Book See Wikipedia WikiProject Novels or Wikipedia WikiProject Books name The Sword and the Sickle title orig translator image prefer 1st edition image caption author Mulk Raj Anand illustrator cover artist country India language English language English series genre Novel publisher release date 1942 english release date media type Print pages isbn oclc 3850942 preceded by Across the Black Waters followed by The Big Heart book The Big Heart The Sword and the Sickle is a novel by Mulk Raj Anand first published in 1942. Like his other novels, this one also deals with the topic of social and political structures, specifically, the rise of Communism . ref cite news url http www.hindu.com lr 2005 12 04 stories 2005120400090200.htm title Poetics of Protest date December 04, 2005 publisher The Hindu accessdate 2009 09 02 ref The title for the book was given to Anand by George Orwell . ref cite news url http www.telegraph.co.uk news obituaries 1472853 Mulk Raj Anand.html title Mulk Raj Anand publisher The Daily Telegraph accessdate 2009 08 31 location London date 2004 09 29 ref The novel was in keeping with United Kingdom British and United States American writings of the time. ref cite news url http www.financialexpress.com news the end of an era 67601 0 title The end of an era date October 3, 2004 publisher Financial Express accessdate 2009 09 02 ref The book was the final part of the trilogy that included The Village book The Village and Across the Black Waters . ref cite book last George first C. J, title Mulk Raj Anand, his art and concerns a study of his non autobiographical novels publisher Atlantic Publishers date 1994 pages 77 isbn 9788171564453 url http books.google.com books?id M7LSHdlvRtcC&lpg PA51&dq 22Two 20Leaves 20and 20a 20Bud 22 2B 22Mulk 20Raj 20Anand 22&pg PA51 v onepage&q 22Two 20Leaves 20and 20a 20Bud 22 22Mulk 20Raj 20Anand 22&f false accessdate 2009 08 31 ref References reflist Mulk Raj Anand DEFAULTSORT Sword and the Sickle Category Novels by Mulk ...   more details



  1. The Disease

    for an abnormal condition affecting the body of an organism Disease Infobox television episode Title The Disease Image Image ST VOY The Disease.jpg 270px br Harry Kim becomes intimate with Varro scientist Tal Series Star Trek Voyager Season 5 Episode 17 Production 210 Airdate February 24, 1999 Writer Kenneth Biller br Michael Taylor screenwriter Michael Taylor Director David Livingston director David Livingston Guests Musetta Vander as Tal br Charles Rocket as Jippeq Prev Dark Frontier Next Course Oblivion Star Trek Voyager Course Oblivion Episode list List of Star Trek Voyager episodes The Disease is an episode of Star Trek Voyager , the 17th episode of the fifth season. The episode had an average rating of 4.2 5 on the official Star Trek website as of August 23, 2007 . http www.startrek.com startrek view series VOY episode 104851.html Plot Voyager stops to assist a xenophobic species known as the Varro. This species lives on a Generation ship generational ship which has housed them for 400 years. While the crew works on the Varro ship, Voyager is infested with synthetic ship eating parasites that had been released on the Varro ship by dissident Varro. Meanwhile, Harry Kim Star Trek Harry Kim becomes intimate with Varro scientist Tal, and develops a physiological bond with her, one that is standard in the Varro. The physiological connection alters his behavior and sways him from his duties aboard Voyager . It is later revealed that Tal is one of the separatists. There has been a rumour of a minority of Varro that want off the ship. The parasites that Tal helped create were made to separate the individual pods of the Varro ship without destroying the ship itself. Fractures along the hull created by the parasites begin to grow as the Varro ship begins to fall apart. Voyager ... say good bye to his recent love. External links memoryalpha article The Disease The Disease http ... Disease, The Category Star Trek Voyager episodes Category 1999 television episodes StarTrek ...   more details



  1. T cell

    gene can prevent regulatory T cell development, causing the fatal autoimmune disease IPEX syndrome IPEX . Natural killer Natural killer T cell s NKT cells are a special kind of lymphocyte that bridges ... center and a red blood cell left T cells or T lymphocytes belong to a group of white blood cell s known as lymphocytes , and play a central role in cell mediated immunity . They can be distinguished from other lymphocyte types, such as B cell s and natural killer cell s NK cells by the presence of a special receptor on their cell surface called T cell receptor s TCR . The abbreviation T , in T cell , stands for thymus , since this is the principal organ responsible for the T cell s maturation. Several ... T helper cell T sub H sub cells assist other white blood cells in immunologic processes, including maturation of B cell s into plasma cell s and B memory cell s, and activation of cytotoxic T cells ... Cell s APCs . Once activated, they divide rapidly and secrete small proteins called cytokine ... subtypes, including T helper cell T sub H sub 1 , Th2 T sub H sub 2 , Th3 T sub H sub 3 , Th17 ... cite web url http www.jci.org articles view 31720 title APC derived cytokines and T cell polarization in autoimmune inflammation ref Cytotoxic Cytotoxic T cell s T sub C sub cells, or CTLs destroy virally ... is present on the surface of nearly every cell of the body. Through IL 10, adenosine and other ... web url http www.jci.org cgi content full 114 9 1198 title An integrated view of suppressor T cell subsets in immunoregulation ref Memory Memory T cell s are a subset of antigen specific T cells that persist ... sup . Memory T cells typically express the cell surface protein CD45RO. Citation needed date February 2010 Regulatory Regulatory T cell s T sub reg sub cells , formerly known as suppressor T cells , are crucial for the maintenance of immunological tolerance . Their major role is to shut down T cell ... cell killing molecules . They are also able to recognize and eliminate some tumor cells ...   more details



  1. Cell

    wiktionarypar cell Cell s may refer to TOCright Science and technology Cell biology , the functional basic unit of life Cell EDA , a term used in a electronic circuit design schematics Cell geometry , a three dimensional element, part of a higher dimensional object Cell journal Cell journal , a scientific journal Cell microprocessor , a microprocessor architecture developed by Sony, Toshiba, and IBM Cell, the basic unit of Flash memory Principles of operation Flash memory Cell or mobile phone , a phone connected to a cellular network Cell, area of radio coverage in a cellular network Cell, an basic unit of a cellular automaton Cell, an individual production area in cellular manufacturing Cell, a fixed length packet in a cell relay communication network Voltaic cell, a device for producing electricity, including Electrochemical cell , a device for extracting electricity from chemical reactions, often used as part of a battery Photo electric or solar cell Storm cell , an updraft region in a thunderstorm Table cell , the intersection of a row and a column in a table of information Music Cell music , a rhythmic, melodic, motivic, or intervallic group, set, or figure Cell band , a rock band ... The Servant Fiction Cell comics , a Marvel comic book character Cell, a List of Dragon Ball characters Cell character in Dragon Ball media Cell novel Cell novel , a 2006 horror novel by Stephen King Society Prison cell , a room used to hold people in prisons Cell, a unit of a clandestine cell system , a penetration resistant form of a secret or outlawed organization Cell, a group of people in a cell group Religion Cell, a room or hut in which a monk or nun lives. See also The Cell disambiguation Cellular disambiguation CEL disambiguation disambig cy Cell da Celle de Zelle es C lula desambiguaci n eo elo apartigilo fr Cellule gl C lula hom nimos ko it Cell he nl Cel ja no Celle ... ru simple Cell disambiguation sk Bunka rozli ovacia str nka sr sh elija su ...   more details



  1. S cell

    Unreferenced stub auto yes date December 2009 S cells are cells which release secretin , found in the jejunum and duodenum . They are stimulated by a drop in pH to 4 or below in the small intestine s lumen. The released secretin will increase the secretion of HCO sub 3 sub sup sup into the lumen, via the pancreas . S cells are also one of the main producers of cyclosamatin . For more information on the function of S cells, see secretin . Gastrointestinal physiology Human cell types derived primarily from endoderm DEFAULTSORT S Cell Category Human cells Cell biology stub ru S ...   more details



  1. The Cell

    About Infobox film name The Cell image Thecellposter.jpg caption Original film poster director Tarsem ... US language English budget 33 million gross 104,155,843 followed by The Cell 2 The Cell is a 2000 science ... in a prison cell cell in the form of a glass enclosure that is slowly filling with water by means ... had been entrusted by a company to take care of an advanced water pump, which he used to fill the cell ... of the scenes in The Cell are inspired by works of art. A scene in which a horse is split into sections ... . ref name influences cite web url http www.imdb.com title tt0209958 trivia title The Cell 2000 ... reaction to The Cell has been mixed, with the film earning a rating of 45 on Rotten Tomatoes . ref http www.rottentomatoes.com m cell The Cell Movie Reviews, Pictures Rotten Tomatoes ref Roger Ebert .... ref http rogerebert.suntimes.com apps pbcs.dll article?AID 20000818 REVIEWS 8180303 1023 The Cell ... The Cell becomes the first serial killer feature in a long time to take the genre in a new direction ... the horrors that can turn an ordinary child into an inhuman monster. There are no easy answers, and The Cell ... on a harrowing journey. For those who are up to the challenge, it s worth spending time in The Cell . ref http www.reelviews.net php review template.php?identifier 975 Cell, The A movie review by James ... engulfed &mdash shrieking &mdash in flames. The Cell serves up some of the most gruesomely ... . ref http onfilm.chicagoreader.com movies capsules 19239 CELL.html The Cell Capsule by Jonathan Rosenbaum From the Chicago Reader ref The Cell was nominated for the Academy Award for Best ... Baines Jake Thomas as Young Carl Rudolph Stargher Dean Norris as Cole Sequel main The Cell 2 A sequel ... title tt1185837 title The Cell 2 2009 V publisher Imdb.com date 2008 08 20 accessdate 2009 03 02 .... References reflist External links IMDb title 0209958 The Cell Allmovie title 195764 The Cell mojo title cell The Cell Tarsem Singh DEFAULTSORT Cell Category 2000 films Category American films Category ...   more details



  1. Hammer and sickle (disambiguation)

    Hammer and sickle is the international symbol of Communism . Hammer and sickle may also refer to Hammer & Sickle , a computer game Moscow Metallurgical Plant Hammer and Sickle plant , Moscow Hammer and Sickle is also a brand of Vodka. disambig ...   more details




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