Infobox disease Name HepatitisB ICD10 ICD10 B 16 b 15 , br ICD10 B 18 0 b 15 ICD10 B 18 1 b 15 ICD9 ICD9 070.2 ICD9 070.3 Image HepatitisB virions.jpg Caption Transmission electron microscopy Electron micrograph of hepatitisB virus DiseasesDB 5765 MedlinePlus 000279 eMedicineSubj med eMedicineTopic 992 eMedicine mult eMedicine2 ped 978 MeshID D006509 OMIM 610424 HepatitisB is an infectious inflammatory illness of the liver caused by hepatitisB virus HBV affecting hominoidea , including humans ... in HepatitisB in China China . ref name pmid16941687 Cite doi 10.1002 hep.21347 ref More than 2 billion people have been infected, ref name WHOfactsheet Cite web title HepatitisB url http www.who.int ... HepatitisB url http liver.stanford.edu Education faq.html publisher Stanford School of Medicine ... A, Bl ckberg J, Lindqvist B title High levels of hepatitisB virus DNA in body fluids from chronic ... December pmid 17046105 doi 10.1016 j.jhin.2006.06.029 ref However, HepatitisB viruses cannot be spread ..., or breastfeeding. ref name PubMed Health Cite web title HepatitisB url http www.ncbi.nlm.nih.gov ... CDC HBV Transmission Cite web title HepatitisB FAQ Transmission url http www.cdc.gov hepatitisB ... is preventable by HepatitisB vaccine vaccination . ref name pmid17673066 Cite doi 10.4065 82.8.967 ref HepatitisB virus is an hepadnavirus hepa from hepatotrophic and dna because it is a DNA ... B virus is associated with acute viral hepatitis an illness that begins with general ill health ... author Terrault N, Roche B, Samuel D title Management of the hepatitisB virus in the liver transplantation ... ref Chronic infection with hepatitisB virus may be either asymptomatic or may be associated ... for cirrhosis and liver cancer. HepatitisB virus has been linked to the development of Membranous ... of membranous glomerulopathy secondary to chronic HepatitisB infection year 2005 month ... Gianotti Crosti syndrome . ref name pmid6126007 cite journal author Dienstag JL title HepatitisB as an immune ... more details
Summary Simplified drawing of the HepatitisB virus particle and surface surplus antigen Licensing PD self date November 2007 Orphan image Copy to Wikimedia Commons bot Fbot ... more details
Drugbox Verifiedfields changed verifiedrevid 450879755 image drug name HepatitisB immune globulin Clinical data tradename Drugs.com drugs.com monograph hepatitisb immune globulin pregnancy AU A B1 B2 B3 C D X pregnancy US c A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration intramuscular injection Identifiers ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID NA CAS number Ref cascite correct ?? CAS number ATC prefix J06 ATC suffix BB04 PubChem DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data HepatitisB immune globulin HBIG is a human immune globulin that is used to prevent the development of hepatitisB . Preparation HBIG is prepared from the blood plasma plasma of blood donor donor s who have high antibody levels of the hepatitisB surface antigen. It is extracted from the Cohn Fraction II. During the process, viruses are deactivated, and in the final ... prophylaxis for people at risk to develop hepatitisB because they have been recently exposed to body fluid s of individuals who have hepatitisB. This includes babies of mothers with hepatitisB, sexual partners, healthcare workers, police and fire workers, and morticians. ref http www.mayoclinic.com ... within 14 days of exposure to the hepatitisB virus. ref name blue The half life of HBIG is about 3 weeks. In lieu of a booster administration of HBIG, a hepatitisB vaccination is initiated at the time ... preview mmwrhtml 00022736.htm CDC recommendation for postexposure prophylaxis of hepatitisB Retrieved ... United States U.S. Food and Drug Administration . Brand names Bayhep B HepaGam B HyperHEP B Nabi HB Nabi HB NovaPlus References references See also Needlestick injury Immune sera and immunoglobulins Category Blood products Category Hepatitis Category Medical treatments Category Polyclonal ... more details
Taxobox name Duck hepatitisB virus image image width image caption virus group VII ordo Unassigned familia Hepadnaviridae genus Avihepadnavirus species Duck hepatitisB virus Duck HepatitisB virus , abbreviated DHBV , is part of the Avihepadnavirus genus of the Hepadnaviridae , and is the causal agent of duck hepatitisB. DHBV is a small DNA virus with a diameter of 40 45 nm. The viral envelope is made up from host cell lipid, with viral surface antigens DHBsAg . The icosahedral nucleocapsid within, is composed of the virus core antigen DHBcAg and surrounds the DNA genome and viral polymerase. The viral genome is a circular double stranded DNA molecule about 3000 base pairs long. The genome has three overlapping open reading frames or ORFs C ORF encoding the core antigen and pre core protein which are processed and secreted as DHBcAg S ORF codes for the surface antigen DHBsAg P ORF encoding the viral polymerase. On binding and viral entry entry of the virus to the host cell, the genome is transported to the nucleus to be transcribed. Novel viral RNA is then transferred to the cytoplasm for translation and subsequent protein synthesis. The Duck HepatitisB virus has provided a basis for the use of vaccines and prophylactic treatments for individuals at high risk of human HepatitisB virus HBV . ref cite journal title Immune responses to duck hepatitisB virus infection. author Jilbert AR, Kotlarski I last first authorlink coauthors date 2000 Mar Apr year month work publisher National Center for Biotechnology Information volume 24 issue 2 3 pages 285 302 doi 10.1016 S0145 305X 99 00079 8 pmid 10717294 journal Developmental and comparative immunology ref The virus has ... steps in hepatitisB virus infection. author Cooper A, Paran N, Shaul Y last first authorlink ... et Biophysica Acta ref References Reflist DEFAULTSORT Duck HepatitisB Virus Category Pararetroviruses Category Animal virology cs Virov hepatitida kachen ja B ... more details
Drugbox Verifiedfields changed verifiedrevid 447912967 image drug name HepatitisB vaccine Vacine data type vaccine target HepatitisB vaccine type subunit Clinical data tradename Drugs.com drugs.com monograph hepatitisb vaccine MedlinePlus a607014 pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D ... ChemSpiderID Ref chemspidercite changed chemspider ChemSpiderID NA Chemical data HepatitisB vaccine is a vaccine developed for the prevention of hepatitisBhepatitisB virus infection . The vaccine contains one of the viral envelope proteins , hepatitisB surface antigen HBsAg . It is produced ... recombivax drug.htm title HepatitisB Vaccine from Merck accessdate 2010 05 09 ref A course ... hepb vaccine information.htm title HepatitisB Vaccine date 2009 01 31 publisher HepatitisB ... and immune system memory then provide immunity to hepatitisB infection. ref Cite web url http www.cdc.gov ... B surface antigen HBsAg and injected with hepatitisB immunoglobulin HBIG . ref name pmid16371945 Cite pmid 16371945 ref Many countries now routinely vaccinate infants against hepatitisB. In countries with high rates of hepatitisB infection, vaccination of newborns has not only reduced the risk ... the implementation of a nationwide hepatitisB vaccination program in 1984 was associated with a decline ... NEJM199706263362602 ref In many areas, vaccination against hepatitisB is also required for all health ... 3rd chapter Chapter 12 Immunisation of healthcare and laboratory staff HepatitisB chapterurl http www.dh.gov.uk ... response, which is defined as an HepatitisB virus anti hepatitisB surface antigen anti ... be tested to exclude current or past HepatitisB infection, and given a repeat course of 3 vaccinations ... A and B vaccine. ref Cite pmid 18544037 ref Those who still fail to respond will require hepatitisB immunoglobulin HBIG if later exposed to the hepatitisB virus. ref name isbn0113225288 Poor ... of vaccine. ref name isbn0113225288 At least one study suggests that hepatitisB vaccination is less ... more details
For the disease HepatitisB Taxobox name HepatitisB virus image HepatitisB virus 1.jpg image width 160px image caption Transmission electron microscopy TEM micrograph showing hepatitisB viruses virus group VII ordo Unassigned familia Hepadnaviridae genus Orthohepadnavirus species HepatitisB virus HepatitisB virus , abbreviated HBV , is a species of the genus Orthohepadnavirus , which is likewise ... ref This virus causes the disease hepatitisB. ref name pmid18824707 Disease main HepatitisB In addition to causing hepatitisB, infection with HBV can lead to cirrhosis and hepatocellular ... al. title Solution structure of stem loop alpha of the hepatitisB virus post transcriptional regulatory ... hepatitisB virus and pancreatic cancer journal J. Clin. Oncol. volume 26 issue 28 pages 4557 62 year ... pmidlookup?view long&pmid 18824707 ref Classification The hepatitisB virus is classified as the type ... virus , Woodchuck hepatitis virus , and the Woolly monkey hepatitisB virus . The genus is classified ... International Committee on Taxonomy of Viruses ref Viruses similar to hepatitisB have been found .... ref name pmid15752827 cite journal author Kramvis A, Kew M, Fran ois G title HepatitisB virus ... and molecular epidemiology of the hepatitisB virus as reflected by sequence variability of the S gene ... Structure HepatitisB virus is a member of the Hepadnaviridae Hepadnavirus family . ref name ... of hepatitisB virus journal Semin. Liver Dis. volume 24 issue Suppl 1 pages 3 10 year 2004 pmid ... Components It consists of HBsAg HBcAg HBeAg is a splice variant HepatitisB virus DNA polymerase ... DM, Zhu PA, Liu F title HepatitisB virus X protein promotes proliferation and upregulates TGF beta1 ... Evolution The early evolution of the HepatitisB, like that of all viruses, is difficult to establish ... VV, Kootstra NA, Berkhout B, Zaaijer HL title Protein X of hepatitisB virus origin and structure ... NA, Berkhout B, Zaaijer HL 2011 Protein x of hepatitisB virus origin and structure similarity with the central ... more details
Refimprove date January 2009 HepatitisB is Endemic epidemiology endemic in China . ref Cite web url http www.who.int csr disease hepatitis whocdscsrlyo20022 en index4.html title HepatitisB Surveillance ... worldwide infected with the hepatitisB virus HBV , one third reside in China. ref name pmid15602165 ... of immunization that would limit the spread of hepatitisB effectively. Epidemiology Prevalence Of the 350 million to 400 million individuals worldwide infected with the hepatitisB virus HBV , one third ... journal last CW first Si title Current status and problem of chronic hepatitisB journal Clin Med J ... Nov title Epidemiological Analysis on Reported HepatitisB Under 15 Years in China journal China s immunization ... is unknown, because hepatitisB has no clear transmission routes in many people in China, although ... children living in the country s poorest provinces against hepatitisB according to the Chinese ... is in urgent need of a comprehensive hepatitisB vaccination program. Surveillance is still poor ... burden at 120 million people chronically infected with hepatitisB, one third of the burden 360 ... of chronic hepatitisB. Since many children 5 years of age and older in Qinghai were not vaccinated against the hepatitisB virus at birth, a private public partnership was formed between the Ping ... of a new policy beginning in 2009 to provide free catch up hepatitisB vaccination for all children ... AG s drug Sebivo , a brand name for telbivudine , as a treatment for chronic hepatitisB in February .... The PRC government has set a goal of reducing the overall hepatitisB infection infection rate to less ... hepatitisB that can be prevented by vaccines. But a study of some campaigns shows that more than ... the vaccination. Officials involved in the hepatitisB vaccination programs say that in many ... positive for hepatitisB is either denied employment or fired. Laws do exist to protect the privacy of employees and job seekers but they are not enforced. Research HepatitisB and its related disorders ... more details
notability date June 2010 orphan date May 2010 italictitle Infobox Journal cover discipline Medical research Biomedical website http www.hepatitisbannual.org publisher Medknow Publications country India frequency Annual abbreviation Hep B Annual. history 2004 present ISSN 0972 9747 eISSN 1998 3573 Hepatitis B Annual ISSN Print 0972 9747, Online 1998 3573 is peer reviewed open access journal published on behalf of the Kalinga Gastroenterology Foundation. The journal publishes articles on the subject of Hepatitis B. The journal is indexed with Abstracts on Hygiene and Communicable Diseases , CAB Abstracts, Caspur, DOAJ, EBSCO Publishing s Electronic Databases, Excerpta Medica EMBASE, Expanded Academic ASAP, Genamics JournalSeek, Global Health, Google Scholar, Health & Wellness Research Center, Health Reference Center Academic, Hinari, Index Copernicus, OpenJGate, SCOLOAR, SIIC databases, Tropical Diseases Bulletin, Ulrich s International Periodical Directory. External links http www.hepatitisbannual.org Official Website Category Open access journals Category open access journals Category Medknow Publications academic journals Category Annual journals Category English language journals Category Gastroenterology and hepatology journals ... more details
Image HBV genome.png right thumb 300px The genome organisation of HBV. The genes overlap. ORF P, in blue, encodes Hepatitis B virus DNA polymerase Hepatitis B virus DNA polymerase is a hepatitis B viral protein . ref name pmid10051501 cite journal author Ono Nita SK, Kato N, Shiratori Y, et al. title YMDD motif in hepatitis B virus DNA polymerase influences on replication and lamivudine resistance A study by in vitro full length viral DNA transfection journal Hepatology volume 29 issue 3 pages 939 45 year 1999 month March pmid 10051501 doi 10.1002 hep.510290340 ref ref name pmid8903366 cite journal author Shaw T, Mok SS, Locarnini SA title Inhibition of hepatitis B virus DNA polymerase by enantiomers of penciclovir triphosphate and metabolic basis for selective inhibition of HBV replication by penciclovir journal Hepatology volume 24 issue 5 pages 996 1002 year 1996 month November pmid 8903366 doi 10.1002 hep.510240504 ref It encodes a DNA polymerase . References reflist Viral proteins virus stub Category Viral proteins es Virus de la hepatitis B ADN polimerasa ... more details
Rfam box acc HBV PREalpha description HepatitisB virus PRE alpha abbreviation HBV PREalpha type Cis reg avg length 30 avg identity 00 ss Published PMID 9776740 se PMID 9776740 type Cis reg The HepatitisB virus PREalpha HBV PREalpha is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs. HBV PREalpha consists of a 30 nucleotide nt stem loop, with a 5 nt apical loop. The conserved stem loop was predicted within the HBV PRE sequence and confirmed by mutagenesis . ref cite journal doi 10.1093 nar 26.21.4818 last1 Smith Gj first1 3rd last2 Donello first2 JE last3 L ck first3 R last4 Steger first4 G last5 Hope first5 TJ title The hepatitisB virus post transcriptional regulatory element contains two conserved RNA stem loops which are required for function journal Nucleic Acids Research volume 26 issue 21 pages 4818 27 year 1998 pmid 9776740 pmc 147918 ref The Rfam structure is based on a covariation model. See also HepatitisB virus PRE beta HBV RNA encapsidation signal epsilon References reflist 1 External links Rfam id HBV PREalpha name HepatitisB virus PRE alpha Category Cis regulatory RNA elements molecular cell biology stub ... more details
Rfam box acc HBV PREbeta description HepatitisB virus PRE beta abbreviation HBV PREbeta type Cis reg avg length 23 avg identity 00 ss Published PMID 9776740 se PMID 9776740 type Cis reg The HepatitisB virus PREbeta HBV PREbeta is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs. The minimal HBV PREbeta structure consists of a 23 nt stem loop, with a 9 nt apical loop. The conserved stem loop was predicted within the HBV PRE sequence and confirmed by mutagenesis . ref cite journal doi 10.1093 nar 26.21.4818 last1 Smith Gj first1 3rd last2 Donello first2 JE last3 L ck first3 R last4 Steger first4 G last5 Hope first5 TJ title The hepatitisB virus post transcriptional regulatory element contains two conserved RNA stem loops which are required for function journal Nucleic Acids Research volume 26 issue 21 pages 4818 27 year 1998 pmid 9776740 pmc 147918 ref The Rfam structure is based on a covariation model. See also HepatitisB virus PRE alpha HBV RNA encapsidation signal epsilon References reflist 1 External links Rfam id HBV PREbeta name HepatitisB virus PRE beta Category Cis regulatory RNA elements molecular cell biology stub ... more details
Infobox disease Name Hepatitis A ICD10 ICD10 B 15 b 15 ICD9 ICD9 070.0 , ICD9 070.1 DiseasesDB 5757 MedlinePlus ... from a contaminated river. ref name Murray, P. r. 2005 See also HepatitisBHepatitisB in China Hepatitis ... Hepatitis A formerly known as infectious hepatitis and epidemical virus is an Acute medical acute infectious disease of the liver caused by the hepatitis A virus Hep A , ref name Sherris cite book ... BP title Hepatitis A in the era of vaccination journal Epidemiol Rev volume 28 pages 101 11 year ... cite journal author Connor BA title Hepatitis A vaccine in the last minute traveler journal ... Changing travel related global epidemiology of hepatitis A journal Am. J. Med. volume 118 issue Suppl ... Jacobsen KH, Koopman JS title The effects of socioeconomic development on worldwide hepatitis A virus ... 15831565 ref Hepatitis A infection causes no clinical signs and symptoms in over 90 of infected children ... a relapse of symptoms during the 6 months after acute illness. Acute liver failure from Hepatitis ... to age, with 80 of adults having symptoms compatible with acute viral hepatitis and the majority ... doi 10.1016 S0264 410X 99 00470 3 author Ciocca M. title Clinical course and consequences of hepatitis ... can be prevented by vaccination , and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide. ref name pmid16271543 Signs and symptoms Early symptoms of hepatitis A infection ... cite web title Hepatitis A Symptoms publisher eMedicineHealth url http www.emedicinehealth.com hepatitis a page3 em.htm Hepatitis 20A 20Symptoms date 2007 05 17 accessdate 2007 05 18 ref Symptoms ... title Hepatitis A Information for the Public publisher Center for Disease Control url http www.cdc.gov hepatitis A aFAQ.htm date 2009 09 17 accessdate 2011 01 08 ref Fatigue medical Fatigue Fever Abdominal ... Taxobox name Hepatitis A image Hepatitis A virus 02.jpg image caption electron microscope Electron micrograph of hepatitis A virions. image width 185px virus group iv familia Picornaviridae genus ... more details
involving the liver. Baillieres Clin Gastroenterol 1 2 211 230 ref Hepadnaviridae HepatitisB ... ref name bain Viral hepatitisHepatitisB with or without hepatitis D , hepatitis C neither ... H, H gemann B 1998 Adult giant cell hepatitis with fatal outcome. Clinicopathologic case report and reflections ...Infobox disease Name Hepatitis Image Alcoholic hepatitis.jpg Caption Alcoholic liver disease Alcoholic hepatitis evident by fatty change, cell necrosis , Mallory bodies ICD10 ICD10 K 75 9 k 70 ICD9 ICD9 573.3 DiseasesDB 20061 MedlinePlus eMedicineSubj eMedicineTopic MeshID D006505 Hepatitis plural hepatitides ... on its own or can progress to fibrosis scarring and cirrhosis . Hepatitis may occur with limited ... . Hepatitis is acute when it lasts less than six months and chronic when it persists longer. A group of viruses known as the hepatitis viruses cause most cases of hepatitis worldwide, but it can also ... , diarrhea , and headache . More specific symptom s, which can be present in acute hepatitis from ... I title Acute hepatitis journal BMJ volume 322 issue 7279 pages 151 153 year 2001 pmid 11159575 doi 10.1136 bmj.322.7279.151 pmc 1119417 ref Acute viral hepatitis is more likely to be asymptomatic ... days, with the total illness lasting 2 to 6 weeks. ref name bain V.G. Bain and M. Ma, Acute Viral Hepatitis ... an online text book ref A small proportion of people with acute hepatitis progress ... transplantation liver transplant . Chronic Chronic hepatitis often leads to nonspecific symptoms such as malaise ... be enlargement of the liver. ref name MerckHome MerckHome 10 137 c Chronic hepatitis ref Extensive ... of the thyroid gland and kidney s may be present in women with autoimmune hepatitis . ref ... and a number of pattens have been identified. Liver biopsies are rarely performed for acute hepatitis and because of this the histology of chronic hepatitis is better known than that of acute hepatitis. Acute In acute hepatitis the lesions areas of abnormal tissue predominantly contain diffuse sinusoidal ... more details
or chronic forms. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses Hepatitis A , HepatitisB , Hepatitis C , Hepatitis D , and Hepatitis E . In addition to the hepatitis ... A virus HAV HepatitisB virus HBV Hepatitis C virus HCV Hepatitis D HDV Hepatitis E virus HEV Transmission ... No Yes uncommon Yes common Yes with hepatitisB No Hepatitis A main Hepatitis A Hepatitis A or infectious ... a fact.htm accessdate 2008 03 03 ref HepatitisB main HepatitisBHepatitisB is caused by hepatitisB virus, a hepadnavirus that can cause both acute and chronic hepatitis. Chronic hepatitis develops ... countries as a form of prevention. Patients with chronic hepatitisB have antibodies against hepatitis ... disease seen in these patients. A vaccine is available that will prevent infection from hepatitisB for life. HepatitisB infections result in 500,000 to 1,200,000 deaths per year worldwide due to the complications of chronic hepatitis, cirrhosis , and hepatocellular carcinoma . HepatitisB is Endemic ... hepatitisB infection alpha interferon , pegylated interferon adefovir , entecavir , telbivudine and lamivudine ... C Hepatitis C originally non A non Bhepatitis is caused by hepatitis C virus HCV , an RNA virus ... either hepatitis A or B, so all persons with hepatitis C should be immunized against hepatitis A and hepatitisB if they are not already immune, and avoid alcohol. HCV viral levels can be reduced ... B virus. Hepatitis E main Hepatitis E The Hepatitis E virus HEV produces symptoms similar to hepatitis ...Infobox disease Name Viral hepatitis Image Ground glass hepatocytes high mag cropped 2.jpg Caption Micrograph showing ground glass hepatocytes , which are seen in Chronic medicine chronic hepatitisB infections a type of viral hepatitis , and represent accumulations of virus viral antigen in the endoplasmic reticulum . H&E stain . DiseasesDB ICD10 ICD10 B 15 b 15 ICD10 B 19 b 15 ICD9 ICD9 070 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D006525 Viral hepatitis is Hepatitis liver inflammation ... more details
Orphan date February 2009 refimprove date April 2008 Hepatitis X , also known as the Lost Hepatitis is an acute infectious disease of the liver caused by hepatitis virus, which is most commonly transmitted by the fecal oral route via contaminated food or drinking water. In the United States, approximately 10 people per year are infected with the virus, primarily in the Mid Atlantic region. The time between infection and the appearance of the symptoms, the incubation period , is roughly one week. Often the virus will show itself, but later the patient will lose all symptoms. Roughly one week later the virus will show itself again stronger and more dangerously. ref http www.reference.com ref Some cases of viral hepatitis cannot be ascribed to hepatitis A , hepatitisBB , hepatitis C C , hepatitis D D , or hepatitis E E , so they are called non A...E hepatitis, or hepatitis X. During the diagnostic process for hepatitis X, the possible alternative diagnoses should be considered hepatitis A, B, C, D, and E, and CMV Cytomegalovirus . Early symptoms of hepatitis X infection can be mistaken ... of the abdomen Weight loss Diagnosis and results Hepatitis X often goes undiagnosed by doctors due to the difficulty ... http www.reference.com ref Complications The distinction between complications of hepatitis X and symptoms of hepatitis X is often obscure. While jaundice yellow discoloration of the skin or whites of the eyes due to an increase of bile pigments in the blood , is a symptom of hepatitis, it is also ..., and CSF xanthochromia. Liver disease is another fatal complication of hepatitis X. This could potentially .... ref http www.wrongdiagnosis.com h hepatitis x intro.htm ref Treatment There has been no specific drug therapy developed for hepatitis, with the exception of hepatitis C. Patients are advised to rest ... if signs of precoma lethargy, confusion, and mental changes develop. In acute viral hepatitis ... h hepatitis x intro.htm ref References reflist Category Hepatitis ... more details
1 antitrypsin deficiency, HepatitisB and C and drug induced hepatitis have been ruled out, a possible ...Mergeto Autoimmune hepatitis date October 2011 Orphan date November 2006 Refimprove date September 2011 Lupoid hepatitis also called autoimmune hepatitis is an auto immune disease which causes liver cirrhosis ... s. 60 of patients have chronic hepatitis that may mimic viral hepatitis, but without serology serologic ... with anti smooth muscle auto antibody antibodies . Autoimmune hepatitis is a condition in which the patient ... is chronic and progressive. Although the disease is chronic, many patients with autoimmune hepatitis ..., a picture that resembles acute hepatitis. Autoimmune hepatitis usually occurs in women 70 between the ages of 15 and 40. Although the term lupoid hepatitis was originally used to describe this disease, patients with systemic lupus erythematosus do not have an increased incidence of autoimmune hepatitis ... to severe hepatitis with elevated serum ALT and AST activities in the setting of normal to marginally ... hepatitis journal New England Journal of Medicine volume 334 pages 897 903 doi 10.1056 NEJM199604043341406 pmid 8596574 issue 14 ref Autoimmune hepatitis is a chronic inflammatory disease of the liver ... ruled out. Autoimmune hepatitis was previously called lupoid hepatitis. It was originally described ... erythematosis. Thus, its name was previously lupoid hepatitis. Because the disease has multiple different forms, and is not always associated with systemic lupus erythematosis, lupoid hepatitis is no longer used. The current name at present is autoimmune hepatitis IAH . Diagnosis Patients who have chronic elevations in liver function tests for greater than 6 months are thought to have chronic hepatitis .... Evaluation for these types of autoimmune hepatitis is obtained through simple blood tests. Based upon .... Treatment Not all patients with autoimmune hepatitis require treatment. However, when they have .... In general, patients do quite well with autoimmune hepatitis. Treatment is usually required ... more details
Taxobox name Hepatitis D image image width image caption virus group v ordo Unassigned familia Unassigned genus Deltavirus species Hepatitis delta virus Infobox disease Name Hepatitis D Image Caption DiseasesDB ICD10 ICD10 B 17 0 b 15 , ICD10 B 18 0 b 15 ICD9 ICD9 070.31 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D003699 Hepatitis D , also referred to as hepatitis D virus HDV and classified as Hepatitis delta virus , is a disease caused by a small circular enveloped RNA virus . It is one of five known hepatitis viruses hepatitis A A , hepatitisBB , hepatitis C C , D, and hepatitis ... in the presence of the hepatitisBhepatitisB virus HBV . ref cite journal author Makino S title Molecular cloning and sequencing of a human hepatitis delta delta virus RNA journal Nature volume 329 ... either via simultaneous infection with HBV coinfection or superimposed on chronic hepatitisB or hepatitisB carrier state superinfection . Both superinfection and coinfection with HDV results in more ... B virus, hepatitis D has the highest mortality rate of all the hepatitis infections of 20 . Virology ... antibody system delta anti delta associated to hepatitisB virus in liver and in serum of HBsAg ... gut.18.12.997 ref This nuclear antigen was then thought to be a hepatitisB antigen and was called the delta ... coat containing three HBV envelope proteins called large, medium, and small hepatitisB surface ... title Mapping of the HepatitisB Virus Pre S1 Domain Involved in Receptor Recognition journal Journal ..., P, Gripon, P, Schn lzer, M, Urban, S title Characterization of a hepatitisB and hepatitis delta ... of hepatitis D are similar to those for hepatitisB. Infection is largely restricted to persons at high risk of hepatitisB infection, particularly injecting drug users and persons receiving clotting ... ref See also Hepatitis A HepatitisB and HepatitisB in China Hepatitis C Hepatitis E Hepatitis ... Fattovich G title Influence of hepatitis delta virus infection on morbidity and mortality in compensated ... more details
Infobox disease Name Hepatitis E Image Hepatitis E virus.jpg Caption Hepatitis E virus ICD10 ICD10 B 17 2 b 15 ICD9 ICD9 070.4 DiseasesDB 5794 MedlinePlus eMedicineSubj med eMedicineTopic 995 MeshID D016751 Hepatitis E is a viral hepatitis liver inflammation caused by infection with a virus called hepatitis ... genome. HEV has a fecal oral transmission route. It is one of five known hepatitis viruses hepatitis A A , hepatitisBB , hepatitis C C , hepatitis D D , and E. Infection with this virus was first ... HF title The histopathology of viral hepatitis as seen in the Delhi epidemic 1955 56 journal Indian ... cite journal author Guu TS, Liu Z, Ye Q, et al. title Structure of the hepatitis E virus .... ref name Purdy2010 Purdy MA, Khudyakov YE 2010 Evolutionary history and population dynamics of hepatitis E virus. PLoS One 5 12 e14376. ref Epidemiology The incidence of hepatitis E is highest in juveniles ..., they less frequently become symptomatic. Mortality rates are generally low, for hepatitis E is a self ... to work, care for family members, and obtain food. Hepatitis E occasionally develops into an acute ... to hepatitis A , but in pregnant women the disease is more often severe and is associated with a clinical ... animal species and have been responsible for sporadic cases of hepatitis E in both developing ... al. title Acute hepatitis due to hepatitis E virus genotype 1 as an imported infectious disease in Japan ... in treatment is not yet clear. Population genetics The most recent common ancestor of Hepatitis ... history and population dynamics of hepatitis E virus. PLoS One 5 12 e14376. ref It diverged ... YE 2010 Evolutionary history and population dynamics of hepatitis E virus. PLoS One 5 12 e14376 ... dynamics of hepatitis E virus. PLoS One 5 12 e14376. ref The population size of genotype ... and population dynamics of hepatitis E virus. PLoS One 5 12 e14376. ref Patterns Hepatitis E is prevalent .... Outbreaks of epidemic hepatitis E most commonly occur after heavy rainfalls and monsoons because ... more details
, Horyniak, D, Degenhardt, L title Global epidemiology of hepatitisB and hepatitis C in people who ..., PB, Langan, RC title Caring for pregnant women and newborns with hepatitisB or C. journal American ... name AFP2010 As well they should be vaccinated for hepatitis A and hepatitisB . ref name AFP2010 ..., BP, Gluud, C title Milk thistle for alcoholic and or hepatitisB or C virus liver diseases. journal ... were not due to hepatitis A or HepatitisBB viruses. Despite this discovery, international research efforts to identify the virus, initially called non A, non Bhepatitis NANBH , failed for the next ... of a cDNA clone derived from a blood borne non A, non B viral hepatitis genome journal Science ... antibodies to a major etiologic virus of human non A, non Bhepatitis journal Science volume 244 ...Infobox disease Name Hepatitis C Image HCV EM picture 2.png Caption Electron micrograph of hepatitis C virus purified from cell culture. The scale 50 nanometers DiseasesDB 5783 ICD10 ICD10 B 17 1 b 15 , ICD10 B 18 2 b 15 ICD9 ICD9 070.70 , ICD9 070.4 , ICD9 070.5 OMIM 609532 MedlinePlus 000284 eMedicineSubj med eMedicineTopic 993 eMedicine mult EMedicine2 ped 979 MeshID D006526 Hepatitis C is an infectious disease primarily affecting the liver , caused by the hepatitis C virus HCV . ref name ... varices . ref name Sherris The hepatitis C virus is spread by primarily by blood to blood contact ... recurs after transplantation. An estimated 130 170 million people worldwide are infected with hepatitis C. No vaccine against hepatitis C is currently available. The existence of hepatitis C originally non A non Bhepatitis was postulated in the 1970s and proven in 1989. ref name pmid19781804 cite journal author Houghton M title The long and winding road leading to the identification of the hepatitis .... TOC limit 3 Signs and symptoms Acute infection Hepatitis C infection causes acute symptoms in 15 ... hepatitis C. journal Lancet date 2008 Jul 26 volume 372 issue 9635 pages 321 32 pmid 18657711 ref For those ... more details
vaccine target Hepatitis A vaccine type Killed Clinical data tradename Drugs.com drugs.com CDI hepatitis a vaccine MedlinePlus a695003 pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category ... CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US ... ChemSpiderID NA DrugBank Ref drugbankcite correct drugbank Chemical data Hepatitis A vaccine is a vaccine against the hepatitis A virus. The first successful vaccine against it was invented by Maurice ... S, McMahon B, Van Herck K, Shouval D, Bonanni P, Connor B, Cooksley G, Leroux Roels G, Von Sonnenburg F International Consensus Group on Hepatitis A Virus Immunity, 2003. Hepatitis A booster vaccination is there a need? Lancet. 2003 Sep 27 362 9389 1065 71. ref . The vaccine contains inactivated Hepatitis ... info cite web title Hepatitis A Vaccine Information work Vaccine Information publisher ImmunizationInfo ... 2006 cite web title Hepatitis A Vaccine What you need to know work Vaccine Information Statement publisher ... 2007 03 12 ref Hepatitis A is the most common vaccine preventable virus acquired during travel, ref name CDC Yellow Book cite web title Hepatitis, Viral, Type A work Travelers Health Yellow Book CDC ... CDC 2006 ref name NHS 2006 cite web title Hepatitis A Introduction publisher NHS Direct url http www.nhsdirect.nhs.uk ... against Hepatitis A begins approximately two to four weeks after the initial vaccination ref name ... TW, et al title Persistence of antibody to Hepatitis A virus 10 years after vaccination among ... Avaxim 160U Packaging This may not be a comprehensive list of all commercial Hepatitis A vaccines available ... test they use to measure Hepatitis A antigen in their products. Avaxim made by Sanofi Pasteur . Inactivated Hepatitis A virus produced in MRC 5 cells. Each dose contains 160 U of antigen adsorbed on aluminium ... of synthetic lipids and influenza proteins in addition to the Hepatitis A antigen. It does not contain ... November 2010. ref Havrix made by GlaxoSmithKline . Inactivated Hepatitis A virus produced in MRC 5 ... more details
Unreferenced date August 2008 Infobox disease Name Neonatal hepatitis Image Alt Caption DiseasesDB ICD10 ICD9 ICD9 774.4 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Neonatal hepatitis or perinatal hepatitis is a rare fulminant disease of the liver , of unknown etiology, characterized by massive deposition of iron in the liver, pancreas , heart , and endocrine glands symptoms are those of infant neonatal hepatitis and appear in utero or within the first week of life, with death usually occurring by 4 months of age. Neonatal hepatitis is histologically characterized by the presence of multinucleated giant cells. There may also be bile pigment or hemosiderin within hepatocytes. medical stub Category Pediatrics Category Hepatology ... more details
Orphan date February 2009 Refimprove date January 2009 Italic title Hepatitis Monthly is a medical journal published by the Baqiyatallah Research Center for Gastroenterology and Liver Diseases Tehran , Iran . It is the official journal of this center and of the Iran Hepatitis Network . It was established in 2002 by Seyed Moayed Alavian, who is the journal s editor in chief . ref http hepmon.com page ?id 4 Hepatitis Monthly Homepage ref Abstracting and indexing According to the Journal Citation Reports , the journal s 2009 impact factor is 0.716. In addition, the journal is abstracted and indexed in Science Citation Index Science Citation Index Expanded , Scopus , EMBASE , Index Medicus , and CAB International CABI . References references External links Official http www.hepmon.com http www.hep.ir Iran Hepatitis Network http www.brcgl.ir Baqiyatallah Research Center for Gastroenterology and Liver Diseases Category Publications established in 2002 Category Gastroenterology and hepatology journals ... more details
unreferenced date December 2007 Ischemic hepatitis also known as shock liver is a condition of decreased blood supply to the liver resulting in injury to liver cells hepatocyte s , which occurs in a diffuse fashion. The decreased blood flow perfusion to the liver is usually due to shock or low blood pressure. However, local causes involving the hepatic artery that supplies oxygen to the liver, such as sickle cell anemia sickle cell crisis and thrombosis of the hepatic artery, can also cause ischemic hepatitis. Patients with ischemic hepatitis are usually very ill. Diagnosis and presentation Blood testing usually shows high levels of the liver function tests liver transaminase enzymes, AST and ALT, which may exceed 1000 U L. ref name pmid19473435 cite journal author Raurich JM, P rez O, Llompart Pou JA, Ib ez J, Ayestar n I, P rez B rcena J title Incidence and outcome of ischemic hepatitis complicating septic shock journal Hepatol. Res. volume 39 issue 7 pages 700 5 year 2009 month July pmid 19473435 doi 10.1111 j.1872 034X.2009.00501.x url http www3.interscience.wiley.com resolve openurl?genre article&sid nlm pubmed&issn 1386 6346&date 2009&volume 39&issue 7&spage 700 ref Normal limits for ALT is usually 63 U L, depending on the lab. These increased lab values are due to the injured hepatocytes leaking out these enzymes into the blood stream. People who develop ischemic hepatitis may have pain in the right upper part of the abdomen, but they usually feel more unwell because of the serious reason that they developed the ischemia, than due to the ischemic hepatitis itself. Jaundice can occur, but is rare and transient, as is actual loss of function of the liver. Related conditions Ischemic hepatitis is related to another condition called nutmeg liver congestive hepatopathy or nutmeg liver, which is a backflow condition due to poor drainage of the liver, usually due to heart failure. As a result, the two entities can co exist. See also Elevated transaminases References ... more details
Infobox disease Name Autoimmune hepatitis Image Autoimmune hepatitis cropped very high mag.jpg Caption Micrograph showing a lymphoplasmacytic interface hepatitis the characteristic histomorphologic finding of autoimmune hepatitis. Liver biopsy . H&E stain . DiseasesDB 1150 ICD10 ICD10 K 75 4 k 70 ICD9 ... Hepatitis is a disease of the liver that occurs when the body s immune system attacks cells of the liver ... hepatitis. This abnormal immune response results in inflammation of the liver, which can lead to further complications, including cirrhosis . ref name urlDigestive Disease Autoimmune Hepatitis ... Autoimmune Hepatitis author National Digestive Diseases Information Clearinghouse accessdate October 9, 2010 , ref Autoimmune hepatitis has an incidence of 1 2 per 100,000 per year, and a prevalence of 10 ... 70 . ref name urlAutoimmune Hepatitis cite web url http www.cumc.columbia.edu dept gi autoimmune.html title Autoimmune Hepatitis work accessdate ref Liver enzyme s are elevated, as may be bilirubin . Classification ... ref name urlautoimmune hepatitis cite web url http www.meddean.luc.edu Lumen MedEd orfpath autoimmune 20hepatitis.htm title autoimmune hepatitis work accessdate ref this group behaves like group 1 ref ... diagnosis of autoimmune hepatitis is best achieved with a combination of clinical trial clinical , laboratory ... hepatitis always requires a liver biopsy . In complex cases, a scoring system can be used to help determine if a patient has autoimmune hepatitis, which combines clinical and laboratory features ... International Autoimmune Hepatitis Group Report review of criteria for diagnosis of autoimmune hepatitis journal J. Hepatol. volume 31 issue 5 pages 929 38 year 1999 month November pmid 10580593 ... 2008 05 09 ref ref name urlAutoimmune Hepatitis Calculator cite web url http homepage.mac.com sholland contrivances aihcalc.html title Autoimmune Hepatitis Calculator work accessdate 2008 05 ... Autoimmune hepatitis classification, heterogeneity, and treatment journal Am. J. Med. volume 96 issue ... more details
Infobox Disease Name Alcoholic hepatitis Image Mallory body high mag cropped.jpg Caption Micrograph showing a Mallory body , a histopathologic finding associated with alcoholic hepatitis . H&E stain . DiseasesDB ICD10 ICD10 K 70 1 k 70 ICD9 ICD9 571.1 ICDO OMIM MedlinePlus 000281 eMedicineSubj eMedicineTopic 101 MeshID D006519 Alcoholic hepatitis is hepatitis inflammation of the Human liver liver due to excessive intake of Alcoholic beverage alcohol . While distinct from cirrhosis , it is regarded as the earliest stage of alcoholic liver disease . Symptoms are jaundice , ascites fluid accumulation in the abdominal cavity , Fatigue medical fatigue and hepatic encephalopathy Human brain brain dysfunction due to liver failure . Mild cases are self limiting, but severe cases have a high risk of death . Severe cases may be treated with glucocorticoids . Symptoms and signs Alcoholic hepatitis is characterized by a variable constellation of symptoms, which may include feeling unwell, enlargement of the liver, development of fluid in the abdomen ascites , and modest elevation of liver enzyme levels as determined by liver function tests . Alcoholic hepatitis can vary from mild with only liver enzyme elevation to severe liver inflammation with development of jaundice, prolonged prothrombin time , and even liver failure. Severe cases are characterized by either obtundation dulled consciousness ... in both severe categories is 50 within 30 days of onset. Alcoholic hepatitis is distinct from cirrhosis caused by long term alcohol consumption. Alcoholic hepatitis can occur in patients with chronic alcoholic liver disease and alcoholic cirrhosis. Alcoholic hepatitis by itself does not lead to cirrhosis ... develop acute hepatitis as an inflammatory reaction to the cells affected by Steatosis fatty change ... O title Pentoxifylline improves short term survival in severe acute alcoholic hepatitis a double blind ... DEFAULTSORT Alcoholic Hepatitis Category Hepatitis Category Inflammations Category Alcohol abuse ... more details
Encyclopedia
top
