Infobox disease Name Sarcoma Image Caption DiseasesDB ICD10 ICD9 ICDO ICDO 8800 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D012509 A sarcoma from the Greek sarx meaning flesh is a cancer that arises ... 000094521 sarcoma . ref clarify date October 2010 It should be contextually clarified explained why ... layer, ref MeshName Sarcoma ref which forms the bone , cartilage , and fat tissues. This is in contrast ... . However, due to an evolving understanding of tissue origin, the term sarcoma is sometimes applied ... H, Kawabata A, Murano A, et al. title Monophasic epithelial synovial sarcoma arising in the temporomandibular ... S0901 5027 07 00105 1 ref The term soft tissue sarcoma is used to describe tumors of soft tissue , ref name urlSoft Tissue Sarcoma Home Page National Cancer Institute cite web url http www.cancer.gov cancertopics types soft tissue sarcoma title Soft Tissue Sarcoma Home Page National Cancer Institute ... thumb Optical Coherence Tomography OCT image of a sarcoma Tissue Sarcomas are given a number of different ... . ref cite journal author Buecker, P title Sarcoma A Diagnosis of Patience journal ESUN volume ... 9130 3 Malignant Schwannoma 9560 3 9561 3 Osteosarcoma 9180 3 9190 3 Soft tissue sarcoma s, including Alveolar soft part sarcoma 9581 3 Angiosarcoma 9120 3 Phyllodes tumor Cystosarcoma Phyllodes ... tumor 8806 3 Epithelioid Sarcoma 8804 3 Extraskeletal chondrosarcoma 9220 3 Extraskeletal osteosarcoma 9180 3 Fibrosarcoma 8810 3 Hemangiopericytoma 9150 Hemangiosarcoma 9120 3 Kaposi s sarcoma 9140 3 Note that Kaposi s sarcoma is not a true sarcoma as it derives from epithelial cells Leiomyosarcoma ... fibrous histiocytoma 8830 3 Neurofibrosarcoma 9540 3 Rhabdomyosarcoma 8900 8920 Synovial sarcoma 9040 ... per year. Gastrointestinal stromal tumor GIST is the most common form of sarcoma, with approximately .... ref cite journal author Darling, J title A Different View of Sarcoma Statistics journal ESUN volume 4 issue 6 year 2007 url http sarcomahelp.org sarcoma statistics.html accessdate 2009 04 15 ref Some ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO ICDO 8804 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Epithelioid sarcoma is a rare mesenchymal soft tissue tumor with an epithelioid pattern. It often occurs in the extremities of young people. BR BR Diagnosis is often delayed because of the unusual nature of the tumor. External links http sarcomahelp.org epithelioid sarcoma.html Epithelioid Sarcoma in the Sarcoma Learning Center http www.ralphmoss.com html epithelioid sarcoma.shtml The Moss Reports, accessed January 3 2008 http www.thedoctorsdoctor.com Diseases epithelioidsarcoma.htm The Doctors Doctor, accessed January 3 2008 cite journal author Kato H, Hatori M, Kokubun S, et al. title CA125 expression in epithelioid sarcoma journal Jpn. J. Clin. Oncol. volume 34 issue 3 pages 149 54 year 2004 month March pmid 15078911 url http jjco.oxfordjournals.org cgi content full 34 3 149 http findarticles.com p articles mi qa3725 is 200309 ai n9288892 Archives of Pathology & Laboratory Medicine, Sep 2003, accessed January 3 2008 http mylefthand themovie.com default.aspx My Left Hand, documentary film about one man s battle with epithelioid sarcoma Category Types of cancer category Dermal and subcutaneous growths ... more details
Infobox disease Name Synovial sarcoma Image Caption DiseasesDB ICD10 ICD9 ICDO ICDO 9040 3 9043 3 OMIM 300813 MedlinePlus eMedicineSubj eMedicineTopic MeshID D013584 A synovial sarcoma is a rare form of cancer which usually occurs near to the joints of the arm or leg. It is one of the soft tissue sarcoma s. Synovial sarcoma was originally coined early in the 20th century as some thought that the microscopic ... and heart. Synovial sarcoma occurs most commonly in the young, representing about 8 of all soft tissue sarcomas ref name ferrari 2006 cite web title Synovial Sarcoma url http sarcomahelp.org learning ... Two cell types can be seen microscopically in synovial sarcoma. One fibrous type, known as a spindle ... in appearance. Classical synovial sarcoma has a biphasic appearance with both types present. Synovial sarcoma can also appear to be poorly differentiated or to be monophasic fibrous, consisting ... soft tissue sarcoma s, there is no universal grading system for reporting histopathology results ... Most, and perhaps all, cases of synovial sarcoma are associated with a reciprocal Chromosomal translocation ... itself is definitional of synovial sarcoma. ref cite journal author Pfeifer JD, Hill DA, O Sullivan ... The diagnosis of synovial sarcoma is typically made based on histology and is confirmed by the presence ... L title Should molecular testing be required for diagnosing synovial sarcoma? A prospective study ... ref This translocation event between the SYT gene on chromosome 18 and one of 3 Synovial sarcoma ... sarcoma pathogenesis through dysregulation of gene expression. ref name atlas 2002 There is some association ... type on the clinical behavior of synovial sarcoma a multi institutional retrospective study of 243 ... Synovial sarcoma usually presents with an otherwise asymptomatic swelling or mass, although general ... sarcoma treatment and is curative in approximately 20 70 of patients,depending on the particular ... al. title Synovial sarcoma a multivariate analysis of prognostic factors in 112 patients with primary ... more details
Infobox disease Name Ewing sarcoma Image Ewing sarcoma tibia child.jpg Caption X Ray of a child with Ewing sarcoma of the tibia DiseasesDB 4604 ICD10 ICD9 ICD9 170.9 ICDO ICDO 9260 3 OMIM 133450 MedlinePlus 001302 eMedicineSubj ped eMedicineTopic 2589 MeshID D012512 Ewing sarcoma is a malignant round ... sarcoma and primitive neuroectodermal tumor s, these are sometimes grouped together in a category ... and treatment of Ewing sarcoma journal Jpn. J. Clin. Oncol. volume 37 issue 2 pages 79 89 year ... commonly related to bone. Ewing sarcoma occurs most frequently in male teenagers , with a male ... Medical tumours of the chest wall. Solitary plasmacytoma and Ewing sarcoma journal J. Thorac. Cardiovasc ..., Ewing sarcoma can have characteristics of both mesoderm al and ectoderm al origin, making it difficult to classify. ref name pmid14600088 cite journal author Longtin R title Ewing sarcoma a miracle drug ... between chromosomes can cause cells to become cancerous. Ewing sarcoma is the result of a translocation ... oncogenic transformation in Ewing sarcoma journal PLoS ONE volume 3 issue 4 pages e1965 year 2008 ... Ewing s sarcoma translocation, t 21 22 , fuses the EWS gene to another ETS family transcription factor ... BS, et al. title A variant Ewing s sarcoma translocation 7 22 fuses the EWS gene to the ETS gene ETV1 ... Clinical findings Ewing sarcoma is more common in males and usually presents in childhood or early adulthood ..., Kovar H, Paulussen M, et al. title Ewing sarcoma family of tumours current management journal Oncologist ... Image Ewing s sarcoma MRI nci vol 1832 300.jpg thumb Magnetic resonance imaging slice showing Ewing s sarcoma of the left hip white area shown right . On conventional radiography radiographs , the most ... of malignant small round cell tumours which include Ewing s sarcoma, bone lymphoma and small ... Sarcoma Imaging ref In the United Kingdom an average of six children per year are diagnosed, mainly ..., Laschinger K title Ewing sarcoma family of tumours an overview from diagnosis to survivorship journal ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO M9755 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D054747 Histiocytic sarcoma is a tumor derived from histiocyte s. ref name pmid18239326 cite journal author Yoshida C, Takeuchi M title Histiocytic sarcoma identification of its histiocytic origin using immunohistochemistry journal Intern. Med. volume 47 issue 3 pages 165 9 year 2008 pmid 18239326 doi 10.2169 internalmedicine.47.0386 url http joi.jlc.jst.go.jp JST.JSTAGE internalmedicine 47.0386?from PubMed format dead link date May 2010 ref The tumor is often positive for CD163 ref name pmid15696128 cite journal author Vos JA, Abbondanzo SL, Barekman CL, Andriko JW, Miettinen M, Aguilera NS title Histiocytic sarcoma a study of five cases including the histiocyte marker CD163 journal Mod. Pathol. volume 18 issue 5 pages 693 704 year 2005 month May pmid 15696128 doi 10.1038 modpathol.3800346 ref and can appear in the thyroid . ref name pmid18386009 cite journal author De Vos FY, Gerding MN, Arends JW, Wegman JJ title Histiocytic sarcoma localised in the thyroid a case report journal Ann. Hematol. volume 87 issue 8 pages 681 2 year 2008 month August pmid 18386009 pmc 2441588 doi 10.1007 s00277 008 0473 0 ref References reflist Category Oncology Category Sarcoma neoplasm stub Histiocytosis Soft tissue tumors and sarcomas ... more details
Infobox disease Name Sarcoma botryoides Image Caption DiseasesDB 1557 ICD10 ICD9 ICDO 8910 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D018233 Sarcoma botryoides or botryoid sarcoma ref DorlandsDict seven 000094526 botryoid sarcoma ref or botryoid rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma , that can be observed in the walls of hollow, mucosa lined structures such as the nasopharynx, common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. The name comes from the gross appearance of grape bunches botryoid in Greek . Histology Under the microscope one can see rhabdomyoblast s that may contain cross striations. Tumor cells are crowded in a distinct layer beneath the vaginal epithelium cambium layer . Clinical characteristics For botryoid rhabdomyosarcoma of the vagina, the most common clinical finding is vaginal bleeding ref Rahaman, J and Cohen, CJ. Gynecologic Sarcomas. in Holland Frei Cancer Medicine 6th Ed. Kufe, DW et al. editors. BC Decker Inc, Hamilton, Ontario, 2003. ref but vaginal bleeding is not specific for sarcoma botryoides other vaginal cancer s are possible. They may appear as a polypoid mass, somewhat yellow in color and are friable thus, they possibly may break off, leading to vaginal bleeding or infections. Epidemiology Sarcoma botryoides normally is found in children under 8 years of age. Onset of symptom s occurs at age 3 years 38.3 months on average. ref cite journal author Hilgers R title Pelvic exenteration for vaginal embryonal rhabdomyosarcoma a review journal Obstet Gynecol volume 45 issue 2 pages 175 80 year 1975 pmid 1090863 ref Cases of older women with this condition have also been reported. ref cite journal author Reynolds E, Logani S, Moller K, Horowitz ... DEFAULTSORT Sarcoma Botryoides Category Gynecological cancer Category Pediatric cancers Category Rare cancers de Sarcoma botryoides ... more details
A uterine sarcoma is a malignant tumor that arises from the smooth muscle or connective tissue of the uterus . Histology Subtypes include leiomyosarcoma s, endometrial stromal sarcoma s and other sarcomas. ref name pmid19356236 cite journal author Zagouri F, Dimopoulos AM, Fotiou S, Kouloulias V, Papadimitriou CA title Treatment of early uterine sarcomas disentangling adjuvant modalities journal World J Surg Oncol volume 7 issue pages 38 year 2009 pmid 19356236 pmc 2674046 doi 10.1186 1477 7819 7 38 url http www.wjso.com content 7 38 ref If the lesion originates from the stroma of the uterine lining it is an endometrial stromal sarcoma . If the uterine muscle cell is the originator the tumor is a uterine leiomyosarcoma . Classification Uterine sarcoma is staged like endometrial carcinoma at time of surgery using the International Federation of Gynecology and Obstetrics FIGO cancer staging system. Stage IA tumor is limited to the endometrium Stage IB invasion of less than half the myometrium Stage IC invasion of more than half the myometrium Stage IIA endocervical glandular involvement only Stage IIB cervical stromal invasion Stage IIIA tumor invades serosa or adnexa, or malignant peritoneal cytology Stage IIIB vaginal metastasis Stage IIIC metastasis to pelvic or para aortic lymph nodes Stage IVA invasion of the bladder or bowel Stage IVB distant metastasis, including intraabdominal or inguinal lymph nodes Signs and Symptoms Unusual or postmenopausal bleeding may be a sign of a malignancy including uterine sarcoma and needs to be investigated. Other signs include pelvic pain ... test for cervical cancer and not designed to detect uterine sarcoma. Diagnosis Investigations ... sarcoma a debated clinical challenge journal Crit. Rev. Oncol. Hematol. volume 65 issue 2 pages 129 ... Research Foundation Urogenital neoplasia DEFAULTSORT Uterine Sarcoma Category Gynecological cancer Category Sarcoma es Sarcoma uterino ja ... more details
Infobox disease Name Kaposi s sarcoma ICD10 ICD10 C 46 c 45 ICD9 ICD9 176 ICDO ICDO 9140 3 Image Kaposi s Sarcoma.jpg Caption center Papular cutaneous Kaposi s Sarcoma center OMIM 148000 MedlinePlus 000661 ... 7105 MeshID D012514 Kaposi s sarcoma KS is a tumor caused by Kaposi s sarcoma associated herpesvirus Human herpesvirus 8 HHV8 , also known as Kaposi s sarcoma associated herpesvirus KSHV . It was originally ..., Pollack LM, Catania JA, Martin JN title Awareness of Kaposi s Sarcoma Associated Herpesvirus Among ..., Kaposi s sarcoma KS is a systemic disease which can present with cutaneous lesions with or without ... al. Kaposi s sarcoma. N Engl J Med. 2000 342 14 1027 38. ref ref Cattelan AM, et al. Long term clinical outcome of AIDS related Kaposi s sarcoma during highly active antiretroviral therapy. Int J Oncol .... N Engl J Med. 2006 28 355 13 1331 8. ref ref Schwartz RA, et al. Kaposi sarcoma a continuing conundrum ... title Classic Kaposi s sarcoma in Jews living in Israel, 1961 1989 a population based incidence study ... last Fenig first E authorlink coauthors year 1998 month October title Classic Kaposi sarcoma experience ... year 1998 month December title The geographical distribution of Kaposi s sarcoma and of lymphomas ... s sarcoma associated herpesvirus seroprevalence with age in a highly Kaposi s sarcoma endemic ... of human herpesvirus eight with posttransplant Kaposi s sarcoma in Saudi Arabia journal Transplantation ... journal author Beral V, Peterman TA, Berkelman RL, Jaffe HW title Kaposi s sarcoma among persons with AIDS ... Kaposi sarcoma African cutaneous Kaposi sarcoma African lymphadenopathic Kaposi sarcoma AIDS associated Kaposi sarcoma Immunosuppression associated Kaposi sarcoma Signs and symptoms KS lesion s are nodules ... history of AIDS related Kaposi s sarcoma journal Hematol Oncol Clin North Am volume 10 issue 5 ... for the sufferer, and a cause of much psychosocial pathology. Mouth Image Kaposi s sarcoma intraoral AIDS 072 lores.jpg thumb right Intraoral AIDS associated Kaposi sarcoma with an overlying candidiasis ... more details
Infobox disease Name Myeloid sarcoma ICD10 ICD10 C 92 3 c 81 ICD9 ICD9 205.3 ICDO 9930 3 Image Myeloperoxidase.png Caption Myeloperoxidase OMIM MedlinePlus eMedicineSubj eMedicineTopic DiseasesDB MeshID D023981 File Chloroma CMUJ.jpg thumb right Chloroma A myeloid sarcoma chloroma , granulocytic sarcoma , ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref rp 744 extramedullary myeloid tumor , is a solid tumor composed of immature white blood cell s ref name pmid17194660 cite journal author Karlin L, Itti E, Pautas C, et al. title PET imaging as a useful tool for early detection of the relapse site in the management of primary myeloid sarcoma journal Haematologica volume 91 issue 12 Suppl pages ECR54 year 2006 month December pmid 17194660 doi url http www.haematologica.org cgi pmidlookup?view long&pmid 17194660 ref called myeloblast s. A chloroma is an extramedullary manifestation of acute myeloid leukemia in other words, it is a solid collection of leukemic cells occurring outside of the bone marrow . History The condition now known as chloroma was first described by the British people British physician A. Burns ... term granulocytic sarcoma was proposed by Rappaport in 1967 ref Rappaport H. Tumors of the hematopoietic ... sarcoma or chloroma. Specific terms which overlap with granulocytic sarcoma include Leukemia ... granulocytic sarcoma. Meningeal leukemia , or invasion of the subarachnoid space by leukemic ... myeloid sarcoma has been favored. ref name pmid18606981 cite journal author Chevallier P, Mohty M, Lioure B, et al. title Allogeneic Hematopoietic Stem Cell Transplantation for Myeloid Sarcoma A Retrospective ... Byrd JC, Weiss RB. Recurrent granulocytic sarcoma an unusual variation of acute myeloid leukemia ... lymphoma . ref Yamauchi K Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD9 ICDO 8964 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Clear cell sarcoma of the kidney is a rare type of kidney cancer . Clear cell sarcoma can spread from the kidney to other organs, most commonly the bone , but also including the lungs , brain, and soft tissues of the body. Despite the similarities in names, clear cell sarcoma of the kidney is unrelated to clear cell sarcoma . ref Poppe B, Forsyth R, Dhaene K, Speleman F. http atlasgeneticsoncology.org Tumors ClearCellSarcID5074.html Soft tissue tumors Clear cell sarcoma. Atlas Genet Cytogenet Oncol Haematol. November 2002. ref References reflist External links http www.cancer.gov Templates db alpha.aspx?CdrID 44997 Clear cell sarcoma of the kidney entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Soft tissue tumors and sarcomas Urologic neoplasia oncology stub Category Kidney diseases Category Rare cancers Category Types of cancer Category Kidney cancer Category Sarcoma simple Clear cell sarcoma of the kidney ... more details
Infobox Disease Name Langerhans cell sarcoma Image Caption DiseasesDB ICD10 ICD9 ICDO M9756 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D054752 Langerhans cell sarcoma is a form of malignant histiocytosis . It should not be confused with Langerhans cell histiocytosis , which is cytologically benign. ref name Ref MeshName Langerhans Cell Sarcoma ref Langerhans cell sarcoma is known to transform into leukemia. ref name pmid18360746 cite journal author Sumida K, Yoshidomi Y, Koga H, et al. title Leukemic transformation of Langerhans cell sarcoma journal Int. J. Hematol. volume 87 issue 5 pages 527 31 year 2008 month June pmid 18360746 doi 10.1007 s12185 008 0063 x ref It can present in the lung , but such cases are rare. ref name pmid16328350 cite journal author J lg BD, Weidner S, Mayr D title Pulmonary manifestation of a Langerhans cell sarcoma case report and review of the literature journal Virchows Arch. volume 448 issue 3 pages 369 74 year 2006 month March pmid 16328350 doi 10.1007 s00428 005 0115 z ref See also sarcoma References Reflist Histiocytosis Category Sarcoma neoplasm stub ... more details
Infobox disease ICD10 ICD10 C 46 c 45 ICD9 ICD9 176 ICDO ICDO 9140 3 Immunosuppression associated Kaposi sarcoma resembles that of classic Kaposi sarcoma however, the site of presentation is more variable. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 600 See also Kaposi sarcoma Skin lesion References reflist Vascular tumors DEFAULTSORT Immunosuppression Associated Kaposi Sarcoma Category Dermal and subcutaneous growths oncology stub Dermal growth stub ... more details
Infobox Disease Name Mast cell sarcoma Image Caption DiseasesDB ICD10 ICD10 C 96 2 c 81 ICD9 ICD9 202.6 ICDO ICDO 9740 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D012515 Mast cell sarcoma is an extremely aggressive ref cite journal author Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P title Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma journal Am J Surg Pathol volume 27 issue 7 pages 1013 9 year 2003 pmid 12826896 doi 10.1097 00000478 200307000 00019 ref form of sarcoma made up of neoplastic mast cell s. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. Only 3 cases are reported so far. Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern. ref Nancy Gould, Diagnosis and Classification of Mastocytosis , The Mastocytosis Society. http www.tmsforacure.org research consensus.shtml ref Mast cell sarcoma should not be confused with extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as mast cell leukemia one of the most aggressive human cancers. ref Ansell SM editor , Rare Hematological Malignancies Cancer Treatment & Research Series , 1st edition, Springer, 2008. ref See also Mastocytosis References references neoplasm stub Myeloid malignancy Soft tissue tumors and sarcomas Category Dermal and subcutaneous growths Category Sarcoma ... more details
Infobox disease ICD10 ICD10 C 46 0 c 45 ICD9 ICD9 176.0 ICDO ICDO 9140 3 African cutaneous Kaposi sarcoma presents with nodular, infiltrative, vascular masses on the extremities, mostly in men between the ages of 20 and 50, and is endemic in tropical Africa. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 599 See also Kaposi sarcoma Skin lesion References reflist Vascular tumors DEFAULTSORT African Cutaneous Kaposi Sarcoma Category Dermal and subcutaneous growths Oncology stub Dermal growth stub ... more details
Synovial sarcoma, X breakpoint SSX refers to a group of genes associated with synovial sarcoma . ref name pmid16428478 Cite journal author Valmori D, Qian F, Ayyoub M, et al. title Expression of synovial sarcoma X SSX antigens in epithelial ovarian cancer and identification of SSX 4 epitopes recognized by CD4 T cells journal Clin. Cancer Res. volume 12 issue 2 pages 398 404 year 2006 month January pmid 16428478 doi 10.1158 1078 0432.CCR 05 1902 url http clincancerres.aacrjournals.org cgi pmidlookup?view long&pmid 16428478 ref They include SSX1 SSX2 and SSX2B SSX3 gene SSX3 SSX4 gene SSX4 and SSX4B SSX5 SSX6 SSX7 SSX8 SSX9 SSX10 The group also has several associated pseudogene s, and the interacting protein SSX2IP . References Reflist Category Sarcoma Genetics stub ... more details
Orphan date February 2011 Infobox disease Name Epithelioid Sarcoma Like Hemangioendothelioma ICD10 ICD9 ICDO Image Image size 200px Caption OMIM OMIM mult MedlinePlus eMedicineSubj eMedicineTopic DiseasesDB MeshID Epithelioid sarcoma like hemangioendothelioma is an exceedingly rare vascular tumor of intermediate grade that was first described by Steven Billings, Andrew Folpe, and Sharon Weiss in 2003. ref name Billings 2003 http www.ncbi.nlm.nih.gov pubmed 12502927 Billings SD, Folpe AL, Weiss SW. Epithelioid sarcoma like hemangioendothelioma. Am J Surg Pathol. 2003 Jan 27 1 48 57. ref These tumors are so named because their histologic appearance is very similar to that of epithelioid sarcoma , a more malignant tumor with which they are commonly mistaken. References references Uncategorized date February 2011 ... more details
Infobox Disease Name Clear cell sarcoma Image Clear cell sarcoma.Image12.jpg Caption Clear cell sarcoma ... MeshID D018227 Clear cell sarcoma also known as Soft tissue melanoma, and Melanoma of the soft ... cell sarcoma is biologically distinct from melanoma. is a rare form of cancer. ref name pmid17609816 cite journal author Xu GG, Chong YL, Cheong MO title Clear cell sarcoma of the rectus sheath journal ... 4807 4807cr7.pdf ref It is a type of sarcoma . ref name pmid17133413 cite journal author Kawai A, Hosono A, Nakayama R, et al. title Clear cell sarcoma of tendons and aponeuroses a study ... SS, Hayden J, Hornicek F, Mankin HJ title Clear cell sarcoma of soft tissues journal J Surg Oncol volume ... T, Kuo TT, et al. title Clear cell sarcoma of soft tissue a clinicopathologic, immunohistochemical ... 2008 month March pmid 18300804 doi 10.1097 PAS.0b013e31814b18fb url ref Clear cell sarcoma of the soft tissues in adults is not related to the pediatric tumor known as clear cell sarcoma of the kidney ... Soft tissue tumors Clear cell sarcoma. Atlas Genet Cytogenet Oncol Haematol. November ... cells. The clear cell sarcoma has a uniform and distinctive clinical and morphological pattern which serves to distinguish it from other types of sarcoma. Diagnosis Imaging studies such as X rays , computed tomography scans, or MRI may be required to diagnose clear cell sarcoma together with a physical .... ref cite web url http www.mayoclinic.org soft tissue sarcoma diagnosis.html title Diagnosis date ... Clear Cell Sarcoma title Research Notes on Clear Cell Sarcoma date accessdate 2010 ... CCS.htm title Clear Cell Sarcoma of Tendons and Aponeuroses date accessdate 2010 06 29 ref Treatment Treatment depends upon the site and the extent of the disease. Clear cell sarcoma is usually treated ... by radiation and chemotherapy . ref cite web url http www.mayoclinic.org soft tissue sarcoma treatment.html title Treatment date accessdate 2010 06 29 ref See also Melanoma Clear cell sarcoma ... more details
Classic Kaposi sarcoma most commonly appears early on the toes and soles as reddish, violaceous, or bluish black macules and patches that spread and coalesce to form nodules or plaques. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 599 See also Kaposi sarcoma Skin lesion References reflist Dermal growth stub Vascular tumors Category Dermal and subcutaneous growths ... more details
African lymphadenopathic Kaposi sarcoma is aggressive, occurring in children under 10 years of age, presenting with lymph node involvement, with or without skin lesions. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 599 See also Kaposi sarcoma Skin lesion References reflist Dermal growth stub Vascular tumors Category Dermal and subcutaneous growths ... more details
one source date May 2010 Endometrial stromal sarcoma is a rare endometrial tumor arising from the stroma animal tissue stroma connective tissue of the endometrium rather than the glands. There are three grades for endometrial stromal tumors, as follows. ref Sternberg s Diagnostic Surgical Pathology, 5th edition, p. 2242 2245. ref It was previously known as endolymphatic stromal myosis because of diffuse infiltration of myometrium myometrial tissue or the invasion of lymphatic channels ref Kumar V, Abbas A, Fausto N, Aster J 2010 . Robbins and Cotran Pathologic Basis of Disease. 8th edition. Philadelphia Elsevier Saunders ref . Endometrial stromal nodule Image EndometrialStromalNodule.JPG thumbnail right Endometrial Stromal Nodule An endometrial stromal nodule is a noninfiltrative, circumscribed proliferation of endometrial stromal cells . The appearance of the cells is identical to normal stromal cells. This can only be differentiated from low grade sarcoma by confirming lack of infiltration. The differential includes cellular leiomyoma . Diagnosis may be aided by immunostaining endometrial stromal nodules are positive for CD10 leiomyomas are positive for caldesmon and desmin and sometimes CD10 . Low grade endometrial stromal sarcoma Image EndometrialStromalSarcomaLowGrade.JPG thumbnail right Endometrial Stromal Sarcoma, Low Grade Low grade endometrial stromal sarcoma consists of cells resembling normal proliferative phase endometrium, but with infiltration or vascular invasion. These behave more aggressively, sometimes metastasizing, with cancer stage the best predictor of survival. The cells express estrogen progesterone receptors. Undifferentiated uterine sarcoma Image EndometrialStromalSarcoma.JPG thumbnail right Endometrial Stromal Sarcoma, High Grade Undifferentiated uterine sarcoma, or undifferentiated high grade endometrial stromal sarcoma, does not resemble normal ... in endometrial stromal sarcoma. This translocation leads to the fusion of two Polycomb group proteins ... more details
Image Kaposi s sarcoma intraoral AIDS 072 lores.jpg thumb right An HIV positive patient presented with an intraoral Kaposi s sarcoma lesion with an overlying candidiasis infection AIDS associated Kaposi sarcoma or KS AIDS presents with cutaneous lesion s that begin as one or several red to purple red macule s, rapidly progressing to papule s, Nodule dermatology nodule s, and plaque dermatology plaque s, with a predilection for the head, neck, trunk, and mucous membrane s. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 599 KS AIDS simulated the greatest interest as one of the first illnesses associated with AIDS . Different from the classic form of Kaposi sarcoma , KS AIDS tumors usually appear on the head , back , neck , muscular palate and the area of the gingiva . In more advanced cases, they can be found in the stomach and intestines, the lymph nodes, and the lungs. KS AIDS was first described in 1981 by three separate groups, most notably by Robert A. Schwartz and his collaborators at the University of Arizona . ref cite journal title Kaposi s sarcoma presenting in a homosexual man a new and striking phenomenon journal Ariz Med year 1994 first Robert A. last Schwartz coauthors SP Borkovic volume 38 issue 12 pages 902 4 id accessdate 2010 07 29 ref ref cite book last1 Hausen first1 Harald Zur authorlink1 Harald Zur Hausen title Infections Causing Human Cancer chapter Rhadinoviruses publisher Wiley VCH year 2006 location Weinheim accessdate 2010 07 29 ref ref cite book last1 Drabell first1 Fredrick G title New Topics in Cancer Research chapter Kaposi s Sarcoma and Renal Diseases publisher Nova Biomedical Books year 2006 location New York accessdate 2010 07 29 ref See also Kaposi sarcoma Skin lesion List of cutaneous conditions References reflist Category HIV AIDS Category Immune system disorders Category Immunodeficiency Category Infectious diseases ... more details
Taxobox Color parameter is not needed automatically assigned name Rous sarcoma virus virus group vi familia Retroviridae subfamilia Orthoretrovirinae genus Alpharetrovirus species Rous sarcoma virus Rous sarcoma virus is a retrovirus and is the first oncovirus to have been described it causes sarcoma in chickens. As with all retroviruses, it reverse transcribes its RNA genome into cDNA before integration into the host DNA. History RSV was discovered in 1911 by Peyton Rous , working at Rockefeller University in New York City, by injecting cell free extract of chicken tumour into healthy Plymouth Rock chickens. The extract was found to induce oncogenesis . The tumour was found to be composed of connective tissue a sarcoma . Rous was awarded the Nobel Prize for the significance of his discovery in 1966 . Structure and genome RSV is a class VI enveloped virus with a positive sense RNA genome having a DNA intermediate. RSV has three genes gag gene gag encodes capsid proteins pol gene pol encodes reverse transcriptase It lost the env gene normally seen in avian retroviruses during the recombination events that allowed it to acquire src src gene src encodes a tyrosine kinase that attaches ... Secondary structure for the Rous sarcoma stability element. Nucleotide colouring indicates sequence ... element has been identified within the 3 UTR and is known as the Rous Sarcoma Virus Stability Element ... termination codons in the unspliced RNA of Rous sarcoma virus journal RNA volume 12 issue 1 pages ... The RSE element was first identified in the genome of the Rous Sarcoma Virus but appears to be widely ... sarcoma virus RNA stability element journal J. Virol. volume 83 issue 5 pages 2119 29 year ... links http users.rcn.com jkimball.ma.ultranet BiologyPages R RSV.html the Rous sarcoma virus RSV ... molecular expressions at magnet.fsu.edu MeshName Rous sarcoma virus Retroviruses DEFAULTSORT Rous Sarcoma Virus Category Retroviruses de Rous Sarkom Virus fr Virus du Sarcome de Rous ... more details
Infobox Disease Name Follicular dendritic cell sarcoma Image Caption DiseasesDB ICD10 ICD9 ICDO M9758 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D054740 Follicular dendritic cell sarcoma is a form of malignant histiocytosis affecting the follicular dendritic cells . It can present in the nasopharynx . ref name pmid18598838 cite journal author Encabo RS, McHugh J, Carrau RL, Kassam A, Heron D title Follicular dendritic cell sarcoma of the nasopharynx journal Am J Otolaryngol volume 29 issue 4 pages 262 4 year 2008 pmid 18598838 doi 10.1016 j.amjoto.2007.08.005 url http linkinghub.elsevier.com retrieve pii S0196 0709 07 00116 0 ref They can stain positive for CD21 and CD23 . ref name pmid18761751 cite journal author Pisani F, Marino M, Sentinelli S, Petti MC title Follicular dendritic cell sarcoma of the neck report of a case treated by surgical excision and COP plus PEG liposomal doxorubicin journal J. Exp. Clin. Cancer Res. volume 27 issue pages 33 year 2008 pmid 18761751 pmc 2556649 doi 10.1186 1756 9966 27 33 url http www.jeccr.com content 27 33 ref They can also stain positive for CD35 . ref name pmid12393051 cite journal author Nakashima T, Kuratomi Y, Shiratsuchi H, et al. title Follicular dendritic cell sarcoma of the neck a case report and literature review journal Auris Nasus Larynx volume 29 issue 4 pages 401 3 year 2002 month October pmid 12393051 doi 10.1016 S0385 8146 02 00056 1 url http linkinghub.elsevier.com retrieve pii S0385814602000561 ref References reflist Histiocytosis Category Monocyte and macrophage related cutaneous conditions disease stub ... more details
Spindle cell sarcoma is a type of connective tissue cancer in which the cells are spindle shaped when examined under a microscope . The tumors generally begin in layers of connective tissue such as that under the skin, between muscles, and surrounding organs, and will generally start as a small lump with inflammation that grows. At first the lump will be self contained as the tumor exists in its stage 1 state, and will not necessarily expand beyond its encapsulated form. However, it may develop cancerous processes that can only be detected through microscopic examination. As such, at this level the tumor is usually treated by excision that includes wide margins of healthy looking tissue, followed by thorough biopsy and additional excision if necessary. The prognosis for a stage 1 tumor excision is usually fairly positive, but if the tumors progress to levels 2 and 3, prognosis is worse because tumor cells have likely spread to other locations. These locations can either be nearby tissues or system wide locations that include the lungs, kidneys, and liver. In these cases prognosis is grim and chemotherapy and radiation are the only methods of controlling the cancer. Spindle cell sarcoma can develop for a variety of reasons, including genetic predisposition but it also may be caused by a combination of other factors including injury and inflammation in patients that are already thought to be predisposed to such tumors. Spindle cells are a naturally occurring part of the body s response to injury. When cells divide they form into a spindle shape as part of mitosis, and spindle cell tumors are just masses of these cells that are stuck in this form. In response to an injury, infection, or other immune response the connective tissues will begin dividing to heal the affected area ...?CdrID 44298 Spindle cell sarcoma entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Sarcoma Oncology stub ... more details
Infobox Disease Name Interdigitating dendritic cell sarcoma Image Caption DiseasesDB ICD10 ICD9 ICDO M9757 3 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D054739 Interdigitating dendritic cell sarcoma is a form of malignant histiocytosis affecting dendritic cell s. It can present in the spleen . ref name pmid11914634 cite journal author Kawachi K, Nakatani Y, Inayama Y, Kawano N, Toda N, Misugi K title Interdigitating dendritic cell sarcoma of the spleen report of a case with a review of the literature journal Am. J. Surg. Pathol. volume 26 issue 4 pages 530 7 year 2002 month April pmid 11914634 doi 10.1097 00000478 200204000 00018 url http meta.wkhealth.com pt pt core template journal lwwgateway media landingpage.htm?issn 0147 5185&volume 26&issue 4&spage 530 ref It can also present in the duodenum . ref name pmid16454564 cite journal author Kanaan H, Al Maghrabi J, Linjawi A, Al Abbassi A, Dandan A, Haider AR title Interdigitating dendritic cell sarcoma of the duodenum with rapidly fatal course a case report and review of the literature journal Arch. Pathol. Lab. Med. volume 130 issue 2 pages 205 8 year 2006 month February pmid 16454564 doi url http journals.allenpress.com jrnlserv ?request get abstract&issn 0003 9985&volume 130&page 205 ref References reflist Histiocytosis Category Lymphoid related cutaneous conditions neoplasm stub ... more details
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