Infobox Disease Name Hereditarymultipleexostoses Image EXT4.jpg Caption Photograph of the legs of a 26 year old male showing multiple lumps leading to deformity. DiseasesDB 33342 ICD10 ICD10 Q 78 6 q ... Hereditarymultipleexostoses HME is a rare medical condition in which multiple bony spurs or lumps ... with Multiplehereditaryexostoses and Multiple osteochondromatosis , which is the preferred ... pmid14349947 cite journal author CANNON JF title Hereditarymultipleexostoses journal American ... ref name pmid3046271 cite journal author McBride WZ title Hereditarymultipleexostoses journal American ... Incomplete penetrance and expressivity skewing in hereditarymultipleexostoses journal Clin. Genet ... in families with hereditarymultipleexostoses journal American Journal of Medical Genetics volume ... JD title Hereditarymultipleexostoses and heparan sulfate polymerization journal Biochimica Biophysica ... cite journal author Stieber JR, Dormans JP title Manifestations of hereditarymultipleexostoses ... iii 1 h HEREDITARYMULTIPLE EXOSTOSES.aspx Medcyclopaedia HereditaryMultiple Exostises http www.geneclinics.org profiles ext GeneReviews HereditaryMultipleExostoses http www.radix.net hogue mhe.htm Information about MultipleHereditaryExostoses MHE http www.hmesg.org.uk HereditaryMultipleExostoses ... type all&labels &details 2 top Images of MultipleHereditaryExostoses MHE from Medical ... cite journal author Schmale GA, Conrad EU, Raskind WH title The natural history of hereditarymultiple ... H, Kinnunen J, Kaitila I, Wolf M, B hling T title Chondrosarcoma in a family with multiplehereditary ... for multipleexostoses to the pericentromeric region of chromosome 11 journal Human Molecular Genetics ... multipleexostoses maps to chromosome 19p journal Human Molecular Genetics volume 3 issue 5 pages 717 ... the knee gallery References reflist 2 External links http MHEResearchFoundation.org HereditaryMultiple ... des exostoses multiples it Esostosi multipla nl Multipele Osteochondromen Hereditaire Multiple Exostosen ... more details
Wiktionary The word multiple can refer to Multiple mathematics , multiples of numbers List of multiple discoveries , instances of scientists, working independently of each other, reaching similar findings Glossary of bets offered by UK bookmakers Multiple bet , types of bet involving two or more selections Parlance for people with multiple identities, sometimes called multiples often theorized as having dissociative identity disorder Multiple birth , because having twins is sometimes called having multiples Multiple Man , a mutant superhero in the Marvel Comics universe Multiple finance , a method used to analyze stock prices Multiples of the P E price to earnings ratio Printmaking where multiple is often used as a term for a print, especially in the US Artist s multiple , series of identical prints, collages or objects by an artist, subverting the idea of the original It is also a singular of multiples , which can refer to Multiples , a 2005 music album by Keith Fullerton Whitman . See also Multiplicity disambiguation disambig fr Multiple ... more details
Infobox Disease Name Hereditary elliptocytosis Image Elliptocytosis.jpg Caption Blood smear showing elliptocytes ... eMedicineSubj ped eMedicineTopic 987 eMedicine mult eMedicine2 med 648 MeshID D004612 Hereditary ... science.19.481.469 issue 481 ref and was first recognised as a heredity hereditary condition in 1932 ... thumb right Hereditary elliptocytosis has an autosomal dominant pattern of inheritance. The incidence of hereditary elliptocytosis is hard to determine, as many sufferers of the milder ... 1962 month July author Bannerman, Rm Renwick, Jh title The hereditary elliptocytoses clinical and linkage ... risk. Because it can confer resistance to malaria , some subtypes of hereditary elliptocytosis are significantly ..., Fd Alpers, Mp Crane, Gg title Hereditary ovalocytosis and reduced susceptibility to malaria in Papua ... text doi 10.1016 0035 9203 87 90001 0 ref Almost all forms of hereditary elliptocytosis are autosomal ... important exception to this rule of autosomal dominance is for a subtype of hereditary elliptocytosis called hereditary pyropoikilocytosis HPP , which is autosomal recessive . There are three major forms of hereditary elliptocytosis common hereditary elliptocytosis, spherocytic elliptocytosis and southeast Asian ovalocytosis. Common hereditary elliptocytosis is the most common form of elliptocytosis ... of clinical expression of hereditary elliptocytosis and pyropoikilocytosis journal Blood journal Blood ... pmidlookup?view long&pmid 3620700 ref Common hereditary elliptocytosis With asymptomatic carrier ... also called hereditary haemolytic ovalocytosis the individual is European descent and elliptocytes and spherocytes are simultaneously present in their blood Pathophysiology Common hereditary elliptocytosis A number of genes have been linked to common hereditary elliptocytosis many involve the same gene as forms of Hereditary spherocytosis , or HS class wikitable Type OMIM Gene EL1 or HS5 ... as a cell is present in a capillary, but in hereditary elliptocytosis the instability of the cytoskeleton ... more details
Multiple issues unreferenced December 2007 context February 2009 notability December 2007 An office, not being held by serjeanty , or attached to some particular office or title, is said to be in gross . Clarify date March 2008 Such offices are inherited in the same manner as a barony by writ by sons in order of birth, and then by daughters. Where there is more than one female heir, the claim is split equally between them or their descendants, disregarding birth order among sisters. Citation needed date December 2009 Examples include the Lord Great Chamberlain the right to carry the spur s at a Coronation of the British monarch coronation vested in the Lord Hastings and the Baron Churston Lord Churston , by descent from the Hastings Earl of Pembroke via Baron Grey of Ruthyn Lord Grey de Ruthyn the Grand Carver of England . Certain Ireland Irish or Scotland Scottish offices, and some others which are doubtful or obsolete, are also held by this form of tenure . DEFAULTSORT Hereditary In Gross Category Titles job stub Ireland law stub UK law stub ... more details
Unreferenced stub auto yes date December 2009 A hereditary witch is one who is born into a tradition of esoteric origin. These traditions are often not recorded, except maybe in grimoire s which are also passed down, but rely primarily on oral and physical tradition. DEFAULTSORT Hereditary Witch Category Witchcraft Occult stub Culture stub ... more details
In set theory , a hereditary set or pure set is a Set mathematics set all of whose elements are hereditary sets. That is, all elements of the set are themselves sets, as are all elements of the elements, and so on. For example, it is vacuously true that the empty set is a hereditary set, and thus the set math varnothing math containing only the empty set math varnothing math is a hereditary set. In formulations of set theory that are intended to be interpreted in the von Neumann universe or to express the content of Zermelo Fraenkel set theory , all sets are hereditary, because the only sort of object that is even a candidate to be an element of a set is another set. Thus the notion of hereditary set is interesting only in a context in which there may be urelement s. The inductive definition of hereditary sets presupposes that set membership is well founded relation well founded i.e., the axiom of regularity , otherwise the recurrence may not have a unique solution. However, it can be restated non inductively as follows a set is hereditary if and only if its transitive set Transitive closure transitive closure contains only sets. In this way the concept of hereditary sets can also be extended to non well founded set theories in which sets can be members of themselves. For example, a set that contains only itself is a hereditary set. See also Hereditarily countable set Well founded set References cite book title Set Theory An Introduction to Independence Proofs author Kunen, Kenneth publisher North Holland year 1980 isbn 0 444 85401 0 Category Set theory settheory stub ... more details
In mathematics , a hereditary property is a property of an object, that inherits to all its subobjects , where the term subobject depends on the context. These properties are particularly considered in topology and graph theory . In topology In topology , a topological property is said to be hereditary if whenever a space has that property, then so does every Subspace topology subspace of it. If the latter is true only for Closed set closed subspaces , then the property is called weakly hereditary . For example, second countability and metrisability are hereditary properties. sequential space Sequentiality and Compact space Hausdorff compactness are weakly hereditary, but not hereditary. ref Goreham, Anthony, http www.citebase.org cgi bin citations?id oai arXiv.org math 0412558 Sequential Convergence in Topological Spaces ref Connected space Connectivity is not weakly hereditary. In graph theory In graph theory , a hereditary property is a graph property property of a graph mathematics graph which also holds for is inherited by its induced subgraph s. ref name AS Cite journal last Alon first Noga author link Noga Alon last2 Shapira first2 Asaf title Every monotone graph property is testable journal SIAM Journal on Computing volume 38 issue 2 year 2008 pages 505 522 doi 10.1137 050633445 url http www.math.tau.ac.il nogaa PDFS monotone1.pdf ref Alternately, a hereditary property is preserved by the removal of vertices. In some cases, the term hereditary has been defined with reference to graph minor s, but this is more properly called a minor hereditary property . The Robertson Seymour theorem implies that a minor hereditary property may be characterized in terms of a finite ... structures of a given signature logic signature is said to have the hereditary propery if every substructure ... s theorem A class K of finitely generated structures has the hereditary property if every ... , every subset of an independent set is again independent. This is also sometimes called the hereditary ... more details
In mathematics , especially in the area of abstract algebra known as module theory , a ring mathematics ring R is called hereditary if all submodule s of projective module s over R are again projective. If this is required only for finitely generated module finitely generated submodules, it is called semihereditary . For a noncommutative ring R , the terms left semi hereditary all finitely generated submodules of projective left R modules are projective and right semi hereditary are sometimes used. A ring can be left hereditary but not right hereditary, and vice versa. In particular, one consequence in fact, an equivalent condition of the left hereditary property is that all left modules have projective resolution s of length at most 1. Hence the usual derived functor s such as math mathrm Ext R i math and math mathrm Tor i R math are trivial for math i 1 math . Examples Semisimple ring s are easily seen to be left and right hereditary This is because all of their left and right ideals are summands of R , and hence are projective. By a similar token, in a von Neumann regular ring every finitely generated left and right ideal is a direct summand of R , and so von Neumann regular rings are left and right semihereditary. For any nonzero element x in a domain R , math R cong xR math via the map math r mapsto xr math . Hence in any domain, a principal right ideal is free, hence projective. This reflects the fact that domains are right Rickart ring s. It follows that if R is a right B zout domain , so that finitely generated right ideals are principal, then R has all finitely generated right ideals projective, and hence R is right semihereditary. Finally if R is assumed to be a principal ideal ring principal right ideal domain , then all right ideals are projective, and R is right hereditary. A commutative hereditary integral domain is called a Dedekind domain . A commutative semi hereditary integral domain is called a Pr fer domain . An important example of a left heredi ... more details
Unreferenced date December 2009 Confusing date March 2008 A hereditary monarchy is the most common type of monarchy and is the form that is used by almost all of the world s existing monarchies. Under a hereditary monarchy, all the monarchs come from the same family, and the The Crown crown is passed down from one member to another member of the family. The hereditary system has the advantages of stability, continuity and predictability, as well as the internal stabilizing factors of family affection and loyalty. For example, when the monarch king or monarch queen of a hereditary monarchy dies or abdicates, the crown is usually passed to the next generation, i.e, his or her child, typically in some order of seniority. When that child dies, the crown is in turn passed to his or her child, or, if no child exists, a sister, brother, niece, nephew, cousin, or other relative. Hereditary monarchies most usually arrange succession by a legislated, definite order of succession so that it is well known beforehand who will be the next monarch. Nowadays, the typical order of succession in hereditary monarchies is based on some form of primogeniture , but there exist other methods such as agnatic seniority seniority , tanistry and rotation , which were much more common in the past. Historically, there have been differences in systems of Order of succession succession , mainly revolving around the question of whether succession is limited only to males, or if females are also eligible to succeed ... regardless of gender. Elective monarchy can practically function as a hereditary monarchy, for example ... even centuries, and that hybrid situation should be described as pseudo elective, virtually hereditary ... officially hereditary in early modern age. See also List of hereditary monarchies Absolute monarchy ... birth DEFAULTSORT Hereditary Monarchy Category Monarchy ar ca Monarquia heredit ria ... ja pl Monarchia dziedziczna pt Monarquia heredit ria ru simple Hereditary ... more details
Peerage No footnotes date December 2008 Hereditary peers form part of the Peerage in the United Kingdom ... of summons . A hereditary title is not necessarily a title of the peerage. For instance, baronet s and baronet ... hereditary title may belong to the peerage, as with life peer s. Peerages may be created by means of letters patent , but the granting of new hereditary peerages has dwindled, with only five having been created since 1965. Origins see History of the peerage The hereditary peerage, as it now exists ... . This order, called a writ , was not originally hereditary, or even a privilege the recipient ... claim of hereditary right to a writ comes from this reign so does the first patent , or charter ... were decided depending on circumstances. Customs changed with time Earldoms were the first to be hereditary ... feudal baronies Scottish feudal barony , in being hereditary, but is long obsolete, the last ... than one hereditary title for example, the same individual may be a duke, an earl, a viscount and a baron ... of a hereditary peerage is determined by the method of its creation. Titles may be created ... with multiple titles to sit in the House of Lords by virtue of one of his father s subsidiary ... generations. A peer may also disclaim a hereditary peerage under the Peerage Act 1963 . To do ..., the peer may not sit or vote in the House of Commons. Prior to the House of Lords Act 1999, a hereditary ... now, however, hereditary peers do not have the automatic right to a writ of summons to the House ... associated with the peerage his wife or her husband is similarly affected. No further hereditary ... it is not hereditary, instead revesting or merging in the Crown if the Prince succeeds to the Crown ... I of England Charles I pictured attempted to withhold a Hereditary peer Writs of summons writ of summons ... to be preferred before the younger of such issue. The number of hereditary peers The number of peers ... Hereditary Peers in 1999 Citation needed date May 2010 Type Male Female Total Prince align right ... more details
Image RGPbadge.jpg 200px thumb right 19th Century Commander s Badge, Russian Grand Priory A Hereditary Commander is a Knight Commander whose family holds that title by hereditary right. Hereditary Commanders .... The award was not hereditary the recipients commanders were obligated to contribute a share of commandery ... hereditary commanderies to 99. ref name Sh337 In 1799 Paul decreed the statute for hereditary commanderies ... ordinary commanderies that provided direct financial benefits to their commanders, hereditary ... roubles annual income. ref name Sh337 Hereditary commanderies remitted 10 of their revenue to the Order ... is that of Grand Master Jean de Lascaris Castellar 1636 1657 granting an hereditary knighthood to the Vicomte ... one Commander per Commandery. Thus only 24 Hereditary Commanders could ever have existed. In Article ... separately. Maltese Tradition There is also an independent tradition of Hereditary knighthood Malta hereditary knighthoods , at a lower rank level, among the gentry of Malta . Changes to the Russian ... to the Commandery were by courtesy allowed, on confirmation from the Russian Emperor, the title Hereditary ... 1844. Qualifications needed by candidates Russian Hereditary Commanders, must be confirmed as such under ... 1955 , page 50. Hereditary Commanders in exile 1928 On June 24, 1928, twelve Russian Hereditary Commanders ... by three other Russian nobles who were aspirants and admitted as Knights, and a Hereditary Commander ... by a Latin cross. Under the guidance of Grand Duke Vladimir, applicants claiming to the Hereditary ... group continued to decline into the 1970s, and lines of several Hereditary Commanders coming ... was acknowledged as a legal part of the Union as well as a number of descendants of the Hereditary ... . The Priory of Dacia has also extended collateral recognition to modern descendants of the Hereditary ... to use the title of Union of Descendants of Hereditary Commanders & etc in 1958, placing the emphasis on descendants of Hereditary Commanders . The group was encouraged to moderate their claims by Grand ... more details
Infobox Disease Name Hereditary hyperbilirubinemia Image Caption DiseasesDB ICD10 ICD10 E 80 4 e 70 ICD10 E 80 6 e 70 ICD9 ICD9 277.4 ICDO OMIM MedlinePlus eMedicineSubj med eMedicineTopic 1065 eMedicine mult eMedicine2 med 1066 MeshID D006933 Hereditary hyperbilirubinemia refers to the condition where levels of bilirubin are elevated, for reasons that can be attributed to a metabolic disorder. An example is Crigler Najjar syndrome . External links http www.som.tulane.edu classware pathology medical pathology New for 99 liver gb sld017.htm cite journal author Elferink RP, Ottenhoff R, Liefting W, de Haan J, Jansen PL title Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia journal J. Clin. Invest. volume 84 issue 2 pages 476 83 year 1989 month August pmid 2760197 doi 10.1172 JCI114189 pmc 548906 Heme metabolism disorders Category Syndromes Category Metabolic disorders Category Inborn errors of metabolism Category Hepatology medicine stub ... more details
about aspects of spherocytosis specific to the hereditary form of the disorder details that apply generally to this variant as well as others Spherocytosis Infobox Disease Name Hereditary spherocytosis Image Caption DiseasesDB 5827 ICD10 ICD10 D 58 0 d 55 ICD9 ICD9 282.0 ICDO OMIM 182900 MedlinePlus eMedicineSubj med eMedicineTopic 2147 MeshID D013103 Hereditary spherocytosis is a genetically transmitted autosomal dominant form of spherocytosis , an auto hemolysis hemolytic anemia characterized by the production of red blood cells that are sphere shaped rather than bi concave disk shaped Donut ... 625 isbn 0 7216 0187 1 oclc doi accessdate ref Symptoms As in spherocytosis non hereditary spherocytosis ... small red blood cell s lacking the central pallor as seen in non hereditary spherocytosis is typically more marked in hereditary spherocytosis. Other protein deficiencies cause hereditary elliptocytosis ... considered part of the diagnostic approach to hereditary spherocytosis. An osmotic fragility ... Hereditary spherocytosis is an autosomal dominant or recessive trait, ref name pmid15071790 cite journal author Eber S, Lux SE title Hereditary spherocytosis defects in proteins that connect ... has a 50 chance of passing the mutation onto his her offspring. Hereditary spherocytosis is caused ... important mutations spectrin and ankyrin variants in hereditary spherocytosis journal Blood Cells ... 4.2 , ref name pmid18940465 cite journal author Perrotta S, Gallagher PG, Mohandas N title Hereditary ... to pass through. In hereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed ... IKutter, D. and Thoma, J. 2006 Hereditary spherocytosis and other hemolytic anomalies distort diabetic ... non hereditary spherocytosis , acute symptoms of anemia and hyperbilirubinemia indicate treatment ... and management of hereditary spherocytosis journal Br. J. Haematol. volume 126 issue 4 pages 455 ... of the spleen. Experimental gene therapy exists to treat hereditary spherocytosis in lab mice however ... more details
Refimprove date June 2007 Infobox Disease Name Hereditary pancreatitis Image Caption DiseasesDB 30026 ICD10 ICD9 ICDO OMIM 167800 MedlinePlus eMedicineSubj eMedicineTopic MeshID Hereditary Pancreatitis is a genetic disease affecting enzyme production in the pancreas. ref cite journal author Whitcomb D title Hereditary pancreatitis new insights into acute and chronic pancreatitis journal Gut volume 45 issue 3 pages 317 22 year 1999 pmid 10446089 url http gut.bmjjournals.com cgi content full 45 3 317 doi 10.1136 gut.45.3.317 pmc 1727629 ref In the pancreas, a genetic mutation causes the enzyme cationin trypsinogen to be made in a way which renders it resistant to inactivation through autolysis . Normally this autolysis mechanism prevents trypsinogen from being activated within the pancreas. However, when the abnormal trypsinogen is activated, it causes a chain reaction where all the trypsinogen in the pancreas is activated, effectively digesting the pancreas from the inside. It can be associated with PRSS1 and SPINK1 . ref OMIM 167800 ref Symptoms and Treatment Symptoms are generally the same as acute pancreatitis , including severe abdominal pain, vomiting, and constipation. There is no treatment for the disease, although complications such as malnutrition can be treated with supplementary pancreatic enzymes. Most estimates place the number of individuals with hereditary pancreatitis in the United States at 1000. Fact date June 2007 References reflist Gastroenterology Congenital malformations and deformations of digestive system Category Medical emergencies Category Gastroenterology pl Dziedziczne zapalenie trzustki pt Pancreatite heredit ria ... more details
Hereditary titles , in a general sense, are title s, positions or Style manner of address style s that are hereditary and thus tend or are bound to remain in particular families. Some hereditary titles are inherited only by the eldest son see primogeniture ref cite web last Murphy first Michael Dean title A Kinship Glossary Symbols, Terms, and Concepts url http www.as.ua.edu ant Faculty murphy 436 kinship.htm accessdate 2006 10 05 ref others may pass to the eldest child of either gender, or to all children of a family equally although this is rare , or can be shared and thus multiplied in the case of a title and or divided in the case of a real object. In some traditions adoption is a common way around biological kinship, as in the Hindu tradition to assure there is a male heir of the same caste . Citation needed date February 2007 Prominent examples of hereditary titles include Hereditary monarchy in the Commonwealth realm s, Bhutan , Brunei , Cambodia , Japan , Thailand , Belgium , Denmark , Luxembourg , Liechtenstein , Monaco , the Netherlands , Norway , Spain , Sweden , Jordan , Morocco , Qatar , Saudi Arabia , Tonga and Bahrain . Different national constitutions use different modes of succession to the inheritance in their monarchies e.g. City of Vatican ex officio the elected pope , and especially in the Orient often adding a choice moment e.g. at a family council to mere birth right which thus only grants only eligibility. A special case are the two elective monarchies, Malaysia ref http www.malaysianmonarchy.org.my portal bi rk1 rk1.htm Yang di Pertuan Agong Bot generated title ref and the United Arab Emirates , where the constituent states of each federation are hereditary ... noble titles e.g. Burgrave, Margrave While the hereditary membership of a privileged class or caste ... External links http www.hereditarytitles.com Hereditary titles http www.aristocracyuk.co.uk hereditary titles a guide Hereditary Titles A Guide http www.heraldica.org topics odegard titlefaq.htm ... more details
Infobox disease Name Hereditary stomatocytosis Image Caption DiseasesDB 29710 ICD10 ICD10 D 58 8 d 55 ICD9 ICD9 282.8 ICDO OMIM 185000 OMIM mult OMIM2 185010 MedlinePlus eMedicineSubj eMedicineTopic Hereditary stomatocytosis describes a number of inherited autosomal dominant human conditions which affect the red blood cell, in which the membrane or outer coating of the cell leaks sodium and potassium ions. Pathophysiology Osmosis leads to the red blood cell having a constant tendency to swell and burst. This tendency is countered by manipulating the flow of sodium and potassium ions. A pump forces sodium out of the cell and potassium in, and this action is balanced by a process called the passive leak . In the hereditary stomatocytoses, the passive leak is increased and the cell becomes swamped with salt and water. The cell lyses and a haemolytic anaemia results. For as yet unknown reasons, the cells take on an abnormal shape, resembling a mouth or stoma . Variants Haematologists have identified a number of variants. These can be classified as below. Overhydrated hereditary stomatocytosis Dehydrated HSt hereditary xerocytosis hereditary hyperphosphatidylcholine haemolytic anaemia Dehydrated with perinatal ascites Cryohydrocytosis Blackburn variant. Familial pseudohyperkalaemia There are other families that do not fall neatly into any of these classifications. ref cite journal author Oski FA, Naiman JL, Blum SF, et al. title Congenital hemolytic anemia with high sodium, low potassium red cells. Studies of three generations of a family with a new variant journal N. Engl. J. Med. volume 280 issue 17 pages 909 16 year 1969 pmid 4237839 doi 10.1056 NEJM196904242801701 url ref Stomatocytosis is also found as a hereditary disease in Alaskan malamute and miniature schnauzer dogs ... occur for which anticoagulation may be needed. Causes The cause for these hereditary conditions is now ..., Iarocci TA, et al. title Hereditary stomatocytosis consistent association with an integral membrane ... more details
Globalize date December 2010 Infobox disease Name Hereditary angioedema Image Caption DiseasesDB 1821 ICD10 D84.1 ILDS D84.110 ICD9 277.6 OMIM 106100 MedlinePlus 001456 eMedicineSubj article eMedicineTopic 1048994 MeshID D054179 Hereditary angioedema types I and II also known as Quincke edema after discoverer Heinrich Quincke presents in the second to fourth decade, and is characterized by local swelling in subcutaneous tissues. ref name Andrews James, William Berger, Timothy Elston, Dirk 2005 . Andrews Diseases of the Skin Clinical Dermatology . 10th ed. . Saunders. ISBN 0 7216 2921 0. ref rp 152 Hereditary angioma is caused by a deficiency of the C1 inhibitor, a protein of the complement system , a part of the immune system. Some mutations produce low levels of C1 inhibitor type I others produce normal levels of ineffective C1 protein type II . ref name Morgan http www.nejm.org doi full 10.1056 NEJMe1006450 Hereditary Angioedema Therapies Old and New , B. Paul Morgan, M.B., Ph.D., N Engl J Med 2010 363 581 583August 5, 2010 PubMed citation not yet available ref C1 inhibitor is needed to control the coagulation cascade in blood clotting, the complement cascade in the immune system ... Deficiency of C1 inhibitor causes hereditary angioedema types I and II. This autosomal dominant disorder ..., thus when these go unregulated they can give rise to vasoactive substances. Hereditary angioedema ... rates from hereditary angioma are high in the U.S. but rare in Europe. Older and newer preparations ... in Europe but not by the F.D.A. . ref name Morgan In hereditary angioedema, specific stimuli that have ... author Gelfand JA, Sherins RJ, Alling DW, Frank MM title Treatment of hereditary angioedema with danazol ... kallikrein inhibitor for the treatment of hereditary angioedema and the prevention of blood loss ... cite journal author Bernstein JA title Hereditary angioedema a current state of the art review ... Hereditary Angioedema Category Urticaria and angioedema Category Disorders of globin and globulin ... more details
Infobox disease Name Hereditary coproporphyria Image Coproporphyrinogen III.svg Caption Coproporphyrinogen III DiseasesDB 30591 ICD10 ICD10 E 80 2 e 70 ILDS E80.222 ICD9 ICD9 277.1 ICDO OMIM 121300 MedlinePlus eMedicineSubj med eMedicineTopic 1888 MeshID D046349 Hereditary coproporphyria HCP is a form of Hepatic porphyrias hepatic porphyria associated with a deficiency of the enzyme coproporphyrinogen III oxidase . ref name pmid16159891 cite journal title Mutations in human CPO gene predict clinical expression of either hepatic hereditary coproporphyria or erythropoietic harderoporphyria journal Hum. Mol. Genet. volume 14 issue 20 pages 3089 98 year 2005 month October pmid 16159891 doi 10.1093 hmg ddi342 url http hmg.oxfordjournals.org cgi pmidlookup?view long&pmid 16159891 display authors 3 author1 Schmitt C author2 Gouya L author3 Malonova E author separator , last4 Lamoril first4 J last5 Camadro first5 JM last6 Flamme first6 M last7 Rose first7 C last8 Lyoumi first8 S last9 Da Silva first9 V ref ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref rp 525 Hereditary coproporphyria HCP is an autosomal dominant ref name pmid12181641 cite journal title Two novel mutations and coexistence of the 991C T and the 1339C T mutation on a single allele in the coproporphyrinogen oxidase gene in Swedish patients with hereditary ... Pathophysiology Hereditary coproporphyria is the result of a point mutation in the coproporphinogen oxidase CPO gene. ref name OMIM ref name pmid16176984 cite journal title Structural basis of hereditary ... title Systematic analysis of coproporphyrinogen oxidase gene defects in hereditary coproporphyria ... ch160 ch160c.html Retrieved 5 February 2011. ref Cases noted hereditary coproporphyria induced ... Hereditary Coproporphyria Category Inborn errors of metabolism Category Porphyrias Category Skin conditions ... more details
Hereditary pyropoikilocytosis HPP is an autosomal recessive form of hemolytic anemia characterized by an abnormal sensitivity of red blood cell s to heat and erythrocyte morphology similar to that seen in thermal burns. Patients with HPP tend to experience severe haemolysis and anaemia in infancy that gradually improves, evolving toward typical elliptocytosis later in life. However, the hemolysis can lead to rapid sequestration and destruction of red cells. Splenectomy is curative when this occurs. HPP has been associated with a defect of the erythrocyte membrane protein spectrin and with spectrin deficiency . See also Erythrocyte Hereditary elliptocytosis Poikilocytosis List of hematologic conditions References cite journal author Zarkowsky HS, Mohandas N, Speaker CB, Shohet SB title A congenital haemolytic anaemia with thermal sensitivity of the erythrocyte membrane journal Br J Haematol year 1975 pages 537 43 volume 29 issue 4 pmid 1191563 doi 10.1111 j.1365 2141.1975.tb02740.x cite journal author Gallagher PG title Red cell membrane disorders journal Hematology Am Soc Hematol Educ Program year 2005 pages 13 8 volume 2005 pmid 16304353 doi 10.1182 asheducation 2005.1.13 http www.asheducationbook.org cgi content full 2005 1 13 Full text cite journal author Cameron, John L journal Current Surgical Therapy 9th edition page 547 year 2008 Category Blood disorders Category Autosomal recessive disorders disease stub ... more details
disability Multiple disabilities designs a person with several disabilities, such as a Disability Sensory disability sensory disability associated with a motor disability . Depending on the definition, a severe intellectual disability may be included in the term multiple disabilities . References http education.stateuniversity.com pages 2415 Severe Multiple Disabilities Education individuals With.html Severe and Education of individuals With Multiple Disabilities Definition and Types of Severe and Multiple Disabilities , MARTHA E. SNELL, StateUniversity.com http www.angelswithspecialneeds.org monthly severe and multiple disabilities Severe and Multiple Disabilities , September 2, 2007, www.angelswithspecialneeds.org http www.nichcy.org Disabilities Specific Pages severe multiple.aspx Severe and or Multiple Disabilities , NICHCY National Dissemination Center for People with Disabililites Category Disability Disability stub fr Plurihandicap fr Polyhandicap ... more details
Infobox Disease Name Multiple sclerosis Image MS Demyelinisation CD68 10xv2.jpg Caption Demyelinization ... pmr 82 eMedicine2 radio 461 MeshID D009103 Multiple sclerosis abbreviated MS, also known as disseminated .... ref name pmid18970977 cite journal author Compston A, Coles A title Multiple sclerosis journal ... cite journal author Rosati G title The prevalence of multiple sclerosis in the world an update ... signals. ref name pmid11955556 The name multiple sclerosis refers to scars scleroses&mdash better ..., especially as the disease advances. ref name pmid8780061 There is no known cure for multiple sclerosis ... Multiple Sclerosis Society standardized four subtype definitions ref name pmid8780061 relapsing remitting ... , ref name pmid18219812 cite journal author Pittock SJ, Rodriguez M title Benign multiple sclerosis ... suggestive of demyelination , but does not fulfill the criteria for multiple sclerosis. ref name pmid18970977 ... M title Clinically isolated syndromes suggestive of multiple sclerosis, part I natural history ... M title Secondary progressive multiple sclerosis current knowledge and future challenges journal ... Miller DH, Leary SM title Primary progressive multiple sclerosis journal Lancet Neurol volume 6 issue ... myelinoclastic sclerosis Schilder s diffuse sclerosis and Marburg multiple sclerosis . There is debate ... Stadelmann C, Br ck W title Lessons from the neuropathology of atypical forms of multiple sclerosis ... 15727225 doi url ref Multiple sclerosis also behaves differently in children, taking more time to reach ... than adults. ref name pmid18970977 Signs and symptoms Main Multiple sclerosis signs and symptoms File Symptoms of multiple sclerosis.png thumb right Main symptoms of multiple sclerosis A person with MS ... in multiple sclerosis an expanded disability status scale EDSS journal Neurology volume 33 issue 11 ... author Fred D. Lublin Lublin FD , Reingold SC title Defining the clinical course of multiple sclerosis results of an international survey. National Multiple Sclerosis Society USA Advisory Committee ... more details
Unreferenced stub auto yes date December 2009 Orphan date December 2009 Multiple trapeze is an act entailing the use of more than one trapeze , typically two or three. In these acts, multiple people perform simultaneously. The most common type of multiple trapeze is a triple trapeze . A triple trapeze has one long bar, held up by a ropes, basically three trapeze s put together, with the middle trapeze sharing the ropes of the other two. Multiple trapeze can also refer to an abstract structure with trapeze like structures, inside which multiple artists may perform. An experimental cage like structure was created by Cirque du Soleil for their show Varekai which was ultimately scrapped in production. However, the structure did appear in the Making of documentary, Fire Within. DEFAULTSORT Multiple Trapeze Category Circus skills Theat stub ... more details
Unreliable sources date September 2009 In mathematics , a multiple is the Multiplication product of any quantity and an integer . ref MathWorld urlname Multiple title Multiple ref ref http wordnetweb.princeton.edu perl webwn?s multiple WordNet lexicon database, Princeton University ref ref http www.wordreference.com definition multiple WordReference.com ref In other words, for the quantities a and b , we say that b is a multiple of a if b na for some integer n , which is called the multiplier or coefficient . If a is not zero , this is equivalent to saying that b a is an integer with no remainder . ref http www.thefreedictionary.com multiple The Free Dictionary by Farlex ref ref http dictionary.reference.com browse multiple Dictionary.com Unabridged ref ref http dictionary.cambridge.org define.asp?key 52498&dict CALD Cambridge Dictionary Online ref If a and b are both integers, and b is a multiple of a , then a is called a divisor of b . kb The product of two integers is sometimes called an integer multiple . ref http mdk12.org instruction curriculum mathematics glossary.shtml Mathematics Glossary Voluntary Stat Curriculum ref Examples 14, 49, 0 and 21 are multiples of 7 whereas 3 and 6 are not. This is because there are integers that 7 may be multiplied by to reach the values of 14, 49, 0 and 21, while there are no such integers for 3 and 6. Each of the products listed below, and in particular, the products for 3 and 6, is the only way that the relevant number can be written ... 0 is a multiple of everything math 0 0 cdot b math . The product of any integer math n math and any integer is a multiple of math n math . In particular, math n math , which is equal to math n times 1 math , is a multiple of math n math every integer is a multiple of itself , since 1 is an integer ... prefix DEFAULTSORT Multiple Mathematics Category Arithmetic Category Multiplication an Multiplo bg de Vielfaches es M ltiplo fr Multiple math matiques it Multiplo ko nl Veelvoud wiskunde ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD10 Q 87 q 80 ICD9 ICD9 759.7 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D000015 Multiple abnormalities multiple anomaly , multiple deformity is a term used to describe congenital abnormality that can not be primarily identified with a single system of the body or single disease process. Although most medical conditions can have systemic sequela e, the term is generally reserved where the effects on multiple systems is immediately obvious. medicine stub Phakomatoses and other congenital malformations not elsewhere classified ... more details
Image Mulberry china.JPG thumb Mulberry is a kind of multiple fruit. Multiple fruits are fruits that are formed from a cluster of flowers called an inflorescence . Each flower in the inflorescence produces a fruit, but these mature into a single mass. ref cite book last Schlegel title Encyclopedic Dictionary url http books.google.com books?vid ISBN1560229500&id 7J 3fD67RqwC&pg PA282&lpg PA282&vq Multiple fruit&dq acarpous&sig mnPOH HP 2Ow6lX916y7uf 9Zzo page 282 ref Examples are the pineapple , ficus fig , mulberry , osage orange , and breadfruit . Image Noni fruit dev.jpg thumb 200px left In some plants, such as this noni , flowers are produced regularly along the stem and it is possible to see together examples of flowering, fruit development, and fruit ripening In the photograph on the left, stages of flowering and fruit development in the noni or Indian mulberry Morinda citrifolia can be observed on a single branch. First an inflorescence of white flowers called a head is produced. After Fertilization Fertilisation in plants fertilization , each flower develops into a drupe, and as the drupes expand, they become connate merge into a multiple fleshy fruit called a syncarpet . There are also many dry multiple fruits. Other examples of multiple fruits Platanus , teasel , Asteraceae multiple achenes from multiple flowers, in a single fruit structure Morus plant Mulberry , multiple flowers form one fruit Common Fig , multiple flowers form one fruit inside the fruit Similar structures are formed from single flowers that have more than one pistil , and these are called aggregate fruits , e.g. Strawberry , aggregate of achenes on a fleshy Receptacle botany receptacle Tuliptree , aggregate of samaras. Sweet gum , aggregate of capsules. Magnolia , aggregate of follicles. See also Fruits Compound fruit References reflist fruits Category Fruit Category Compound fruit Category Plant morphology ar cs Plodenstv hi sr zh ... more details
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