Chembox verifiedrevid 396320598 Reference ref name sgma Name cis Cycloheptene ImageFile Cycloheptene.svg ImageSize 100px ImageFile2 Cis cycloheptene3D.png ImageSize2 200px IUPACName Z Cycloheptene OtherNames cis Cycloheptene Section1 Chembox Identifiers ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 11857 InChI 1 C7H12 c1 2 4 6 7 5 3 1 h1 2H,3 7H2 InChIKey ZXIJMRYMVAMXQP UHFFFAOYAQ StdInChI Ref stdinchicite correct chemspider StdInChI 1S C7H12 c1 2 4 6 7 5 3 1 h1 2H,3 7H2 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey ZXIJMRYMVAMXQP UHFFFAOYSA N CASNo Ref cascite correct CAS CASNo 628 92 2 PubChem 12363 SMILES C 1 C CCCCC 1 Section2 Chembox Properties Formula C sub 7 sub H sub 12 sub MolarMass 96.17 g mol Appearance Density 0.824 g cm sup 3 sup MeltingPt BoilingPt 112 114.7 C Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cycloheptene is a 7 ... in polymer synthesis. Cycloheptene can exist as either the cis trans isomerism cis or the trans ... Cycloheptene align center trans Cycloheptene trans Cycloheptene With cycloheptene, the cis isomer ... cycloheptene is by singlet photosensitivity Interpretation in chemistry photosensitization of cis cycloheptene with methyl benzoate and ultraviolet light at 35 C. ref name Squillacote The double ... of 30 kcal mol 125 kJ mol present in the trans isomer, trans cycloheptene should be a stable molecule ... that trans cycloheptene isomerization occurs by an alternative lower energy pathway. ref name ..., two trans cycloheptene molecules in the proposed pathway first form a radical chemistry diradical ... and in the final step the dimer is cleaved again into two cis cycloheptene molecules. Note that the photoisomerization ... Reflist refs ref name sgma http www.sigmaaldrich.com catalog search ProductDetail ALDRICH 141720 Cycloheptene ... of trans cycloheptene, trans cycloheptene oxide, and trans bicyclo 5.1.0 octane by ab initio calculations ... Is trans Cycloheptene? J. Am. Chem. Soc. 2005 127 45 pp 15983 15988 Article DOI 10.1021 ja055388i http ... more details
DISPLAYTITLE C sub 7 sub H sub 12 sub The molecular formula C sub 7 sub H sub 12 sub may refer to Cycloheptene Methylenecyclohexane Norbornane Norcarane MolFormDisambig nl C7H12 ... more details
Orphan date February 2009 image right Cyproheptadine.svg 180 Cyproheptadine double image right Amitriptylin.svg 180 Nortriptyline.svg 180 Amitriptyline Nortriptyline Benzocycloheptenes are cycloheptene s with additional benzene rings attached. Most have two benzene rings, and are called dibenzocycloheptenes . Some benzocycloheptenes have medical uses as antihistamines or antidepressants . Examples include Antihistamines Cyproheptadine Antidepressants Amitriptyline Nortriptyline External links MeshName Benzocycloheptenes aromatic stub Category Dibenzocycloheptenes ... more details
Chembox ImageFile Dibenzocycloheptene.png ImageSize IUPACName 10,11 dihydro 5 H dibenzo a,d 7 annulene OtherNames 10,11 dihydro 5 H dibenzo a,d cycloheptene Section1 Chembox Identifiers CASNo 833 48 7 PubChem 70029 ChemSpiderID 63219 SMILES c1cc3c cc1 Cc2c cccc2 CC3 InChI InChI 1S C15H14 c1 3 7 14 11 15 8 4 2 6 13 15 10 9 12 14 5 1 h1 8H,9 11H2 Section2 Chembox Properties Formula C sub 15 sub H sub 14 sub MolarMass 194.27 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Dibenzocycloheptene is a chemical compound featuring two benzene functional group ring s bound to a cycloheptene functional group group . Various tricyclic antidepressant s TCAs contain the dibenzocycloheptene functional group moiety in their chemical structure s, including amineptine , amitriptyline , amitriptylinoxide , butriptyline , demexiptiline , nortriptyline , noxiptiline , and protriptyline . Image Amitriptyline.svg thumb left 150px Amitriptyline See also Dibenzazepine Dibenzothiazepine Dibenzothiepin External links MeshName Dibenzocycloheptenes Tricyclics Category Tricyclic antidepressants Category Dibenzocycloheptenes hydrocarbon stub ... more details
Unreferenced stub auto yes date December 2009 A cycloalkene or cycloolefin is a type of alkene hydrocarbon which contains a closed ring of carbon atom s, but has no aromaticity aromatic character. Some cycloalkenes, such as cyclobutene and cyclopentene , can be used as monomer s to produce polymer chains. Examples gallery Image Cyclopropene 2D skeletal.svg Cyclopropene Image Cyclobutene.svg Cyclobutene Image Cyclopentene.svg Cyclopentene Image cyclohexene.png Cyclohexene Image Cycloheptene.svg Cycloheptene Image 1 3 cyclohexadiene.png 1,3 Cyclohexadiene Image 1 4 cyclohexadiene.png 1,4 Cyclohexadiene Image 1,5 Cyclooctadiene.svg 1,5 Cyclooctadiene gallery See also Olefin cycloalkyne Cycloalkane Hydrocarbons Cycloalkenes Category Cycloalkenes Orgchem stub ar ca Cicloalqu de Cycloalkene es Cicloalqueno fr Cycloalc ne hu Cikloalk nek nl Cycloalkeen ja pl Cykloalkeny pt Cicloalceno sk Cykloalk n sv Cykloalken zh ... more details
Image Cyclopropane.png thumb 150px right Cyclopropane is the smallest alicyclic compound. An alicyclic compound is an organic compound that is both Aliphatic compound aliphatic and cyclic compound cyclic . They contain one or more all carbon rings which may be either saturation chemistry saturated or unsaturated, but do not have aromaticity aromatic character. ref GoldBookRef title Alicyclic compounds file A00216 year 1995 ref Alicyclic compounds may or may not have aliphatic side chains attached. The simplest alicyclic compounds are the monocyclic cycloalkane s cyclopropane , cyclobutane , cyclopentane , cyclohexane , cycloheptane , cyclooctane , cyclononane , cyclodecane , cycloundecane , cyclododecane , and so on. Bicyclic molecule Bicyclic alkanes include bicycloundecane and decalin . Polycyclic compound Polycyclic alkanes include cubane , basketane , and housane . Spiro compound s have two or more rings that are connected through only one carbon atom. An exocyclic group is always shown outside the ring structure, take for instance the exocyclic double bond on the left Image Exocyclic.png 200px Left exocyclic double bond Right regular double bond br style clear both See for an example isotoluene . The placement of double bonds in many alicyclic compounds can be predicted with Bredt s rule . The mode of ring closing in the formation of many alicyclic compounds can be predicted by Baldwin s rules . Cycloalkenes Image Cyclohexene.png thumb right Cyclohexene is an alicyclic compound with a double bond. Monocyclic cycloalkene s are cyclopropene , cyclobutene , cyclopentene , cyclohexene , cycloheptene , cyclooctene , and so on. Bicyclic alkenes include norbornene and norbornadiene . References references Category Organic compounds Category Organic chemistry ar de Alicyclische Verbindungen el fa he hu Aliciklusos vegy let nl Alicyclische verbinding ja pt Composto alic clico sl Alicikl ... more details
chembox verifiedrevid 399914697 ImageFile ecgonidine.png ImageSize 120px IUPACName 8 Methyl 8 azabicyclo 3.2.1 oct 3 ene 4 carboxylic acid OtherNames Anhydroecgonine Section1 Chembox Identifiers InChI 1 C8H11NO2 c10 8 11 6 3 1 5 2 4 7 6 9 5 h3,5,7,9H,1 2,4H2, H,10,11 t5 ,7 m1 s1 InChIKey ZAZOGAHQAWUCJK IYSWYEEDBT SMILES1 OC O C2 C C C H 1CC C H 2N1 StdInChI Ref stdinchicite correct chemspider StdInChI 1S C8H11NO2 c10 8 11 6 3 1 5 2 4 7 6 9 5 h3,5,7,9H,1 2,4H2, H,10,11 t5 ,7 m1 s1 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey ZAZOGAHQAWUCJK IYSWYEEDSA N CASNo 484 93 5 PubChem 101709 ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 16735787 SMILES CN1C2CCC1C CC2 C O O Section2 Chembox Properties Formula C sub 9 sub H sub 13 sub NO sub 2 sub MolarMass 167.205 g· mol sup &minus 1 sup Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Ecgonidine anhydroecgonine is an alkaloid related to ecgonine and cocaine . It has a structure with a cycloheptene ring, with a nitrogen bridge, and a carboxylic acid side chain . Methylecgonidine is produced by pyrolysis in the process of smoking crack cocaine , and then subsequently metabolised to ecgonidine, and so these two compounds can be tested for as a specific biomarker for crack cocaine use. ref Scheidweiler KB, Shojaie J, Plessinger MA, Wood RW, Kwong TC. Stability of methylecgonidine and ecgonidine in sheep plasma in vitro. Clinical Chemistry. 2000 Nov 46 11 1787 95. ref Ecgonidine is formed as a metabolite of methylecgonidine, and so the relative concentrations of the two compounds can be used to gauge how recently crack cocaine was smoked. If levels of methylecgonidine are higher, then the drug was smoked recently however after a longer time period mainly ecgonidine will be present. ref Paul BD, McWhorter LK, Smith ML. Electron ionization mass fragmentometric detection of urinary ecgonidine, a hydrolytic product of methylecgonidine ... more details
chembox Reference ref http www.sigmaaldrich.com catalog search ProductDetail ALDRICH 125482 cis Cyclooctene at Sigma Aldrich ref Name cis small top small and trans Cyclooctene ImageFile Cycooctene Isomers Structural Formulae.png ImageSize 200px IUPACName E Cyclooctene br Z Cyclooctene OtherNames cis Cyclooctene br trans Cyclooctene Section1 Chembox Identifiers ChemSpiderID 553642 InChI 1 C8H14 c1 2 4 6 8 7 5 3 1 h1 2H,3 8H2 b2 1 InChIKey URYYVOIYTNXXBN UPHRSURJBT CASNo 931 87 3 PubChem 638079 SMILES C 1 C CCCCCC 1 Section2 Chembox Properties C 8 H 14 Appearance Density 0.846 g mL MeltingPtC 16 BoilingPt 145 146 C Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Cyclooctene is a cycloalkene with an eight membered ring. It is notable because it is the smallest cycloalkene that can exist as either the cis trans isomerism cis or trans isomer with the cis isomer more common. Its most stable cis conformer is shaped like a crown ether with alternating equatorial and axial hydrogens very much like the chair conformation of cyclohexane its most stable trans conformer is shaped like the 8 carbon equivalent chair conformation of cyclohexane. class wikitable Image Cis cyclooctene3D.png 150px align right Image Trans cyclooctene3D.png 150px align center cis Cyclooctene trans Cyclooctene clear left trans Cyclooctene trans Cyclooctene is the smallest cycloalkene in which the trans isomer is stable at room temperature trans cycloheptene and trans cyclohexene can exist, but they are very unstable at room temperature . This is because with trans cycloalkenes, more carbon atoms are needed to bridge the two allyl allylic carbon s than in cis cycloalkenes, because they are farther away. Therefore, four carbon atoms is the least number of carbon atoms to bridge allylic carbon atoms bonded to the same double bond without incurring significant angle strain , which corresponds to trans ... more details
Image Epoxide generic.png thumb right A generic epoxide. An epoxide is a cyclic ether with three ring atoms. This ring approximately defines an equilateral triangle , which makes it highly ring strain strained . The strained ring makes epoxides more reactive than other ethers. Simple epoxides are named from the parent compound ethylene oxide or oxirane, such as in chloromethyloxirane . As a functional group epoxides feature the epoxy prefix such as in the compound 1,2 epoxycycloheptane which can also be called cycloheptene epoxide , or simply cycloheptene oxide . Image Glycidol.svg thumb right The chemical structure of the epoxide glycidol , a common chemical intermediate A polymer containing unreacted epoxide units is called a polyepoxide or an epoxy . Epoxy resins are used as adhesive s and structural materials. Polymerization of an epoxide gives a polyether , for example ethylene oxide polymerizes to give polyethylene glycol , also known as polyethylene oxide. Synthesis The dominant epoxides industrially are ethylene oxide and propylene oxide , which are produced respectively on the scales of approximately 15 and 3 million tonnes. ref name Ullmann Siegfried Rebsdat, Dieter Mayer Ethylene Oxide in Ullmann s Encyclopedia of Industrial Chemistry, Wiley VCH, Weinheim, 2005. DOI 10.1002 14356007.a10 117 Article Online Posting Date March 15, 2001. ref The epoxidation of ethylene involves its catalytic reaction of oxygen according to the following stoichiometry 7 H sub 2 sub C CH sub 2 sub 6 O sub 2 sub 6 C sub 2 sub H sub 4 sub O 2 CO sub 2 sub 2 H sub 2 sub O The direct reaction of oxygen with alkenes is useful only for this epoxide. Other alkenes fail to react usefully, even propylene . Olefin peroxidation Most epoxides are generated by treating alkene s with peroxide containing reagents, which donate a single oxygen atom. Typical peroxide reagents include hydrogen peroxide, peroxycarboxylic acids generated in situ or preformed , and alkyl hydroperoxides. In speciali ... more details
Pyramidal alkenes are alkene s in which the two carbon atom s making up the double bond are not coplanar with their four substituent s Ref . This deformation from a trigonal planar geometry to a tetrahedral molecular geometry is the result of angle strain induced in the molecule due to geometric constraints. Pyramidal alkenes only exist in the laboratory but are of interest because much can be learned from them about the nature of chemical bond ing ref Chemistry of pyramidalized alkenes Santiago V zquez, and Pelayo Camps Tetrahedron Volume 61, Issue 22, 30 May 2005 , Pages 5147 5208 DOI 10.1016 j.tet.2005.03.055 ref . In cycloheptene 1.1 the cis isomer is an ordinary unstrained molecule but the heptane ring is too small to accommodate a trans configured alkene group resulting in strain and twisting of the double bond. The p orbital misalignment is minimized by a degree of pyramidalization . In the related anti bredt molecule s it is not pyrimidalization but twisting that dominates. Image Cagealkenes.png center 300px Fig. 1 Pyramidal alkenes Pyramidalized cage alkenes also exist where symmetrical bending of the substituents predominates without p orbital misalignment. Image Anglestraindefinition.png center 400px Fig. 2 Angle definitions The pyramidalization angle math phi math b is defined as the angle between the plane defined by one of the doubly bonded carbons and its two substituents and the extension of the double bond and is calculated as math cos phi cos R C C cos 1 2 R C R math the butterfly bending angle or folding angle math psi math c is defined as the angle between two planes and can be obtained by averaging the two torsional angle s R1C CR3 and R2C CR4. In alkenes 1.2 and 1.3 these angles are determined with x ray crystallography as respectively 32.4 22.7 and 27.3 35.6 . Although stable, these alkenes are very reactive compared to ordinary alkenes. They are liable to dimerization to cyclobutadiene compounds or react with oxygen to epoxide s. The compound ... more details
See also List of UN Numbers UN 2201 to UN 2300 class wikitable width 140px UN Number Class Proper Shipping Name UN 2201 2 Nitrous oxide , refrigerated liquid UN 2202 2 Hydrogen selenide , anhydrous UN 2203 2 Silane , compressed UN 2204 2 Carbonyl sulfide UN 2205 6.1 Adiponitrile UN 2206 6.1 Isocyanate s, toxic, n.o.s. or Isocyanate solutions, toxic, n.o.s. flashpoint more than 61 C and boiling point less than 300 C UN 2208 5.1 Calcium hypochlorite mixtures, dry, with more than 10 percent but not more than 39 percent available chlorine UN 2209 8 Formaldehyde , solutions, with not less than 25 percent formaldehyde UN 2210 4.2 Maneb or Maneb preparations with not less than 60 percent maneb UN 2211 9 Polymer ic beads, expandable, evolving flammable vapor UN 2212 9 Blue asbestos Crocidolite or Brown asbestos amosite , mysorite UN 2213 4.1 Paraformaldehyde UN 2214 8 Phthalic anhydride with more than .05 percent maleic anhydride UN 2215 8 Maleic anhydride UN 2216 9 Fish meal , stabilized or Fish scrap, stabilized UN 2217 4.2 Seed cake with not more than 1.5 percent oil and not more than 11 percent moisture UN 2218 8 Acrylic acid , inhibited UN 2219 3 Allyl glycidyl ether UN 2222 3 Anisole UN 2224 6.1 Match es, Flare pyrotechnic fusee or Benzonitrile UN 2225 8 Benzenesulfonyl chloride UN 2226 8 Benzotrichloride UN 2227 3 n Butyl methacrylate , inhibited UN 2232 6.1 2 Chloroethanal UN 2233 6.1 Chloroanisidine s UN 2234 3 Chlorobenzotrifluoride s UN 2235 6.1 Chlorobenzyl chloride s UN 2236 6.1 3 Chloro 4 methylphenyl isocyanate UN 2237 6.1 Chloronitroaniline s UN 2238 3 Chlorotoluene s UN 2239 6.1 Chlorotoluidine s liquid or Chlorotoluidines solid UN 2240 8 Chromosulfuric acid UN 2241 3 Cycloheptane UN 2242 3 Cycloheptene UN 2243 3 Cyclohexyl acetate UN 2244 3 Cyclopentanol UN 2245 3 Cyclopentanone UN 2246 3 Cyclopentene UN 2247 3 n Decane UN 2248 8 Di n butylamine UN 2249 6.1 Dichlorodimethyl ether , symmetrical UN 2250 6.1 Dichlorophenyl isocyanate s UN 2251 3 Bicyclo 2,2,1 ... more details
Drugbox IUPAC name 3 10,11 dihydro 5 H dibenzo a,d cycloheptene 5 ylidene N , N dimethyl 1 propanamine N oxide image Amitriptylinoxide.png InChI 1 C20H23NO c1 21 2,22 15 7 12 20 18 10 5 3 8 16 18 13 14 17 9 4 6 11 19 17 20 h3 6,8 12H,7,13 15H2,1 2H3 smiles O N C C CC C C2 c1c cccc1 CCc3c2cccc3 InChIKey ZPMKQFOGINQDAM UHFFFAOYAS ChEMBL 627 StdInChI 1S C20H23NO c1 21 2,22 15 7 12 20 18 10 5 3 8 16 18 13 14 17 9 4 6 11 19 17 20 h3 6,8 12H,7,13 15H2,1 2H3 StdInChIKey ZPMKQFOGINQDAM UHFFFAOYSA N CAS number 4317 14 0 ATC prefix none ATC suffix PubChem 20313 ChemSpiderID 19137 KEGG D07449 chemical formula C sub 20 sub H sub 23 sub NO molecular weight 293.40 g mol bioavailability metabolism elimination half life excretion pregnancy category legal status Rx only routes of administration Oral Amitriptylinoxide Amioxid , Ambivalon , Equilibrin , or amitriptyline N oxide , is a tricyclic antidepressant TCA which was introduced in Europe in the 1970s for the treatment of Major depressive disorder depression . ref name isbn3 88763 075 0 cite book author Swiss Pharmaceutical Society title Index Nominum 2000 International Drug Directory Book with CD ROM publisher Medpharm Scientific Publishers location Boca Raton year 2000 page 49 pages 1932 isbn 3 88763 075 0 oclc doi url http books.google.com ?id 5GpcTQD L2oC&lpg PA49&dq amitriptylinoxide&pg PA49 v onepage&q &f false ref Amitriptylinoxide is both an Structural analog analogue and metabolite of amitriptyline , and has similar effects as well as equivalent efficacy as an antidepressant. ref name pmid360779 cite journal author Rapp W title Comparative trial of amitriptyline N oxide and amitriptyline in the treatment of out patients with depressive syndromes journal Acta Psychiatrica Scandinavica volume 58 issue 3 pages 245 55 year 1978 month September pmid 360779 doi 10.1111 j.1600 0447.1978.tb06936.x url ref ref name pmid cite journal author Tegeler J, Klieser E, Lehmann E, Heinrich K title Double blind study of the therapeutic ... more details
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