to punicalagins, the marker compound of pomegranate. Extracts of pomegranate are also ... normalized to punicalagins. ref Seeram et al. J Nutr Biochemistry 2005 16 360 367. ref A pomegranate extract standardized to punicalagins marketed under the name Pomella was found to absorb into the bloodstream .... J Agric Food Chem. 2006 Nov 15 54 23 8956 8961 ref Plants As the chemistry of punicalagins became known it was found to be not unique to pomegranate. Punicalagins are present in numerous species of the genus ... more details
chembox verifiedrevid 400996763 Name Punicalagin alpha ImageFile Alpha punicalagin.png ImageSize 200px ImageName Chemical structure of punicalagin alpha IUPACName OtherNames 1 alpha O galloylpunicalagin br Section1 Chembox Identifiers CASNo CASNo Ref CASOther PubChem SMILES InChI MeSHName Section2 Chembox Properties Formula C sub 55 sub H sub 32 sub O sub 34 sub MolarMass 1236.82 g mol ExactMass 1236.077498 u Appearance Density MeltingPt C BoilingPt C Solubility Punicalagin alpha is a punicalagin , a type of hydrolysable tannins. A study in Taiwan showed that punicalagin alpha 1 alpha O galloylpunicalagin induced nitric oxide production in a dose dependent manner in endothelial cells ref http www.ncbi.nlm.nih.gov pubmed 18435486 Tannin 1 alpha O galloylpunicalagin induces the calcium dependent activation of endothelial nitric oxide synthase via the phosphatidylinositol 3 kinase Akt pathway in endothelial cells. ref as well as inhibited Extracellular signal regulated kinases ERK , c Jun N terminal kinases JNK and Akt , all of which play roles in cancer growth, so their inhibition points to punicalagins potential as strong cancer suppressors. Fact date February 2009 References reflist hydrolysable tannin category tannins Category Pyrogallols Category Benzoates Natural phenol stub ... more details
chembox verifiedrevid 414204628 Name Gallagic acid ImageFile Gallagic acid.PNG ImageSize 200px ImageName Chemical structure of gallagic acid IUPACName OtherNames br Section1 Chembox Identifiers CASNo 65995 62 2 CASNo Ref CASOther PubChem SMILES Oc4c6c1c c5c O o6 c oc O c1c c4O c c O c2O c C O O cc2O c O c O c5 c3c C O O cc O c O c3O InChI MeSHName Section2 Chembox Properties Formula C sub 28 sub H sub 14 sub O sub 18 sub MolarMass 638.39 g mol ExactMass 638.018013 u Appearance Density MeltingPt C BoilingPt C Solubility Gallagic acid is a polyphenolic chemical compound that can be found in the ellagitannins, a type of tannin, found in Punica granatum pomegranate ref http cat.inist.fr ?aModele afficheN&cpsidt 18773247 Antioxidant, antimalarial and antimicrobial activities of tannin rich fractions, ellagitannins and phenolic acids from Punica granatum L. Reddy Muntha K., Gupta Sashi K., Jacob Melissa R., Khan Shabana I. and Ferreira Daneel, Planta medica, 2007, vol. 73, no5, pp. 461 467 ref . It is a building block of the corresponding tannin punicalagins , punicalin , punicacortein C and 2 O galloyl punicalin . References reflist hydrolysable tannin category tannins Category Pyrogallols Category Chromenochromenes Category Trihydroxybenzoic acids Category Lactones Natural phenol stub ... more details
tannins. The most abundant of pomegranate tannins are called punicalagins . Punicalagins have ... to show no toxic effects in rats who were given a 6 diet of punicalagins for 37 days. ref cite journal ... ref Punicalagins are also found to be the major component responsible for pomegranate juice s antioxidant ... are available that contain extracts of whole pomegranate and or are standardized to punicalagins ... normalized to punicalagins. ref cite journal author Seeram NP, Adams LS, Henning SM, et al ... more details
tannins called ellagitannin s formed when ellagic acid binds with a carbohydrate . Punicalagins are tannins ... 269 issue 2 pages 262 8 date October 8, 2008 pmid 18468784 doi 10.1016 j.canlet.2008.03.043 ref Punicalagins ... ref During intestinal metabolism by bacteria, ellagitannins and punicalagins are converted to urolithins ... more details
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