Globulin is one of the three types of blood plasma serum protein s, the others being serum albumin albumin and fibrinogen . Some globulins are produced in the liver, while others are made by the immune system. The term globulin encompasses a heterogeneous group of proteins with typical high molecular weight, and both solubility and electrophoretic migration rates lower than for albumin. The normal concentration in blood is 2 to 3.5 g dl. It is sometimes used synonymously with globular protein . However, albumin is also a globular protein, but not a globulin. All other serum globular proteins are globulins. Protein electrophoresis is used to categorize globulins into the following four categories Alpha 1 globulins Alpha 2 globulins Beta globulins Gamma globulins one group of gamma globulins are immunoglobulin s, that function as antibody antibodies File Blood values sorted by mass and molar concentration.png thumb 550px center Reference ranges for blood tests , comparing blood content of globulins shown in purple at right with other constituents. Pseudoglobulins and euglobulins Pseudoglobulins are a Fraction chemistry fraction of globulins that are Solution chemistry soluble in ammonium sulfate solution more so than the euglobulin fraction. Pseudoglobulins are soluble in pure water , whereas euglobulins are insoluble under the same circumstances. ref cite journal doi 10.1085 jgp.19.2.383 last Harris first1 T coauthors Eagle title The Immunological Specificity of the Euglobulin ... Category Proteins protein stub The original article states Globulin is one of the two types of serum ... , there are in fact, three types of serum proteins, including the aforementioned globulin, albumin ... Benjamin Cummings. ar ca Globulina cs Globulin de Globuline fr Globuline io Globulino lt Globulinai mk ja om Globulins nds Globulin pl Globuliny pt Globulina sq Globulina sl Globulin fi Globuliini sv Globulin th tr Globulin uk zh ... more details
Image Electrophoresis.png thumb Schematic representation of a protein electrophoresis gel Alpha Globulins are a group of globular protein s in blood plasma plasma , ref MeshName Alpha Globulins ref which are highly mobile in alkaline or electrically charged solutions. They inhibit certain blood protease and inhibitor activity. Examples Alpha 1 globulins Alpha 1 antitrypsin sub 1 sub antitrypsin Alpha 1 antichymotrypsin Orosomucoid acid glycoprotein Serum amyloid A Alpha 1 lipoprotein Alpha 2 globulins Haptoglobin Alpha 2u globulin Alpha 2 macroglobulin sub 2 sub macroglobulin Ceruloplasmin Thyroxine binding globulin Alpha 2 antiplasmin Protein C Alpha 2 lipoprotein Angiotensinogen References reflist Globulins Category Molecular biology Category Proteomics Cell biology stub protein stub es Alfa globulina it Alfa globulina ja ... more details
PBB geneid 6906 Thyroxine binding globulin TBG binds thyroid hormone in circulation. It is one of three ... cgi bin merops.cgi?id I04.955 I04.955 MeshName Thyroxine Binding Globulin Further ... sequence of human thyroxine binding globulin. Further evidence for a single polypeptide chain journal ... globulin variant TBG Kumamoto identification of a point mutation and genotype analysis of its ... globulin TBG San Diego reveals two nucleotide substitutions journal Biochim. Biophys. Acta volume ... S title Sequencing of the variant thyroxine binding globulin TBG Quebec reveals two nucleotide ... structure of rat thyroxine binding globulin journal Biochemistry volume 30 issue 22 pages 5406 11 ... Sequence of the variant thyroxine binding globulin TBG in a Montreal family with partial TBG ... as a possible cause of complete thyroxine binding globulin deficiency in six Japanese families ... binding globulin TBG deficiency caused by a single nucleotide deletion in the TBG gene journal Metab ... MR, Pullman TN, Takeda K, et al. title Molecular basis for the properties of the thyroxine binding globulin ... of Leu227 by Pro in thyroxine binding globulin TBG is associated with complete TBG deficiency ... K, Mori Y, Sobieszczyk S, et al. title Sequence of the variant thyroxine binding globulin of Australian ... activity and stability of thyroxine binding globulin probably as a result of abnormal glycosylation ... amino acid sequence of human thyroxine binding globulin deduced from cloned DNA close homology to the serine ... globulin Chicago journal J. Biol. Chem. volume 270 issue 47 pages 28234 8 year 1996 pmid 7499319 ... of the human thyroxine binding globulin gene to chromosome Xq22.2 by fluorescence in situ ... binding globulin TBG in a family with partial TBG deficiency in Japanese TBG PDJ journal Endocr ... Hayashi Y, Mori Y, Janssen OE, et al. title Human thyroxine binding globulin gene complete sequence ... The structure of the human thyroxine binding globulin TBG gene journal Biochim. Biophys. Acta volume ... more details
Drugbox drug name Zoster immune globulin type Immunoglobulin image target vaccine type CAS number ATC prefix J06 ATC suffix BB03 PubChem DrugBank pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Zoster immune globulin ZIG is a globulin fraction separable constituent of pooled mixed blood plasma plasma extracted from human donors who have recovered Citation needed date October 2009 from infection by herpes zoster . ZIG is used in the prevention of chickenpox and shingles, but is not known to be useful in treating clinical varicella or zoster ref http www.cdc.gov mmwr preview mmwrhtml rr5604a1.htm ref . References reflist Immune sera and immunoglobulins Category Polyclonal antibodies antiinfective drug stub ... more details
PBB geneid 6462 Sex hormone binding globulin SHBG or sex steroid binding globulin SSBG is a glycoprotein ... GL title Monosaccharide induced lipogenesis regulates the human hepatic sex hormone binding globulin .... A free androgen index expresses the ratio of testosterone to the sex hormone binding globulin .... Sex hormone binding globulin can be measured separate from the total fraction of testosterone ... reading citations cite journal author Hammond GL, Bocchinfuso WP title Sex hormone binding globulin ... al. title Sex hormone binding globulin mediates steroid hormone signal transduction at the plasma membrane .... title Molecular analyses of a human sex hormone binding globulin variant evidence for an additional ... Localization of the human sex hormone binding globulin gene SHBG to the short arm of chromosome ... of the human sex hormone binding globulin SHBG gene and demonstration of two transcripts in both liver ... title The human sex hormone binding globulin gene contains exons for androgen binding protein and two ... S, Fernlund P, Lundwall A title A cDNA coding for human sex hormone binding globulin. Homology to vitamin ... binding globulin and location of its steroid binding domain journal FEBS Lett. volume 215 issue 1 ... PA, Sugino H, et al. title Physicochemical characteristics of human sex hormone binding globulin ... globulin gene in heterozygous subjects journal J. Clin. Endocrinol. Metab. volume 80 issue 4 pages ... sex hormone binding globulin steroid transport by a laminin G like domain journal EMBO J. volume ... author Hogeveen KN, Talikka M, Hammond GL title Human sex hormone binding globulin promoter activity ... DJ, Nakhla AM, Kahn SM, et al. title Sex hormone binding globulin in the human prostate is locally ... MG, Hammond GL, et al. title O Glycosylation of human sex hormone binding globulin is essential ... region at the entrance of the human sex hormone binding globulin steroid binding site journal ... of common variants in the SHBG gene affecting sex hormone binding globulin levels and breast cancer ... more details
Anti lymphocyte globulin ALG is an infusion of horse derived or more commonly rabbit derived antibody antibodies against human T cell s which is used in the treatment of Transplant rejection acute rejection in organ transplant ation, especially in kidney transplants. It was developed at the University of Minnesota by Dr. John Najarian . It has also been used in the treatment of aplastic anemia . ref name pmid16126887 cite journal author Kaya B, Davies CE, Oakervee HE, Silver NC, Gawler J, Cavenagh JD title Guillain Barr syndrome precipitated by the use of antilymphocyte globulin in the treatment of severe aplastic anaemia journal J. Clin. Pathol. volume 58 issue 9 pages 994 5 year 2005 month September pmid 16126887 pmc 1770826 doi 10.1136 jcp.2004.020354 url http jcp.bmj.com cgi pmidlookup?view long&pmid 16126887 ref It is less commonly used than the similar anti thymocyte globulin ATG , and like ATG it is associated with cytokine release syndrome in the short term and an increased risk of post transplant lymphoproliferative disorder in the long term. ALG is more likely to cause Adverse effect medicine side effects than ATG, but is safer than OKT3 . One notable source of ALG was a horse called Volcano, who lived in South America. ref name pmid10705153 cite journal author Heimpel H title Aplastic anemia before bone marrow transplantation and antilymphocyte globulin journal Acta Haematol. volume 103 issue 1 pages 11 5 year 2000 pmid 10705153 doi 10.1159 000040998 url http content.karger.com produktedb produkte.asp?typ fulltext&file aha03011 ref At one point in the mid 1990s, the world s entire supply of ALG came from this horse. Fact date September 2008 References reflist Immunosuppressants Category Polyclonal antibodies bg ... more details
Drugbox verifiedrevid 405699234 drug name Rho D immune globulin type Immunoglobulin image target vaccine type CAS number ATC prefix J06 ATC suffix BB01 PubChem DrugBank pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category C legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration intramuscular injection Rh sub o sub D Immune Globulin is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rhesus disease or hemolytic disease of newborn . The medicine is a solution of IgG anti D anti RhD Antibody antibodies that bind to, and lead to the destruction of, fetal Rh D positive red blood cells that have passed from the Fetus Circulatory system fetal circulation to the maternal circulation. Therefore, in a Rhesus negative mother it can prevent sensitization of the maternal immune system to Rh D antigen s, which can cause rhesus disease in the current or in subsequent pregnancies. With the widespread use of Rho D Immune Globulin, Rh disease of the fetus and newborn has almost disappeared. History The first Rho D Immune Globulin treatment RhoGAM was introduced by Ortho Clinical Diagnostics, a subsidiary holding of Johnson and Johnson , and was first administered on May 29, 1968 to a woman in Teaneck, NJ. ref https www2.vaxserve.com views PDF RhoGAM ... History of HDN Treatment ref It has been estimated that with the use of Rho D Immune Globulin .... Manufacturing and viral transmission Rho D Immune Globulin is a derivative of human Blood plasma plasma ... About chromaplus.asp ChromaPlus Manufacturing Process ref Rho D immune globulin may trigger an allergic ... Globulin Human Information Site ref Use The medication has an FDA Pregnancy category Pregnancy ... new features RhoGAM.htm Product information MeshName Rho D Immune Globulin Immune sera and immunoglobulins ... more details
orphan date September 2010 VZV varicella zoster virus globulin is an immune system medication that is used mostly for Immunosuppression immunosuppressed patients. It shortens the course of Cutaneous conditions cutaneous disease and may protect against its dissemination. ref name Essential Neurology, 2005 Wilkinson, Iain and Lennox, Graham June 2005 . Essential Neurology 4th ed. . Wiley Blackwell. p. 263 ISBN 978 1 4051 1867 5. ref Varicella zoster virus is a virus in humans that causes chickenpox and Herpes zoster shingles . References Reflist Neuroscience stub Category Medical treatments ... more details
Drugbox drug name Hepatitis B immune globulin type Immunoglobulin image target Hepatitis B vaccine type CAS number ATC prefix J06 ATC suffix BB04 PubChem DrugBank pregnancy AU A B1 B2 B3 C D X pregnancy US c A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration intramuscular injection Hepatitis B immune globulin HBIG is a human immune globulin that is used to prevent the development of hepatitis B . Preparation HBIG is prepared form the blood plasma plasma of blood donor donor s who have high antibody levels of the hepatitis B surface antigen. It is extracted from the Cohn Fraction II. During the process, viruses are deactivated, and in the final steps, solvents used in the preparation are removed. The preparation is tested for absence of HIV , HCV , herpes virus , and reo virus . ref http www.talecris pi.info inserts BayHepB.pdf Product description with dose schedule Retrieved 2009 06 03 ref Indications HBIG is indicated as a postexposure prophylaxis for people at risk to develop hepatitis B because they have been recently exposed to body fluid s of individuals who have hepatitis B. This includes babies of mothers with hepatitis B, sexual partners, healthcare workers, police and fire workers, and morticians. ref http www.mayoclinic.com health drug information DR600747 Mayo Clinic Retrieved 2009 06 03 ref It provides a temporarily induced Immunity medical immunity by the transfer of immunoglobulin s. The medication is given as in intramuscular injection. Side effects include allergic reactions, backpain, general feeling of discomfort, headaches, muscle pain, nausea, and pain or bleeding at the injection site. Allergy to human immune globulin is a contraindication. HIV has never been transmitted by HBIG. ref name blue https www.blueshieldca.com hw articles hw article.jsp ... more details
disease , ref http www.cancer.gov Templates db alpha.aspx?CdrID 45600 Antithymocyte globulin entry ... Antithymocyte globulin for graft versus host disease prophylaxis in transplants from unrelated ... 16635791 doi 10.1016 j.bbmt.2005.12.034 ref A similar trial of anti lymphocyte globulin showed a trend ... with or without anti T cell globulin in haematopoietic cell transplantation from matched unrelated ... more details
Image Electrophoresis.png thumb Schematic representation of a protein electrophoresis gel Beta globulins are a group of globular protein s in blood plasma plasma that are more mobile in alkali ne or electrically charged solutions than gamma globulin s, but less mobile than alpha globulin s. Examples of beta globulins include beta 2 microglobulin plasmin ogen angiostatin s properdin sex hormone binding globulin transferrin External links http accstr.ufl.edu electro.htm Examples of Protein Electrophoretograms at ufl.edu MeshName Beta globulins Globulins Category Proteins Cell biology stub es Beta globulina ... more details
Phaseolin may refer to Phaseolin protein , the main reserve globulin in seeds of the French bean Phaseolus vulgaris L. Phaseolin pterocarpan , a phenolic compound found in the French bean Phaseolus vulgaris L. Biochemistry disambiguation ... more details
Protein Name Serpin peptidase inhibitor, clade A alpha 1 antiproteinase, antitrypsin , member 6, also Corticosteroid Binding Globulin or Transcortin image Transcortin.png caption Structure of corticosteroid binding globulin in complex with cortisol. Symbol SERPINA6 AltSymbols CBG HGNCid 1540 Chromosome 14 Arm q Band 32.1 LocusSupplementaryData ECnumber OMIM 122500 EntrezGene 866 RefSeq NM 001750 UniProt P08185 PDB Transcortin , also corticosteroid binding globulin or CBG , is officially called serpin peptidase inhibitor, clade A alpha 1 antiproteinase, antitrypsin , member 6 . It is an alpha globulin . Binding Transcortin binds several steroid hormones Cortisol . Approximately 75 of the cortisol in circulation is bound to this plasma protein. The rest is bound to serum albumin . The cortisol is thought to be biologically active only when it is not bound to transcortin. Progesterone Aldosterone 11 Deoxycorticosterone DOC Production Transcortin is produced by the liver and is regulated by estrogen s. Therefore, plasma transcortin levels increase during pregnancy , and are decreased in cirrhosis . External links MeshName Transcortin enzyme stub Carrier proteins Alpha globulins Serpins Glycoproteins category Glycoproteins de Transcortin es Globulina fijadora de cortisol fr Transcortine pt Transcortina ... more details
protein Name Androgen binding protein, Sex hormone binding globulin caption image width HGNCid 10839 Symbol SHBG AltSymbols ABP EntrezGene 6462 OMIM 182205 RefSeq NM 001040 UniProt P04278 PDB ECnumber Chromosome 17 Arm p Band 13 LocusSupplementaryData p12 Androgen binding protein ABP is a glycoprotein beta globulin produced by the Sertoli cells in the seminiferous tubules of the testis that binds specifically to testosterone T , dihydrotestosterone DHT , and 17 beta estradiol . Because ABP binds to T and DHT, these hormones are made less lipophilic and become concentrated within the luminal fluid of the seminiferous tubules. The higher levels of these hormones enable spermatogenesis in the seminiferous tubules and sperm maturation in the epididymis . ABP has the same amino acid sequence as sex hormone binding globulin SHBG the difference is the site of production and the addition of different sugar moieties. ABP contains 403 amino acids, resulting in a molecular weight of 44,533. Its gene is located on chromosome 17 . ABP s production is regulated under influence of FSH on Sertoli cell, enhanced by insulin , retinol , and testosterone . ABP may also be secreted in other organs for instance, mice produce a saliva ry ABP. See also Sex hormone binding globulin SHBG References Ensembl ENSG00000129214 External links MeshName Androgen Binding Protein Carrier proteins Category Glycoproteins ... more details
Thyroxine binding proteins is a protein which binds thyroid hormone . Examples include Thyroxine binding globulin Transthyretin Serum albumin External links MeshName Thyroxine binding proteins Glycoproteins Biochem stub Category Human proteins Category Blood proteins ... more details
PBB geneid 866 Corticosteroid binding globulin CBG also known as transcortin or serpin A6 is a protein that in humans is encoded by the SERPINA6 gene . ref name pmid3299377 cite journal author Hammond ... Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs ... an alpha globulin protein with corticosteroid binding properties. This is the major transport protein ..., Awan T, Khan MS title Identification of corticosteroid binding globulin in human milk measurement ... A Leu His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity ... binding globulin gene is located on chromosome 14q31 q32.1 near two other serine protease inhibitor ... Underhill DA, Hammond GL title Organization of the human corticosteroid binding globulin gene and analysis ... Immunochemical characterization of corticosteroid binding globulin in human bronchoalveolar fluid ... liquid partition chromatography in the simultaneous purification of sex hormone binding globulin and corticosteroid binding globulin. journal J. Chromatogr. volume 397 issue pages 419 34 year 1987 ... structural analyses of corticosteroid binding globulin. journal J. Steroid Biochem. volume ... Bardin CW, Gunsalus GL, Musto NA, et al. title Corticosteroid binding globulin, testosterone estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid ... of sex hormone binding globulin SHBG and corticosteroid binding globulin CBG in human saliva ... binding globulin CBG binding activity of human milk. journal Chronobiologia volume 9 issue ... Levels of sex hormone binding globulin SHBG and corticosteroid binding globulin CBG messenger ribonucleic ... al. title Corticosteroid binding globulin mRNA levels in human uterine endometrium. journal Steroids ... of human corticosteroid binding globulin. Differential processing and significance of carbohydrate ... binding globulin mRNA in human uterine endometrial cancers. journal Steroids volume ... more details
Microglobulin refers to a globulin of relatively small molecular weight. ref name urlDefinition microglobulin from Online Medical Dictionary cite web url http cancerweb.ncl.ac.uk cgi bin omd?microglobulin title Definition microglobulin from Online Medical Dictionary format work accessdate ref It can be contrasted to macroglobulin ., Examples include Beta 2 microglobulin Alpha 1 microglobulin References reflist Globulins Category Proteins biochemistry stub ... more details
Merge Serum protein electrophoresis discuss Talk Protein electrophoresis Merger proposal date October 2008 Image Electrophoresis.png thumb Schematic representation of a protein electrophoresis gel. Image Monoclonal gammopathy Multiple Myeloma.png thumb Serum protein electrophoresis showing a paraprotein peak in the gamma zone in a patient with multiple myeloma . In medicine , protein electrophoresis a.k.a. Immunoelectrophoresis is a method of analysing a mixture of protein s by means of gel electrophoresis , mainly in blood blood plasma serum blood plasma is not suitable . Before the widespread use of electrophoresis gels, protein electrophoresis was performed on paper sometimes in combination with paper chromatography . Interpretation There are two classes of blood protein s serum albumin and globulin . They are generally equal in proportion, but albumin is much smaller and lightly negatively charged, leading to an accumulation of albumin on the electrophoretic gel. A small band before albumin represents transthyretin also named prealbumin . Some forms of medication or body chemicals can cause their own band, usually small. Abnormal bands spikes are seen in monoclonal gammopathy of undetermined significance and multiple myeloma , and are useful in the diagnosis of these conditions. The globulin s are classified by their banding pattern with their main representatives The alpha globulin alpha band consists of two parts, 1 and 2 sub 1 sub alpha 1 antitrypsin sub 1 sub antitrypsin , sub 1 sub acid glycoprotein. sub 2 sub haptoglobin , alpha 2 macroglobulin sub 2 sub macroglobulin , Alpha 2 antiplasmin sub 2 sub antiplasmin , ceruloplasmin . The beta globulin beta band transferrin , LDL , complement system complement The Gamma globulin gamma band immunoglobulin IgA, IgD, IgE, IgG and IgM . Paraprotein s in multiple myeloma usually appear in this band. See also Affinity electrophoresis Electroblotting Electrofocusing Gel electrophoresis Immunofixation ... more details
ALG may refer to Algebra Algeria A League , domestic football league in Australasia Algonquian languages , from its ISO 639 code American Laser Games Americans for Limited Government Anti lymphocyte globulin , an immunosuppressive drug Application level gateway Association of London Government Houari Boumedienne Airport , Algiers, Algeria, from its IATA airport code Advanced Landing Ground , tactical airfield created by the Allies in World War II Art. Lebedev Group, the holding company which owns Art. Lebedev Studio ALG Advanced Landing Ground Wormhout disambig de ALG eo ALG fa ALG fr ALG it ALG lv ALG ja ALG zh ALG ... more details
CBG may refer to Cambridge Airport , England IATA code Cambridge railway station , England National Rail station code Cannabigerol , a non psychoactive cannabinoid found in Cannabis Carrier battle group CBG AM , a CBC Radio One station in Gander, Canada CB Richard Ellis , which uses the NYSE ticker symbol CBG Centraal Bureau voor Genealogie , the Dutch research centre for genealogy Central Bank of The Gambia Cigar box guitar Communist Bulletin Group Transcortin Corticosteroid binding globulin Comic Book Guy , character on The Simpsons Comics Buyer s Guide disambig DEFAULTSORT Cbg Category Broadcast call sign disambiguation pages de CBG fr CBG it CBG nl CBG ... more details
wiktionary zig Zig may refer to Z , Baku , Azerbaijan Zig Talmud , a giant rooster from Judaism. People One half of Australian comedy duo Zig and Zag Australian performers . Zig Ziglar , American self help author and speaker. Glenn Danzig , American musician. Z i G , American musician. In fiction One of the main characters from the French comic strip Zig et Puce One half of the puppet comedy duo Zig and Zag puppets . The space ship from the video game Zero Wing Zigs film Zigs film , a 2001 gambling film directed by Mars Callahan Other Zoster immune globulin See also Zig zag disambiguation disambig it ZIG ... more details
Image IgM scheme.svg thumb IgM , pictured, is an example of a macroglobulin. Another example is alpha 2 macroglobulin . A macroglobulin is a blood protein plasma globulin of high molecular weight . ref name urlDefinition macroglobulin from Online Medical Dictionary cite web url http cancerweb.ncl.ac.uk cgi bin omd?macroglobulin title Definition macroglobulin from Online Medical Dictionary format work accessdate ref Elevated levels of macroglobulins macroglobulinemia may cause manifestations of excess blood viscosity as is the case for IgM antibodies in Waldenstr m macroglobulinemia and or precipitate within blood vessels when temperature drops as in cryoglobulinaemia . Other macroglobulins include alpha 2 macroglobulin , which is elevated in nephrotic syndrome , diabetes , severe burns, and other conditions, while a deficiency is associated with chronic obstructive pulmonary disease . References reflist External links MeshName Macroglobulins protein stub Globulins Category Blood proteins ... more details
The Tygerberg score is a clinical decision tool that allows the clinician to decide whether pericarditis is due to tuberculosis or not. It uses five variables Weight loss 1 point Night sweats 1 point Fever 2 points Serum globulin > 40 g l 3 points Blood leukocyte count < 10 × 10 sup 9 sup l A total score of 6 or more is highly suggestive that tuberculosis is the cause of the pericarditis. References cite journal author Reuter H, Burgess L, van Vuuren W, Doubell A. title Diagnosing tuberculous pericarditis journal Q J Med year 2006 volume 99 pages 827&ndash 39 pmid 17121764 issue 12 doi 10.1093 qjmed hcl123 Category Tuberculosis Category Medical scales ... more details
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