Encyclopedia results for erlotinib

1. Erlotinib
   
   amine image Erlotinib Structural Formulae.png width 250 image2 Erlotinib 1m17 3D balls.png CASNo Ref ... licence EU Tarceva licence US Erlotinib Erlotinib hydrochloride originally coded as OSI 774 is a medication ..
   
   
   
   
2. Catalytic receptor
   
   , epiregulin , Heparin binding EGF like growth factor HB EGF , TGF alpha TGFa GW583340, gefitinib , erlotinib ... Gene ERBB3 Neuregulin 1 NRG 1 , NRG2 NRG 2 GW583340, gefitinib, erlotinib, tyrphostins AG879 and AG1478 ..
   
   
   
   
3. Targeted therapy
   
   are inhibited. Erlotinib marketed as Tarceva . Erlotinib inhibits epidermal growth factor receptor ... 1 2 ref and works through a similar mechanism as gefitinib. Erlotinib has been shown to increase survival ..
   
   
   
   
4. Nanjing Ange Pharmaceutical
   
   , which include Sunitinib Lapatinib Nilotinib Dasatinib Gefitinib Erlotinib Imatinib Canertinib ..
   
   
   
   
5. OSI Pharmaceuticals
   
   peptidase IV inhibitor intellectual property. ref name GENENG200706 Tarceva seealso Erlotinib Tarceva Erlotinib was OSI s Wikt flagship flagship and, as of 2007, only marketed product. ref name ..
   
   
   
   
6. ATC code L01
   
   Imatinib L01XE02 Gefitinib L01XE03 Erlotinib L01XE04 Sunitinib L01XE05 Sorafenib L01XE06 Dasatinib ..
   
   
   
   
7. Protein kinase inhibitor
   
   molecule only Ph 1 ?? Sunitinib multiple targets Pfizer Small molecule 2006 Jan RCC & GIST Erlotinib ..
   
   
   
   
8. Drug eruption
   
   , in drug induced lupus erythematosus , or the acne like rash caused by erlotinib . A skin biopsy , blood ..
   
   
   
   
9. Genentech
   
   , and sixth approval for the treatment of metastatic renal cell carcinoma . 2004 Erlotinib Tarceva erlotinib Treatment for patients with locally advanced or metastatic non small cell lung cancer , and pancreatic ..
   
   
   
   
10. Polycythemia vera
    
    . There are indications that with certain genetic markers, Erlotinib may be an additional treatment ... X, Zhao Z title Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth ..
    
    
    
    
11. ErbB
    
    in many cancers. Drugs such as cetuximab , gefitinib , erlotinib are used to inhibit it. It has ..
    
    
    
    
12. Head and neck cancer
    
    , erlotinib , and reovirus . The best quality data are available for cetuximab since the 2006 publication ... as of that date. Erlotinib is an oral EGFR inhibitor, and was found in one Phase II clinical trial to retard ..
    
    
    
    
13. Annual pharmaceutical drug sales
    
    1,746 1,132 554.6 erlotinib Tarceva Advanced metastatic non small cell lung cancer NSCLC Genentech ..
    
    
    
    
14. Pancreatic cancer
    
    cancer, the US FDA has licensed the use of erlotinib Tarceva in combination with gemcitabine as a palliative regimen for pancreatic cancer. This trial compared the action of gemcitabine erlotinib vs ..
    
    
    
    
15. Insulin-like growth factor 1 receptor
    
    cancer, where Epidermal growth factor receptor EGFR inhibitors such as erlotinib are being used ... see the description of EGFR signal transduction in the erlotinib page , allowing EGFR signaling ..
    
    
    
    
16. Cholangiocarcinoma
    
    of newer targeted therapy targeted therapies such as erlotinib or photodynamic therapy for treatment ... ref A small pilot study suggested possible benefit from the tyrosine kinase inhibitor erlotinib ..
    
    
    
    
17. Somatic evolution in cancer
    
    Iressa and Erlotinib Tarceva are epidermal growth factor receptor EGFR tyrosine kinase inhibitors ... clinical resistance to Gefitinib or Erlotinib ref cite journal author Engelman JA, Jänne PA title ..
    
    
    
    
18. Epidermal growth factor receptor
    
    pages 1497 500 year 2004 month June pmid 15118125 doi 10.1126 science.1099314 url ref and erlotinib ... , and matuzumab . Gefitinib , erlotinib , and lapatinib mixed EGFR and ERBB2 inhibitor are examples ..
    
    
    
    
19. List of bestselling drugs
    
    align center 155 Tarceva Erlotinib align right 649 align right 110 Roche , Genentech Non small cell ..
    
    
    
    
20. Lung cancer
    
    Infobox disease Name Lung cancer Image cancerous lung.jpg Caption Cross section of a human lung. The white area in the upper lobe is cancer the black areas are discoloration due to Tobacco smoking smo ...
    
    
    
    
21. List of oncology-related terms
    
    ER Estrogen receptor ER ERA 923 erb 38 immunotoxin ErbB1 ERCP erlotinib ERT ERUS erythema erythrocyte ..
    
    
    
    
22. Colorectal cancer
    
    Bortezomib Velcade Oblimersen Genasense, G3139 Gefitinib and Erlotinib Tarceva Topotecan Hycamtin Radiation ..
    
    
    
    

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