Multiple issues orphan November 2006 context October 2009 Small T intron exist in some plasmid vector s used for protein expression . The function of this intron in the vectors is unknown, but it is theorized that it might be involved in splicing or translation efficiency. ref name pmid1690852 cite journal author Huang MT, Gorman CM title The simian virus 40 small t intron, present in many common expression vectors, leads to aberrant splicing. journal Mol Cell Biol volume 10 issue 4 pages 1805 10 year 1990 pmid 1690852 ref ref name pmid1654158 cite journal author Hunt AG, Mogen BD, Chu NM, Chua NH title The SV40 small t intron is accurately and efficiently spliced in tobacco cells. journal Plant Mol Biol volume 16 issue 3 pages 375 9 year 1991 pmid 1654158 ref Vectors contain such as pME18s contain it. References reflist DEFAULTSORT Small T Intron Category Gene expression Cell biology stub ... more details
For the interferon based drug used in viral and cancer treatments Intron A Image Gene.png right thumbnail 270px Diagram of the location of introns and exons within a gene. An intron is any nucleotide sequence ... The term intron refers to both the DNA sequence within a gene, and the corresponding sequence in RNA ... RNA tRNA . When proteins are generated from intron containing genes, RNA splicing takes place as part ... biology translation . The word intron is derived from the term intragenic region , i.e. a region ... editing , in addition to introns. Simple illustration of an intron and RNA splicing Introns and the process ... If there were a single intron within this sequence, it would look something ... exon and intron sequences To remove the intron, the sequences corresponding to the intron and exons ... the boundaries between the exons and intron by even a single letter will result in a nonsensical ... 2. Cleavage at intron exon junctions Next, the sequence must be cut precisely at the boundaries between the exons and the intron OUTSIDEOFADOGABOOKISMANSBE GUITUITGLSAJSAKHDLAYSIOEYASHDKLSALKDNKLASNDKLASKGDASJKBDNKNSKD ... together to generate the final message. The excised intron is usually broken down to its component ... or Medicine in 1993 for Phillip Allen Sharp and Richard J. Roberts . The term intron was introduced ... genomic analysis of fungal genomes reveals intron rich ancestors journal Genome Biol. volume 8 issue ... intron containing RNA molecules is superficially similar, as described above. However, different types of introns were identified through the examination of intron structure by DNA sequence analysis ... intron group I introns that are removed by Ribozyme RNA catalysis . Self splicing group II intron s that are removed by Ribozyme RNA catalysis Group III intron s are proposed to be a fifth family, but little ... intron sequences located at the boundaries between introns and exons. ref cite journal author Padgett ... near the 3 end of the intron that becomes covalently linked to the 5 end of the intron during ... more details
Infobox animanga Header name Intron Depot 1 image caption ja kanji ja romaji genre Fantasy , Cyberpunk , Infobox animanga Print type manga author Masamune Shirow publisher Seishinsha demographic magazine first July 17, 1992 last volumes volume list Infobox animanga Footer Intron Depot 1 is a collection of Masamune Shirow s full color works. The volume itself is 148 210 mm x 285 mm pages. It encompasses 226 illustrations from 1981 to 1991, 193 of which are in full color. It is a wide ranging collection, as one might expect from a work surveying 10 years of a professional artist s life. The foreword written by Masamune Shirow indicates that only a small sample of works is not represented, some works done for fanzines, or sent off to other individuals, and 34 color pages were left out from Ghost in the Shell because he felt that might devalue that work. Everything from Appleseed manga Appleseed to Orion manga Orion are well represented in Intron Depot 1, some pictures are reproductions of paintings, others book covers, manga pages, or drafts. One feature of Intron Depot 1 is that all of the works are presented with a small aside from Shirow as to his thoughts on them. Another is that he includes a number of what he considers to be his mistakes, and is generally very critical of his work over all. The commentary itself is somewhat whimsical in tone. It might present some seed of inspiration for an image, critique, or ponder the functionality of a pictured object, or provide some perspective on technique, story, or history associated with the work. Intron Depot 1 in two spots in particular is quite graphic. One panel involves a graphic drawing of a lesbian m nage trois, and another significant gore. On balance it is a collection of guns, swords, girls, gadgets, cyborgs and mecha . Chapter pieces Poster 3 Contents 2 Appleseed manga Appleseed 43 Black Magic manga Black Magic 10 Black Magic M 66 10 Game & Etc. 15 Ghost In The Shell The Ghost In The Shell 39 Dominion ... more details
Rfam box acc RF00028 description Group I catalytic intron abbreviation Intron gpI avg length 349.90 avg identity 59.00 type Intron se Eddy SR ss Published PMID 2197983 release 10.0 Group I introns are large ... in a free 3 OH group at the upstream exon and the exoG being attached to the 5 end of the intron. Then the terminal G omega G of the intron swaps the exoG and occupies the G binding site to organize the second ... of the catalytic intron. Image GI catalysis.jpg center Two metal ion mechanism seen in protein polymerases and phosphatases was proposed to be used by group I and group II intron s to process the phosphoryl ... proven by a recently resolved high resolution structure of the Azoarcus group I intron. ref cite journal last Stahley first MR coauthors Strobel SA year 2006 title RNA splicing group I intron ... Image PDB 1grz EBI.png thumb 200px left A 3D representation of the Group I catalytic intron. This view ... A 3D representation of the Group I catalytic intron. This is the crystal structure of a phage Twort ... thumb 200px right A 3D representation of the Group I catalytic intron. This is the structure of the Tetrahymena ... 62 year 2004 pmid 15525509 doi 10.1016 j.molcel.2004.10.003 ref Intron folding Since early 1990s, scientists started to study how the group I intron achieves its native structure in vitro , and some ... to be restricted to a few tRNA and mRNA genes of the chloroplasts and mitochondria. Both intron early and intron late theories have found evidences in explaining the origin of group I introns. Some group I introns encode homing endonuclease HEG , which catalyzes intron mobility. It is proposed that HEGs move the intron from one location to another, from one organism to another and thus account for the wide ... that they live by. A small number of group I introns are also found to encode a class of proteins called maturases that facilitate the intron splicing. See also GISSD Group I Intron Sequence and Structure ... together with a group I intron to regulate the expression of a gene References reflist 1 Further reading ... more details
Group III intron is a class of intron s found in mRNA genes of chloroplasts in euglenoid protist s. They have a conventional Group II intron group II type dVI with a bulged adenosine, a streamlined dI, no dII dV, and a relaxed splice site consensus. Splicing is by two transesterification reactions with a dVI bulged adenosine as initiating nucleophile the intron is excised as a lariat. Clarify date August 2009 Citation needed date August 2009 Discovery and identification Montandon,P. and Stutz,E. 1984 ref cite journal author Montandon PE, Stutz E title Nucleotide sequence of a Euglena gracilis chloroplast genome region coding for the elongation factor Tu evidence for a spliced mRNA journal Nucleic Acids Res. volume 11 issue 17 pages 5877 92 year 1983 month September pmid 6310519 pmc 326324 doi 10.1093 nar 11.17.5877 url http nar.oxfordjournals.org cgi pmidlookup?view long&pmid 6310519 ref and Hallick,R.B. et al. 1988 and 1989 reported examples of a novel type of introns in Euglena chloroplast . In 1989, David A.Christopher and Richard B.Hallick proposed the title, Group III introns to identify this new class with the following characteristics ref cite journal author Christopher DA, Hallick RB title Euglena gracilis chloroplast ribosomal protein operon a new chloroplast gene for ribosomal protein L5 and description of a novel organelle intron category designated group III journal Nucleic Acids Res. volume 17 issue 19 pages 7591 608 year 1989 month October pmid 2477800 pmc 334869 doi 10.1093 nar 17.19.7591 url http nar.oxfordjournals.org cgi pmidlookup?view long&pmid 2477800 ref Group III introns are much shorter than other self splicing intron classes, ranging from 95 to 110 ... hand, Christopher and Hallick stated By contrast, the smallest Euglena chloroplast group II intron .... In 1994, discovery of a group III intron with a length of one order of magnitude longer indicated ... Intron Category RNA Category Ribozymes Category RNA splicing ... more details
Orphan date February 2011 infobox biodatabase title EID logo File Database.png description database of protein coding intron containing genes. scope organism center laboratory Department of Molecular Biology, Harvard University, Cambridge, MA 02138, USA. author S Saxonov pmid Saxonov & al. 2000 ref name pmid10592221 released standard format url http mcb.harvard.edu gilbert EID download webservice sql sparql webapp standalone license versioning frequency curation bookmark version the Exon Intron Database EID is a database of Alternative splicing spliced mRNA sequences ref name pmid10592221 cite journal quotes yes last Saxonov first S authorlink coauthors Daizadeh I, Fedorov A, Gilbert W year 2000 month Jan title EID the Exon Intron Database an exhaustive database of protein coding intron containing genes journal Nucleic Acids Res. volume 28 issue 1 pages 185 90 publisher location ENGLAND issn 0305 1048 pmid 10592221 bibcode oclc id url pmc 102483 language eng format accessdate laysummary laysource laydate quote ref See also Alternative splicing Exon Intron References references External links http mcb.harvard.edu gilbert EID http www.mco.edu bioinfo eid index.html Category Biological databases Category Gene expression Category Spliceosome Category RNA splicing Biodatabase stub ... more details
Intron mediated enhancement IME is the ability of an intron sequence to enhance the gene expression expression of a gene containing that intron. The term was first defined in a 1990 publication that investigated the enhancing effects of two specific maize introns. ref cite journal last1 Mascarenhas first1 D last2 Mettler first2 IJ last3 Pierce first3 DA last4 Lowe first4 HW year 1990 url http www.springerlink.com content m58671550362166l title Intron mediated enhancement of heterologous gene expression in maize journal Plant Molecular Biology volume 15 issue 6 pages 913 920 quote no doi 10.1007 BF00039430 ref Since then there have been a number of publications that have investigated this phenomenon, though the mechanism s by which IME works are still not completely understood. When testing to see whether any given intron produces an IME effect, it is typical to compare the expression of two DNA construct constructs , one containing the intron and one without it, and to express the difference between the two results as a Multiplication fold increase in enhancement. Not all introns enhance gene expression, but those that do typically enhance expression between 2 and 10 fold relative to an intronless control. ref cite journal doi 10.1017 S1355838202020551 last1 Rose first1 A year 2002 pages 1444 53 pmid 12458797l issue 11 title Requirements for intron mediated enhancement of gene expression in Arabidopsis journal RNA volume 8 format pmc 1370350 dead link date May 2010 ref Introns that enhance expression have been detected in humans, ref cite journal last1 Jonsson first1 JJ last2 Foresman first2 MD last3 Wilson first3 N last4 McIvor first4 RS year 1990 pmid 1620616 title Intron ... Intron journal Plant Physiology volume 123 issue 3 pages 1005 1014 doi 10.1104 pp.123.3.1005 ... Sala first3 F last4 Breviario first4 D year 2002 title A long leader intron of the Ostub16 rice tubulin ... Reflist DEFAULTSORT Intron Mediated Enhancement Category Gene expression ... more details
Image IntronGroupII.jpg thumb 280px right Structure of group II intron Group II introns are a large class of self catalytic ribozymes as well as mobile genetic element found within the genes of all three kingdoms of life. Ribozyme activity e.g., Self RNA splicing splicing can occur under high salt conditions in vitro , however, assistance from proteins is required for in vivo splicing. In contrast to group I introns, intron excision occurs in the absence of Guanosine triphosphate GTP and involves the formation of a lariat, with an A residue branchpoint strongly resembling that found in lariats formed during splicing of nuclear pre mRNA. It is hypothesized that pre mRNA splicing see spliceosome may have evolved from group II introns due to the similar catalytic mechanism as well the structural similarity of the Domain V substructure to the U6 U2 extended snRNA. Finally, their ability to site specifically mobilize to new DNA sites has been exploited as a tool for biotechnology. Structure and catalytic site The secondary structure of group II introns is characterized by six typical stem ... over the complete intron structure. The few strictly conserved primary sequences are the consensus ... site. Group II catalytic intron Group II catalytic introns are found in rRNA , tRNA and mRNA of organelle ... only domains V and VI. A subset of group II intron s also encode essential splicing proteins ... , and long range intronintron and intron exon interactions are important for splice site positioning ... the lariat from the 3 splice site. See also Intron Splice site Splicing genetics Spliceosomal Nuclear introns Group I catalytic intron Group I intron Group III intron Twintron LtrA References cite ... intron journal Nat. Struct. Mol. Biol. volume 12 issue 7 pages 626 7 year 2005 month July pmid 15980867 ..., Perlman PS, Pyle AM year 2001 title Control of branch site choice by a group II intron journal EMBO ... RF00029 name Group II catalytic intron Category RNA Category Ribozymes Category RNA splicing ... more details
Orphan date March 2011 infobox biodatabase title U12DB logo File Database.png description orthologous U12 type spliceosomal introns. scope organism center laboratory author Tyler S Alioto pmid Alioto & al. 2007 ref name pmid17082203 released 2006 standard format url http genome.imim.es cgi bin u12db u12db.cgi download webservice sql sparql webapp standalone license versioning frequency curation bookmark version U12 Intron Database U12DB is a database of U12 minor spliceosomal RNA U12 type introns of sequenced eukaryotic genomes. ref name pmid17082203 cite journal quotes yes last Alioto first Tyler S authorlink year 2007 month Jan title U12DB a database of orthologous U12 type spliceosomal introns journal Nucleic Acids Res. volume 35 issue Database issue pages D110 5 publisher location England issn pmid 17082203 doi 10.1093 nar gkl796 bibcode oclc id url pmc 1635337 language eng format accessdate laysummary laysource laydate quote ref References references See also U12 minor spliceosomal RNA External links http genome.imim.es cgi bin u12db u12db.cgi Biodatabase stub Category Biological databases Category Gene expression Category Spliceosome Category RNA splicing ... more details
. wiktionarypar small petite Small may refer to Something of low number Something of low size Lower case is the small form case of a letter SMALL , an ALGOL like programming language Pawn programming language , a C like language formerly known as Small A term to describe smaller aircraft for purposes of air traffic control . Specifically, small refers to a plane having a maximum takeoff weight of less than 41,000 pounds. Small journal Small , a peer reviewed interdisciplinary journal in the field of nanoscience. The Cosmos Rocks SmallSmall , a song from the Queen Paul Rodgers album The Cosmos Rocks . People Albion Woodbury Small 1854 1926 , founded the first Department of Sociology in the United States at the University of Chicago Ambrose Small 1863 vanished 1919 , Canadian theatre magnate Archie Small born 1889 , English footballer with Southampton Bertrice Small born 1937 , U.S.American writer of historical and erotic romance novels Brendon Small born 1975 ,American actor, composer, and musician Bruce Small 1895 1980 , Australian businessman and politician Charles A. Small , Director of The Yale Initiative for the Interdisciplinary Study of Anti Semitism Charlotte Small , M tis wife of David Thompson explorer Chris Small born 1973 , Scottish professional snooker player Edward Small 1891 1977 , film producer Elisha Small died 1842 , American sailor Eric Small , television and film Producer, Writer, Director Frank Small, Jr. 1896 1973 , represented the fifth district of the state of Maryland in the United States House of Representatives Fred Small born 1952 , American singer songwriter Gladstone Small born 1961 , former England cricketer Heather Small born 1965 , British soul singer Henry Small 1881 1946 , English footballer with Southampton and Manchester United Jack Small 1765 1836 , English cricketer Jack Small footballer 1889 1946 , English footballer with Sunderland and Southampton James Edward Small 1798 1869 , lawyer, judge and political figure in Canada ... more details
About the ALGOL like programming language the scripting language formerly named Small Pawn programming language SMALL , Small Machine Algol Like Language, is a computer programming programming programming language language developed by Dr. Nevil Brownlee of Auckland University . History The aim of the language was to enable people to write ALGOL like code that ran on a small machine. It also included the string type for easier text manipulation. SMALL was used extensively from about 1980 to 1985 at Auckland University as a programming teaching aid, and for some internal projects. Originally written to run on a Burroughs Corporation B6700 Main frame in Fortran IV, subsequently rewritten in SMALL and ported to a DEC PDP 10 Architecture on the Operating System TOPS 10 and IBM S360 Architecture on the Operating System VM Conversational Monitor System CMS . About 1985, SMALL was your genital size Object oriented programming object oriented features added to handle structures that were missing from the early language , and to formalise file manipulation operations. See also porn Lua programming language Squirrel programming language References http www.caida.org home seniorstaff nevil.xml Nevil Brownlee Category Algol programming language family Category Systems programming languages Category Procedural programming languages Category Object oriented programming languages ... more details
Notability music See WP NSONG date March 2010 Infobox single Name Small Bones Small Bodies Cover Artist Future of the Left from Album Curses Future of the Left album Curses Released September 10, 2007 Format Vinyl record 7 Recorded Genre Indie rock Label Too Pure Producer Richard Jackson Chart position Last single Adeadenemyalwayssmellsgood br 2007 This single Small Bones Small Bodies br 2007 Next single Manchasm br 2008 Small Bones Small Bodies is the third single by Cardiff band Future of the Left . It was released on September 10th by Too Pure . NOTOC Track listing Small Bones Small Bodies The Big Wide O I Need To Know How To Kill A Cat References references Category 2007 singles Category Future of the Left songs Category Too Pure singles 2000s song stub ... more details
Small Heath can refer to Small Heath, Birmingham , an area of Birmingham, England Birmingham Small Heath UK Parliament constituency Small Heath or Small Heath Alliance , former names of Birmingham City F.C. Small Heath butterfly Coenonympha pamphilus disambig de Small Heath ... more details
Mike Small may refer to Mike Small footballer Mike Small golfer Mike Small author See also Michael Small , American film score composer Michael Small diplomat , Canadian ambassador to Cuba preceding Alexandra Bugailiskis hndis Small, Mike ... more details
Small eared may refer to Small eared Pygmy Rice Rat , rodent species from South America Small eared shrew , group of relatively small shrews with short ears which are usually not visible and short tails Small eared skink , moderately small skink disambig ... more details
Small Wonder may refer to Small Wonder TV series Small Wonder TV series , 1985 1989 Small Wonder Records , a UK record label that released mainly records by punk rock bands disambig fr Small Wonder it Small Wonder ... more details
Small Worlds may refer to Small Worlds presentation , a presentation by Raph Koster about MMORPG conventions Small Worlds Torchwood Small Worlds Torchwood , an episode of Torchwood small worlds , a play by Eva Maler SmallWorlds , a 3D virtual world See also Small world disambiguation disambig ... more details
Small Constitution or Little Constitution , lang pl Ma a Konstytucja can refer to three constitution s of Poland Small Constitution of 1919 Small Constitution of 1947 Small Constitution of 1992 disambig pl Ma a Konstytucja ... more details
Small Steps may refer to Small Steps novel Small Steps novel , a novel by Louis Sachar Small Steps album Small Steps album , an album by Heiruspecs Small Steps The Year I Got Polio , a book by Peg Kehret See also Small Steps, Heavy Hooves , an album by Dear and the Headlights Small step semantics , in computer science disambig ... more details
John Small may refer to In chronological order by year of birth John Small British Army officer 1726 1796 , active in the American Revolutionary War John Small cricketer 1737 1826 , English cricketer Jack Small 1765 1836 , English cricketer John Small politician 1746 1841 , political figure in Upper Canada John Small librarian John Small 1828 1886 , librarian of Edinburgh University John Small Member of Parliament 1831 1909 , member of the Canadian House of Commons John Francis Small , Member of the United Kingdom Parliament for County Wexford UK Parliament constituency County Wexford , 1883 1885 and South Down, 1885 1886 John Humphrey Small 1858 1946 , U.S. Representative from North Carolina John Kunkel Small 1869 1938 , American botanist John Small American football born 1946 , American football player In chronological order by year of birth hndis name Small, John ... more details
James Small may refer to James Small inventor 1730&ndash 1793 James Small rugby player born 1969 James Edward Small 1798&ndash 1869 , early Canadian judge and political figure Jim Small born 1933 , Australian politician Jim Small baseball born 1937 , American baseball player Hndis name Small, James ... more details
Charles Small may refer to Charles A. Small , lecturer at Yale University Charlie Small , MLB player Charlie Small writer , pseudonymous children s author Charlie Smalls , composer and songwriter Charles John Small , former List of Canadian ambassadors to Afghanistan Canadian ambassador to Afghanistan hndis name Small, Charles DEFAULTSORT Small, Charles ... more details
In mathematics , the term small set may refer to Small set category theory Small set combinatorics See also Ideal set theory Natural density Large set Ramsey theory mathdab ... more details
Small world may refer to tocright Novels Small World novel Small World novel , a 1981 horror novel by Tabitha King Small World 2008 novel Small World 2008 novel , a novel by Matt Beaumont Small World An Academic Romance , a 1984 comic novel by David Lodge Music Small World album Small World album , a 1988 album by Huey Lewis and the News Small World , a song from the musical Gypsy A Musical Fable Sciences Small world experiment , a series of social network experiments conducted by Stanley Milgram Small world network , a generalization of the small world phenomenon to non social networks Small world routing , routing methods for small world networks Television Small World , a Cartoon Network United States Cartoon Network program Small World , a television show hosted by Edward R. Murrow Small world TV miniseries Small world TV miniseries , a miniseries based on the David Lodge novel Other uses Small World board game Small World board game , a board game by Days of Wonder Smallworld , a Geographic Information System targeted to utilities from General Electric Smallworld Cable , a Scottish cable television and broadband provider Small World Software , a former internet technology consultancy company, now part of iXL aSmallWorld , an internet network See also Small Worlds disambiguation It s a Small World disambiguation disambig de Small World ... more details
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