charged gangliosides in animals. The head group of a glycolipid is composed of sugars ... Reflist External links MeshName Glycolipids Sphingolipids Glycolipid metabolism Category Carbohydrate ... more details
Pfam box Symbol GLTP Name Glycolipid transfer protein GLTP image PDB 1swx EBI.jpg width caption Pfam PF08718 InterPro IPR014830 SMART Prosite SCOP TCDB OPM family 92 OPM protein 1swx PDB PDB3 1swx A 6 207 PDB3 2evt A 6 207 PDB3 1sx6 A 6 207 PDB3 1wbe A 6 207 PDB3 2bv7 A 6 207 PDB3 1tfj A 6 207 Glycolipid transfer protein is a cytosolic protein that catalyses the transfer of glycolipid s between different intracellular membranes. ref name PUB00035403 cite journal author Brown RE, Lin X, Rao CS, Pike HM, Molotkovsky JG title Glycolipid transfer protein mediated transfer of glycosphingol ipids between membranes a model for action based on kinetic and thermodynamic analyses journal Biochemistry volume 43 issue 43 pages year 2004 pmid 15504043 doi 10.1021 bi0492197 pmc 2596630 ref ref name PUB00035404 cite journal author Nymalm Y, Airenne TT, Kidron H, Salminen TA, Nylund M, West G, Mattjus P title Structural evidence for adaptive ligand binding of glycolipid transfer protein journal J. Mol. Biol. volume 355 issue 2 pages year 2006 pmid 16309699 doi 10.1016 j.jmb.2005.10.031 ref This protein transport primarily different glycosphingolipid s and glyceroglycolipid s between intracellular membranes, but not phospholipid s. It might be also involved in translocation of glucosylceramide s. It was found in brain, kidney, spleen, lung, cerebellum, liver and heart. Human proteins containing this domain GLTP PLEKHA8 PLEKHA9 References reflist External links http www.ebi.uniprot.org entry P68265 Uniprot entry http www.sanger.ac.uk cgi bin Pfam getacc?PF08718 Pfam entry UMichOPM families superfamily 92 Calculated spatial position of Glycolipid transfer protein in membrane Category Peripheral membrane proteins Category Water soluble transporters Category Protein domains membrane protein stub ... more details
enzyme Name glycolipid 2 alpha mannosyltransferase EC number 2.4.1.131 CAS number 74506 43 7 IUBMB EC number 2 4 1 131 GO code 0004377 image width caption In enzymology , a glycolipid 2 alpha mannosyltransferase EC number 2.4.1.131 is an enzyme that catalysis catalyzes the chemical reaction in which an alpha D mannose mannosyl residue is transferred from GDP mannose to lipid linked oligosaccharide , being attached by an alpha 1,2 D mannosyl D mannose bond. This enzyme belongs to the family of glycosyltransferase s, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP mannose glycolipid 1,2 alpha D mannosyltransferase . Other names in common use include guanosine diphosphomannose oligosaccharide lipid , mannosyltransferase , GDP mannose oligosaccharide lipid mannosyltransferase , and oligosaccharide lipid mannosyltransferase . Structural studies As of late 2007, 3 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1S4N , PDB link 1S4O , and PDB link 1S4P . References reflist 1 cite journal author Schutzbach JS, Springfield JD, Jensen JW date 1980 title The biosynthesis of oligosaccharide lipids. Formation of an alpha 1,2 mannosyl mannose linkage journal J. Biol. Chem. volume 255 pages 4170&ndash 5 pmid 6154707 issue 9 enzyme stub Category EC 2.4.1 Category Enzymes of known structure ... more details
enzyme Name glycolipid 3 alpha mannosyltransferase EC number 2.4.1.132 CAS number 81181 76 2 IUBMB EC number 2 4 1 132 GO code 0004378 image width caption In enzymology , a glycolipid 3 alpha mannosyltransferase EC number 2.4.1.132 is an enzyme that catalysis catalyzes the chemical reaction in which an alpha D mannose mannosyl residue is transferred from GDP mannose to a lipid linked oligosaccharide , being attached by an alpha 1,3 D mannosyl D mannose bond. This enzyme belongs to the family of glycosyltransferase s, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP mannose glycolipid 1,3 alpha D mannosyltransferase . Other names in common use include mannosyltransferase II , guanosine diphosphomannose oligosaccharide lipid II , mannosyltransferase , and GDP mannose oligosaccharide lipid mannosyltransferase II . This enzyme participates in the biosynthesis of n glycan and glycan structures. References reflist 1 cite journal author Jensen JW, Schutzbach JS date 1981 title The biosynthesis of oligosaccharide lipids. Partial purification and characterization of mannosyltransferase II journal J. Biol. Chem. volume 256 pages 12899&ndash 904 pmid 7309740 issue 24 enzyme stub Category EC 2.4.1 Category Enzymes of unknown structure ... more details
enzyme Name dolichyl phosphate mannose glycolipid alpha mannosyltransferase EC number 2.4.1.130 CAS number 77967 76 1 IUBMB EC number 2 4 1 130 GO code 0004584 image width caption In enzymology , a dolichyl phosphate mannose glycolipid alpha mannosyltransferase EC number 2.4.1.130 is an enzyme that catalysis catalyzes the chemical reaction in which an alpha D mannose mannosyl residue is transferred from a dolichyl phosphate D mannose molecule into a plasma membrane membrane lipid linked oligosaccharide . This enzyme belongs to the family of glycosyltransferase s, specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl phosphate D mannose glycolipid alpha D mannosyltransferase . Other names in common use include dolichol phosphomannose oligosaccharide lipid mannosyltransferase , and oligomannosylsynthase . This enzyme participates in n glycan biosynthesis and glycan structures biosynthesis 1 . References reflist 1 cite journal author Rearick JI, Fujimoto K, Kornfeld S date 1981 title Identification of the mannosyl donors involved in the synthesis of lipid linked oligosaccharides journal J. Biol. Chem. volume 256 pages 3762&ndash 9 pmid 6163773 issue 8 enzyme stub Category EC 2.4.1 Category Enzymes of unknown structure ... more details
Unreferenced date February 2008 A saponifiable lipid is one with an ester functional group, that can be hydrolysis hydrolyzed under basic conditions. These include triglyceride s, phospholipids , glycolipid s, sphingolipid s, and the wax es. These lipids are known as simple lipids . See also Lipids Category Lipids biochem stub ... more details
Ceramide glucosyltransferase or glucosylceramide synthase is a glucosyltransferase enzyme involved in the production of glucosylceramide . It is classified under EC number 2.4.1.80 . It is inhibited by miglustat . See also Glucosylceramide External links MeshName Ceramide glucosyltransferase Glycosyltransferases Glycolipid sphingolipid metabolism enzymes Category Transferases transferase stub it Ceramide glucosiltransferasi ... more details
PBB geneid 51228 Glycolipid transfer protein is a protein that in humans is encoded by the GLTP gene . ref name pmid15287756 cite journal author Li XM, Malakhova ML, Lin X, Pike HM, Chung T, Molotkovsky JG, Brown RE title Human glycolipid transfer protein probing conformation using fluorescence spectroscopy journal Biochemistry volume 43 issue 31 pages 10285 94 year 2004 month Aug pmid 15287756 pmc 2593833 doi 10.1021 bi0495432 ref ref name pmid15901739 cite journal author Malakhova ML, Malinina L, Pike HM, Kanack AT, Patel DJ, Brown RE title Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex journal J Biol Chem volume 280 issue 28 pages 26312 20 year 2005 month Jul pmid 15901739 pmc 1393170 doi 10.1074 jbc.M500481200 ref ref name entrez cite web title Entrez Gene GLTP glycolipid transfer protein url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 51228 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein. ref name entrez cite web title Entrez Gene GLTP glycolipid ... cite journal author Brown RE, Mattjus P title Glycolipid transfer proteins. journal Biochim. Biophys ... 1986823 cite journal author Abe A title Primary structure of glycolipid transfer protein from pig ... of glycolipid transfer protein from bovine and porcine brain. journal J. Biol. Chem. volume 275 issue ... pmc 528928 cite journal author Rao CS, Lin X, Pike HM, et al. title Glycolipid transfer protein mediated ... 10.1021 bi0492197 pmc 2596630 cite journal author Rao CS, Chung T, Pike HM, Brown RE title Glycolipid ... of glycolipid transfer protein is controlled by glycolipid acyl structure. journal PLoS Biol. volume ... more details
Lipid metabolism refers to the processes that involve the creation and degradation of lipid s. The types of lipids involved include Bile salt s Cholesterol s Eicosanoid s Glycolipid s Ketone bodies Fatty acids see also fatty acid metabolism Phospholipid s Sphingolipid s Steroid see also steroidogenesis Triacylglycerol s fats see also lipolysis and lipogenesis External links MeshName Lipid metabolism Ophardt, Charles E. 2003 http www.elmhurst.edu chm vchembook 622overview.html Lipid Catabolism Summary . Virtual Chembook. Elmhurst College. King, Michael W. http themedicalbiochemistrypage.org lipid synthesis.html Fatty Acid, Omega 3 and Omega 6 Fatty Acid, Triglyceride, and Phospholipid Synthesis and Metabolism . The Medical Biochemistry Page. Metabolism Lipid metabolism enzymes Eicosanoid metabolism enzymes Glycolipid sphingolipid metabolism enzymes Ketone and cholesterol metabolism enzymes Category Lipids Category Metabolism biochemistry stub ... more details
Orphan date February 2009 Cording , in mycobacteriology, refers to a tendency of some mycobacterium especially M. tuberculosis to grow end to end, giving them a rope or cord like appearance when viewed on a stained slide through a microscope. This growth pattern is due to cord factor , a glycolipid , and contributes to the virulence of the organism. References 1. Diagnostic Bacteriology A Study Guide, Margaret A. Bartelt, 2000, F.A. Davis Company. Category Bacteriology biology stub ... more details
Unreferenced date December 2009 A slime layer in bacteria is an easily removed, diffuse, unorganized layer of extracellular material that surrounds bacteria cells. Specifically, this consists mostly of exopolysaccharide s, glycoprotein s, and glycolipid s. The slime layer is not to be confused with the S layer , a separate and highly organised glycoprotein layer surrounding many bacterial cells. The function of the slime layer is to protect the bacteria cells from environmental dangers such as antibiotic s and desiccation . The slime layer also allows bacteria to adhere to smooth surfaces such as prosthetic medical devices and catheter s. It may permit bacterial colonies to survive chemical sterilization microbiology sterilization with chlorine , iodine , and other chemicals, leaving autoclaving or flushing with boiling water as the only certain methods of decontamination . A bacterial capsule microbiology capsule is similar, but is a well ordered structure that is resistant to washing off. Bacteria DEFAULTSORT Slime Layer Category Bacteriology Category Microbiology cs Slizov vrstva ... more details
Orphan date February 2009 PBB geneid 26301 Globoside alpha 1,3 N acetylgalactosaminyltransferase 1 is an enzyme that in humans is encoded by the GBGT1 gene . ref name pmid10506200 cite journal author Xu H, Storch T, Yu M, Elliott SP, Haslam DB title Characterization of the human Forssman synthetase gene. An evolving association between glycolipid synthesis and host microbial interactions journal J Biol Chem volume 274 issue 41 pages 29390 8 year 1999 month Nov pmid 10506200 pmc doi 10.1074 jbc.274.41.29390 ref ref name pmid8855242 cite journal author Haslam DB, Baenziger JU title Expression cloning of Forssman glycolipid synthetase a novel member of the histo blood group ABO gene family journal Proc Natl Acad Sci U S A volume 93 issue 20 pages 10697 702 year 1996 month Nov pmid 8855242 pmc 38217 doi 10.1073 pnas.93.20.10697 ref ref name entrez cite web title Entrez Gene GBGT1 globoside alpha 1,3 N acetylgalactosaminyltransferase 1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 26301 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text This gene encodes a member of the histo blood group ABO gene family that encodes glycosyltransferases with related but distinct substrate specificity. This protein plays a role in synthesizing Forssman glycolipid FG , a member of the globoseries glycolipid family. Human cells do not normally produce FG but produce the precursor glycolipids globotriaosylceramide and globoside. This protein may be involved in the tropism and binding of pathogenic organisms. ref name entrez cite web title Entrez Gene GBGT1 globoside alpha 1,3 N acetylgalactosaminyltransferase 1 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 26301 accessdate ref References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Gerhard DS, Wagner L, Feingold ... more details
Cord factor refers to lipoarabinomannan, a molecule generated from trehalose dimycolate by virulent strains of Mycobacterium tuberculosis and closely related species. ref MeshName Cord factor ref ref name pmid18524936 cite journal author Welsh KJ, Abbott AN, Hwang SA, et al. title A role for tumour necrosis factor alpha, complement C5 and interleukin 6 in the initiation and development of the mycobacterial cord factor trehalose 6,6 dimycolate induced granulomatous response journal Microbiology Reading, Engl. volume 154 issue Pt 6 pages 1813 24 year 2008 month June pmid 18524936 doi 10.1099 mic.0.2008 016923 0 url http mic.sgmjournals.org cgi pmidlookup?view long&pmid 18524936 pmc 2556040 ref It is a surface glycolipid which blocks macrophage activation by IFN , induces secretion of TNF and causes Mycobacterium tuberculosis to form cords in vitro . See also Nocardia Cording mycobacterium References reflist Toxins Category Bacteriology biology stub ... more details
Infobox disease Name Sphingolipidoses Image Caption DiseasesDB 33438 ICD10 ICD10 E 75 3 e 70 ICD9 ICD9 272.7 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D013106 Sphingolipidoses are a class of disorders relating to Sphingolipid metabolism. Accumulated products Gangliosides Gangliosidosis GM1 gangliosidoses GM2 gangliosidoses Tay Sachs disease Sandhoff disease Glycolipid s Fabry s disease Krabbe disease Metachromatic leukodystrophy Glucocerebroside s Gaucher s disease Overview class wikitable Comparison of the main sphingolipidoses ref name brschemi If not otherwise specified, reference is cite book author Marks, Dawn B. Swanson, Todd Sandra I Kim Marc Glucksman title Biochemistry and molecular biology publisher Wolters Kluwer Health Lippincott Williams & Wilkins location Philadelphia year 2007 pages isbn 0 7817 8624 X oclc doi accessdate ref Disease Deficient enzyme Accumulated products Symptoms Inheritance Niemann Pick disease Sphingomyelinase Sphingomyelin in brain and red blood cell RBC s Mental retardation Spasticity Seizures Ataxia Death by 2 3 years Autosomal recessive Fabry disease galactosidase A Glycolipid s in brain, heart, kidney Ischemic infarction in affected organs Acroparesthesia Angiokeratoma s hypohidrosis X linked ref name urlFabry Disease eMedicine Pediatrics Genetics and Metabolic Disease cite web url http emedicine.medscape.com article 951451 overview title Fabry Disease author Banikazemi M, Desnick RJ, Astrin KH authorlink coauthors date 2009 07 08 format work eMedicine Pediatrics Genetics and Metabolic Disease publisher Medscape pages language archiveurl archivedate quote accessdate 2010 12 31 ref Krabbe disease Galactocerebrosidase Glycolipids in oligodendrocytes Spasticity Neurodenegeration leading to death Hypertonia Hyperreflexia Decerebration like posture Blindness Deafness Autosomal recessive Gaucher disease Glucocerebrosidase Glucocerebroside s in RBCs, liver and spleen Hepatosplenomegaly Anemia Thrombocytopenia Bone pai ... more details
wiktionarypar lam TOCright Lam and its various forms may refer to l m lamedh , a letter of the Arabic alphabet Lam Mor lam , an ancient Lao form of song in Laos and Isan Lam saravane , a music genre Lam luang , a music genre Lam, Germany , a town in Bavaria LAM Lactational amenorrhea method , a contraceptive method LAM Mozambique Airlines , the National airline of Mozambique LAM, an internet slang acronym meaning leave a message LAM, the International Air Transport Association airport code for Los Alamos Airport LAM MPI , an MPI programming environment and development system for heterogeneous computers on a network or Local Area Multicomputer London After Midnight band , an L.A. Band. Lymphangioleiomyomatosis , a rare lung disease The collection code of the Natural History Museum of Los Angeles County Lipoarabinomannan , a glycolipid associated with the cell wall of Mycobacterium tubercolosis Laser aiming module , a term for laser sights for firearms Laser capture microdissection , also known as Laser Assisted Microdissection Lam. May be an abbreviation for The Book of Lamentations in the Tanakh Jean Baptiste Lamarck 1744&ndash 1829 , French naturalist Lamborghini Surname Lam, a surname in Southern India. Lam, a common Yue Chinese Cantonese Chinese surname and to a lesser extent, Vietnamese. It is a variant of the Mandarin Chinese Lin surname Lam, a common Hakka Chinese surname. It is a variant of the Mandarin Chinese Lan surname which literally means blue . It is sometimes written as Lum . See also Tai Lam Country Park , Hong Kong Po Lam , area of Hong Kong Lam Research , semiconductor design company Phra Lak Phra Lam , Lao version of the Ramayana Monts de Lam , a department of Chad Lum Invader , a fictional character from the manga and anime series Urusei Yatsura whose name is sometimes romanized as Lam disambig Category Surnames de LAM eo LAM fr Lam it LAM nl Lam ja LAM no Lam pl LAM pt Lam vi Lam ... more details
GPI may refer to Alpha GPI , a Brazilian submachine gun. cole internationale primaire de Greenfield Park Greenfield Park International , a primary school in Greenfield Park, Quebec Greenfield Park , Quebec , Canada . Gas Petroleum&Properties Investments, LLC. Limited Liability Company, Oil Trading and Investment Consulting, Premium Real Estate Brokers based in Dubai, United Arab Emirates. Gemini Planet Imager , an instrument being built to directly image extrasolar planet s Gender Parity Index , a measure that reflects females level of access to education compared to that of males access. General paresis of the insane , a now rare neuropsychiatric disorder affecting the brain and central nervous system General Purpose Interface , Standard contact closure format used in broadcast level post production equipment, allowing computer based editing equipment to synchronously start at the same time. GPIO General Purpose Input Genuine Progress Indicator , a concept economics that has been suggested as a replacement metric for gross domestic product Glacier Park International Airport , a public airport serving Flathead County, Montana Glass Packaging Institute , a trade association for the U.S. glass container industry Global Partnership Initiative , an initiative of the United Nations Human Settlement Programme UN HABITAT . Global Peace Index , an index for the relative position of nations and regions peacefulness Global Poverty Initiative , a student group at Massachusetts Institute of Technology focused on alleviating worldwide poverty that hosted the Inaugural Millennium Campus Network Conference in April 2008. Global Protection & Intelligence, Inc. Private Public Figure, Executive, Diplomatic protective service based in Los Angeles, California USA. Internal globus pallidus , a part of the basal ganglia . Glucose 6 phosphate isomerase Glucose Phosphate Isomerase , an enzyme Glycophosphatidylinositol , a glycolipid that can be attached to the C terminus of a protein duri ... more details
chembox ImageFile Lyxose.png ImageSize 180px ImageFile1 Alpha D Lyxopyranose.svg ImageSize1 150px IUPACName 2R,3R,4S 2,3,4,5 Tetrahydroxypentanal OtherNames L Lyxose br Lyxopyranose Section1 Chembox Identifiers CASNo 1949 78 6 PubChem 65550 SMILES C C H C H C H C O O O O O Section2 Chembox Properties Formula C sub 5 sub H sub 10 sub O sub 5 sub MolarMass 150.13 Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Lyxose is an aldopentose &mdash a monosaccharide containing five carbon atom s, and including an aldehyde functional group . It has chemical formula carbon sub 5 sub hydrogen sub 10 sub oxygen sub 5 sub . Lyxose occurs only rarely in nature for example, as a component of bacterial glycolipid s. ref name ACS Kay Hooi Khoo et al. , Chemistry of the Lyxose Containing Mycobacteriophage Receptors of Mycobacterium phlei Mycobacterium smegmatis, Biochemistry , 35 36 , 11812 11819, 1996. http pubs.acs.org cgi bin abstract.cgi bichaw 1996 35 i36 abs bi961055 .html Abstract ref See also Arabinose Deoxyribose Ribose Ribulose Xylose Xylulose References Reflist External links http biocyc.org ECOLI NEW IMAGE?type PATHWAY&object LYXMET PWY E. coli K 12 Pathway L lyxose degradation Carbohydrates Category Aldopentoses de Lyxose es Lixosa fr Lyxose fy Lyksoaze ja pt Lixose tr Liksoz zh ... more details
DISPLAYTITLE N Acetylmannosamine chembox Verifiedfields changed verifiedrevid 400319057 Name N Acetylmannosamine ImageFile Alfa D manosamina.png ImageSize 150px IUPACName 2 Acetylamino 2 deoxy D mannopyranose OtherNames Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 9271300 ChEMBL Ref ebicite changed EBI ChEMBL 509437 InChI 1 C8H15NO6 c1 3 11 9 5 7 13 6 12 4 2 10 15 8 5 14 h4 8,10,12 14H,2H2,1H3, H,9,11 t4 ,5 ,6 ,7 ,8 m1 s1 InChIKey OVRNDRQMDRJTHS OZRXBMAMBC StdInChI Ref stdinchicite correct chemspider StdInChI 1S C8H15NO6 c1 3 11 9 5 7 13 6 12 4 2 10 15 8 5 14 h4 8,10,12 14H,2H2,1H3, H,9,11 t4 ,5 ,6 ,7 ,8 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey OVRNDRQMDRJTHS OZRXBMAMSA N CASNo 7772 94 3 PubChem 11096158 SMILES O C H 1O C H CO C H O C H O C H 1NC C O Section2 Chembox Properties Formula C sub 8 sub H sub 15 sub NO sub 6 sub MolarMass 221.21 g mol Appearance Density MeltingPt 118 121 C BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition N Acetylmannosamine is a monosaccharide involved in a range of metabolic processes. It is an amino sugar amino acid that consists of neuraminic acid s, glycolipid s and glycoprotein s, and is used for the synthesis of sialic acid . External links http www.rspharmchem.com acetyl d mannosamine.htm Product information from R&S DEFAULTSORT Acetylmannosamine, N Category Mannosamines Category Acetamides organic compound stub es N Acetilmanosamina ... more details
italic title Taxobox color lightgrey name Mycobacterium canettii regnum Bacterium Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. canettii binomial Mycobacterium canettii binomial authority D van Soolingen, et al., 1997 Mycobacterium canettii , a novel pathogenic taxon of the Mycobacterium tuberculosis complex, was described in 1997 by D van Soolingen, et al. in International Journal of Systematic Bacteriology, 47, 1236 1245. This strain was isolated from a 2 year old Somali patient with lymphadenitis. It did not differ from Mycobacterium tuberculosis in the biochemical tests and in its 16S rRNA sequence, but formed smooth and shiny colonies, which is highly exceptional for this species. Additionally it had shorter generation time than clinical isolates of M. tuberculosis and presented a unique, characteristic phenolic glycolipid and lipo oligosaccharide. This compound was observed in a smooth isolate of M. tuberculosis described in a farmer by the French microbiologist Georges Canetti from which the organism has been named. In 1998, Pfyffer described abdominal lymphatic TB in a 56 year old Swiss man who lived in Kenya with HIV infection. Tuberculosis caused by M. canettii appears to be an emerging disease in the Horn of Africa. A history of a stay to the region should induce the clinician to consider this organism promptly even if the clinical features of TB caused by M. canettii are not specific. The natural reservoir, host range, and mode of transmission of the organism are still unknown. http www.cdc.gov ncidod eid vol8no11 02 0017 G1.htm ToLCleanup Mycobacteria Category Acid fast bacilli Category Corynebacterineae ca Mycobacterium canetti ... more details
enzyme Name galactosylceramide sulfotransferase EC number 2.8.2.11 CAS number 9081 06 5 IUBMB EC number 2 8 2 11 GO code 0001733 image width caption In enzymology , a galactosylceramide sulfotransferase EC number 2.8.2.11 is an enzyme that catalysis catalyzes the chemical reaction 3 phosphoadenylyl sulfate a galactosylceramide math rightleftharpoons math adenosine 3 ,5 bisphosphate a galactosylceramidesulfate Thus, the two substrate biochemistry substrates of this enzyme are 3 phosphoadenylyl sulfate and galactosylceramide , whereas its two product chemistry products are adenosine 3 ,5 bisphosphate and galactosylceramidesulfate . This enzyme belongs to the family of transferase s, specifically the sulfotransferases, which transfer sulfur containing groups. The systematic name of this enzyme class is 3 phosphoadenylyl sulfate galactosylceramide 3 sulfotransferase . Other names in common use include GSase , 3 phosphoadenosine 5 phosphosulfate cerebroside sulfotransferase , galactocerebroside sulfotransferase , galactolipid sulfotransferase , glycolipid sulfotransferase , and glycosphingolipid sulfotransferase . This enzyme participates in sphingolipid metabolism . References reflist 1 cite journal author McKhann GM, Levy R, Ho W date 1965 title Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides journal Biochem. Biophys. Res. Commun. volume 20 pages 109&ndash 13 pmid 5850675 doi 10.1016 0006 291X 65 90331 1 issue 2 cite journal author Sakakibara N, Gasa S, Kamio K, Makita A, Koyanagi T date 1989 title Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma journal Cancer. Res. volume 49 pages 335&ndash 9 pmid 2562926 issue 2 transferase stub Category EC 2.8.2 Category Enzymes of unknown structure ... more details
Orphan date February 2009 Peanut agglutinin PNA is plant lectin protein derived from the fruit s of Arachis hypogaea . Peanut agglutinin may also be referred to as Arachis hypogaea lectin . Lectins recognise and bind particular sugar sequences in carbohydrates peanut agglutinin binds the carbohydrate sequence Galactose Gal 1 3 N Acetylgalactosamine GalNAc . The name peanut agglutinin originates from its ability to stick together agglutinate cells, such as neuramidase treated erythrocytes ref name Medicago cite web publisher accessdate 2010 Mars 14 url http www.medicago.se sites default files pdf productsheets Arachis Hypogaea PNA v. 01.pdf title PNA specification sheet Medicago AB work ref , which have glycoprotein s or glycolipid s on their surface which include the Gal 1 3 GalNAc carbohydrate sequence. Uses in cell biology and biochemistry Because peanut agglutinin specifically binds a particular carbohydrate sequence it finds use in a range of methods for cell biology and biochemistry . For example in PNA affinity chromatography the binding specificity of peanut agglutinin is used to isolate glycosylated molecules which have the sugar sequence Gal 1 3 GalNAc. Peanut agglutinin activity is inhibited by lactose and galactose which compete for the binding site. Other uses include Potent anti T cell activity. Distinguishing between human lymphocyte subsets. Tumour tissue determination for transitional mucosa malignancies. Identification of mammalian infective metacyclic promastigote Leishmania major parasites from other life cycle forms also found in the sandfly host. biochem stub References reflist Category Plant Lectins Category Legume Lectins Category Glycoproteins ... more details
PBB geneid 653308 Neutral ceramidase B also known as non lysosomal ceramidase B or N acylsphingosine amidohydrolase non lysosomal ceramidase 2B or ASAH2B is a ceramidase enzyme which in humans is encoded by the ASAH2B gene . ref name pmid17334805 cite journal author Avramopoulos D, Wang R, Valle D, Fallin MD, Bassett SS title A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer s disease journal Neurogenetics volume 8 issue 2 pages 111 20 year 2007 month April pmid 17334805 doi 10.1007 s10048 007 0081 5 url issn ref ref name pmid15164054 cite journal author Deloukas P, Earthrowl ME, Grafham DV, et al. title The DNA sequence and comparative analysis of human chromosome 10 journal Nature volume 429 issue 6990 pages 375 81 year 2004 month May pmid 15164054 doi 10.1038 nature02462 url issn ref Clinical significance ASAH2B shows reduced expression with increasing age and further reduction in late onset Alzheimer s disease patients. ref name pmid17334805 References Reflist Further reading refbegin cite journal author Brandenberger R, Wei H, Zhang S, et al. title Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. journal Nat. Biotechnol. volume 22 issue 6 pages 707 16 year 2004 pmid 15146197 doi 10.1038 nbt971 refend Glycolipid sphingolipid metabolism enzymes gene 10 stub ... more details
Infobox journal title Glycobiology cover File Glycobiology journal .gif editor Ronald L. Schnaar discipline Biochemistry , glycobiology abbreviation Glycobiology publisher Oxford University Press country United Kingdom frequency Monthly history 1990 present openaccess license impact 3.929 impact year 2009 website http glycob.oxfordjournals.org link1 http glycob.oxfordjournals.org current.dtl link1 name Online access link2 http glycob.oxfordjournals.org archive link2 name Online archive RSS http glycob.oxfordjournals.org rss atom JSTOR OCLC 23364007 LCCN 92642337 CODEN GLYCE3 ISSN 0959 6658 eISSN 1460 2423 Glycobiology is a monthly Peer review peer reviewed scientific journal covering all aspects of the field of glycobiology and the official journal of the Society for Glycobiology . ref name oxford cite web url http glycob.oxfordjournals.org title Glycobiology publisher Oxford University Press accessdate May 21, 2010 ref The journal was established in September 1990. It publishes primary research on the biological functions of glycan s, including glycoprotein s, glycolipid s, proteoglycan s and free oligosaccharide s, and on protein proteins that specifically interact with glycans. ref name oxford Abstracting and indexing The journal is indexed in Index Medicus PubMed MEDLINE , Index Veterinarius , CAB Direct database CAB Abstracts , Biological Abstracts , BIOSIS Previews , Current Contents Life Sciences, ProQuest , Science Citation Index , and others. ref name about cite web url http www.oxfordjournals.org our journals glycob about.html title Glycobiology About the journal publisher Oxford University Press accessdate May 21, 2010 ref According to the Journal Citation Reports , its 2009 impact factor is 3.929, ranking it 78th out of 283 journals in the category Biochemistry & Molecular Biology . ref name about References reflist 2 External links Official http glycob.oxfordjournals.org Category Biochemistry journals Category English language journals Category Glycobio ... more details
Encyclopedia
top
