Unreferenced stub auto yes date December 2009 Chembox verifiedrevid 384066647 ImageFile Uridindiphosphat protoniert.svg ImageSize IUPACName Uridine 5 trihydrogen diphosphate OtherNames Section1 Chembox Identifiers CASNo 58 98 0 CASNo Ref cascite PubChem 1158 IUPHAR ligand 1749 SMILES MeSHName Uridine diphosphate Section2 Chembox Properties Formula C sub 9 sub H sub 14 sub N sub 2 sub O sub 12 sub P sub 2 sub MolarMass 404.161 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine diphosphate , abbreviated UDP , is a nucleotide . It is an ester of pyrophosphoric acid with the nucleoside uridine . UDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase uracil . See also Nucleoside Nucleotide DNA RNA Oligonucleotide UGGT Nucleobases, nucleosides, and nucleotides DEFAULTSORT Uridine Diphosphate Category Nucleotides Category Pyrimidinediones Biochem stub ca Difosfat d uridina da Uridindifosfat de Uridindiphosphat es Uridina difosfato nl Uridinedifosfaat ja pl Urydynodifosforan sr Uridin difosfat fi Uridiinidifosfaatti zh ... more details
chembox verifiedrevid 402840143 ImageFile UDP Galactose.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers InChI 1 C9H12N2O6.C6H14O12P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 3 9 5 10 6 18 20 14,15 16 4 2 8 17 19 11,12 13 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 2 7,9 10H,1H2, H2,11,12,13 H2,14,15,16 p 4 t4 ,6 ,7 ,8 3 ,4 ,5 ,6 m11 s1 InChIKey UYLAOKYVSPTOGT HUYLZDLQBS StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H12N2O6.C6H14O12P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 3 9 5 10 6 18 20 14,15 16 4 2 8 17 19 11,12 13 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 2 7,9 10H,1H2, H2,11,12,13 H2,14,15,16 p 4 t4 ,6 ,7 ,8 3 ,4 ,5 ,6 m11 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey UYLAOKYVSPTOGT UESRDHDISA J CASNo 2956 16 3 PubChem 1166 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 19951534 SMILES OC C H O C H O C H OP O O O C H C O OP O O O.O C 1NC O N C C 1 C H 2O C H CO C H O C H 2O MeSHName Uridine diphosphate galactose Section2 Chembox Properties Formula C sub 15 sub H sub 24 sub N sub 2 sub O sub 17 sub P sub 2 sub MolarMass 566.302 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine diphosphate galactose Uridine diphosphate UDP galactose is an intermediate in the production of polysaccharide s. It is important in nucleotide sugars metabolism , and is the substrate for the transferase B4GALT5 . See also UDP galactose epimerase uridine diphosphate galactose Category Coenzymes Category Nucleotides biochem stub Fructose and galactose metabolic intermediates ja ... more details
DISPLAYTITLE Uridinediphosphate N acetylglucosamine Chembox Name Uridinediphosphate N acetylglucosamine ImageFile UDP N acetylglucosamine.png ImageSize 200px IUPACName 2 R ,3 R ,4 R ,5 S ,6 R 3 acetamido 4,5 dihydroxy 6 hydroxymethyl oxan 2 yl nowiki nowiki 2 R ,3 S ,4 R ,5 R 5 2,4 dioxopyrimidin 1 yl 3,4 dihydroxyoxolan 2 yl methoxy hydroxyphosphoryl hydrogen phosphate OtherNames UDP N acetylglucosamine UDP GlcNAc Section1 Chembox Identifiers CASNo 7277 98 7 PubChem 445675 SMILES CC O N C H 1 C H C H C H O C H 1OP O O OP O O OC C H 2 C H C H C H O2 N3C CC O NC3 O O O CO O O Section2 Chembox Properties C 17 H 27 N 3 O 17 P 2 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridinediphosphate N acetylglucosamine or UDP GlcNAc is a nucleotide sugar and a coenzyme in metabolism . It is used by glycosyltransferase s to transfer N Acetylglucosamine N acetylglucosamine residues to substrates. small D small Glucosamine is made naturally in the form of glucosamine 6 phosphate, and is the biochemical precursor of all amino sugar nitrogen containing sugars . ref cite journal doi 10.1074 jbc.R100053200 last1 Roseman first1 S title Reflections on glycobiology url http www.jbc.org cgi content full 276 45 41527 journal The Journal of biological chemistry volume 276 issue 45 pages 41527 42 year 2001 pmid 11553646 ref To be specific, glucosamine 6 phosphate is synthesized from fructose 6 phosphate and glutamine ref cite journal author1 Sudhamoy Ghosh last2 Blumenthal first2 HJ last3 Davidson first3 E last4 Roseman first4 S title Glucosamine Metabolism url http www.jbc.org cgi reprint 235 5 1265 journal Journal of Biological Chemistry volume 235 issue 5 pages 1265 date 1960 05 01 pmid 13827775 ref as the first step of the hexosamine biosynthesis pathway. ref http www.chem.qmul.ac.uk iubmb enzyme reaction polysacc UDPGlcN.html International Union of Biochemistry and Molecular Biology ref The end product of this pathway is UDP ... more details
chembox verifiedrevid 402840353 ImageFile UDP glucuronic acid.png ImageSize 200px IUPACName OtherNames Section1 Chembox Identifiers InChI 1 C9H12N2O6.C6H12O13P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 2 18 20 12,13 14 5 19 21 15,16 17 3 8 4 9 6 10 11 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 1 5,8 9H, H,10,11 H2,12,13,14 H2,15,16,17 p 4 t4 ,6 ,7 ,8 2 ,3 ,4 ,5 m10 s1 InChIKey GIFKDHYZEJQSDD DNQFPBLIBB StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H12N2O6.C6H12O13P2 c12 3 4 6 14 7 15 8 17 4 11 2 1 5 13 10 9 11 16 7 1 2 18 20 12,13 14 5 19 21 15,16 17 3 8 4 9 6 10 11 h1 2,4,6 8,12,14 15H,3H2, H,10,13,16 1 5,8 9H, H,10,11 H2,12,13,14 H2,15,16,17 p 4 t4 ,6 ,7 ,8 2 ,3 ,4 ,5 m10 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey GIFKDHYZEJQSDD BZYIUNRFSA J CASNo 2616 64 0 PubChem 17473 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 19951236 IUPHAR ligand 1784 SMILES OC O C H O C H O C H OP O O O C H C O OP O O O.O C 1NC O N C C 1 C H 2O C H CO C H O C H 2O MeSHName UDP glucuronic acid Section2 Chembox Properties Formula C sub 15 sub H sub 22 sub N sub 2 sub O sub 18 sub P sub 2 sub MolarMass 580.285 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition UDP glucuronic acid is a sugar used in the creation of polysaccharide s and is an intermediate in the biosynthesis of ascorbic acid except in primate s and guinea pig s . It is made from UDP glucose by UDP glucose 6 dehydrogenase EC 1.1.1.22 using NAD as a cofactor. It is the source of the glucuronosyl group in glucuronosyltransferase reactions. See also glucuronic acid Uridine diphosphate UDP Nucleotide sugars Category Organophosphates Category Glycosides Category Coenzymes Category Nucleotides biochem stub ja fi UDP glukuronihappo ... more details
chembox verifiedrevid 407587952 ImageFile Uridin.svg ImageSize 150px IUPACName uridine OtherNames Section1 Chembox Identifiers CASNo 58 96 8 CASNo Ref cascite correct CAS PubChem SMILES O C1NC O N C C1 C H 2O C H CO C H O C H 2O MeSHName Uridine Section2 Chembox Properties C 9 H 12 N 2 O 6 MolarMass 244.20 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Uridine is a molecule known as a nucleoside that is formed when uracil is attached to a ribose ring also known as a ribofuranose via a N sub 1 sub glycosidic bond . If uracil is attached to a deoxyribose ring, it is known as a deoxyuridine . Dietary sources of uridineUridine is one of the four basic components of ribonucleic acid RNA the other three are adenosine , guanosine , and cytidine . Upon digestion of foods containing RNA, uridine is released from RNA and is absorbed intact in the gut. Some common food sources of uridine are Sugarcane extract ref http www.thebody.com content art30244.html Thebody.com ref Tomatoes 0.5 to 1.0 g uridine per kilogram dry weight ref http www.aseanfood.info Articles 11018411.pdf Aseanfood.info ref Brewer s yeast 3 uridine by dry weight ... Z, Ka T, Fukuchi M, Hada T title Effect of beer on the plasma concentrations of uridine and purine bases ... provide adequate uridine for improved health with minimal side effects. Citation needed date ... in rats with a combination of uridine and EPA DHA omega 3 fatty acids has antidepressant ... BM, Renshaw PF title Antidepressant like effects of uridine and omega 3 fatty acids are potentiated ... February pmid 15705349 doi 10.1016 j.biopsych.2004.11.038 url ref Uridine in the Glycolysis Pathway Uridine plays a role in the glycolysis pathway of galactose . ref http www.ncbi.nlm.nih.gov bookshelf ... in a reaction with UDP glucose, a glucose molecule bonded to a UDP uridine di phosphate molecule ... Uridine it Uridina lt Uridinas nl Uridine ja oc Uridina pl Urydyna pt Uridina sr Uridin sv Uridin ... more details
enzyme Name uridine kinase EC number 2.7.1.48 CAS number 9026 39 5 IUBMB EC number 2 7 1 48 GO code 0004849 image width caption In enzymology , an uridine kinase EC number 2.7.1.48 is an enzyme that catalysis catalyzes the chemical reaction ATP uridine math rightleftharpoons math ADP UMP Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and uridine , whereas its two product chemistry products are adenosine diphosphate ADP and uridine monophosphate UMP . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP uridine 5 phosphotransferase . Other names in common use include pyrimidine ribonucleoside kinase , uridine cytidine kinase , uridine kinase phosphorylating , and uridine phosphokinase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, 8 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1UDW , PDB link 1UEI , PDB link 1UEJ , PDB link 1UFQ , PDB link 1UJ2 , PDB link 1XRJ , PDB link 2JEO , and PDB link 2UVQ . References reflist 1 cite journal author Orengo A date 1969 title Regulation of enzymic activity by metabolites. I. Uridine cytidine kinase of Novikoff ascites rat tumor journal J. Biol. Chem. volume 244 pages 2204&ndash 9 pmid 5782006 issue 8 cite journal author Skold O date 1960 title Uridine kinase from Erlich ascites tumor purification and properties journal J. Biol. Chem. volume 235 pages 3273&ndash 3279 enzyme stub Category EC 2.7.1 Category Enzymes of known structure ... more details
fed supplements of uridine monophosphate, choline, and docosahexaenoic acid DHA were found to have ... ref Uridine Monophosphate in Foods In brain research studies such as those mentioned in this article, uridine monophosphate is used as a convenient delivery compound for uridine . Uridine is the active ingredient of the compound. A common misconception is that uridine and its compounds are not available ... drugs. This is not so. Uridine monophosphate is a major component of RNA . Any food rich in RNA ... information, consult the article on uridine . References reflist See also Nucleoside Nucleotide DNA ... biochem stub ca Monofosfat d uridina da Uridinmonofosfat de Uridinmonophosphat fr Uridine monophosphate ... more details
enzyme Name uridine nucleosidase EC number 3.2.2.3 CAS number 9025 47 2 IUBMB EC number 3 2 2 3 GO code 0045437 image width caption In enzymology , an uridine nucleosidase EC number 3.2.2.3 is an enzyme that catalysis catalyzes the chemical reaction uridine H sub 2 sub O math rightleftharpoons math D ribose uracil Thus, the two substrate biochemistry substrates of this enzyme are uridine and water H sub 2 sub O , whereas its two product chemistry products are D ribose and uracil . This enzyme belongs to the family of hydrolase s, specifically those glycosylases that hydrolyse N glycosyl compounds. The systematic name of this enzyme class is uridine ribohydrolase . This enzyme is also called uridine hydrolase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, 23 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1EMH , PDB link 1EMJ , PDB link 1EUG , PDB link 1FLZ , PDB link 1OKB , PDB link 1SSP , PDB link 1UDG , PDB link 1UDH , PDB link 1UDI , PDB link 1UGH , PDB link 1UUG , PDB link 1YUO , PDB link 2BOO , PDB link 2C53 , PDB link 2C56 , PDB link 2EUG , PDB link 2J8X , PDB link 2SSP , PDB link 2UUG , PDB link 3EUG , PDB link 4EUG , PDB link 4SKN , and PDB link 5EUG . References reflist 1 cite journal author Carter CE date 1951 title Partial purification of a non phosphorylytic uridine nucleosidase from yeast journal J. Am. Chem. Soc. volume 73 pages 1508&ndash 1510 doi 10.1021 ja01148a028 hydrolase stub Category EC 3.2.2 Category Enzymes of known structure ... more details
enzyme Name uridine phosphorylase EC number 2.4.2.3 CAS number 9030 22 2 IUBMB EC number 2 4 2 3 GO code 0004850 image width caption In enzymology , an uridine phosphorylase EC number 2.4.2.3 is an enzyme that catalysis catalyzes the chemical reaction uridine phosphate math rightleftharpoons math uracil alpha D ribose 1 phosphate Thus, the two substrate biochemistry substrates of this enzyme are uridine and phosphate , whereas its two product chemistry products are uracil and alpha D ribose 1 phosphate . This enzyme belongs to the family of glycosyltransferase s, specifically the pentosyltransferases. The systematic name of this enzyme class is uridine phosphate alpha D ribosyltransferase . Other names in common use include pyrimidine phosphorylase , UrdPase , UPH , and UPase . This enzyme participates in pyrimidine metabolism . Structural studies As of late 2007, 27 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1K3F , PDB link 1LX7 , PDB link 1RXC , PDB link 1RXS , PDB link 1RXU , PDB link 1RXY , PDB link 1RYZ , PDB link 1SJ9 , PDB link 1SQ6 , PDB link 1T0U , PDB link 1TGV , PDB link 1TGY , PDB link 1U1C , PDB link 1U1D , PDB link 1U1E , PDB link 1U1F , PDB link 1U1G , PDB link 1Y1Q , PDB link 1Y1R , PDB link 1Y1S , PDB link 1Y1T , PDB link 1ZL2 , PDB link 2HN9 , PDB link 2HRD , PDB link 2HSW , PDB link 2HWU , and PDB link 2I8A . References reflist 1 cite journal author CANELLAKIS ES date 1957 title Pyrimidine metabolism. II. Enzymatic pathways of uracil anabolism journal J. Biol. Chem. volume 227 pages 329&ndash 38 pmid 13449076 issue 1 cite journal author PAEGE LM, SCHLENK F date 1952 title Bacterial uracil riboside phosphorylase journal Arch. Biochem. Biophys. volume 40 pages 42&ndash 9 pmid 12997187 doi 10.1016 0003 9861 52 90071 4 issue 1 cite journal author Pontis H, Degerstedt G and Reichard P date 1961 title Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor journal ... more details
Unreferenced stub auto yes date December 2009 Chembox verifiedrevid 413100674 ImageFile Uridintriphosphat2.svg ImageSize IUPACName 2R,3S,4R,5R 5 2,4 dioxopyrimidin 1 yl 3,4 dihydroxyoxolan 2 yl methyl hydroxy phosphonooxyphosphoryl hydrogen phosphate OtherNames Section1 Chembox Identifiers CASNo 63 39 8 CASNo Ref cascite PubChem 1181 SMILES MeSHName Uridine triphosphate Section2 Chembox Properties Formula C sub 9 sub H sub 15 sub N sub 2 sub O sub 15 sub P sub 3 sub MolarMass 484.141 Appearance Density MeltingPt BoilingPt Section3 Chembox Hazards Solubility MainHazards FlashPt Autoignition Uridine 5 triphosphate UTP is a pyrimidine nucleotide , consisting of the organic base uracil linked to the 1 carbon of the ribose sugar, and esterified with tri phosphoric acid at the 5 position. Its main role is as substrate for the synthesis of RNA during transcription genetics transcription . Role in metabolism UTP also has the role of a source of energy or an activator of substrates in metabolic reactions, like that of Adenosine Triphosphate ATP , but more specific. When UTP activates a substrate, UDP substrate is usually formed and inorganic phosphate is released. UDP glucose enters the synthesis of glycogen . UTP is used in the metabolism of galactose , where the activated form UDP galactose is converted to UDP glucose. UDP glucuronate is used to conjugate bilirubin to a more water soluble bilirubin diglucuronide . See also CTP synthase Nucleobases, nucleosides, and nucleotides DEFAULTSORT Uridine Triphosphate Category Nucleotides Category Gene expression Category Metabolism Category Pyrimidinediones Biochem stub ca Trifosfat d uridina cs Uridintrifosf t da Uridintrifosfat de Uridintriphosphat es Uridina trifosfato fr Uridine triphosphate it Uridintrifosfato nl Uridinetrifosfaat ja sr Uridin trifosfat zh ... more details
Unreferenced date October 2006 Chembox verifiedrevid 413260782 ImageFile 2 Desoxycytidindiphosphat.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo 800 73 7 PubChem 3972 SMILES Nc1ccn C2CC O C COP O O OP O O O O2 c O n1 MeSHName deoxycytidine diphosphate Section2 Chembox Properties Formula C sub 9 sub H sub 15 sub N sub 3 sub O sub 10 sub P sub 2 sub MolarMass 387.177 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxycytidine diphosphate is a derivative of the common nucleic acid , cytidine triphosphate or CTP , in which the hydroxyl or OH group on the 2nd carbon of the nucleotide s pentose has been removed hence the deoxy part of the name. The diphosphate of the name indicates that one of the phosphorus phosphoryl groups of CTP has been removed, most likely by hydrolysis . Deoxyguanosine diphosphate would be abbreviated dCDP. See also DNA Cofactor biochemistry Cofactor Cytosine Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxycytidine Diphosphate Category Nucleotides Biochem stub ca Difosfat de desoxicitidina nl Deoxycytidinedifosfaat sr Dezoksicitidin difosfat zh ... more details
Unreferenced date December 2009 Chembox verifiedrevid 413260803 ImageFile DGDP chemical structure.png ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo PubChem 644 SMILES C1C C OC1N2C NC3 C2NC NC3 O N COP O O OP O O O O Section2 Chembox Properties Formula C sub 10 sub H sub 15 sub N sub 5 sub O sub 10 sub P sub 2 sub MolarMass 427.201122 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyguanosine diphosphate is a derivative of the common nucleic acid GTP, or guanosine triphosphate , in which the OH hydroxyl group on the 2 carbon on the nucleotide s pentose has been removed hence the deoxy part of the name . The diphosphate of the name indicates that one of the phosphate phosphoryl groups of GTP has been removed, most likely by hydrolysis . Deoxyguanosine diphosphate is abbreviated dGDP. See also Nucleic acid DNA metabolism Cofactor biochemistry Cofactor Guanosine Nucleobases, nucleosides, and nucleotides DEFAULTSORT Deoxyguanosine Diphosphate Category Nucleotides ca Difosfat de desoxiguanosina nl Deoxyguanosinedifosfaat sr Dezoksiguanozin difosfat zh ... more details
chembox verifiedrevid 413258262 ImageFile DADP chemical structure.png ImageSize IUPACName nowiki 5 6 aminopurin 9 yl 3 hydroxyoxolan 2 yl methyl phosphono hydrogen nowiki OtherNames dADP Reference ref http pubchem.ncbi.nlm.nih.gov summary summary.cgi?cid 620 dADP Compound Summary , PubChem . ref Section1 Chembox Identifiers CASNo 2793 06 8 PubChem 620 MeSHName Deoxyadenosine diphosphate SMILES C1C C OC1N2C NC3 C2N CN C3N COP O O OP O O O O Section2 Chembox Properties Formula C sub 10 sub H sub 15 sub N sub 5 sub O sub 9 sub P sub 2 sub MolarMass 411.201722 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxyadenosine diphosphate is a derivative of the common nucleic acid ATP, or adenosine triphosphate , in which the OH hydroxyl group on the 2 carbon on the nucleotide s pentose has been removed hence the deoxy part of the name . Additionally, the diphosphate of the name indicates that one of the phosphoryl groups of ATP has been removed, most likely by hydrolysis . Deoxyadenosine diphosphate would be abbreviated dADP. See also Cofactor biochemistry Cofactor Guanosine Cyclic adenosine monophosphate References reflist Nucleobases, nucleosides, and nucleotides Category Nucleotides ca Difosfat de desoxiadenosina nl Deoxyadenosinedifosfaat sr Dezoksiadenozin difosfat zh ... more details
chembox ImageFile dTDP chemical structure.png ImageSize 197 IUPACName 2R,3S,5R 3 hydroxy br 5 5 methyl 2,4 dioxopyrimidin br 1 yl oxolan 2 yl methyl phosphono hydrogen phosphate OtherNames Section1 Chembox Identifiers CASNo 1861 44 5 PubChem 164628 SMILES CC1 CN C O NC1 O C H 2C C H C H O2 COP O O OP O O O O MeSHName Section2 Chembox Properties Formula C sub 10 sub H sub 16 sub N sub 2 sub O sub 12 sub P sub 2 sub MolarMass 402.19 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Deoxythymidine diphosphate , abbreviated TDP , is a nucleotide . It is an ester of pyrophosphoric acid with the nucleoside thymidine . TDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase thymine . clear See also Nucleoside Nucleotide DNA RNA Oligonucleotide Thymidine diphosphate glucose dTDP glucose External links Nucleobases, nucleosides, and nucleotides Category Nucleotides biochem stub ca Difosfat de timidina nl Thymidinedifosfaat ja sr Timidin difosfat zh ... more details
chembox verifiedrevid 413111496 ImageFile GDP chemical structure.png ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo 146 91 8 PubChem 730 IUPHAR ligand 2410 SMILES C1 NC2 C N1C3C C C O3 COP O O OP O O O O O NC NC2 O N Section2 Chembox Properties Formula C sub 10 sub H sub 15 sub N sub 5 sub O sub 11 sub P sub 2 sub MolarMass 443.200522 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Guanosine diphosphate , abbreviated GDP , is a nucleotide . It is an ester of pyrophosphoric acid with the nucleoside guanosine . GDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase guanine . GDP is the product of guanosine triphosphate GTP dephosphorylation by GTPase s, e.g., the G protein s that are involved in signal transduction . GDP is converted into GTP with the help of pyruvate kinase and phosphoenolpyruvate. See also Nucleoside Nucleotide DNA RNA Oligonucleotide Guanosine triphosphate Nucleobases, nucleosides, and nucleotides biochem stub Category Nucleotides Category Purines cs Guanosindifosf t da Guanosindifosfat de Guanosindiphosphat es Guanos n difosfato fr Guanosine diphosphate it Guanosindifosfato nl Guanosinedifosfaat ja oc Guanosina difosfat pl Guanozynodifosforan pt Guanosina difosfato ru sr Guanozin difosfat fi Guanosiinidifosfaatti sv Guanosindifosfat zh ... more details
diphosphate ga D fhosf it adan is n ko hr Adenozin difosfat id Adenosina difosfat it Adenosina ... Adenosine diphosphate sr sh Adenozin difosfat fi Adenosiinidifosfaatti sv Adenosindifosfat tr Adenozin difosfat uk ur Adenosine diphosphate vi Adenosine diphosphate ... more details
chembox verifiedrevid 414402383 ImageFile Cytidindiphosphat protoniert.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 5902 InChI 1 C9H15N3O11P2 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 22 8 3 21 25 19,20 23 24 16,17 18 h1 2,4,6 8,13 14H,3H2, H,19,20 H2,10,11,15 H2,16,17,18 t4 ,6 ,7 ,8 m1 s1 InChIKey ZWIADYZPOWUWEW XVFCMESIBF ChEMBL Ref ebicite correct EBI ChEMBL 425252 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C9H15N3O11P2 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 22 8 3 21 25 19,20 23 24 16,17 18 h1 2,4,6 8,13 14H,3H2, H,19,20 H2,10,11,15 H2,16,17,18 t4 ,6 ,7 ,8 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey ZWIADYZPOWUWEW XVFCMESISA N CASNo 63 38 7 CASNo Ref cascite correct CAS CASOther br 34393 59 4 disodium salt NOT CAS verified PubChem 290 SMILES O P O O OP O O OC C H 2O C H N 1C O N C N C C 1 C H O C H 2O Section2 Chembox Properties Formula C sub 9 sub H sub 15 sub N sub 3 sub O sub 11 sub P sub 2 sub MolarMass 403.176422 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cytidine diphosphate , abbreviated CDP , is a nucleotide . It is an ester of pyrophosphoric acid with the nucleoside cytidine . CDP consists of the pyrophosphate Functional group group , the pentose sugar ribose , and the nucleobase cytosine . See also Nucleoside Nucleotide DNA RNA Oligonucleotide External links Nucleobases, nucleosides, and nucleotides Category Nucleotides Category Pyrimidones biochem stub ca Difosfat de citidina da Cytidindifosfat de Cytidindiphosphat it Citosindifosfato nl Cytidinedifosfaat ja sr Citidin difosfat zh ... more details
chembox verifiedrevid 400861676 ImageFile Prephytoene diphosphate.png ImageSize 250px IUPACName 1 R ,2 R ,3 R 2 methyl 3 1 E ,5 E ,9 E 2,6,10,14 tetramethylpentadeca 1,5,9,13 tetraenyl 2 3 E ,7 E 4,8,12 trimethyltrideca 3,7,11 trienyl cyclopropyl methyl phosphono hydrogen phosphate OtherNames Prephytoene pyrophosphate Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 4517882 InChI 1 C40H68O7P2 c1 31 2 17 11 19 33 5 21 13 23 35 7 25 15 26 37 9 29 38 39 30 46 49 44,45 47 48 41,42 43 40 38,10 28 16 27 36 8 24 14 22 34 6 20 12 18 32 3 4 h17 18,21 22,25,27,29,38 39H,11 16,19 20,23 24,26,28,30H2,1 10H3, H,44,45 H2,41,42,43 b33 21 ,34 22 ,35 25 ,36 27 ,37 29 InChIKey RVCNKTPCHZNAAO QKUGLALCBM StdInChI Ref stdinchicite correct chemspider StdInChI 1S C40H68O7P2 c1 31 2 17 11 19 33 5 21 13 23 35 7 25 15 26 37 9 29 38 39 30 46 49 44,45 47 48 41,42 43 40 38,10 28 16 27 36 8 24 14 22 34 6 20 12 18 32 3 4 h17 18,21 22,25,27,29,38 39H,11 16,19 20,23 24,26,28,30H2,1 10H3, H,44,45 H2,41,42,43 b33 21 ,34 22 ,35 25 ,36 27 ,37 29 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey RVCNKTPCHZNAAO QKUGLALCSA N CASNo 38005 61 7 PubChem 5365949 SMILES O P O O OP O O OCC1C C C C CC C C C CC C C C CC C C C C C1 CC C C CC C C C CC C C C C C C Section2 Chembox Properties Formula C sub 40 sub H sub 68 sub O sub 7 sub P sub 2 sub MolarMass 722.91 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Prephytoene diphosphate is a carotenoid precursor. organic compound stub Cholesterol and steroid intermediates Category Carotenoids Category Organophosphates Category Cyclopropanes ... more details
enzyme Name tRNA uridine aminocarboxypropyltransferase EC number 2.5.1.25 CAS number IUBMB EC number 2 5 1 25 GO code 0016432 image width caption lowercase In enzymology , a tRNA uridine aminocarboxypropyltransferase EC number 2.5.1.25 is an enzyme that catalysis catalyzes the chemical reaction S adenosyl L methionine tRNA uridine math rightleftharpoons math 5 methylthioadenosine tRNA 3 3 amino 3 carboxypropyl uridine Thus, the two substrate biochemistry substrates of this enzyme are S adenosyl L methionine and tRNA uridine , whereas its two product chemistry products are 5 methylthioadenosine and tRNA 3 3 amino 3 carboxypropyl uridine . This enzyme belongs to the family of transferase s, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S adenosyl L methionine tRNA uridine 3 3 amino 3 carboxypropyl transferase . References reflist 1 cite journal author Nishimura S, Taya Y, Kuchino Y, Oashi Z date 1974 title Enzymatic synthesis of 3 3 amino 3 carboxypropyl uridine in Escherichia coli phenylalanine transfer RNA transfer of the 3 amino acid 3 carboxypropyl group from S adenosylmethionine journal Biochem. Biophys. Res. Commun. volume 57 pages 702&ndash 8 pmid 4597321 issue 3 transferase stub Category EC 2.5.1 Category Enzymes of unknown structure ... more details
PBB geneid 7372 Uridine monophosphate synthetase UMPS orotate phosphoribosyl transferase and orotidine 5 decarboxylase is the enzyme EC number 4.1.1.23 that catalyses the formation of uridine monophosphate UMP , an energy carrying molecule in many important biosynthetic pathways. ref name entrez cite web title Entrez Gene UMPS uridine monophosphate synthetase orotate phosphoribosyl transferase and orotidine 5 decarboxylase url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 7372 accessdate ref In humans, the gene that codes for this enzyme is located on the long arm of chromosome 3 3q13 . ref name pmid2767686 cite journal author Qumsiyeh MB, Valentine MB, Suttle DP title Localization of the gene for uridine monophosphate synthase to human chromosome region 3q13 by in situ hybridization journal Genomics volume 5 issue 1 pages 160 2 year 1989 month July pmid 2767686 doi 10.1016 0888 7543 89 90103 1 url ref Clinical significance A UMP synthetase deficiency can result in a metabolic disorder called orotic aciduria . ref name pmid9042911 cite journal author Suchi M, Mizuno H, Kawai Y, Tsuboi T, Sumi S, Okajima K, Hodgson ME, Ogawa H, Wada Y title Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families journal Am. J. Hum. Genet. volume 60 issue 3 pages 525 39 year 1997 month March ... author Shanks RD, Robinson JL title Embryonic mortality attributed to inherited deficiency of uridine ... WP1601 highlight Uridine monophosphate synthetase See also orotidine 5 phosphate decarboxylase ... doi cite journal author Qumsiyeh MB, Valentine MB, Suttle DP title Localization of the gene for uridine ... and initial characterization of the single polypeptide that synthesizes uridine 5 monophosphate from orotate in Ehrlich ascites carcinoma. Purification by tandem affinity chromatography of uridine ... of uridine monophosphate synthase UMPS gene to river buffalo chromosomes by FISH journal Chromosome ... more details
enzyme Name Z farnesyl diphosphate synthase EC number 2.5.1.68 CAS number IUBMB EC number 2 5 1 68 GO code image width caption In enzymology , a Z farnesyl diphosphate synthase EC number 2.5.1.68 is an enzyme that catalysis catalyzes the chemical reaction geranyl diphosphate isopentenyl diphosphate math rightleftharpoons math diphosphate 2Z,6E farnesyl diphosphate Thus, the two substrate biochemistry substrates of this enzyme are geranyl diphosphate and isopentenyl diphosphate , whereas its two product chemistry products are diphosphate and 2Z,6E farnesyl diphosphate . This enzyme belongs to the family of transferase s, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is geranyl diphosphate isopentenyl diphosphate geranylcistransferase . This enzyme is also called Z farnesyl diphosphate synthase . References reflist 1 cite journal author F, Bertini S, Brennan PJ, Crick DC date 2001 title Purification, enzymatic characterization, and inhibition of the Z farnesyl diphosphate synthase from Mycobacterium tuberculosis journal J. Biol. Chem. volume 276 pages 11624&ndash 30 pmid 11152452 doi 10.1074 jbc.M007168200 issue 15 transferase stub Category EC 2.5.1 Category Enzymes of unknown structure ... more details
enzyme Name Chrysanthemyl diphosphate synthase EC number 2.5.1.67 CAS number IUBMB EC number 2 5 1 67 GO code image width caption Orphan date February 2009 In enzymology , a chrysanthemyl diphosphate synthase EC number 2.5.1.67 is an enzyme that catalysis catalyzes the chemical reaction 2 dimethylallyl diphosphate math rightleftharpoons math diphosphate chrysanthemyl diphosphate Hence, this enzyme has one substrate biochemistry substrate , dimethylallyl diphosphate , and two product chemistry products , diphosphate and chrysanthemyl diphosphate . This enzyme belongs to the family of transferase s, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl diphosphate dimethylallyl diphosphate dimethylallyltransferase chrysanthemyl diphosphate forming . This enzyme is also called CPPase . References reflist 1 cite journal author Shattuck Eidens DM, Wrobel WM, Peiser GD, Poulter CD date 2001 title Chrysanthemyl diphosphate synthase isolation of the gene and characterization of the recombinant non head to tail monoterpene synthase from Chrysanthemum cinerariaefolium journal Proc. Natl. Acad. Sci. U. S. A. volume 98 pages 4373&ndash 8 pmid 11287653 doi 10.1073 pnas.071543598 issue 8 pmc 31842 cite journal author Erickson HK, Poulter CD date 2003 title Chrysanthemyl diphosphate synthase. The relationship among chain elongation, branching, and cyclopropanation reactions in the isoprenoid biosynthetic pathway journal J. Am. Chem. Soc. volume 125 pages 6886&ndash 8 pmid 12783539 doi 10.1021 ja034520g issue 23 transferase stub Category EC 2.5.1 Category Enzymes of unknown structure ... more details
enzyme Name Lavandulyl diphosphate synthase EC number 2.5.1.69 CAS number IUBMB EC number 2 5 1 69 GO code image width caption Orphan date February 2009 In enzymology , a lavandulyl diphosphate synthase EC number 2.5.1.69 is an enzyme that catalysis catalyzes the chemical reaction 2 dimethylallyl diphosphate math rightleftharpoons math diphosphate lavandulyl diphosphate Hence, this enzyme has one substrate biochemistry substrate , dimethylallyl diphosphate , and two product chemistry products , diphosphate and lavandulyl diphosphate . This enzyme belongs to the family of transferase s, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl diphosphate dimethylallyl diphosphate dimethylallyltransferase lavandulyl diphosphate forming . This enzyme is also called FDS 5 . References reflist 1 cite journal author Erickson HK, Poulter CD date 2003 title Chrysanthemyl diphosphate synthase. The relationship among chain elongation, branching, and cyclopropanation reactions in the isoprenoid biosynthetic pathway journal J. Am. Chem. Soc. volume 125 pages 6886&ndash 8 pmid 12783539 doi 10.1021 ja034520g issue 23 cite journal author Hemmerlin A, Rivera SB, Erickson HK, Poulter CD date 2003 title Enzymes encoded by the farnesyl diphosphate synthase gene family in the Big Sagebrush Artemisia tridentata ssp. spiciformis journal J. Biol. Chem. volume 278 pages 32132&ndash 40 pmid 12782626 doi 10.1074 jbc.M213045200 issue 34 transferase stub Category EC 2.5.1 Category Enzymes of unknown structure ... more details
enzyme Name guanosine 5 triphosphate,3 diphosphate diphosphatase EC number 3.6.1.40 CAS number 85130 44 5 IUBMB EC number 3 6 1 40 GO code 0008894 image width caption In enzymology , a guanosine 5 triphosphate,3 diphosphate diphosphatase EC number 3.6.1.40 is an enzyme that catalysis catalyzes the chemical reaction guanosine 5 triphosphate,3 diphosphate H sub 2 sub O math rightleftharpoons math guanosine 5 diphosphate,3 diphosphate phosphate Thus, the two substrate biochemistry substrates of this enzyme are guanosine 5 triphosphate,3 diphosphate and water H sub 2 sub O , whereas its two product chemistry products are guanosine 5 diphosphate,3 diphosphate and phosphate . This enzyme belongs to the family of hydrolase s, specifically those acting on acid anhydrides in phosphorus containing anhydrides. The systematic name of this enzyme class is guanosine 5 triphosphate,3 diphosphate 5 phosphohydrolase . Other names in common use include pppGpp 5 phosphohydrolase , guanosine 5 triphosphate,3 diphosphate pyrophosphatase , guanosine 5 triphosphate 3 diphosphate 5 phosphohydrolase , guanosine pentaphosphatase , guanosine pentaphosphate phosphatase , guanosine 5 triphosphate 3 diphosphate 5 phosphatase , and guanosine pentaphosphate phosphohydrolase . This enzyme participates in purine metabolism . Structural studies As of late 2007, two tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1T6C and PDB link 1T6D . References reflist 1 cite journal author Hara A, Sy J date 1983 title Guanosine 5 triphosphate, 3 diphosphate 5 phosphohydrolase Purification and substrate specificity journal J. Biol. Chem. volume 258 pages 1678&ndash 83 pmid 6130093 issue 3 hydrolase stub Category EC 3.6.1 Category Enzymes of known structure ... more details
Encyclopedia
top
