PBB geneid 6135 60S ribosomal protein L11 is a protein that in humans is encoded by the RPL11 gene . ref name pmid9582194 cite journal author Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC title A map of 75 human ribosomal protein genes journal Genome Res volume 8 issue 5 pages 509 23 year 1998 month Aug pmid 9582194 pmc doi 10.1101 gr.8.5.509 ref ref name pmid10343117 cite journal author Graphodatsky AS, Vorobieva NV, Filipenko ML, Voronina EV, Frengen E, Prydz H title Assignment of the L11 ribosomal protein gene RPL11 to human chromosome 1p36.1 p35 by in situ hybridization journal Cytogenet Cell Genet volume 84 issue 1 2 pages 97 8 year 1999 month Jun pmid 10343117 pmc doi 10.1159 000015228 ref ref name entrez cite web title Entrez Gene RPL11 ribosomal protein L11 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 6135 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternative splice variants encoding different isoforms may exist, but they have not been fully characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. ref name entrez Interactions RPL11 has been shown to Protein protein interaction interact with P16 gene P16 , ref name pmid14612427 cite journal ... summary yes update citations yes gene 1 stub es RPL11 ... more details
Letter NumberCombination L10 L12 K11 M11 L11 or L 11 may refer to Military Little Boy , codenamed L11 by the US military, is the name of the atomic bomb dropped on Hiroshima USS L 11 SS 51 , a United States Navy submarine which saw service in World War I HMS L11 , a Royal Navy submarine which saw service during World War I HMS Intrepid L11 , a Royal Navy amphibious assault craft which saw service during the Falklands War M2 Browning machine gun , British Army s designation for the M 2 heavy machine gun L 11 76.2 mm tank gun , Soviet tank gun mounted on early T 34 tank s. Commercial Products Coolpix L11 , a model of digital camera manufactured by Nikon LSWR L11 Class , a model of steam locomotive manufactured by London and South Western Railway Other RPL11 , the human gene named ribosomal protein L11 Barcelona Metro line 11 , a stop on the Barcelona, Spain public transportation train route Letter NumberCombDisambig de L11 ... more details
for the band and album of the same name P53 band P53 album lowercase PBB geneid 7157 p53 also known as protein 53 or tumor protein 53 , is a tumor suppressor protein that in humans is encoded by the TP53 gene. ref name pmid6396087 cite journal author Matlashewski G, Lamb P, Pim D, Peacock J, Crawford L, Benchimol S title Isolation and characterization of a human p53 cDNA clone expression of the human p53 gene journal EMBO J. volume 3 issue 13 pages 3257 62 year 1984 month December pmid 6396087 pmc 557846 doi url issn ref ref name pmid3456488 cite journal author Isobe M, Emanuel BS, Givol D, Oren M, Croce CM title Localization of gene for human p53 tumour antigen to band 17p13 journal Nature volume 320 issue 6057 pages 84 5 year 1986 pmid 3456488 doi 10.1038 320084a0 url ref ref name pmid2047879 cite journal author Kern SE, Kinzler KW, Bruskin A, Jarosz D, Friedman P, Prives C, Vogelstein B title Identification of p53 as a sequence specific DNA binding protein journal Science journal volume 252 issue 5013 pages 1708 11 year 1991 month June pmid 2047879 doi 10.1126 science.2047879 url issn ref ref name pmid 3001719 cite journal author McBride OW, Merry D, Givol D title The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm 17p13 journal Proc. Natl. Acad. Sci. U.S.A. volume 83 issue 1 pages 130 134 year 1986 pmid 3001719 pmc 322805 doi 10.1073 pnas.83.1.130 url ref p53 is important in multicellular organism s, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer . As such, p53 has been described as the guardian of the genome , the guardian angel gene , and the master watchman , referring to its role in conserving stability by preventing genome mutation. ref name isbn0 471 33061 2 cite book author Read, A. P. Strachan, T. title Human molecular genetics 2 publisher Wiley location New York year 1999 pages lala lala isbn 0 471 33061 2 oclc doi chapter Chapter 18 Cancer Genetics ref T ... more details
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