Prenylation Prenylation or isoprenylation or lipidation is the addition of hydrophobic molecules to a protein . It is usually .... Protein prenylation Protein prenylation involves the transfer of either a farnesyl or a geranyl ..
Lipid anchored protein
chain of cysteine residues. Prenylation is the attachment of lipid chains to proteins to facilitate their interaction with the cell membrane . Some important prenylation chains are geranylgeraniol ..
C-terminus
domain . Prenylation main Prenylation One form of C terminal modification is prenylation . During prenylation ..
Choroideremia
for the prenylation of Rab G protein Rab proteins. Studies have shown that there is a build up of Prenylation ..
Rab27
Rab subfamily of GTPase s. Rab27 is post translationally modified by the addition of two prenylation ... as type II Griscelli syndrome , while a decrease in Rab27 prenylation is thought to be involved in choroideremia ..
Lapaquistat prenylation ref name pmid16639429 cite journal author Greenwood J, Steinman L, Zamvil SS title Statin therapy and autoimmune disease from protein prenylation to immunomodulation journal Nat. Rev. Immunol ..
Otera?s catalyst
of Spirotryprostatin B via Diastereoselective Prenylation journal Org. Lett. year 2007 doi 10.1021 ..
Geranylgeranyltransferase type 1
terminus of the target protein. This process, called prenylation , causes prenylated proteins ... Prenylation Farnesyltransferase Rab geranylgeranyltransferase Geranylgeranyltransferase type 2 transferase ..
Pt-barrel
for the promiscuous biosynthetic prenylation of aromatic natural products . Nature. 2005 Jun 16 435 ...&query hl 5&itool pubmed docsum Novel prenyltransferase enzymes as a tool for flavonoid prenylation ..
Protein geranylgeranyltransferase type II
WA date Pt 3 title Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases ... prenylation by RabGGTase can proceed without dissociation of the mono prenylated intermediate journal ..
Farnesyltransferase
the more general term prenylation , causes farnesylated proteins to become cell membrane membrane ... number 2.5.1.29 See also Prenylation Farnesyltransferase inhibitor Geranylgeranyltransferase type 1 ..
Rab geranylgeranyltransferase
cell membrane. See also Prenylation Farnesyltransferase Geranylgeranyltransferase type 1 also referred ..
PTP4A1
a PTP domain and a characteristic C terminal prenylation motif. PTPs are cell signaling molecules that play ... depends on its C terminal prenylation. Overexpression of this gene in mammalian cells conferred ..
Cytokinin
diphosphate HMBDP as Prenylation prenyl donors . ref name biosynthesis Ildoo Hwang, Hitoshi Sakakibara ... the adenosine as a cytokinin. ref name biosynthesis The prenylation of these adenines is carried ..
NARF
to be prenylated and methylated at their carboxyl terminal ends. Prenylation was initially believed to be important only for cell membrane membrane attachment . However, another role for prenylation ..
PTP4A2
tyrosine phosphatase catalytic domain and a characteristic C terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C terminal prenylation ..
Mevalonate pathway
of molecules used in processes as diverse as protein prenylation , cell membrane maintenance ..
Rab (G-protein)
Defects in protein prenylation can cause pathologies such as choroideremia . Types of Rab proteins ..
Palmitoylation
to prenylation and myristoylation , palmitoylation is reversible. This allows the cell to dynamically ..
Non-mevalonate pathway
of molecules used in processes as diverse as protein prenylation , cell membrane maintenance, hormones ..
Spirotryprostatin B
by a decarboxylation prenylation sequence, reminiscent of the Carroll reaction . Here, a prenyl ester ... Synthesis of Spirotryprostatin B via Diastereoselective Prenylation journal Org. Lett. volume 9 issue ..
FNTA
al. title Prenylation of an interferon gamma induced GTP binding protein the human guanylate binding ... Zeng Q, Si X, Horstmann H, et al. title Prenylation dependent association of protein tyrosine phosphatases ..
FNTB
pmid 8599089 doi cite journal author Nantais DE, Schwemmle M, Stickney JT, et al. title Prenylation .... title Prenylation dependent association of protein tyrosine phosphatases PRL 1, 2, and 3 with the plasma ..
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