PBB geneid 6139 60S ribosomal protein L17 is a protein that in humans is encoded by the RPL17 gene . ref name pmid2402465 cite journal author Mager DL, Freeman JD title A human gene related to the ribosomal protein L23 gene of Halobacterium marismortui journal Nucleic Acids Res volume 18 issue 17 pages 5301 year 1990 month Oct pmid 2402465 pmc 332174 doi 10.1093 nar 18.17.5301 ref ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name entrez cite web title Entrez Gene RPL17 ribosomal protein L17 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6139 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui however, its official symbol is RPL17. Two alternative splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. ref name entrez References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Wool IG, Chan YL, Gl ck A title Structure and evolution of mammalian ribosomal proteins ... more details
Rfam box acc RF00151 description Small nucleolar RNA SNORD58 abbreviation SNORD58 avg length 65.70 avg identity 77.00 type Gene snRNA snoRNA CD box se Griffiths Jones SR ss Predicted PFOLD release 10.0 snoRNA U58 also known as SNORD58 is a non coding RNA ncRNA molecule which functions in the modification of other small nuclear RNA s snRNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a snoRNA small nucleolar RNA snoRNA and also often referred to as a guide RNA. snoRNA U57 belongs to the SnoRNA C.2FD box C D box class of snoRNAs which contain the conserved sequence motifs known as the C box UGAUGA and the D box CUGA . Most of the members of the box C D family function in directing site specific 2 O methylation of substrate RNAs ref cite journal last Galardi first S coauthors Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I year 2002 title Purified box C D snoRNPs are able to reproduce site specific 2 O methylation of target RNA in vitro journal Mol Cell Biol volume 22 pages 6663&ndash 6668 pmid 12215523 doi 10.1128 MCB.22.19.6663 6668.2002 issue 19 pmc 134041 ref . In the human genome there are two closely related copies of U85 called U58A and U58B . They are both encoded in the introns of the ribosomal protein RPL17 gene. Both snoRNAs are predicted to guide 2 O ribose methylation of the large 28S ribosomal RNA rRNA subunit on residue G4198 ref name pmid8674114 cite journal author Kiss L szl Z, Henry Y, Bachellerie JP, Caizergues Ferrer M, Kiss T title Site specific ribose methylation of preribosomal RNA a novel function for small nucleolar RNAs journal Cell volume 85 issue 7 pages 1077 88 year 1996 pmid 8674114 doi 10.1016 S0092 8674 00 81308 2 ref . References reflist External links Rfam id RF00151 name Small nucleolar RNA SNORD58 http www snorna.biotoul.fr plus.php?id U58A snoRNABase entry for SNORD58A http www snorna.biotoul.fr plus.php?id U58B snoRNABase ent ... more details
PBB geneid 9349 60S ribosomal protein L23 is a protein that in humans is encoded by the RPL23 gene . ref name pmid1861993 cite journal author Herault Y, Michel D, Chatelain G, Brun G title cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17 journal Nucleic Acids Res volume 19 issue 14 pages 4001 year 1991 month Aug pmid 1861993 pmc 328500 doi 10.1093 nar 19.14.4001 ref ref name entrez cite web title Entrez Gene RPL23 ribosomal protein L23 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 9349 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. ref name entrez References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Wool IG, Chan YL, Gl ck A title Structure and evolution of mammalian ribosomal proteins. journal Biochem. Cell Biol. volume 73 issue 11 12 pages 933 47 year 1996 pmid 8722009 doi 10.1139 o95 101 cite journal author Berchtold MW, Berger MC title Isolation and analysis of a human cDNA highly homologous to the yeast gene encoding L17A ribosomal protein. journal Gene volume 102 issue 2 pages 283 8 year 1991 pmid 1874450 doi ... more details
PBB geneid 6206 40S ribosomal protein S12 is a protein that in humans is encoded by the RPS12 gene . ref name pmid1861993 cite journal author Herault Y, Michel D, Chatelain G, Brun G title cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17 journal Nucleic Acids Res volume 19 issue 14 pages 4001 year 1991 month Aug pmid 1861993 pmc 328500 doi 10.1093 nar 19.14.4001 ref ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name entrez cite web title Entrez Gene RPS12 ribosomal protein S12 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6206 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. ref name entrez References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Wool IG, Chan YL, Gl ck A title Structure and evolution of mammalian ribosomal proteins. journal Biochem. Cell Biol. volume 73 issue 11 12 pages 933 47 year 1996 pmid 8722009 doi 10.1139 o95 101 cite journal autho ... more details
Encyclopedia
top
