radiotherapy, is well recognised. The median survival of patients with metastatic spinalcordcompression ... Systematic review of the diagnosis and management of malignant extradural spinalcordcompression the Cancer ... causes of cordcompression are tumors, but abscess es and granuloma s e.g. in tuberculosis are equally capable of producing the syndrome. Tumors that commonly cause cordcompression are lung cancer non ... Gray in 10 fractions or 8 Gray in 1 fraction is the mainstay of treatment for malignant spinalcordcompression. It is very effective as pain control and local disease control. Some tumours are highly ... mg day may reduce edema around the lesion and protect the cord from injury. It may be given mouth orally or intravenous ly for this indication. Surgery is indicated in localised compression as long ... CNS diseases of the nervous system Category Oncology Category Medical emergencies fr Compression ... more details
Cordcompression may refer to Spinalcordcompression Umbilical cordcompression disambig Short pages monitor This long comment was added to the page to prevent it being listed on Special Shortpages. It and the accompanying monitoring template were generated via Template Longcomment. Please do not remove the monitor template without removing the comment as well. ... more details
style float right clear right Image Spinalcord direv.svg thumb 200px The spinalcord nested in the spine ... thumb 200px right A closer look at the spinalcord div div style float right clear right Image Medulla spinalis Section English.svg thumb 200px right Cross section through cervical spinalcord div div ... s rexed lamina div div style float right clear right Image alarplate.svg thumb 200px right Spinalcord development of the alar and basal plates div div style float right clear right Image Spinalcord tracts English.svg thumb 300px right Spinalcord tracts div Vertebral column The spinalcord is a long ... oblongata specifically . The brain and spinalcord together make up the central nervous system . The spinalcord begins at the Occipital bone and extends down to the space between the first and second ... shorter spinalcord. The spinalcord functions primarily in the transmission of neural ... control numerous reflex es and central pattern generator s. The spinalcord has three major functions A. Serve as a conduit for motor information, which travels down the spinalcord. B. Serve as a conduit for sensory information, which travels up the spinalcord. C. Serve as a center for coordinating ..., USA pages 132 144 url doi id isbn 0 13 981176 1 ref Structure The spinalcord is the main pathway for information connecting the brain and peripheral nervous system. The length of the spinalcord is much shorter than the length of the bony spinal column. The human spinalcord extends from the medulla ... sensory input and motor output coming from and going to the legs. The spinalcord is protected by three ... and it is tightly associated with the surface of the spinalcord. The cord is stabilized within the dura ..., and the anterior median fissure is the groove in the ventral side. Spinalcord segments The human spinalcord is divided into 31 different segments. At every segment, right and left pairs of spinal ... , one on each side of the spinalcord. Spinal nerves, with the exception of C1 and C2, form inside intervertebral ... more details
Orphan date February 2009 Spinalcord untethering is the process in which a tethered spinalcord is relieved. External links http www.sbaa.org site PageServer?pagename ASB tethering Spina Bifida Association on untethering. surgery stub Category Spinalcord Category Neurosurgery ... more details
refimprove date March 2010 Infobox Disease Name Tethered spinalcord syndrome DiseasesDB 34471 ICD10 ... spinalcord syndrome or occult spinal dysraphism sequence refers to a group of Neurology neurological disorder s related to malformations of the spinalcord. ref name columbia http www.columbianeurosurgery.org conditions tethered spinalcord Tethered SpinalCord , Columbia University Dept of Neurosurgery ... the pulling of the spinalcord at the base of the spinal canal, literally a tethered cord . ref name columbia The spinalcord normally hangs loose in the canal, free to move up and down with growth ... cause the spinalcord to stretch as they grow, in adults the spinalcord will stretch in the course of normal activity, usually leading to progressive spinalcord damage if left untreated. ref name ... back pain scoliosis and Urinary incontinence incontinence . Tethered spinalcord syndrome may go undiagnosed .... This delayed presentation of symptoms is related to the degree of strain placed on the spinalcord over time. Tethered spinalcord syndrome appears to be the result of improper growth of the neural ... after spinalcord injury and scar tissue can block the flow of fluids around the spinalcord. Fluid pressure may cause cysts to form in the spinalcord, a condition called syringomyelia . This can lead ... tethered spinalcord syndrome in adults journal Neurosurgical Focus volume 10 issue 1 pages ... is recommended ref cite web title Tethered spinalcord syndrome url http www.ninds.nih.gov disorders .... In adults, surgery to free detether the spinalcord can reduce the size and further development .... Spinalcompression and the resulting relief is a known issue with this disorder. Like with the early ... with tethered spinalcord syndrome have a normal life expectancy. However, most neurological and motor ... cord syndrome url http www.answers.com topic tethered spinalcord syndrome?cat health MEDRS date ... cord to the backbone thickens or hardens and causes downward pressure on the spinalcord. This can ... more details
Infobox Disease Name Spinalcord injuries Image Spinewithcord.jpg Caption View of the vertebral column and spinalcord Width 250 DiseasesDB 12327 DiseasesDB mult DiseasesDB2 29466 ICD10 ICD10 G 95 9 g ... A Spinalcord injury SCI refers to any injury to the spinalcord that is caused by trauma medicine ... 1559 0 oclc doi accessdate ref Depending on where the spinalcord and nerve roots are damaged, the symptoms can vary widely, from pain to paralysis to incontinence. ref SpinalCord Medicine Principles ... ref ref SpinalCord Medicine 2001 Kirshblum S, Campagnolo D, Delisa J. Lippincott Williams & Wilkins ref Spinalcord injuries are described at various levels of incomplete which can vary from having .... In many cases, spinalcord injuries require substantial physical therapy and rehabilitation, especially if the patient s injury interferes with activities of daily life. Spinalcord injuries have ... whiplash . Research into treatments for spinalcord injuries includes controlled hypothermia and stem ... spinal nerve 6 C6 , elbow extension cervical spinal nerve 7 C7 . Traumatic spinalcord injury is classified ... Cord Injury Classification System A indicates a complete spinalcord injury where no motor or sensory function is preserved in the sacral segments S4 S5. B indicates an incomplete spinalcord injury .... C indicates an incomplete spinalcord injury where motor function is preserved below the neurological ... spinalcord injury where motor function is preserved below the neurological level and at least ... normal where motor and sensory scores are normal. Note that it is possible to have spinalcord injury ... Dimitrijevic Dimitrijevic MR. 1988 . Residual motor functions in spinalcord injury. Advances in Neurology ... of subclinical brain influence in clinically complete spinalcord injury discomplete SCI. Journal ... and function in these parts of the body indicates that the spinalcord is only partially damaged. A complete ... 2011 The relative incidence of incomplete injuries compared to complete spinalcord injury has improved ... more details
Infobox Brain Name Anterolateral sulcus of spinalcord Latin sulcus anterolateralis medullae spinalis GraySubject 187 GrayPage 768 Image Spinalcord trirev rexedlamina.svg Caption Spinalcord Ventrolateral sulcus is s5 Image2 Caption2 IsPartOf Components Artery Vein BrainInfoType BrainInfoNumber MeshName MeshNumber The Anterolateral sulcus of spinalcord is a landmark on the anterior side of the spinalcord . It denotes the location at which the ventral fibers leave the spinalcord. The anteriolateral sulcus is less visible than the posterolateral sulcus. ref name LinCardenas2003 cite book author1 Vernon W. Lin author2 Diana D. Cardenas title Spinalcord medicine principles and practice url http books.google.com books?id 3anl3G4No oC&pg PA17 accessdate 19 June 2010 year 2003 publisher Demos Medical Publishing isbn 9781888799613 pages 17 ref See also Anterolateral sulcus of medulla References reflist Gray s Spinalcord Category Spinalcord neuroscience stub ... more details
Unreferenced stub auto yes date December 2009 Orphan date November 2006 Three spinalcord horns are visible in cross sectional views of the spinalcord dorsal horn , ventral horn , and the lateral horn or intermediolateral horn . Each is composed of grey matter gray matter , meaning that the horns comprise mostly neuron al and glia l cell bodies but also have axon s and dendrite s . The dorsal horn is generally associated with sensory neuron s, while the neurons of the ventral horn are mostly motor neuron s. The lateral horn is only present in certain segments of the spinalcord cervical and superior lumbar segments , where it contains neurons innervating limb muscles, preganglionic fiber preganglionic cell bodies of the autonomic nervous system , and sensory relay neuron s. DEFAULTSORT SpinalCord Horn Category Spinalcord Neuroscience stub Ascending nerve tracts control sensory functions, while descending control motor. ... more details
Unreferenced stub auto yes date December 2009 Infobox Anatomy Name Posterior horn of spinalcord Latin cornu posterius medullae spinalis GraySubject 185 GrayPage 753 Image Medulla spinalis Section English.svg Caption Cross section of the spinalcord. The posterior horn is the upper protrusion of grey matter, labeled with 2 Image2 Caption2 Width 350 System Precursor MeshName MeshNumber DorlandsPre c 55 DorlandsSuf 12259855 The posterior horn posterior cornu , dorsal horn , spinal dorsal horn of the spinalcord is the dorsal more towards the back grey matter of the spinalcord. It receives several types of sensory information from the body, including light touch , proprioception , and oscillation vibration . This information is sent from receptors of the skin, bones, and joints through sensory neurons whose cell body cell bodies lie in the dorsal root ganglion . Anatomy The posterior grey horn is subdivided into these laminae. Below are several named examples of each Rexed laminae lamina . Marginal lamina Lamina I Substantia gelatinosa Lamina II Nucleus proprius Laminae III,IV The other laminae are located in other regions of grey matter in the spinalcord. Additional images gallery Image Gray687.png Section of the medulla oblongata through the lower part of the decussation of the pyramids gallery See also Posterior column medial lemniscus pathway Posterior horn of lateral ventricles Anterior horn spinalcord Anterior horn Spinalcord DEFAULTSORT Posterior Horn Of SpinalCord Category Spinalcord Category Neuroanatomy Neuroanatomy stub ... more details
Infobox Anatomy Name PAGENAME Latin sulcus posterolateralis medullae spinalis GraySubject 185 GrayPage 752 Image Spinalcord trirev rexedlamina.svg Caption Spinal cord Dorsolateral sulcus is s3 Image2 Caption2 Precursor System Artery Vein Nerve Lymph MeshName MeshNumber On either side of the posterior median sulcus, and at a short distance from it, the posterior nerve roots are attached along a vertical furrow named the posterolateral sulcus . The portion of the medulla spinalis which lies between this and the posterior median sulcus is named the posterior funiculus . External links UMichAtlas n3a2p3 gray s anatomy stub Spinal cord Category Spinal cord ... more details
Unreferenced stub auto yes date December 2009 Infobox Brain Name Posteromarginal nucleus Latin nucleus marginalis medullae spinalis lamina spinalis I GraySubject GrayPage Image Medulla spinalis Substantia grisea English.svg Caption Medulla spinalis Rexed lamina I labeled at upper left. Image2 Caption2 IsPartOf Components Artery Vein BrainInfoType ancil BrainInfoNumber 984 MeshName MeshNumber DorlandsPre DorlandsSuf The marginal nucleus of spinal cord , or posteromarginal nucleus , or Substantia Marginalis, Rexed lamina I, is located at the most dorsal aspect of the dorsal horn of the spinal cord . The neuron s located here receive input primarily from Lissauer s tract and relay information related to pain and temperature sensation. Pain sensation relayed here cannot be modulated, e.g. pain from burning the skin. Spinal cord DEFAULTSORT Marginal Nucleus Of Spinal Cord Category Back anatomy Category Neurology Neuroscience stub ... more details
Unreferenced date May 2007 Infobox Anatomy Name Anterior horn spinalcord Latin cornu anterius medullae spinalis GraySubject 185 GrayPage 753 Image Medulla spinalis Section English.svg Caption Image2 Caption2 Width 400 System Precursor MeshName MeshNumber DorlandsPre c 55 DorlandsSuf 12259735 The anterior horn of the spinalcord also called the anterior cornu , anterior column or ventral horn is the anatomical terms of location ventral front grey matter section of the spinalcord . The anterior horn contains motor neuron s that affect the axial muscle s while the posterior horn receives information regarding touch and sensation. The anterior horn is where the cell biology cell soma biology bodies of alpha motor neurons are located. Pathology It is these cells that are affected in the so called anterior horn diseases , namely amyotrophic lateral sclerosis , spinal muscular atrophy , Charcot Marie Tooth disease , poliomyelitis , West Nile virus , and progressive muscular atrophy . These motorneurons are also affected in Spinal and Bulbar Muscular Atrophy Kennedy disease . Anatomical details The anterior column anterior cornu, anterior horn , directed forward, is broad and of a rounded or quadrangular shape. Its posterior part is termed the base, and its anterior part the head, but these are not differentiated from each other by any well defined constriction. It is separated from the surface of the medulla spinalis by a layer of white substance which is traversed by the bundles of the anterior nerve roots. In the thoracic region, the postero lateral part of the anterior column projects laterally as a triangular field, which is named the lateral column columna lateralis lateral cornu . See also Alpha motor neuron Gamma motor neuron Beta motor neuron Additional images gallery Image Gray687.png Section of the medulla oblongata through the lower part of the decussation of the pyramids gallery Gray s Spinalcord Category Spinalcord neuroanatomy stub fr Corne ant rieure ja ... more details
Infobox Anatomy Name PAGENAME Latin canalis centralis medullae spinalis GraySubject 185 GrayPage 753 Image Medulla spinalis Section English.svg Caption Cross section through cervical spinal cord. Image2 Medulla spinalis Substantia grisea English.svg Caption2 System MeshName MeshNumber DorlandsPre c 04 DorlandsSuf 12208559 For the engineering project, see Indiana Central Canal . The central canal is the cerebrospinal fluid filled space that runs longitudinally through the length of the entire spinal cord . The central canal is contiguous with the ventricular system of the brain . The central canal represents the adult remainder of the neural tube . It generally occludes, closes off, as we age. ref cite journal author Yasui K, Hashizume Y, Yoshida M, Kameyama T, Sobue G title Age related morphologic changes of the central canal of the human spinal cord journal Acta Neuropathol. volume 97 issue 3 pages 253 9 year 1999 pmid 10090672 doi 10.1007 s004010050982 ref The obex connects the central canal to the fourth ventricle . Syringomyelia is a disease caused by the occlusion of the central canal. Occlusions of the central canal typically occur at the lower cervical and upper thoracic levels. This typically damages white matter fibers that cross in anterior white commissure , leading to the loss of temperature, pain, and coarse touch sensation at the affected levels on contralateral sides. References references External links RocheLexicon 13048.000 3 Category Spinal cord neuroanatomy stub Spinal cord nl Centrale kanaal ja fi Selk ydinkanava ... more details
Infobox Anatomy Name PAGENAME Latin nucleus proprius medullae spinalis laminae spinales III et IV GraySubject GrayPage Image Medulla spinalis Substantia grisea English.svg Caption Medulla spinalis Substantia grisea Image2 Caption2 Precursor System Artery Vein Nerve Lymph MeshName MeshNumber The Nucleus proprius is a layer of the spinal cord adjacent to the substantia gelatinosa . Nucleus proprius constitutes the bulk of the dorsal horn and receives inputs from the dorsal root ganglions that carry sensory information, such as light touch, as well as pain and temperature information. Cells in this nucleus project to deeper lamina of the vertebral arch laminae of the spinal cord , to the posterior column nuclei, and to other supraspinal relay centers including the midbrain , thalamus , and hypothalamus . Rexed laminae III, IV, and V make up the nucleus proprius. ref http cancerweb.ncl.ac.uk cgi bin omd?lamina of Rexed cancerweb.ncl.ac.uk ref Nucleus proprius NP , along with nucleus dorsalis ND are involved in sensing fine touch and proprioception. See also Rexed laminae References references External links DorlandsDict six 000073699 Nucleus proprius http www.pixelatedbrain.com pixbr2005 demo images sld spi cord L2 crdl2 02a.html Diagram at pixelatedbrain.com cite journal author S awomirski J, G uszak J title Structure and topography of the nucleus proprius cornus dorsalis of the spinal cord of horses journal Pol Arch Weter volume 25 issue 4 pages 131 6 year 1986 pmid 3620378 Spinal cord Category Spinal cord neuroscience stub ... more details
A spinalcord stimulator is a device used to exert pulsed electrical signals to the spinalcord to control chronic pain . Spinalcord stimulation SCS , in the simplest form, consists of stimulating electrodes ... both terminate in the dorsal horn the gate of spinalcord. It was hypothesized that input to the latter ..., Shealy et al. implanted the first spinalcord stimulator device directly on the dorsal column ... spinalcord stimulation ref Shimoji K, Higashi H, Kano T, Asai S, Morioka T. Electrical management ... stimulation, spinalcord stimulation, deep brain stimulation , and motor cortex stimulation. Mechanism of action The neurophysiologic mechanisms of action of spinalcord stimulation are not completely understood yet. Linderoth and others ref Linderoth, B. and Foreman, R. 1999 Physiology of spinalcord ... . Spinalcord stimulation mechanism of action . Spine, 27, 2574 2583. ref have noted that the mechanism ... . Spinalcord stimulation Principles of past, present and future practice A review. Journal of Clinical ... type, which are inserted via incision over spinalcord and laminectomy . ref name Dilorenzo ... in the dorsal columns of the spinalcord is much higher than the corresponding vertebral level. For instance ... 10 T10 nerve . ref name Kunnumourath See dermatome anatomy dermatome and SpinalcordSpinalcord segments Spinalcord segments . Electrodes selection For the SCS to be effective, the area of paresthesia .... 2008 . The effects of spinalcord stimulation in neuropathic pain are sustained a 24 month follow up of the prospective randomized controlled multicenter trial of the effectiveness of spinalcord stimulation ... . Spinalcord stimulation versus reoperation for failed back surgery syndrome a prospective, randomized ... al. 2001 . Epidural spinalcord stimulation with a multiple electrode paddle lead is effective in treating ... 1995 . Spinalcord stimulation for chronic low back pain a systematic literature synthesis . Neurosurgery, 37 6 , 1088 1095. ref ref North, R. and Wetzel, T. 2002 . Spinalcord stimulation for chronic ... more details
Orphan date February 2009 SpinalCord Injuries Australia SCIA is a non government organisation which provides advocacy and services to people with spinalcord injury paraplegia , quadriplegia and similar conditions. The organisation recently celebrated its fortieth anniversary as a disability service provider. History SCIA was established in 1967 as the Australian Quadriplegic Association AQA by a group of patients in Prince Henry Hospital in Sydney , Australia . They were unable to leave hospital because there was no accommodation or services to support them in the community. AQA was renamed in 2003. Under SCIA s constitution at least 50 of its board of directors must have a spinalcord injury or similar condition. The founding members were Trevor Annetts, Tom Clarke, Graeme Dunne, David Fox, Peter Harris, George Mamo, Jim McGrath, Robert McKenzie, Alan Moore, John Munday, Cecil Murr, Brian Shirt, Paul Sorgo, Stan Wanless, and Warren Mowbray. David Fox was the first president. They were encouraged to set up an organisation by social worker Gary Garrison, supported by Dr George Burniston. As at August 2008 there are only two surviving founding members of AQA, they being Robert McKenzie and Trevor Annetts, with Annetts currently working at SCIA s Alexandria office and McKenzie retired in Coffs Harbour . They were successful in securing accommodation at Bon Accord Nursing Home in Coogee and later established Ashton House in Maroubra . AQA developed a number of other supported group accommodation residences and transitional accommodation services. Services Services provided by SCIA ... the Community Survival Kit , a list of resources for people with spinalcord injuries and their families ... team also provides individual support and advice for people with spinalcord injury in coastal and inland ... transport in Sydney . ref cite web title SpinalCord Injuries Australia publisher Accessibility Online Pty Ltd month year 2008 url http www.accessibility.com.au directory spinalcord injuries australia ... more details
refimprove date January 2011 original research date January 2011 The SpinalCord Perception is the first novel from Josh Dies Josh Porter who is known mostly for his role as Josh Dies , the singer songwriter for the band Showbread band Showbread . In late 2006, Porter announced that he had written the novel and would be releasing it independently to be sold via his website before it received mainstream publication. An active internet following gathered, consisting largely of Showbread fans who participated in message boards and an ever expanding myspace account in support of the book. Pre order for the novel was accepted for two days in early December in which the entire first printing of the book sold out quickly. The book was reprinted in 2009 and sold via Porter s website. A Book reading tour followed. The book currently fluctuates in availability and is sold only through Porter s Myspace page and at Showbread concerts. The story chronicles the bi polar rants of David Rivers, a mentally unstable substitute teacher. Rivers is most likely an unreliable narrator in most instances and is thought to be a cipher of various hypocrisies in human nature. He ruthlessly condemns other characters for personality traits he claims to find unbearable and usually exemplifies the same traits moments later. The way in which Rivers sees the world is most likely a metaphor for the way the world actually is. For instance, Rivers witnesses Charles, one of Rivers co workers who lives a loose, decadent life style, transforms slowly into a gigantic gila monster and then bites himself with deadly ... readers that The SpinalCord Perception contained some graphic content that may upset certain ... asked if he d read a book called The SpinalCord Percetion saying I have read it. Very underwhelming ... Joshua S. Porter Myspace page http www.freepowerboards.com joshuaporter SpinalCord Perception Forum ... SpinalCord Perception, The Category 2006 novels Category Debut novels Category Postmodernism ... more details
Infobox Anatomy Name Anterior median fissure of spinalcord Latin fissura mediana anterior medullae spinalis GraySubject 185 GrayPage 752 Image Gray675.png Caption A spinal nerve with its anterior and posterior roots. Image2 Gray664.png Caption2 Transverse section of the medulla spinalis in the mid thoracic region. System Precursor MeshName MeshNumber DorlandsPre f 08 DorlandsSuf 12365575 The anterior median fissure of the spinalcord has an average depth of about 3 mm, but this is increased in the lower part of the medulla spinalis . It contains a double fold of pia mater , and its floor is formed by a transverse band of white substance, the anterior white commissure , which is perforated by blood vessels on their way to or from the central part of the medulla spinalis. Additional images gallery Image Gray663.png Diagrams of the medulla spinalis. gallery External links UMichAtlas n2a5p1 Medulla Oblongata, Anterior View eMedicineDictionary anterior median fissure of spinalcord Gray s Spinalcord Category Spinalcord neuroanatomy stub ... more details
Notability date August 2009 The SpinalCord and Brain Injury Research Center at the University of Kentucky College of Medicine is a multidisciplinary center consisting of faculty from multiple departments that focus on neurological Physical trauma trauma research. University of Kentucky Kentucky university stub DEFAULTSORT SpinalCord And Brain Injury Research Center Category University of Kentucky ... more details
Infobox Anatomy Name Central gelatinous substance of spinalcord Latin substantia gelatinosa centralis medullae spinalis GraySubject 185 GrayPage 753 Image Medulla spinalis Substantia grisea English.svg Caption Substantia gelatinosa centralis is Rexed lamina X, labeled at center. Image2 Caption2 System Precursor MeshName Substantia Gelatinosa MeshNumber A08.186.854.610.800 DorlandsPre s 27 DorlandsSuf 12766744 Throughout the cervical and thoracic regions the central canal is situated in the anterior third of the medulla spinalis in the lumbar enlargement it is near the middle, and in the conus medullaris it approaches the posterior surface. It is filled with cerebrospinal fluid , and lined by ciliated, columnar epithelium , outside of which is an encircling band of gelatinous substance, the substantia gelatinosa centralis or central gelatinous substance of spinalcord . This gelatinous substance consists mainly of neuroglia , but contains a few nerve cells and fibers it is traversed by processes from the deep ends of the columnar ciliated cells which line the central canal . It should not be confused with the Substantia gelatinosa of Rolando , which is located more dorsally. External links BrainInfo ancil 993 Gray s Spinalcord Category Spinalcord neuroscience stub ... more details
Infobox Anatomy Name PAGENAME Latin sulcus medianus posterior medullae spinalis GraySubject 185 GrayPage 752 Image Gray664.png Caption Transverse section of the medulla spinalis in the mid thoracic region. Image2 Medulla spinalis Section English.svg Caption2 System Precursor MeshName MeshNumber DorlandsPre s 28 DorlandsSuf 12769176 The posterior median sulcus is very shallow from it a septum of neuroglia reaches rather more than half way into the substance of the medulla spinalis this septum varies in depth from 4 to 6 mm., but diminishes considerably in the lower part of the medulla spinalis. External links UMichAtlas n3a2p3 neuroscience stub Gray s Spinal cord Category Spinal cord ... more details
pathology CNS diseases of the nervous system Lesions of spinalcord and brain Category Histopathology ...Infobox Disease Name PAGENAME Image Gray672.png Caption Diagram of the principal fasciculi of the spinalcord. In subacute combined degeneration of spinalcord, the combined refers to the fact that the dorsal column s and lateral corticospinal tract s are both affected, in contrast to tabes dorsalis which is selective for the dorsal columns. DiseasesDB 12591 ICD10 ICD10 G 32 0 g 30 , ICD10 E 53 8 e 50 ICD9 ICD9 336.2 , ICD9 266.2 ICDO OMIM MedlinePlus 000723 eMedicineSubj eMedicineTopic MeshID D052879 Subacute combined degeneration of spinalcord , also known as Ludwig Lichtheim Lichtheim s disease, ref WhoNamedIt synd 492 ref ref L. Lichtheim. Zur Kenntnis der pernici sen An mie. Verhandlungen des Deutschen Kongress f r innere Medizin, 1889, 6 84 96. 42 1887. ref refers to degeneration of the posterior and lateral columns of the spinalcord as a result of vitamin B12 deficiency vitamin B sub 12 sub deficiency most common , vitamin E deficiency or Friedrich s ataxia . It is usually associated with pernicious anemia . Presentation The pathological findings of subacute combined degeneration consist of patchy losses of myelin in the dorsal and lateral columns. Patients present with weakness of legs, arms, trunk, tingling and numbness that progressively worsens. Vision changes and change of mental state may also be present. Bilateral spastic paresis may develop and pressure, vibration and touch sense are diminished. A positive Babinski sign may be seen. Prolonged deficiency of vitamin B12 vitamin B sub 12 sub leads to irreversible nervous system damage. If someone is deficient in vitamin B sub 12 sub and folic acid, the vitamin B sub 12 sub deficiency must be treated first to avoid precipitating subacute combined degeneration of the cord. Treatment Therapy with vitamin B sub 12 sub results in partial to full recovery, depending on the duration and extent of neurodegeneration ... more details
wiktionary cordCord may refer to String or rope Cord sewing , a trimming made of multiple strands of yarn twisted together The spinalcordCord Automobile , a former American car marque founded by Errett Lobban Cord The cord volume , used to measure firewood In electronics, a cable Vibrating string A power cord or extension cord Mycelial cord , a structure, used by fungi to transfer nutrients over larger distances. Umbilical cord , a tube that connects a developing embryo or fetus to its placenta Cord band , a British rock group Cord film Cord film , a 2000 film starring Daryl Hannah and Jennifer Tilly Cord unit , a unit of measurement for wood used in North America Alex Cord , an actor and writer Canadian Organization for Rare Disorders , a non profit health organization Chronic obstructive respiratory disease , an alternate name for chronic obstructive pulmonary disease See also lookfrom cord intitle cord Chord disambiguation String disambiguation disambig de Cord hi io Kordono ro Cord dezambiguizare simple Cord ... more details
CORD may refer to Chronic obstructive pulmonary disease COPD , Chronic Obstructive Pulmonary Disease Congress on Research in Dance , a professional society for dance research Christian Outreach for Relief & Development , humanitarian organization, based in UK Council of Emergency Medicine Residency Directors , a scientific organization disambig ... more details
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