PBB geneid 1840 Protein deltex 1 is a protein that in humans is encoded by the DTX1 gene . ref name pmid9590294 cite journal author Matsuno K, Eastman D, Mitsiades T, Quinn AM, Carcanciu ML, Ordentlich P, Kadesch T, Artavanis Tsakonas S title Human deltex is a conserved regulator of Notch signalling journal Nat Genet volume 19 issue 1 pages 74 8 year 1998 month May pmid 9590294 pmc doi 10.1038 ng0598 74 ref ref name entrez cite web title Entrez Gene DTX1 deltex homolog 1 Drosophila url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 1840 accessdate ref The PBB Summary template is automatically maintained by Protein Box Bot. See Template PBB Controls to Stop updates. PBB Summary section title summary text Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch signaling pathway. The human gene encodes a protein of unknown function however, it may play a role in basic helix loop helix transcription factor activity. ref name entrez cite web title Entrez Gene DTX1 deltex homolog 1 Drosophila url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 1840 accessdate ref Interactions DTX1 has been shown to Protein protein interaction interact with EP300 . ref name pmid11564735 cite journal last Yamamoto first N authorlink coauthors Yamamoto S, Inagaki F, Kawaichi M, Fukamizu A, Kishi N, Matsuno K, Nakamura K, Weinmaster G, Okano H, Nakafuku M year 2001 month Nov. title Role of Deltex 1 as a transcriptional regulator downstream of the Notch receptor journal J. Biol. Chem. volume 276 issue 48 pages 45031 40 publisher location United States issn 0021 9258 pmid 11564735 doi 10.1074 jbc.M105245200 bibcode oclc id url language format accessdate laysummary laysource laydate quote ref References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Gerhard DS, Wagner ... characterization, and mapping to the Noonan syndrome critical region of the human Deltex DTX1 ... more details