File Hox cluster.svg thumb 300px Do not even bother vandalizing this page. homoerotic genes is not funny. and can be reverted with a click Hox genes are a group of related gene s that determine the basic structure and orientation of an organism. ref Dictionary.com Hox gene http dictionary.reference.com browse Hox gene . Accessed March 31, 2011. ref Hox genes are critical for the proper placement of Segmentation ..., and wings in fruit flies or the different vertebrate ribs in humans . Hox genes are defined ... of their genes within the Hox gene cluster. ref cite journal author Carroll S. B. coauthors year ... . Hox proteins The protein products of Hox genes are the Hox proteins. Hox proteins are transcription ... genetics enhancers where they either activate or repress genes. The same Hox protein can act as a repressor ... product of the Hox gene Antennapedia activates genes that specify the structures of the 2nd ..., will form wherever the Antennapedia protein is located. The ability of Hox proteins to bind ..., homeodomains of individual Hox proteins usually exhibit greater similarity to homeodomains in other species than to proteins encoded by adjacent genes within their own Hox cluster. These two observations led to the suggestions that Hox gene clusters evolved from a single Hox gene via tandem duplication and subsequent divergence and that a prototypic Hox gene cluster containing at least seven different Hox genes was present in the common ancestor of all bilatrian animals bilaterian animals ... 1346368 volume 68 issue 2 pages 283 302 doi 10.1016 0092 8674 92 90471 N ref Classification of Hox ... degree of functional similarity, e.g. Hox proteins with identical homeodomains are assumed to have ..., classification schemes are used. For Hox proteins, three different classification schemes exist ... Hueber S.D. coauthors Weiller G.F., Djordjevic, M. A, Frickey, T. year 2010 title Improving Hox ... doi ref The functional equivalence of such a set of Hox proteins can be demonstrated by the fact that a fly ... more details
Archibald Hoxsey trading card circa 1920 Notes Image Caption Arch Hoxsey. In Cigarette cards Champion athletes Library Division Humanities and Social Sciences Library George Arents Collection Subject s Cigarette cards Notes Several hundred A.T.C. group issues America. Collection Guide Cigarette Cards ABCs Digital Image ID 1205490 Digital Record ID 480750 NYPL Call Number Arents Cigarette Cards PD US Source New York Public Library http digitalgallery.nypl.org nypldigital dgdisplaylargemeta.cfm?strucID 480750&imageID 1205491&parent id 1016645&word &s ¬word &d &c &f &sScope &sLevel &sLabel &lword &lfield &num 0&imgs 12&total 12&pos 7&snum &dup yes ... more details
early childhood cancer at a higher rate than the general population ref name debate hox cancer cite web title Debate on Vertebral variation, Hox genes, development, and cancer url http scienceblogs.com pharyngula 2006 01 vertebral variation hox genes.php comment 1157189 author Myers, PZ accessdate 2008 04 16 ref ref name hox cancer cite web title Vertebral variation, Hox genes, development, and cancer url http scienceblogs.com pharyngula 2006 01 vertebral variation hox genes.php author Myers, PZ accessdate 2008 04 16 ref . The Hox gene Hox genes that control the development of cervical vertebrae are believed to play a role in suppressing cancer. ref name hox cancer In other vertebrates Many ... more details
The Cdx protein family is a group of the transcription factor proteins which bind to DNA to regulate the expression of genes. ref M. B land & al. Cdx1 autoregulation is governed by a novel Cdx1 LEF1 transcription complex , Molecular and Cellular Biology 24, 5028 5038, 2004. ref In particular this family of proteins can regulate the Hox genes . Cdx proteins Cdx1 protein Cdx2 protein Cdx4 protein The human Cdx2 family protein has 94 identity with the mouse Cdx2 and the hamster Cdx3. ref G. V. Mallo & al. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis , Int. J. Cancer. 74, 35 44, 1997. ref Cdx proteins and regulation of Hox gene expression Cdx proteins are key regulatiors of Hox genes . The vertebrate Cdx proteins act Upstream and downstream DNA upstream of Hox genes. Cdx genes integrate the posteriorizing Signal physiology signals from retionic acic and Wnt canonical pathways and relay this information to Hox Promoter biology promoter s. ref D. Lohnes. The Cdx1 homeodomain protein an integrator of posterior Signal physiology signaling in the mouse , Bioessays 25, 971 980, 2003. ref Expression in mouse embryo Cdx2 expression begins at 3.5 days and is confined to the throphectoderm, being absent from the inner cell mass. From 8.5 days, Cdx2 begins to be expressed in embryonic tissues, principally in the posterion part of the gut from its earliest formation. ref F. Beck. Expression of Cdx 2 in the mouse embryo and placenta possible role in patterning of the extra embryonic membranes , Developmental Dynamics 204, 219 227, 1995. ref See also Protein Protein family transcription factor Neural tube References reflist External links Category Proteins Category Protein families ar de Cdx Proteine fa fr Prot ines Cdx ... more details
Other persons William McGinnis William Bill McGinnis , Doctor of Philosophy Ph.D. is a molecular biology molecular biologist and professor of biology at the University of California, San Diego UCSD . At UCSD he has also served as the Chairman of the Department of Biology from July 1998 June 1999, as Associate Dean of the Division of Natural Sciences from July 1, 1999 June 2000, and as Interim Dean of the newly established Division of Biological Sciences from July 1, 2000 February 1, 2001. He received his Ph.D. from UC Berkeley in 1982 and was a Jane Coffin Childs Memorial Fund for Medical Research Jane Coffin Childs postdoctoral fellow at the University of Basel . From 1984 to 1995, he was on the faculty of Yale University . He received a Searle Scholar Award, a Presidential Young Investigator Award, and a Dreyfuss Teacher Scholar Award. Research McGinnis studies the evolutionary changes in transcription factor s by looking at the Hox genes. His main research has been in Drosophila , comparing Hox genes within that species with Hox genes in other species, to see they are conserved kept intact during evolution. He also studies how Hox transcription functions control morphogenesis , and how changes in the Hox proteins, cofactors, and DNA targets affect morphology biology morphology . One long term objective of the research in his lab is to understand the molecular interactions that underlie functional specificity in the Hox patterning system. Publications McGinnis has published in Science journal Science , Oxford University Press , Nature journal Nature , http embojournal.npgjournals.com EMBO Journal , and http www.ajhg.org journal The American Journal of Human Genetics . Articles cite journal last McGinnis first William authorlink coauthors Michael Kuziora year 1994 month February day title The Molecular Architects of Body Design journal Scientific American volume 270 issue 2 pages 36 42 External links http www.biology.ucsd.edu labs mcginnis McGinnis Lab University o ... more details
Orphan date November 2006 The ParaHox gene cluster is an array of homeobox genes, cousins of the Hox gene s. The cluster is composed of the genes CDX1 Cdx1 , CDX2 Cdx2 , CDX4 Cdx4 , GHX1 Gsx1 and GSX2 Gsx2 . References http www.ncbi.nlm.nih.gov entrez query.fcgi?cmd Retrieve&db PubMed&list uids 9582071&dopt Citation Category Genes Cell biology stub ... more details
Orphan date October 2008 Gonadogenesis is one of the many particular stages organogenesis . As the body develops from a single celled zygote into a fetus , and eventually a baby, many steps are taken in an effort to promote cell differentiation and specialization. Gonadogenesis refers to the more specific changing of cells into a uterus in females or a vas deferens in males. Gonadogenesis is not fully understood, however, the importance of the GON 4 gene is apparent. Additional HOX genes are factors as well. External links http www.biochem.wisc.edu kimble publications pdfs 2000s 089 99 98 friedman et al db 2000.pdf search gonadogenesis www.biochem.wisc.edu on Gonadogenesis Category Developmental biology Category Embryology developmental biology stub ... more details
in Canada Hox Category French language radio stations in Quebec Hox Category Radio stations in Bas Saint Laurent Hox Category Groupe Radio Simard radio stations Hox Quebec radio station stub ... more details
Homeotic genes are gene s that determine which parts of the body form what body parts. One example are the Hox gene Hox and ParaHox genes which are important for segmentation biology segmentation , ref cite journal author Young T, Rowland JE, van de Ven C, et al. title Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos journal Dev. Cell volume 17 issue 4 pages 516 26 year 2009 month October pmid 19853565 doi 10.1016 j.devcel.2009.08.010 ref another example is the MADS box containing genes in the ABC model of flower development . ref cite journal author Theissen G title Development of floral organ identity stories from the MADS house journal Curr. Opin. Plant Biol. volume 4 issue 1 pages 75 85 year 2001 pmid 11163172 url http linkinghub.elsevier.com retrieve pii S1369 5266 00 00139 4 doi 10.1016 S1369 5266 00 00139 4 ref See also Homeobox Homeotic genes are genes involved in developmental patterns and sequences. For example, homeotic genes are involved in determining where, when, and how body segments develop in flies. Alterations in these genes cause changes in patterns of body parts, sometimes causing dramatic effects such as legs growing in place of antennae or an extra set of wings or, in the case of plants, flowers with abnormal numbers of parts. An individual carrying an altered mutant version of a homeotic gene is known as a homeotic mutant. Homeotic selector gene References Reflist 2 developmental biology stub Category Genetics Category Developmental biology it Omeogene ... more details
the early Cambrian. The same study also found that Hox genes diversified long before these groups ... Hox genes in brachiopods and priapulids and protostome evolution. pmid 10391241 last2 Grenier first2 ... more details
are encoded both by genes of the Hox gene Hox gene clusters and by other genes throughout the genome ... journal Trends Neurosci. volume 10 issue pages 3 6 year 1987 ref Hox genes encode homeodomain containing ... axis of animal bodies. ref name PUB00010002 cite journal author Alonso CR title Hox proteins sculpting ... binding proteins the requirement is relaxed. Hox genes This section is linked from Snake File Hoxgenesoffruitfly.svg Homeobox gene expression in Drosophila melanogaster . thumb right 400px Main Hox gene ... posterior axis. The first vertebrate Hox gene was isolated in Xenopus by Eddy De Robertis and colleagues ... that some limited number of Hox genes have existed in the Cnidaria since before the earliest true ... R. Finnertyl title Pre Bilaterian Origins of the Hox Cluster and the Hox Code Evidence from the Sea ... homeotic genes in plants MADS box genes are not homology biology homologous to Hox genes in animals ... Hox genes in four clusters class wikitable name chromosome gene HOXA or sometimes HOX1 Gene HOXA chromosome ... been important in the evolution of segmented animals. However, Hox genes typically determine the identity ... of Hox genes is highly complex and involves reciprocal interactions, mostly inhibitory. Drosophila ... of Hox genes after the down regulation of the pair rule and gap genes that occurs during larval development. Polycomb group proteins can silence the HOX genes by modulation of chromatin structure ... H title Missing link in the evolution of Hox clusters journal Gene volume 387 issue 1 2 pages 21 ... more details
. Zoological Science, 22, 2001 ref The draft genome analysis identified nine Hox gene s, which are Ci ... al. 2003. Unusual number and genomic organization of Hox genes in the tunicate Ciona intestinalis. Gene ... set of Hox genes. The organization of Hox genes is only known for C. intestinalis among ascidians. The nine Hox genes are located on two chromosomes Ci Hox1 to 10 on one chromosome and Ci Hox12 and 13 on another. The intergenic distances within the Ciona Hox genes are extraordinarily long. Seven Hox ... comparisons to the Hox gene expressions and locations in other species, it is likely that the ascidian ... of Hox genes in ascidians Present, past, and future. Developmental Dynamics 233.2 2005 382 89. ref ... more details
PBB geneid 100302299 HOTAIRM1 HOX antisense intergenic RNA myeloid 1 is a long non coding RNA gene. In humans, it is located between the HOXA1 and HOXA2 genes. HOTAIRM1 is expressed in cells of a myeloid lineage, and may play a role in myeloid transcriptional regulation . ref name pmid19144990 cite journal author Zhang X, Lian Z, Padden C, et al. title A myelopoiesis associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster journal Blood volume 113 issue 11 pages 2526 34 year 2009 month March pmid 19144990 pmc 2656274 doi 10.1182 blood 2008 06 162164 url ref See also Long noncoding RNA References reflist Category Non coding RNA ... more details
File Trilobite sections en.svg thumb The tagmata of a trilobite cephalon, thorax and pygidium In invertebrate biology , a tagma plural tagmata is a specialized grouping of arthropod segmentation biology segment s, such as the head, the thorax , and the abdomen with a common function. ref cite book author D. R. Khanna year 2004 title Biology of Arthropoda publisher Discovery Publishing House isbn 9788171418978 url http books.google.co.uk books?id Hd4OEDo4gbwC ref The segments of a tagma may be either fused or moveable. Tagmata Tagma divisions vary among taxa . For example, in trilobite s the tagmata are the cephalon arthropod anatomy cephalon head , thorax body , and Trilobite Terminology pygidium tail , whereas in Hexapoda hexapods , these same divisions are called head , thorax, and abdomen. The body of spider s and some crustacean s is divided into two tagmata the cephalothorax and the opisthosoma spiders or abdomen crustaceans . Tagmosis The evolution ary process that creates tagmata by fusing and modifying segments is called tagmosis , which is an extreme form of wikt heteronomous heteronomy , mediated by Hox gene Hox genes and the other developmental genes they influence. ref cite book author Alessandro Minelli year 2003 title The development of animal form ontogeny, morphology, and evolution publisher Cambridge University Press isbn 9780521808514 chapter Body Regions Their Boundaries and Complexity pages 79 105 url http books.google.co.uk books?id ThzSi5bMDE0C&pg PA85 ref References reflist DEFAULTSORT Tagma Biology Category Arthropod anatomy de Tagma Anatomie es Tagma eu Tagma no Tagma nn Tagmose pl Tagmy pt Tagma ro Tagm ru ... more details
italic title Taxobox name Oikopleura image Oikopleura.jpg image width 250px image caption Oikopleura dioica regnum Animal ia phylum Chordata subphylum Urochordata classis Appendicularia ordo Copelata familia Oikopleuridae genus Oikopleura genus authority Lohmann, 1896 subdivision ranks Species subdivision Oikopleura dioica br Oikopleura fusiformis br Oikopleura labradoriensis br Oikopleura vanhoeffeni Oikopleura is a genus of Urochordata urochordates sea squirts in the class Appendicularia . It forms a mucus house every four hours at 20 degrees Celsius. This house has a coarse mesh to keep out big particles, and a fine mesh that collects the small particles, down to the nanoplankton that includes pelagic bacteria . Abandoned mucus houses sink to the deep, collecting organic particles during their descent. They make an important contribution to marine snow , since Oikopleura is abundant and is a very active filterer, using powerful strokes of its tail. Its abundance is less obvious from preserved samples that are usually analyzed because the gelatinous body disappears in the preservation process while leaving hardly any trace. It has only about 15,000 genes. Oikopleura dioica A species of particular interest under this genus is the Oikopleura dioica , which is an anomaly among chordates . It has retained the fundamental body plan of the chordate yet, it has lost the mechanism for retinoic acid signaling which operates during chordate development. The loss raises the question of the evolutionary constraints that have prevented similar changes in the other chordates. ref Holland, Linda Z. Developmental biology A chordate with a difference. Nature 447.1 2007 153 55. ref Oikopleura dioica hox genes are distributed in nine locations around the genome whereas other chordate s have a cluster of hox genes. Nature 2 Sept 2004 References reflist Category Tunicates ... more details
PBB geneid 3206 Homeobox protein Hox A10 is a protein that in humans is encoded by the HOXA10 gene . ref name pmid1973146 cite journal author McAlpine PJ, Shows TB title Nomenclature for human homeobox genes journal Genomics volume 7 issue 3 pages 460 year 1990 month Aug pmid 1973146 pmc doi 10.1016 0888 7543 90 90186 X ref ref name pmid1358459 cite journal author Scott MP title Vertebrate homeobox gene nomenclature journal Cell volume 71 issue 4 pages 551 3 year 1992 month Dec pmid 1358459 pmc doi 10.1016 0092 8674 92 90588 4 ref ref name entrez cite web title Entrez Gene HOXA10 homeobox A10 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 3206 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic ... author Eun Kwon H, Taylor HS title The role of HOX genes in human implantation. journal Ann. N. Y ... journal author Lowney P, Corral J, Detmer K, et al. title A human Hox 1 homeobox gene exhibits myeloid ... author Acampora D, D Esposito M, Faiella A, et al. title The human HOX gene family. journal Nucleic ... journal author Apiou F, Flagiello D, Cillo C, et al. title Fine mapping of human HOX gene clusters ... Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. journal Mol. Cell. Biol. volume ... Heuvel GB, Igarashi P title A conserved Hox axis in the mouse and human female reproductive system ... H, Humphries RK, Blair A, et al. title Expression of HOX genes, HOX cofactors, and MLL in phenotypically ... differential tissue specific regulation of HOX gene expression in the reproductive tract. journal J ... cite journal author Shen WF, Krishnan K, Lawrence HJ, Largman C title The HOX homeodomain proteins ... more details
program shifted towards the molecular evolution of developmental genes, initially Hox gene s and Hox ... in the intergenic regions between Hox genes, ref Chiu, C. h., C. Amemiya, K. Dewar, C. b. Kim ... lineages. PNAS 99 5492 5497. ref and dated the fish specific Hox cluster duplication to nearly .... J. Lynch, C. Amemiya, and G. P. Wagner. 2006. The Fish Specific Hox Cluster Duplication Is Coincident with the Origin of Teleosts. Mol Biol Evol 23 121 136. ref This work led to the theory that Hox cluster ..., and F. Ruddle. 2003. Hox cluster duplications and the opportunity for evolutionary novelties ... more details
Unreferenced date May 2009 Image Kingston CitiBus 052.jpg thumb A Dupont Trolley Champlain 1608 bus in Kingston, New York Kingston, NY . Dupont Industries, Inc. is a company specializing in the manufacture and rebuilding of buses. Based in Quebec City , it has been in business for over 60 years. Most of Dupont s clients are in Canada and the United States . Products Victoria based on General Motors Diesel Division Buses Rapid Transit Series RTS rebuild Cartier based on General Motors Diesel Division Buses GMDD Motor Coach Industries MCI Nova Bus Classic transit bus Classic rebuild Thomas Dennis Company LLC Frontenac 1672 trolley bus Thomas Built Buses, Inc. Thomas HOX Champlain 1608 trolley bus Thomas Built Buses, Inc. Thomas MVP EF Champlain 1608 low floor CNG trolley bus External links http www.dupontrolley.com Dupont Industries, Inc. official web site References reflist North American bus builders Category Bus manufacturers Category Manufacturing companies of Canada Category Motor vehicle manufacturers of Canada Category Companies based in Quebec City Category Motor vehicle assembly plants in Canada ... more details
PBB geneid 3231 Homeobox protein Hox D1 is a protein that in humans is encoded by the HOXD1 gene . ref name pmid1973146 cite journal author McAlpine PJ, Shows TB title Nomenclature for human homeobox genes journal Genomics volume 7 issue 3 pages 460 year 1990 month Aug pmid 1973146 pmc doi 10.1016 0888 7543 90 90186 X ref ref name pmid1358459 cite journal author Scott MP title Vertebrate homeobox gene nomenclature journal Cell volume 71 issue 4 pages 551 3 year 1992 month Dec pmid 1358459 pmc doi 10.1016 0092 8674 92 90588 4 ref ref name entrez cite web title Entrez Gene HOXD1 homeobox D1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 3231 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA binding domain. This nuclear protein functions as a sequence specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior posterior a p limb axis. ref name entrez See also Homeobox References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Boncinelli E, Acampora D, Pannese M, et al. title Organization of human class I homeobox genes. journal Genome volume 31 issue 2 pages 745 56 year 1990 pmid 2576652 doi cite journal author Manohar CF, Salwen HR, Furtado MR, Cohn SL title Up regulation of HOXC6 ... transcription factor 1 gene is a candidate target for regulation by Hox proteins. journal EMBO J. volume ..., Furtado MR, Salwen HR, Cohn SL title Hox gene expression in differentiating human neuroblastoma cells ... B, Sood R, Ott S, et al. title Isolation and characterization of the human homeobox gene HOX ... of the 39 human HOX genes. journal Teratology volume 65 issue 2 pages 50 62 year 2002 pmid 11857506 ... more details
sub 5 sub sub 1 sub is an integrin that binds to matrix macromolecules and proteinase s and thereby stimulates angiogenesis . ref name pmid14610084 cite journal author Boudreau NJ, Varner JA title The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis journal J. Biol. Chem. volume 279 issue 6 pages 4862 8 year 2004 month February pmid 14610084 doi 10.1074 jbc.M305190200 url issn ref It is composed of sub 5 sub ITGA5 CD49e and sub 1 sub CD29 ITGB1 CD29 subunits. It is the primary receptor for fibronectin. The interaction of VLA 5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes From the Cell Migration Gateway http cmkb.cellmigration.org report.cgi?report compl overview&compl acc cc00000020 ITGA5 ITGB1 . References reflist External links MeshName Integrin alpha5beta1 http cmkb.cellmigration.org report.cgi?report compl overview&compl acc cc00000020 ITGA5 ITGB1 Info with links in the http www.cellmigration.org index.shtml Cell Migration Gateway membrane protein stub Integrins Category Integrins ... more details
Automatic taxobox authority Karling, 1940 display children 2 Nemertodermatida is a group of bilaterians. ref name pmid19129141 cite journal author Paps J, Bagu J, Riutort M title Lophotrochozoa internal phylogeny new insights from an up to date analysis of nuclear ribosomal genes journal Proc. Biol. Sci. volume 276 issue 1660 pages 1245 54 year 2009 month April pmid 19129141 doi 10.1098 rspb.2008.1574 url http rspb.royalsocietypublishing.org cgi pmidlookup?view long&pmid 19129141 pmc 2660960 ref ref name pmid17051477 cite journal author Jimenez Guri E, Paps J, Garcia Fernandez J, Salo E title Hox and ParaHox genes in Nemertodermatida, a basal bilaterian clade journal Int. J. Dev. Biol. volume 50 issue 8 pages 675 9 year 2006 pmid 17051477 doi 10.1387 ijdb.062167ej url http www.intjdevbiol.com paper.php?doi 10.1387 ijdb.062167ej ref References Wikispecies Nemertodermatida reflist Animalia Category Acoelomorphs invertebrate stub az Nemertodermatida es Nemertodermatida fr Nemertodermatida nl Nemertodermatida pt Nemertodermatida ru Nemertodermatida ... more details
rhombomere has different requirements for Gli proteins. The Hox gene also has been shown to play ... by differential expression of the Hox gene. With mutations in the Hox gene, the cranial motor ... for this was that the Hox gene was somehow involved in regionalization within the neural tube, and that expression ... between closely related neurons from the rhombomeres and Hox gene expression, the Hox gene is still an important factor when it comes to specification of the neuronal phenotype. The Hox gene was expressed ... was regulated by retinoic acid. The Hox gene has been identified in all vertebrates, and the number of Hox genes expressed increases as the vertebrate species diverge farther away from the invertebrate species. Certain neuron groups relate to Hox gene expression. At the r4 level, Hoxb1 is suspected ... references 4. Glover, J.C. Correlated patterns of neuron differentiation and Hox gene expression ... more details
PBB geneid 3217 Homeobox protein Hox B7 is a protein that in humans is encoded by the HOXB7 gene . ref name pmid1973146 cite journal author McAlpine PJ, Shows TB title Nomenclature for human homeobox genes journal Genomics volume 7 issue 3 pages 460 year 1990 month Aug pmid 1973146 pmc doi 10.1016 0888 7543 90 90186 X ref ref name pmid1358459 cite journal author Scott MP title Vertebrate homeobox gene nomenclature journal Cell volume 71 issue 4 pages 551 3 year 1992 month Dec pmid 1358459 pmc doi 10.1016 0092 8674 92 90588 4 ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian ... with a subset of Hox proteins journal Genes Dev. volume 9 issue 6 pages 663 74 publisher location ... cite journal author Peverali FA, D Esposito M, Acampora D, et al. title Expression of HOX homeogenes ... D, Zappavigna V, et al. title Differential expression of human HOX 2 genes along the anterior posterior ... A, et al. title The human HOX gene family. journal Nucleic Acids Res. volume 17 issue 24 pages ... R, et al. title The role of the homeobox gene, HOX B7, in human myelomonocytic differentiation ... with a subset of Hox proteins. journal Genes Dev. volume 9 issue 6 pages 663 74 year 1995 pmid 7729685 ... localisation of three Hox homeoproteins. journal J. Cell. Sci. volume 108 Pt 1 issue pages 187 ... of human HOX gene clusters. journal Cytogenet. Cell Genet. volume 73 issue 1 2 pages 114 5 year ... 1119 97 00411 3 cite journal author Stelnicki EJ, K m ves LG, Kwong AO, et al. title HOX homeobox ... more details
reading citations cite journal author Tabin CJ title Why we have only five fingers per hand hox genes ... pmid 1363084 doi cite journal author Goodman FR title Limb malformations and the human HOX genes. journal ... author Peverali FA, D Esposito M, Acampora D, et al. title Expression of HOX homeogenes in human neuroblastoma ... A, et al. title The human HOX gene family. journal Nucleic Acids Res. volume 17 issue 24 pages 10385 ... by Hox proteins. journal EMBO J. volume 13 issue 14 pages 3339 47 year 1994 pmid 7913891 doi pmc 395231 ... DNA binding partners in trimeric complexes with HOX proteins. journal Mol. Cell. Biol. volume 19 ... title The HOX homeodomain proteins block CBP histone acetyltransferase activity. journal Mol. Cell ... K, Kosaki R, Suzuki T, et al. title Complete mutation analysis panel of the 39 human HOX genes. journal ... more details
PBB geneid 3211 Homeobox protein Hox B1 is a protein that in humans is encoded by the HOXB1 gene . ref name pmid1973146 cite journal author McAlpine PJ, Shows TB title Nomenclature for human homeobox genes journal Genomics volume 7 issue 3 pages 460 year 1990 month Aug pmid 1973146 pmc doi 10.1016 0888 7543 90 90186 X ref ref name pmid1358459 cite journal author Scott MP title Vertebrate homeobox gene nomenclature journal Cell volume 71 issue 4 pages 551 3 year 1992 month Dec pmid 1358459 pmc doi 10.1016 0092 8674 92 90588 4 ref ref name entrez cite web title Entrez Gene HOXB1 homeobox B1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 3211 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes ... Prep1 modulates Pbx Hox protein cooperativity journal EMBO J. volume 17 issue 5 pages 1434 45 publisher ... M, Faiella A, et al. title The human HOX gene family. journal Nucleic Acids Res. volume 17 issue 24 ... by Hox proteins. journal EMBO J. volume 13 issue 14 pages 3339 47 year 1994 pmid 7913891 ... 40155 cite journal author Apiou F, Flagiello D, Cillo C, et al. title Fine mapping of human HOX gene ... homeoprotein Prep1 modulates Pbx Hox protein cooperativity. journal EMBO J. volume 17 issue 5 pages ... of individual Hox genes. journal Development volume 126 issue 12 pages 2751 8 year 1999 pmid 10331985 doi cite journal author Jacobs Y, Schnabel CA, Cleary ML title Trimeric association of Hox and TALE ... R, Suzuki T, et al. title Complete mutation analysis panel of the 39 human HOX genes. journal Teratology ... more details
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