image Chromosome 16.svg 125px right Chromosome16 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome16 spans about 90 million base pair s the building material of DNA and represents just under 3 of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome16 probably contains between 850 and 1,200 genes. In February 2010, a new cause of obesity due to a microdeletion on chromosome16 was announced. It may explain about 1 of obesity cases. This research was carried out by Professor Froguel, a CNRS researcher, in Lille, and others at Imperial College in London and Vaudois University and was published in Nature on February 4, 2010. This defect was identified using DNA microarrays and it leads to the suppression of about thirty genes in one region of chromosome16. Research showed that this microdeletion is relatively common in obese people but lacking in most non obese people. Diseases and Disorders Trisomy 16 Familial Mediterranean fever FMF Crohn s disease Thalassemia External links http www.ncbi.nlm.nih.gov bookshelf br.fcgi ... cite journal author Gilbert F title Disease genes and chromosomes disease maps of the human genome. Chromosome16 journal Genet Test year 1999 pages 243 54 volume 3 issue 2 pmid 10464676 cite journal author Martin J, et al. title The sequence and analysis of duplication rich humanchromosome16 journal ... DEFAULTSORT Chromosome16Human Category Chromosomes genetics stub ca Cromosoma 16 de Chromosom 16 Mensch es Cromosoma 16 humano fr Chromosome16 humain it Cromosoma 16 umano hu Hum n 16 os kromosz ma nl Chromosoom 16 no Kromosom 16 pl Chromosom 16 pt Cromossoma 16 humano ro Cromozomul uman 16 ru 16 sr 16 fi Kromosomi 16 tr Kromozom 16 ... more details
Image Chromosome 8.svg right Chromosome 8 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 8 spans about 145 million base pair s the building material of DNA and represents between 4.5 and 5.0 of the total DNA in cell biology cells . ref name Tabares Seisdedos The chromosome has two arms, 8p and 8q. The short arm, 8p, has about 45 million base pairs, about 1.5 of the genome, and includes 484 genes and 110 pseudogene s about 8 of its genes are involved in brain development and function, and about 16 are involved in cancer . A unique feature of 8p is a big region of about 15 megabases that appears to have a high mutation rate, and which shows an immense divergence between human and chimpanzee , suggesting that its high mutation rates have contributed to the evolution of the human brain. ref name Tabares Seisdedos cite journal author Tabar s Seisdedos R, Rubenstein JL title Chromosome 8p as a potential hub for developmental neuropsychiatric disorders implications for schizophrenia, autism and cancer journal Mol Psychiatry volume 14 issue 6 pages 563 89 year 2009 pmid 19204725 doi 10.1038 mp.2009.2 ref Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome ... Nusbaum C et al. title DNA sequence and analysis of humanchromosome 8 journal Nature year 2006 pages ... on chromosome 8 AEG1 Astrocyte Elevated Gene linked to hepatocellular carcinoma and neuroblastoma ... L gulonolactone oxidase GULOP pseudogene responsible for human inability to produce our own Vitamin C Diseases & disorders The following diseases are some of those related to genes on chromosome ... References reflist 2 cite journal author Gilbert F title Chromosome 8 journal Genet Test year ... Chromosome 08 genetics stub ca Cromosoma 8 de Chromosom 8 Mensch es Cromosoma 8 humano fr Chromosome ... more details
image Chromosome 15.jpeg right frame Humanchromosome 15 Chromosome 15 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 15 spans about 106 ... of DNA on humanchromosome 15 could lead to two different syndromes depending on whether the deletion originated from the mother or the father and explains that this was the first human evidence that something ... in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 15 likely contains between 700 and 900 genes. Genes The following are some of the genes located on chromosome 15 CAPN3 Calpain 3 limb girdle muscular dystrophy ..., E. coli S. cerevisiae STRC stereocilin UBE3A ubiquitin protein ligase E3A human papilloma virus ... are caused by mutations in chromosome 15. Two of the conditions Angelman syndrome and Prader Willi syndrome involve a loss of gene activity in the same part of chromosome 15, the 15q11 q13 region ... episodes Season 35 2007 2008 Ghost in Your Genes season 35 date October 16, 2007 accessdate 2009 ... of gene activity in a specific part of chromosome 15, the 15q11 q13 region. This region contains ... in the maternal copy of chromosome 15. This chromosomal change deletes the region of chromosome ... the paternal copy is normally inactive in the brain, a deletion in the maternal chromosome 15 ... September 2009 Angelman syndrome occurs when a person has two copies of the paternal chromosome 15 ... with paternal UPD for chromosome 15 have two copies of the UBE3A gene, but they are both inherited ... the activation of the UBE3A gene and other genes on the maternal copy of chromosome 15. In a small ... Prader Willi syndrome is caused by the loss of active genes in a specific part of chromosome 15, the 15q11 q13 region. People normally have two copies of this chromosome in each cell, one ... more details
A human artificial chromosome HAC is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6 10 base pair megabases in size, and able to carry new genes introduced by human researchers. Yeast artificial chromosome s and bacterial artificial chromosome s were created before human artificial chromosomes, which first appeared in 1997 in science 1997 . They are useful in expression studies as gene transfer Vector molecular biology vector s and are a tool for elucidating humanchromosome function. Grown in HT1080 cells, they are mitosis mitotically and cytogenetics cytogenetically stable for up to six months. History John J. Harrington , Gil Van Bokkelen , Robert W. Mays , Karen Gustashaw & Huntington F. Willard of Case Western Reserve University School of Medicine published the first report of human artificial chromosomes in 1997. They were first synthesized by combining portions of alpha satellite DNA with telomere telomeric DNA and genomic DNA into linear microchromosomes. See also bacterial artificial chromosome BAC yeast artificial chromosome YAC plasmid cosmid fosmid References http www.nature.com ng journal v15 n4 abs ng0497 345.html Formation of de novo centromeres and construction of first generation human artificial microchromosomes in Nature Genetics 15, 345 355 1997 Harrington and Bokkelen et al. Category Molecular biology Nucleic acids genetics stub biotech stub ca Cromosoma artificial hum es Cromosoma artificial humano pl Ludzki sztuczny chromosom zh ... more details
Image Chromosome 20.svg 125px right Chromosome 20 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 20 spans around 63 million base pair s the building material of DNA and represents between 2 and 2.5 percent of the total DNA in cell biology cells . Chromosome 20 was fully sequenced in 2001 and contained 59,187,298 base pairs representing 99.4 of the euchromatic DNA. ref name Deloukas2001 cite journal author Deloukas P, et al. title The DNA sequence and comparative analysis of humanchromosome 20 journal Nature year 2001 pages 865 871 volume 414 issue 6866 pmid 11780052 doi 10.1038 414865a ref Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Citation needed date April 2009 Chromosome 20 contains over 900 genes. New discoveries When date February 2011 have recently linked this chromosome to the increasing susceptibility to male pattern baldness. Citation needed date April 2009 Genes The following are some of the genes located on chromosome 20 EDN3 endothelin 3 JAG1 jagged 1 Alagille syndrome PANK2 pantothenate kinase 2 Hallervorden Spatz syndrome PRNP prion protein p27 30 Creutzfeld Jakob disease, Gerstmann Strausler Scheinker syndrome, fatal familial insomnia tTG tissue transglutaminase Celiac disease Adenosylhomocysteinase AHCY S adenosylhomocysteine hydrolase ... ideogr,est,loc&LINKS ON&VERBOSE ON&CHR 20 HumanChromosome 20 Map Viewer &mdash on NCBI Chromosomes DEFAULTSORT Chromosome 20 Human Category Chromosomes genetics stub bg 20 ca Cromosoma 20 de Chromosom 20 Mensch es Cromosoma 20 humano fr Chromosome 20 humain it Cromosoma 20 umano ... & disorders The following diseases are some of those related to genes on chromosome 20 ref name Gilbert1997 cite journal author Gilbert F title Disease genes and chromosomes disease maps of the human ... more details
Image chromosome 2.svg 125px right Chromosome 2 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 2 is the second largest humanchromosome .... Humans have only 23 pairs of chromosomes. Humanchromosome 2 is widely accepted to be a result of an end to end fusion of two ancestral chromosomes. ref name fusion http www.evolutionpages.com chromosome 2.htm HumanChromosome 2 is a fusion of two ancestral chromosomes by Alec MacAndrew accessed 18 May 2006. ref ref http www.youtube.com watch?v x WAHpC0Ah0 Evidence of Common Ancestry HumanChromosome ... of chromosome 2 to two ape chromosomes. The closest human relative, the chimpanzee , has near identical DNA sequences to humanchromosome 2, but they are found in two separate chromosomes ... on the long arm of humanchromosome 2 journal Human Genetics year 1992 pages 247 9 volume 89 pmid .... ref name telomeres cite journal author IJdo et al. title Origin of humanchromosome 2 an ancestral ... fused to give rise to humanchromosome 2. ref name telomeres Genes The following genes are located ... Recent studies suggest that genes on chromosome 2 may play an important role in human intelligence ... 2010 DEFAULTSORT Chromosome 2 Human Category Chromosomes Chromosome 02 Category Human evolution .... title Generation and annotation of the DNA sequences of human chromosomes 2 and 4 journal Nature year ... and representing almost 8 of the total DNA in cell biology cells . Identifying gene s on each chromosome ... the number of genes on each chromosome, the estimated number of genes varies. Chromosome 2 likely contains ... Homo sapiens mapview?chr 2 Vega Homo sapiens Overview of Chromosome 2 Bot generated title ref Evolution further Chimpanzee Genome Project Genes of the Chromosome 2 fusion site Genes of the Chromosome ... ref ref name similarities http www.gate.net rwms hum ape chrom.html Human and Ape Chromosomes accessed 8 September 2007. ref The presence of a Vestigial structure vestigial centromere . Normally a chromosome ... more details
image Chromosome 18.svg 125px right Chromosome 18 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 18 spans about 76 million base pair s the building material of DNA and represents about 2.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 18 likely contains between 300 and 400 genes. Genes The following are some of the genes located on chromosome 18 FECH ferrochelatase protoporphyria NPC1 Niemann Pick disease, type C1 SMAD4 SMAD, mothers against DPP homolog 4 Drosophila yes, SMAD really does contain mothers against KC6 Keratoconus gene 6, discovery reported in 2005 Diseases & disorders The following diseases are some of those related to genes on chromosome 18 erythropoietic protoporphyria hereditary hemorrhagic telangiectasia Niemann Pick disease Type C porphyria Selective Mutism Edwards syndrome Edwards syndrome Trisomy 18 Tetrasomy 18p Monosomy 18p Pitt Hopkins Syndrome Pitt Hopkins Syndrome 18q21 References cite journal author Nusbaum C, Zody MC, Borowsky ML, Kamal M, Kodira CD, Taylor TD, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Abouelleil A, Allen NR, Anderson S, Bloom T, Bugalter B, Butler J, Cook A, DeCaprio D, Engels R, Garber M, Gnirke A, Hafez N, Hall JL, Norman CH, Itoh T, Jaffe DB, Kuroki Y, Lehoczky J, Lui A, Macdonald P, Mauceli E, Mikkelsen TS, Naylor JW ... ES title DNA sequence and analysis of humanchromosome 18 journal Nature year 2005 pages 551 ... title Trapping and sequence analysis of 1138 putative exons from humanchromosome 18 journal Mol Psychiatry ... author Gilbert F title Disease genes and chromosomes disease maps of the human genome. Chromosome ... Chromosom 18 Mensch es Cromosoma 18 humano fr Chromosome 18 humain it Cromosoma 18 umano hu Hum n 18 ... more details
annotation of humanchromosome 1 journal Nature volume 441 issue 7091 pages 315 21 year 2006 month May pmid 16710414 doi 10.1038 nature04727 ref Identifying gene s on each chromosome is an active area of genetics genetic research . Chromosome 1 is currently believed to have 4,220 genes, exceeding previous predictions based on its size. ref name vega It was the last completed chromosome, sequenced two decades after the beginning of the Human Genome Project . The number of single nucleotide ..., mild According to http www.ornl.gov sci techresources Human Genome posters chromosome chromo01.shtml the Chromosome 1 contains 263 million base pairs Diseases & disorders There are 890 known diseases related to this chromosome. Some of these diseases are deafness, Alzheimer disease, glaucoma and breast cancer. Rearrangements and mutations of chromosome 1 are prevalent in cancer and many other ... s of any humanchromosome 1q21.1 deletion syndrome 1q21.1 duplication syndrome Alzheimer disease ..., Fronicke L, O Brien SJ, Stanyon R title The origin of humanchromosome 1 and its homologs in placental ... PS title Report and abstracts of the sixth international workshop on humanchromosome 1 mapping 2000 ... 4994088.stm Final genome chapter published BBC NEWS Chromosomes DEFAULTSORT Chromosome 1 Human ...Image Chromosome 1.svg thumb Map of Chromosome 1 alt Map of Chromosome 1 125px right Chromosome 1 is the designation for the largest humanchromosome . Humans have two copies of chromosome 1, as they do with all of the autosome s, which are the non sex chromosome s. Chromosome 1 spans about 247 million ... Homo sapiens mapview?chr 1 Chromosome size and number of genes derived from this database, retrieved May 31, 2008. ref It represents about 8 of the total DNA in human cells. ref name pmid16710414 ... Genes The following are some of the genes located on chromosome 1 p arm Image Chromarms.gif thumb ... contribute to human fitness, and also in regions where no function is evident. The following diseases ... more details
File NF2.PNG 91px right Chromosome 22 is one of the 23 pairs of chromosome s in human s. Humans normally have two copies of Chromosome 22. Chromosome 22 is the second smallest humanchromosome, spanning ... AM, Buck D, Burgess J, Burrill WD, O Brien KP title The DNA sequence of humanchromosome 22 ... author Gilbert F title Disease genes and chromosomes disease maps of the human genome. Chromosome ... activity of humanChromosome 22 journal Genes Dev year 2003 pages 529 40 volume 17 issue 4 pmid ... DNA in cell biology cells . In 1999 , researchers working on the Human Genome Project announced they had determined the sequence of base pairs that make up this chromosome. Fact date February 2009 Chromosome 22 was the first humanchromosome to be fully sequenced. Fact date February 2009 Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 22 contains about 693 genes. Fact date February 2009 Chromosome 22 was originally identified as the smallest chromosome, but after extensive research, researchers concluded that it was indeed chromosome 21. The chromosomes weren t renamed because of the popularity of chromosome 21 being known as the chromosome that can lead to Down s Syndrome . For this reason, researchers did not rearrange the numbers on these chromosomes. Genes The following are some of the genes located on chromosome ... The following diseases are some of those related to genes on chromosome 22 Amyotrophic lateral ... or number of copies of chromosome 22 22q11.2 deletion syndrome Most people with 22q11.2 deletion syndrome are missing about 3 million base pairs on one copy of chromosome 22 in each cell. The deletion occurs near the middle of the chromosome at a location designated as q11.2. This region ... tip of the chromosome 22 is related to moderate to severe developmental delay and mental ... more details
image Chromosome 11.svg thumb right Chromosome 11 Chart Chromosome 11 is one of the 23 pairs of chromosome s in human s. Humans normally have two copies of this chromosome. Chromosome 11 spans about 134.5 million base pair s the building material of DNA and represents between 4 and 4.5 percent of the total DNA in cell biology cells . It is one of the most gene and disease rich chromosomes in the human genome . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 11 likely contains between 1,300 and 1,700 genes. A recent study ref cite journal author Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y title Humanchromosome 11 DNA sequence ... measurements megabase , including 1,524 protein coding genes and 765 pseudogene s can be found on chromosome 11. More than 40 of the 856 olfactory receptor genes in the human genome are located in 28 single and multi gene clusters along this chromosome. Genes The following are some of the genes located on chromosome 11 ACAT1 acetyl Coenzyme A acetyltransferase 1 acetoacetyl Coenzyme A thiolase APOA4 ... The following diseases are some of those related to genes on chromosome 11 autism autism neurexin 1 ... Romano Ward syndrome Sickle cell anemia ref http www.ornl.gov sci techresources Human Genome posters chromosome hbb.shtml ref Smith Lemli Opitz syndrome tetrahydrobiopterin deficiency Usher syndrome ... genes and chromosomes disease maps of the human genome journal Genet Test year 2000 pages 409 26 volume ... stub ca Cromosoma 11 de Chromosom 11 Mensch es Cromosoma 11 humano fr Chromosome 11 humain it Cromosoma ... more details
Chromosome 21 is one of the 23 pairs of chromosomes in human s. People normally have two copies of this chromosome. The trisomy of the 21st chromosome causes Down s Syndrome . Chromosome 21 is the smallest humanchromosome, spanning 47 million nucleotide s the building material of DNA and representing about 1.5 percent of the total DNA in cell biology cells . In 2000, researchers working on the Human Genome Project announced that they had determined the sequence of base pair s that make up this chromosome. Chromosome 21 was the second humanchromosome to be fully sequenced. Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 21 likely contains between 300 and 400 genes. Genes The following are some of the genes located on chromosome ... S0959 437X 00 00185 4 cite journal author Gardiner K, Davisson M title The sequence of humanchromosome ... Gilbert F title Disease genes and chromosomes disease maps of the human genome. Chromosome 21 journal ... R, Yaspo ML title The DNA sequence of humanchromosome 21 journal Nature year 2000 pages 311 ... on chromosome 21 Alzheimer s disease Alzheimer s disease type 1 Amyotrophic lateral sclerosis Amyotrophic ... by changes in the structure or number of copies of chromosome 21 Cancer s Rearrangements Chromosomal translocation translocations of genetic material between chromosome 21 and other chromosomes have ... of chromosomal material between chromosome 21 and another chromosome. As a result, a person has the usual two copies of chromosome 21, plus extra material from chromosome 21 attached to another chromosome. These cases are called translocation Down syndrome. Researchers believe that extra copies of genes on chromosome 21 disrupt the course of normal development, causing the characteristic .... Other changes in the number or structure of chromosome 21 can have a variety of effects, including ... more details
image Chromosome 9.svg 125px right Chromosome 9 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome, as they normally do with all chromosomes. Chromosome 9 spans about 145 million base pair s of nucleic acids the building blocks of DNA and represents between 4 and 4.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 9 likely contains between 800 and 1,200 genes. Genes The following are some of the genes located on chromosome 9 ABO blood group system ABO ABO histo blood group glycosyltransferases ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ALAD aminolevulinate, delta , dehydratase ALS4 amyotrophic lateral sclerosis 4 ASS gene ASS argininosuccinate synthetase CCL21 chemokine C C motif ligand 21, SCYA21 CCL27 chemokine C C motif ligand 27, SCYA27 COL5A1 collagen, type V, alpha 1 ENG gene ENG endoglin Osler Rendu Weber syndrome 1 FXN frataxin GALT gene GALT galactose 1 phosphate uridylyltransferase ... DNA sequence and analysis of humanchromosome 9 journal Nature year 2004 pages 369 74 volume 429 issue ... t Diseases & disorders The following diseases are some of those related to genes on chromosome 9 acytosiosis ... cite journal author Gilbert F, Kauff N title Disease genes and chromosomes disease maps of the human genome. Chromosome 9 journal Genet Test year 2001 pages 157 74 volume 5 issue 2 pmid 11551106 ..., Wainwright B title Fine genetic mapping of the gene for nevoid basal cell carcinoma syndrome. Chromosome ... L title The assignment the lethal congenital contracture syndrome LCCS locus to chromosome 9q33 34 journal ... stub Chromosomes Category Chromosomes Chromosome 09 ca Cromosoma 9 de Chromosom 9 Mensch es Cromosoma 9 humano fr Chromosome 9 humain it Cromosoma 9 umano hu Hum n 9 es kromosz ma nl Chromosoom 9 no Kromosom ... more details
About a chromosome the novel of the same name Chromosome 6 novel Image Chromosome 6.svg 125px right Chromosome 6 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pair s the building material of DNA and represents between 5.5 and 6 of the total DNA in cell biology cells . It contains the Major Histocompatibility Complex , which contains over 100 genes related to the immune response , and plays a vital role in organ transplantation . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 1,100 and 1,600 genes. Citation needed date February 2007 Genes The following are some of the genes located on chromosome 6 BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide maple syrup urine disease CNR1 cannabinoid 1 receptor ref Matsuda, L A, S J Lolait, M J Brownstein, A C Young, and T I Bonner. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature, 1990 346 561 564. ref COL11A2 collagen, type XI, alpha 2 CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide ... related to genes on chromosome 6 ankylosing spondylitis , HLA B collagenopathy, types II and XI Coeliac ... was taken from http ghr.nlm.nih.gov chromosome 6 public domain cite journal author Gilbert F title Chromosome 6 journal Genet Test year 2002 pages 341 58 volume 6 issue 4 pmid 12537662 doi 10.1089 10906570260471912 cite journal author Mungall AJ et alii title The DNA sequence and analysis of humanchromosome 6 journal Nature year 2003 pages 805 11 volume 425 issue 6960 pmid 14574404 doi 10.1038 nature02055 Chromosomes Category Chromosomes Chromosome 06 genetics stub bs Hromozom 6 ovjek ca Cromosoma 6 de Chromosom 6 Mensch es Cromosoma 6 humano fr Chromosome 6 humain it Cromosoma 6 umano ... more details
Image Chromosome 7.svg 125px right Chromosome 7 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 7 spans more than 158 million base pair ... EE, Green ED, Waterston RH, Wilson RK title The DNA sequence of humanchromosome 7 journal Nature ... Humanchromosome 7 DNA sequence and biology journal Science year 2003 pages 767 72 volume 300 issue ... cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 7 is likely to contain between 1,000 and 1,400 genes. It also contains ... to genes on chromosome 7 argininosuccinic aciduria cerebral cavernous malformation Charcot Marie ... are caused by changes in the structure or number of copies of chromosome 7 Williams syndrome is caused by the deletion of genetic material from a portion of the long q arm of chromosome 7. The deleted ... syndrome is unknown. Other changes in the number or structure of chromosome 7 can cause delayed ..., delayed speech, and other medical problems. These changes include an extra copy of part of chromosome 7 in each cell partial trisomy 7 or a missing segment of the chromosome in each cell partial monosomy 7 . In some cases, several DNA building blocks nucleotides are deleted or duplicated in part of chromosome 7. A circular structure called ring chromosome 7 is also possible. A ring chromosome occurs when both ends of a broken chromosome are reunited. References div class references small cite journal author Gilbert F title Chromosome 7 journal Genet Test year 2002 pages 141 61 volume 6 issue ... chromosome 7 mosaicism case report, investigation of the gene content, and delineation of the phenotype ... SM, Kukolich MK, Lockhart LH, Tonk VS title De novo supernumerary ring chromosome 7 first report ... Chromosomes Chromosome 07 ca Cromosoma 7 de Chromosom 7 Mensch es Cromosoma 7 humano fr Chromosome ... more details
image Chromosome 14.jpeg right Chromosome14 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 14 spans about 109 million base pair s the building material of DNA and represents between 3 and 3.5 of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 14 likely contains between 700 and 1,300 genes. Genes The following are some of the genes located on chromosome 14 COCH coagulation factor C homolog, cochlin Limulus polyphemus GALC galactosylceramidase Krabbe disease GCH1 GTP cyclohydrolase 1 dopa responsive dystonia IGH antibody immunoglobulin heavy chain locus NPC2 Niemann Pick disease, type C2 PSEN1 presenilin 1 Alzheimer disease 3 SERPINA1 serpin peptidase inhibitor, clade A alpha 1 antiproteinase, antitrypsin , member 1 TSHR thyroid stimulating hormone receptor Diseases & disorders The following diseases are some of those related to genes on chromosome 14 alpha 1 antitrypsin deficiency Alzheimer disease Alzheimer disease, type 3 congenital hypothyroidism dopamine responsive dystonia Krabbe disease Machado Joseph disease multiple myeloma Niemann Pick disease nonsyndromic deafness nonsyndromic deafness, autosomal dominant tetrahydrobiopterin deficiency Uniparental disomy UPD 14 References cite journal author Campo ... and chromosomes disease maps of the human genome. Chromosome 14 journal Genet Test year 1999 pages ... The DNA sequence and analysis of humanchromosome 14 journal Nature year 2003 pages 601 7 volume ... Current status of humanchromosome 14 journal J Med Genet year 2002 pages 81 90 volume 39 issue 2 ... of the chromosome 14q terminal deletion syndrome journal Am J Med Genet year 2002 pages 65 72 volume ... Cromosoma 14 de Chromosom 14 Mensch es Cromosoma 14 humano fr Chromosome 14 humain it Cromosoma 14 ... more details
Image Chromosome 13.jpeg right Chromosome 13 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 13 spans about 114 million base pair s the building material of DNA and represents between 3.5 and 4 of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 13 likely contains between 300 and 700 genes. Fact date October 2008 Genes The following are some of the genes located on chromosome 13 ATP7B ATPase, Cu transporting, beta polypeptide Wilson disease BRCA2 breast cancer 2, early onset CARKD Carbohydrate Kinase Domain Containing ... and analysis of humanchromosome 13 journal Nature year 2004 pages 522 8 volume 428 issue 6982 pmid 15057823 doi 10.1038 nature02379 pmc 2665288 cite journal author Gilbert F title Chromosome 13 journal ... of those related to genes on chromosome 13 Bladder cancer Breast cancer Heterochromia Hirschsprung s disease ... by changes in the structure or number of copies of chromosome 13 Retinoblastoma A small percentage of retinoblastoma cases are caused by deletions in the region of chromosome 13 13q14 containing the RB1 ... 13 Trisomy 13 occurs when each cell in the body has three copies of chromosome 13 instead of the usual two copies. Trisomy 13 can also result from an extra copy of chromosome 13 in only some of the body ... of chromosomal material between chromosome 13 and another chromosome. As a result, a person has the two usual copies of chromosome 13, plus extra material from chromosome 13 attached to another chromosome. These cases are called translocation trisomy 13. Extra material from chromosome 13 disrupts ... that results when a piece of the long arm q of chromosome 13 is missing monosomic . Infants born ... de Chromosom 13 Mensch es Cromosoma 13 humano fr Chromosome 13 humain it Cromosoma 13 umano hu Hum n ... more details
group c Chromosomes DEFAULTSORT Chromosome 3 Human Category Chromosomes Chromosome 03 ca Cromosoma 3 de Chromosom 3 Mensch es Cromosoma 3 humano et 3. kromosoom fr Chromosome 3 humain ...Unreferenced date December 2009 Image Chromosome 3.svg 125px right Image Chromarms.gif thumb Short and long arms Chromosome 3 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 3 spans almost 200 million base pair s the building material of DNA and represents about 6.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 3 likely contains between 1,100 and 1,500 genes. Genes Expand list date August 2008 The following are some of the genes located on chromosome 3 p arm ALAS1 aminolevulinate, delta , synthase 1 BTD biotinidase CCR5 chemokine C C motif receptor 5 CNTN4 Contactin 4 COL7A1 Collagen, type VII, alpha 1 epidermolysis bullosa, dystrophic, dominant and recessive MITF microphthalmia associated transcription factor MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 E. coli OXTR oxytocin receptor PTHR1 parathyroid hormone receptor 1 SCN5A sodium channel , voltage gated, type V, alpha long QT syndrome 3 SLC25A20 solute carrier family 25 carnitine acylcarnitine translocase , member 20 TMIE transmembrane inner ear VHL von Hippel Lindau tumor suppressor q arm CPOX coproporphyrinogen oxidase coproporphyria, harderoporphyria HGD homogentisate 1,2 dioxygenase homogentisate oxidase MCCC1 methylcrotonoyl Coenzyme A carboxylase 1 alpha PCCB propionyl Coenzyme A carboxylase, beta polypeptide PDCD10 programmed ... Expand list date August 2008 The following diseases are some of those related to genes on chromosome ... Charcot Marie Tooth disease, type 2 Charcot Marie Tooth disease Chromosome 3q duplication syndrome ... more details
File Chromosome 12.svg 125px right Chromosome 12 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 12 spans about 143 million base pair s the building material of DNA and represents between 4 and 4.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 12 likely contains between 1,000 and 1,300 genes. It also contains the Homeobox C gene cluster. Genes The following are some of the genes located on chromosome 12 Obed M. Ha ACVRL1 activin A receptor type II like 1 heterochromatin protein 1 CBX5 chromobox homolog 5 COL2A1 collagen, type II, alpha 1 primary osteoarthritis, spondyloepiphyseal dysplasia, congenital HPD gene HPD 4 hydroxyphenylpyruvate dioxygenase KERA gene KERA keratocan LRRK2 leucine rich repeat kinase 2 MMAB methylmalonic aciduria cobalamin dewrong ficiency cblB type MYO1A myosin IA Nanog transcription factor NANOG NK 2 type homeodomain gene PAH gene PAH phenylalanine hydroxylase PPP1R12A protein phosphatase 1, regulatory inhibitor subungfdit 12A PTPN11 protein tyrosine phosphatase, non receptor type 11 Noonan syndrome 1 KRAS V Ki ras2 Kirsten rat sarcoma viral oncogene homolog Diseases & disorders The following diseases are some of those related to genes on chromosome 12 achondrogenesis type 2 collagenopathy, types II and XI cornea plana 2 hereditary hemorrhagic telangiectasia hypochondrogenesis ... map of humanchromosome 12 journal Nature year 2001 pages 945 6 volume 409 issue 6822 pmid 11237017 ... S, Ahmad J, et al. title Genomewide significant linkage to stuttering on chromosome 12 journal ... Gilbert F, Kauff N title Disease genes and chromosomes disease maps of the human genome.Chromosome ... Mensch es Cromosoma 12 humano fr Chromosome 12 humain it Cromosoma 12 umano hu Hum n 12 es kromosz ma ... more details
Image Chromosome 5.svg 125px right Chromosome 5 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 5 spans about 181 million base pair s the building blocks of DNA and represents almost 6 of the total DNA in cell biology cells . Chromosome 5 is one of the largest human chromosomes, yet has one of the lowest gene densities. This is partially ... The DNA sequence and comparative analysis of humanchromosome 5 journal Nature year 2004 pages 268 ... constrained. ref http genome.jgi psf.org chr5 chr5.home.html ref Identifying gene s on each chromosome ... the number of genes on each chromosome, the estimated number of genes varies. Chromosome 5 likely contains between 900 and 1,300 genes. Genes The following are some of the genes located on chromosome ... are some of the diseases related to genes located on chromosome 5 Achondrogenesis type 1B ... or number of copies of chromosome 5 Cri du chat syndrome is caused by a deletion of the end of the short p arm of chromosome 5. This chromosomal change is written as 5p . The signs and symptoms ... narrow regions of the short arm of chromosome 5 that are associated with particular features of cri ... polyposis coli APC tumor suppressor gene on the long q arm of chromosome 5. This chromosomal ... colectomy is not done. Other changes in the number or structure of chromosome 5 can have a variety ..., and other medical problems. Changes to chromosome 5 include an extra segment of the short p or long q arm of the chromosome in each cell partial trisomy 5p or 5q , a missing segment of the long arm of the chromosome in each cell partial monosomy 5q , and a circular structure called ring chromosome 5. A ring chromosome occurs when both ends of a broken chromosome are reunited. References reflist ... F title Chromosome 5 journal Genet Test year 2003 pages 169 87 volume 7 issue 2 pmid 12885343 doi ... Chromosomes Category Chromosomes Chromosome 05 ca Cromosoma 5 de Chromosom 5 Mensch es Cromosoma ... more details
image Chromosome 17.svg 125px right Chromosome 17 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 17 spans more than 81 million base pair s the building material of DNA and represents between 2.5 and 3 of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 17 likely contains between 1,200 and 1,500 genes. It also contains the Homeobox B gene cluster. Genes The following are some of the genes located on chromosome 17 ACADVL acyl coenzyme A dehydrogenase, very long chain ACTG1 actin, gamma 1 ASPA gene ASPA aspartoacylase Canavan disease BRCA1 breast cancer 1, early onset CBX1 chromobox homolog 1 COL1A1 collagen, type I, alpha 1 CTNS gene CTNS cystinosin, the lysosomal cystine transporter ERBB2 loca leukemia viral oncogene homolog 2, neuro glioblastoma derived oncogene homolog avian FLCN folliculin GALK1 galactokinase 1 Glial fibrillary acidic protein GFAP glial fibrillary acidic protein KCNJ2 potassium inwardly rectifying channel, subfamily J, member 2 MYO15A myosin XVA Neurofibromin 1 NF1 neurofibromin 1 neurofibromatosis , von Recklinghausen disease, Watson disease PMP22 peripheral myelin protein 22 SHBG Sex hormone binding globulin SLC6A4 Serotonin transporter TMC6 and TMC8 Transmembrane channel like 6 and 8 epidermodysplasia verruciformis TP53 tumor suppressor protein p53 Li Fraumeni syndrome , tumor suppressor ... to genes on chromosome 17 Alexander disease Andersen Tawil syndrome Birt Hogg Dub syndrome ... cite journal author Gilbert F title Disease genes and chromosomes disease maps of the human genome. Chromosome 17 journal Genet Test year 1998 pages 357 81 volume 2 issue 4 pmid 10464617 doi 10.1089 ... Mensch es Cromosoma 17 humano fr Chromosome 17 humain it Cromosoma 17 umano hu Hum n 17 es kromosz ma ... more details
image Chromosome 19.svg 125px right Chromosome 19 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 19 spans more than 63 million base pair s the building material of DNA and represents between 2 and 2.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 19 likely contains between 1,300 and 1,700 genes. Genes The following are some of the genes located on chromosome 19 A1BG Plasma glycoprotein, unknown function. Gene map locus 19q13.43 Apolipoprotein E APOE Apolipoprotein E, gene associated with Alzheimer s disease BCKDHA Branched chain keto acid dehydrogenase E1, alpha polypeptide maple syrup urine disease CACNA1A Calcium channel, voltage dependent, P Q type, alpha 1A subunit, mutations of which are associated with Familial hemiplegic migraine Type I DMPK Dystrophia myotonica protein kinase EYCL1 EYE COLOR ... author Gilbert F title Disease genes and chromosomes disease maps of the human genome. Chromosome ... and biology of humanchromosome 19 journal Nature year 2004 pages 529 35 volume 428 issue 6982 pmid ... The following diseases are some of those related to genes on chromosome 19 Alzheimer s disease ... type 6 X linked agammaglobulinemia or Bruton s Disease Proteins The Human Proteome Project HPP has been initiated by Human Proteome Organization HUPO aims to sequence the entire human proteome based ... sharing of proteome datasets. The proteome sequencing has been initiated with a chromosome centric and gene centric approach. Sequencing of chromosome 19 proteome will be coordinated by Prof. Gy rgy ... Outreach seehear spring01 lebers.htm Human Proteome Project Launch website http www.hupo.org ... 19 de Chromosom 19 Mensch es Cromosoma 19 humano fr Chromosome 19 humain id Kromosom 19 manusia it Cromosoma ... more details
image Chromosome 10.svg 125px right Chromosome 10 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 10 spans about 135 million base pair s the building material of DNA and represents between 4 and 4.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 10 likely contains between 800 and 1,200 genes. ref http ghr.nlm.nih.gov chromosome 10 Chromosome 10 Genetics Home Reference Bot generated title ref Genes The following are some of the genes located on chromosome 10 ALOX5 Arachidonate 5 Lipoxygenase processes essential fatty acids to leukotrienes, which are important agents in the inflammatory response also facilitates development and maintenance of cancer stem cells, slow dividing cells thought to give rise to a variety of cancers, including leukemia CDH23 cadherin like 23 SDF 1 biology CXCL12 chemokine C X C motif ligand 12, SDF 1, scyb12 EGR2 early growth response 2 Krox 20 homolog, Drosophila ERCC6 excision repair cross complementing rodent repair deficiency, complementation group 6 FGFR2 fibroblast growth factor receptor 2 bacteria expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson Weiss syndrome PCBD1 6 pyruvoyl tetrahydropterin ... analysis of humanchromosome 10 journal Nature year 2004 pages 375 81 volume 429 issue ... NK title Report of the third international workshop on humanchromosome 10 mapping and sequencing ... The following diseases are some of those related to genes on chromosome 10 Apert syndrome Beare ... 10.1159 000015653 cite journal author Gilbert F title Chromosome 10 journal Genet Test year 2001 pages ... Chromosomes ca Cromosoma 10 de Chromosom 10 Mensch es Cromosoma 10 humano fr Chromosome 10 humain ... more details
image Chromosome 4.svg 125px right Chromosome 4 is one of the 23 pairs of chromosome s in human s. People normally have two copies of this chromosome. Chromosome 4 spans more than 186 million base pair s the building material of DNA and represents between 6 and 6.5 percent of the total DNA in cell biology cells . Identifying gene s on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 700 and 1,100 genes. Genes The following are some of the genes located on chromosome 4 ANK2 ankyrin 2 , neuronal CRMP1 Collapsin response mediator protein 1, a member of Collapsin response mediator protein family CRMP family CXCL1 chemokine C X C motif ligand 1, scyb1 CXCL2 chemokine C X C motif ligand 2, scyb2 CXCL3 chemokine C X C motif ligand 3, scyb3 platelet factor 4 CXCL4 chemokine C X C motif ligand 4, Platelet factor 4, PF 4, scyb4 CXCL5 chemokine C X C motif ligand 5, scyb5 CXCL6 chemokine C X C motif ligand 6, scyb6 CXCL7 chemokine C X C motif ligand 7, PPBP, scyb7 interleukin 8 CXCL8 chemokine C X C motif ligand 8, interleukin 8 IL 8 , scyb8 CXCL9 chemokine C X C motif ligand 9, scyb9 CXCL10 chemokine C X C motif ligand 10, scyb10 CXCL11 chemokine C X C motif ligand 11, scyb11 CXCL13 chemokine C X C motif ligand 13, scyb13 DUX4 Thought to be inactive but 2010 research shows a key role in FSHD ref name Unifying cite ... maps of the human genome. Chromosome 4 journal Genet Test year 2003 pages 351 72 volume 7 issue 4 ... of the diseases related to genes located on chromosome 4 achondroplasia bladder cancer Crouzonodermoskeletal ... RK title Generation and annotation of the DNA sequences of human chromosomes 2 and 4 journal Nature ... Category Chromosomes Chromosome 04 genetics stub ca Cromosoma 4 de Chromosom 4 Mensch es Cromosoma 4 humano fr Chromosome 4 humain it Cromosoma 4 umano hu Hum n 4 es kromosz ma mk ... more details
Summary US Government website http www.ornl.gov sci techresources Human Genome posters chromosome chromo21.shtml DOE Human Genome Program . No alternate copyright statement on the website nor on the poster version of same, so assumed to be US government material. Converted from Flash to png by me. Date is given as 2002. Licensing PD USGov DOE ... more details
genetic genealogy In human genetics , a Human Y chromosome DNA haplogroup is a haplogroup defined by differences in the non genetic recombination recombining portions of DNA from the Y chromosome called Y DNA . The Y chromosome consortium has established a system of defining Y DNA haplogroup s by letters ... of mtDNA and Y chromosome polymorphisms url journal European Journal of Human Genetics ... Major Y chromosome haplogroups include Tree view Clade label1 Y chromosomal Adam Y DNA Adam ... Anders last4 Holmlund first4 Gunilla author separator , author name separator year 2006 title Y chromosome diversity in Sweden A long time perspective url journal European Journal of Human Genetics ... title A novel subgroup Q5 of human Y chromosomal haplogroup Q in India journal BMC Evol Biol ... supports demic diffusion of Han culture, Nature 431, 302 305 16 September 2004 ref ref http www.pubmedcentral.nih.gov articlerender.fcgi?artid 56946&rendertype table&id T1 Table 1 Y chromosome ... Heartland A continental perspective on Y chromosome diversity, Proceedings of the National ... Y Chromosome Evidence for Differing Ancient Demographic Histories in the Americas, Maria Catira Bortolini et al., American Journal of Human Genetics 73 524 539, 2003 ref Q1a3a2 M194 Q1a3a3 M199 ... populations List of Y DNA single nucleotide polymorphisms List of Y STR markers Human mitochondrial ... table for Y chromosome haplogroups Y DNA References Reflist added under references heading by script assisted edit small note ycc http ycc.biosci.arizona.edu Y Chromosome Consortium note familytreedna http www.familytreedna.com haplotree.html 2005 Y chromosome Phylogenetic Tree , from FamilyTreeDNA.com ... for the Tree of Human Y Chromosomal Haplogroups , Genome.org small External links Commons category Human Y DNA haplogroups http www.isogg.org tree ISOGG Y DNA Haplogroup Tree http hurlbutdna.pbwiki.com ... genographic atlas.html Atlas of the Human Journey , from the Genographic Project , National ... more details
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