Unreferenced stub date December 2009 Orphan date December 2009 Allograft diseases are those in which cancerous cells are spread between individuals of the same species by physical contact. To date only two such diseases have been discovered, these are Devil facial tumour disease found in the Tasmanian Devil and Canine transmissible venereal tumor canine transmissible venereal tumour which infects dogs. See also Alloimmunity DEFAULTSORT Allograft Diseases Category Types of animal cancers Veterinary med stub ... more details
Demineralized freeze dried bone allograft , referred to as DFDBA , is a bone graft material known for its de novo bone formation properties. ref Bowers, GM, et al. Histologic evaluation of new attachment apparatus formation in humans . J Perio 1989 60 683 693 ref It is used extensively in bone grafting of alveolar bone in oral surgery oral and periodontology periodontal surgery. References Reflist Category Dentistry definitions Category Skeletal system ... more details
Orphan date April 2010 Osteopromotive describes a material that promotes the de novo formation of bone . Osteoconductivity describes the property of graft material in which it serves as a scaffold for new bone growth but does not induce bone growth de novo . This means that osteoconductive materials will only contribute to new bone growth in an area where there is already vital bone. Osteoinductivity describes the property of graft material in which it induces de novo bone growth with biomimetic substances, such as bone morphogenetic protein s. Such materials will contribute to new bone growth in an area where there is no vital bone, such as when implanted into muscle tissue. ref name Boyan Boyan, BD, et al. u Porcine fetal enamel matrix derivative enhances bone formation induced by demineralized freeze dried bone allograft in vivo u . J Perio 2000 71 1278 1286 ref In contrast, osteopromotive substances will not contribute to de novo bone growth but serve to enhance the osteoinductivity of osteoinductive materials. An example of this is enamel matrix derivative , which serves to enhance the osteoinductive nature of demineralized freeze dried bone allograft DFDBA . ref name Boyan References Reflist Category Skeletal system Category Growth factors ... more details
Orphan date February 2009 The meniscus anatomy meniscus is the cartilage in the knee which separates the thigh bone femur from the lower leg bone tibia . A meniscus transplant consists of taking out a worn or damaged meniscus and replacing it with a new one from a donor. The meniscus to be transplanted is taken from a cadaver , and, as such, is known as an allograft . Meniscal transplantation is relatively technically simple, since the meniscus is avascular throughout most of its structure. The procedure is still not 100 satisfactory but is being researched. External links http www.nlm.nih.gov medlineplus ency article 007209.htm Procedure description http www.stjohn.org innerpage.aspx?PageID 338 Procedure description treatment stub Category Surgery ... more details
Demineralized bone matrix DBM is allograft bone that has had the inorganic mineral removed, leaving behind the organic collagen matrix. It was first discovered by Marshall Urist in 1965 that the removal of the bone mineral exposes more biologically active bone morphogenetic proteins . ref Urist, Marshall R. 1965 . Bone formation by autoinduction . Science 12 150 698 893 899. doi 10.1126 science.150.3698.893. PMID 5319761. ref These growth factors modulate the differentiation of progenitor cells into osteoprogenitor cells, which are responsible for bone and cartilage formation. As a result of the demineralization process, DBM is more biologically active than undemineralized bone grafts conversely the mechanical properties are significantly diminished. Current Clinical Options The success of a bone graft is determined by its ability to recruit host cells to the site of the graft and modulate their conversion into bone forming cells such as osteoblasts , to repair the defect. This will depend on the osteoconductive , osteoinductive and osteogenic capabilities of the graft. Currently, autograft bone harvested from the iliac crest is considered the gold standard due to its superior osteogenic properties. However, associated donor site morbidity , an increased surgery and recovery time, and a limited supply of donor bone are limiting its use ref Graham, S.M., et al., Biological therapy of bone defects the immunology of bone allo transplantation. Expert Opinion on Biological Therapy, 2010. 10 6 p. 885 901. ref . Allograft bone is logical alternative to autograft. However, it must be rigorously processed and terminally sterilized prior to implantation to remove the risk of disease transmission or an immunological response. This processing removes the osteogenic and osteoinductive properties of the graft, leaving only an osteoconductive scaffold . These scaffolds are available .... DBM has superior biological properties to undemineralised allograft bone ref Glowacki, J., S. Zhou ... more details
orphan date December 2008 PBB geneid 199 Allograft inflammatory factor 1 is a protein that in humans is encoded by the AIF1 gene . ref name pmid8912632 cite journal author Autieri MV title cDNA cloning of human allograft inflammatory factor 1 tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries journal Biochem Biophys Res Commun volume 228 issue 1 pages 29 37 year 1996 month Dec pmid 8912632 pmc doi 10.1006 bbrc.1996.1612 ref ref name entrez cite web title Entrez Gene AIF1 allograft inflammatory factor 1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 199 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti inflammatory response to vessel wall trauma. The gene expresses three transcripts. ref name entrez cite web title Entrez Gene AIF1 allograft inflammatory factor 1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 199 accessdate ref References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Deininger MH, Meyermann R, Schluesener HJ title The allograft inflammatory factor 1 family of proteins. journal FEBS Lett. volume 514 issue 2 3 pages 115 21 year 2002 pmid 11943136 doi 10.1016 S0014 5793 02 02430 4 cite journal author Jia J, Zhao YF, Zhao JH title Potential roles of allograft inflammatory factor 1 in the pathogenesis of hemangiomas ... of allograft inflammatory factor 1 a novel macrophage factor identified in rat cardiac ... 8499947 doi 10.1038 ng0293 137 cite journal author Utans U, Quist WC, McManus BM, et al. title Allograft ... The allograft inflammatory factor 1 in Creutzfeldt Jakob disease brains. journal Neuropathol. Appl ... more details
ref transplantation. When a host mounts an immune response against an allograft or xenograft ... transplant s bone allograft ligament or tendon allograft Bone and tissue allografts have many uses ... takes tissue from one part of your body for transplantation to another part. Using an allograft eliminates ... . See also Allograft diseases Medical grafting External links http www.aatb.org files safetyoftissuetransplants.pdf ... more details
FRA may refer to Federal Recovery Administration , Fugitive Marshals Fact date May 2009 Federal Railroad Administration , a division of the United States Department of Transportation Wireless local loop , also known as fixed radio access Fathers rights movement Fathers Rights Activists Fleet Reserve Association Forward rate agreement FRA the ISO 3166 1 ISO 3 letter country code Framingham MBTA station Frankfurt Airport , IATA airport code Frankfurt Stock Exchange Franklin Road Academy Founderless Regions Alliance an organization of hypocrites and cutthroats. F rsvarets radioanstalt , the Swedish National Defence Radio Establishment The FRA law , a controversial surveillance law passed in Sweden Fell Running Association Frequency response analysis Femoral Ring Allograft European Union Fundamental Rights Agency Future Rockstars of America , also known as FRA Clothing & Agency Flash Recovery Area , an Oracle Database technology FRA can also refer to a Fugitive Recovery Agent, a Bounty Hunter disambig de FRA es FRA eo FRA fr FRA ko FRA it FRA lv FRA lt FRA nl FRA ja FRA no FRA pl FRA pt FRA sv FRA olika betydelser ... more details
LDA may refer to In aviation Localizer Type Directional Aid Landing distance available, see Runway Declared distances In law Legal drinking age Legal document assistant In medicine Left displaced abomasum Living donor allograft Low dose allergens, a variant of enzyme potentiated desensitization In science , technology and mathematics Laser Doppler velocimetry Laser Doppler anemometry Latent Dirichlet allocation , a type of topic model Linear diode array Linear discriminant analysis , a type of statistical analysis Lithium diethylamide Lithium diisopropylamide LoaD Accumulator, an opcode from the MOS Technology 6502 instruction set Local delivery agent, a synonym for mail delivery agent Local density approximation , in quantum mechanical density functional theory Low density amorphous ice Other meanings Lahore Development Authority Late Discovery Adoptees, people discovering adoptee status later in life Les Deux Alpes , a ski resort in France. Liga Deportiva Alajuelense , a Costa Rican football club London Democratic Association London Development Agency Lyme Disease Association disambig de LDA fa LDA fr LDA it LDA ja LDA ... more details
Lieutenant colonel United States Lieutenant Colonel Robert A. Bob Bowden b. in Irving, Texas is currently an Professor assistant professor in the Chemistry department at the United States Military Academy . Bowden received his Bachelor of Arts B.A. and Doctor of Philosophy Ph.D. in Veterinary medicine veterinary pathobiology immunology from Texas A&M University . He is a published researcher, with articles appearing in AJP Cell Physiology and Infection and Immunity . His most recent work is Long term Aciclovir acyclovir for prevention of varicella zoster virus disease after Allograft allogeneic Hematopoietic stem cell transplantation hematopoietic cell transplantation a randomized double blind double blind placebo controlled study , which was published in the March 2007 issue of Blood journal Blood . External links http www.dean.usma.edu departments Chem FacultyAndStaff Bowden BowdenR.htm LTC Bowden s page at the USMA Persondata NAME Bowden, Bob ALTERNATIVE NAMES SHORT DESCRIPTION United States Army officer DATE OF BIRTH PLACE OF BIRTH Irving, Texas DATE OF DEATH PLACE OF DEATH DEFAULTSORT Bowden, Robert A. Category Year of birth missing living people Category Living people Category People from Irving, Texas Category Texas A&M University alumni Category United States Army officers Category United States Military Academy faculty US military bio stub ... more details
Orphan date February 2009 Expert subject Biology date November 2008 Context date July 2008 Iba1 ionized calcium binding adaptor molecule 1 is a 17 kDa EF hand protein that is specifically expressed in macrophage s microglia and is upregulated during the activation of these cells. ref cite web work IHC World title Iba1 Antibody Staining Protocol for Immunohistochemistry url http www.ihcworld.com protocols antibody protocols iba1 wako.htm date 2008 04 12 accessdate 2008 07 20 ref The protein is the gene product of the Aif1 gene allograft inflammatory factor 1 which is located within a segment of the major histocompatibility complex class III region. It has been shown that this gene is highly expressed in testis and spleen, but weakly expressed in brain, lung, and kidney. Among brain cells, the Iba1 gene was specifically expressed in microglia. Upon activation of microglia due to inflammation, expression of Iba1 is upregulated allowing the discrimination between surveiling and activated microglia. References reflist Category Proteins protein stub ... more details
Direct and indirect alloantigen recognition are two mechanisms by which T cells may recognize alloantigen s and lead to transplant rejection after an organ transplant . Direct alloantigen recognition Donor tissue macrophages migrate to lymph node s, stimulate a measurable percentage of recipient T cells . The host T cells in the lymph node recognize either the allograft HLA or an associated bound peptide . In this case, alloreactive T cells are stimulated by donor APCs which express both the allogeneic MHC and costimulatory activity . Indirect alloantigen recognition Host organ recipient macrophage s process proteins from the transplanted graft, and trigger a T cell response. Presentation may occur via MHC class I or MHC class II , although class II is usually involved. The main difference between indirect and direct alloantigen recognition stems from the origin of the macrophages type of APC . In direct alloantigen recognition, the involved macrophages are donor derived. In indirect alloantigen recognition, the macrophages APCs involved are recipient. med stub Category Immune system Category T cells ... more details
Allograft Autograft div Bone grafting is possible because bone tissue, unlike most other tissues ... the osteoinductive effect of demineralized freeze dried bone allograft DFDBA , but will not stimulate ... dried bone allograft in vivo journal J. Periodontol. volume 71 issue 8 pages 1278 86 year 2000 month ... action, as there is no solid bony structure. File RightFemurV.JPG thumb 280px A bone allograft. Allografts Allograft bone, like autogenous bone, is derived from humans the difference is that allograft is harvested from an individual other than the one receiving the graft. Allograft bone ... allograft available ref http www.cdc.gov OralHealth Infectioncontrol faq allografts.htm Bone Allografts ref Fresh or fresh frozen bone Freeze dried bone allograft FDBA Demineralized freeze dried bone allograft DFDBA Synthetic variants File Hydrogel HA.jpg thumb 120px Flexible hydrogel HA composite ... more details
For the word Can disambiguation Wiktionary CAN TOCright CAN may refer to Organizations Andean Community of Nations , a South American trade bloc with Bolivia, Colombia, Ecuador and Peru Campus Antiwar Network , an American network of students opposing the occupation of Iraq Capital Alumni Network , an American networking organization for alumni groups Chechnya Advocacy Network , an American non government organization for Chechnya advocacy Christian Association of Nigeria , an umbrella organization containing numerous Christian denominations in Nigeria Cure Autism Now , a former American organization for autism advocacy Climate Action Network , an international non governmental network to limit human induced climate change Cult Awareness Network , an American organization operated by the Church of Scientology Cycling Advocates Network , a New Zealand cycling advocacy group Corporate Angel Network , an American non profit organization that arranges free air travel for cancer patients Science and medicine Ceric ammonium nitrate , an inorganic compound Calcium ammonium nitrate , a fertilizer CAN gene , a human gene Chronic allograft nephropathy , a disease of transplanted tissue Consistent and asymptotically normal , a statistic estimator Computing Campus area network or corporate area network, a computer network in a limited geographical area Cancel character , a precision control character in the C0 control code set Content addressable network , type of P2P network Controller area network , a type of microcontroller bus Aviation Guangzhou Baiyun International Airport IATA airport code , the main airport in Guangzhou, Guangdong, China Crest Aviation ICAO airline designator , an airline in the United Kingdom Other ISO 3166 1 alpha 3 ISO country code for Canada disambig cs CAN da CAN de CAN es CAN eo CAN fr CAN ko CAN it CAN lt CAN nl CAN ja CAN pl CAN ujednoznacznienie ro CAN ru Can simple Can sv CAN ... more details
See also Biomedical material and Implant medicine Biomedical tissue is Tissue biology biological tissue used for organ transplant ation and medical research, particularly cancer research. Such tissues and organs may be referred to as implant tissue, allograft , xenograft , skin graft tissue, human transplant tissue, implant bone. Tissue is stored in tissue establishments or tissue banks under cryogenic conditions. Fluids such as blood, blood products and urine are stored in fluid banks under similar conditions. Regulation The collection, storage, analysis and transplantation of human tissue involves significant ethical and safety issues, and is heavily regulated. Each country sets its own framework for ensuring the safety of human tissue products. The regulation of human transplantation in the United Kingdom is set out in the Human Tissue Act 2004 and managed by the Human Tissue Authority . ref name HTA remit cite web author Human Tissue Authority authorlink Human Tissue Authority title Remit url http www.hta.gov.uk aboutus remit ref Tissue banks in the United States US are monitored by the Food and Drug Administration FDA . The Code of Federal Regulations sets out the following topics ref name CFR2003 cite web author Food and Drug Administration authorlink Food and Drug Administration title Part 1270 Human Tissue Intended for Transplantation year 2003 work Title 21 Food and Drugs publisher Code of Federal Regulations url http www.access.gpo.gov nara cfr waisidx 03 21cfr1270 03.html ref Donor Screening and Testing the determination of donor suitability for human tissue intended for transplantation. Procedures and Records the written procedures and records that must be kept Inspection of Tissue Establishments the importation of tissues from abroad and the retention, recall, and destruction of human tissue. Notable regulation cases Biomedical Tissue Services, Inc. is at the heart of an investigation by the Food and Drug Administration. http www.fda.gov bbs topics ... more details
distinguish photophoresis In medicine , photopheresis or extracorporeal photopheresis is a form of apheresis and photodynamic therapy in which blood is treated with photoactivable drugs which are then activated with ultraviolet light . Photopheresis is currently standard therapy approved by the Food and Drug Administration United States U.S. Food and Drug Administration FDA for cutaneous T cell lymphoma . In this procedure, buffy coat White blood cell WBC platelet s is separated from whole blood, chemically treated with 8 methoxypsoralen instilled into collection bag or given per os in advance , exposed to ultraviolet light, and returned to the patient. 8 Methoxypsoralen irreversibly binds covalently to both strands of the DNA of nucleated cells following photoactivation. The photochemically damaged T cell s returned to the patient appear to induce cytotoxic effects on T cell formation. The mechanism of such antitumor action has not been elucidated. Minimal observed adverse effect side effect s for patients receiving photopheresis include hypotension and Syncope medicine syncope resulting from volume shifts during leukapheresis phase of treatment. Photopheresis is also used as an experimental treatment in patients with cardiac, pulmonary and renal allograft rejection, graft versus host disease , autoimmune diseases , nephrogenic systemic fibrosis and ulcerative colitis . See also Blood irradiation therapy External links http www.apheresis.org American Society for Apheresis http www.cancer.gov Templates db alpha.aspx?CdrID 403135 Extracorporeal photopheresis entry in the public domain NCI Dictionary of Cancer Terms http www.emedicine.com derm topic566.htm Extracorporeal photopheresis definition at eMedicine.com http cutaneouslymphoma.stanford.edu community photopheresis.html Extracorporeal photopheresis discussion at Stanford School of Medicine Category Medical treatments Category Light therapy Category Blood de Photopherese pl Fotofereza medicine stub ... more details
BLP sources date December 2010 Beno t Lengel is a Physician doctor , anatomist and Belgian surgeon , born in Brussels . Early life Born in Brussels, Beno t Lengel studied medicine at the Catholic University of Leuven , graduating in 1987. ref name portrait cite web url http www.uclouvain.be 17293.html title Portrait minute Beno t Lengel , ma tre dans l art du portrait date 31 May 2006 publisher Catholic University of Leuven accessdate 30 December 3010 in French ref He was interested by face morphology and face modifications caused by aging. Work As the Chief Professor of the Chair of Human Anatomy at the Universit Catholique de Louvain Catholic University of Louvain , he is also head of the department of Experimental morphology biology Morphology . Citation needed date December 2010 Also a plastic surgeon, ref cite web url http www.saintluc.be consultation fiche.php?id 243 title Beno t Lengel publisher University of St. Luke Clinic accessdate 30 December 3010 ref in 1991 he worked in maxillo facial surgery of the Central University Hospital in Amiens , where he met Bernard Duchauvelle and Sylvie Testelin. With his colleagues, he developed several new techniques aimed at reconstructing by microsurgery, specific parts of the head and the neck, such as the larynx or the inferior lip. Together they came to the conclusion that results obtained by these autotransplants are imperfect and emit the idea that face allografts could be used to repair patients suffering from severe disfigurations . Citation needed date December 2010 On 26 November 2005, Beno t Lengel performed, with Bernard Dechauvelle and Sylvie Testelin in Amiens, the first partial face allograft to repair the mutilated face of Isabelle Dinoire , a young woman severely bitten by her dog. ref name portrait ref cite web url http www.healthcarebelgium.com index.php?id cusaint luc title World s first partial face transplant publisher Brussels Saint Luc University Hospital accessdate 30 December 2010 ref In 20 ... more details
Image Jacques Louis Reverdin 1842 1929.jpg right thumb Jacques Louis Reverdin Jacques Louis Reverdin August 28, 1842 January 9, 1929 was a Swiss surgeon who was a native of Cologny . He studied at the University of Paris , and in 1865 became an interne des h pitaux . He 1869 he became an assistant to Jean Casimir F lix Guyon 1831 1920 in the surgical department at the H pital Necker in Paris . Afterwards he moved to Geneva , where he eventually became chief surgeon at the H pital Cantonal de Geneve , and a professor at the University of Geneva . Reverdin is credited with performing the first fresh skin allograft , ref http books.google.com books?id POQB4YIjAnoC&pg PA180&lpg PA180&dq 22Jacques Louis Reverdin 22 allograft&source bl&ots w2auYaaW7E&sig TPqJ5TCrXW8n3efmRL 5hV j AY&hl en&ei yZ9SSvr3B47kNdXCweQI&sa X&oi book result&ct result&resnum 6 Organ transplantation by David Petechuk ref and in 1869 while working in Paris, introduced the pinch graft , which is a procedure for removing tiny pieces of skin from a healthy area of the body and seeding them in a location that needs to be covered. This procedure is sometimes referred to as a Reverdin graft . ref http www.mondofacto.com facts dictionary?pinch graft Mondofacto Dictionary definition of eponym ref His name is also associated with the Reverdin suture needle , which is a specialized surgical needle. In 1882, with his cousin and assistant Auguste Reverdin 1848 1908 , he observed that myxedema occurred as a delayed complication when the thyroid gland is surgically removed. He documented his findings in an article titled Note sur vingt deux op rations de goitre , and on September 13, 1882 presented his observations to the Medical Society of Geneva. References http www.artandmedicine.com biblio authors Reverdin.html Art and Medicine.com about Note sur vingt deux op rations de goitre http www.portfolio.mvm.ed.ac.uk studentwebs session5 37 CL otherhistory.htm History of Organ and Tissue Transplantation This article is ... more details
orphan date October 2009 Socket Preservation is a procedure in which graft material or scaffold is placed in the socket of an extracted tooth at the time of extraction to preserve the alveolar ridge. After extraction, jaw bones have to be preserved to keep sockets in its original shape. Without socket preservation, the bone quickly resorbs. The jaw bone will never revert to its original shape once bone is lost and tissue contour has changed. Socket Preservation differs from Ridge Augmentation in Socket Preservation, the graft or scaffold is placed inside the tooth socket immediately after extraction, whereas the Ridge Augmentation grafting procedure is done to bring back the lost bone after the bone has resorbed and there is insufficient ridge height or width for further treatment procedure. Benefits Socket Preservation procedure prevents immediate bone resorption after extraction thus keeping the contour and integrity of the socket with successful and natural looking appearance for tooth restorative procedures. All dental prosthesis requires good jaw bone support for it to be successful in the long run. Without socket preservation, residual bones could lose volume resulting in loss of facial vertical and horizontal dimension and changes in facial soft tissues aesthetics. Types of Materials that could be used for Socket Preservation Autograft Bone harvested from patient s own body. Xenograft Bone grafts or Collagen from bovine or porcine origin. Allograft Block bone graft from Cadaver . Alloplast Synthetic biomaterials such as PLGA , Hydroxapatite, Tricalcium Phosphate , Bioglass Ceramics etc. References Tassos Irinakis, Rationale for Socket Preservation after Extraction of a Single Rooted Tooth when Planning for Future Implant Placement, Journal of Canadian Dental Association 2006 72 10 917 922. http medical dictionary.thefreedictionary.com socket preservation http www.osseonews.com bone augmenation and ridge preservation FicklL Stefan Zuhr Otto WachtelL Hannes Sta ... more details
, R.E ., Cannon, P.J. Induction of myocardial nitric oxide synthase by cardiac allograft rejection ... ., Suciu Foca, N. Indirect recognition of donor HLA DR peptides in organ allograft rejection 1996 Journal ... of cardiac myocytes during cardiac allograft rejection Relation to induction of nitric oxide synthase ... more details
rejection AMR or cardiac allograft vasculopathy CAV . AlloMap has been commercially available ... RC title Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression ... data obtained during the Cardiac Allograft Rejection Gene Expression Observational CARGO Study. From ... more details
DIRECTED THERAPY IN.14.aspx alpha beta T Cell Receptor Directed Therapy in Rat Allograft Recipients ... may be more efficacious than anti CD3 antibody treatment, and its potential for prolonging allograft ... 01270 INDUCTION OF LONG TERM RAT RENAL ALLOGRAFT.32.aspx Induction of Long Term Renal Allograft Survival ..., S., et al http journals.lww.com transplantjournal Abstract 1999 02270 Suppression of Allograft Rejection With Anti T.19.aspx Suppression of Allograft Rejection with Anti T Cell Receptor Antibody ... more details
a cadaver and used as an allograft in reconstruction. The Achilles tendon, due to its large size ... be cause to remove the graft. Therefore, the option to use an irradiated allograft runs the largest ... joint stiffness. An allograft is a graft from a corpse, usually either a patellar tendon, hamstring tendon, and occasionally an achilles tendon. The advantage of an allograft is the patient does not sustain ... more details
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