- Endolysin
Orphan date December 2009 Endolysin is a generic term describing an enzyme that degrades the bacterial peptidoglycan cell wall, resulting in lysis of the bacterial cell. ref Young, R. 1992 Bacteriophage lysis mechanism and regulation. Microbiol. Rev. 56 430 81. ref At the end of the bacteriophage replication cycle, bacteriophages have to release their newly formed Progeny genetic descendant progeny . The major barrier to overcome is the peptidoglycan . To degrade this layer, bacteriophages contain endolysins. Depending on the bond these enzymes cleave, we can distinguish muramidase s lysozyme , transglycosylase s, amidase s or endopeptidase s. References references Category Bacteriophages Category Microbiology Enzyme stub ... more details
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- Lambda phage
. R is an endolysin , an enzyme that escapes through the S holes and cleaves the cell wall ... the endolysin has degraded the cell wall. For wild type lambda, lysis occurs at about 50 minutes after ... more details
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- Secretion
for endolysin export to the cell wall. ref name WooldridgeK See also Secretory protein s References ... more details
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- Phage therapy
engineered bacteriophages which have had their gene responsible for producing endolysin removed ... more details
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- List of glycoside hydrolase families
3.2.1.17 . This family includes lambda phage lysozyme and Escherichia coli endolysin. ref name PUB00003216 ... acid in peptidoglycan heteropolymers of prokaryotic cell walls. E. coli endolysin also functions ... more details
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