Search: in
Aryl hydrocarbon receptor nuclear translocator
Aryl hydrocarbon receptor nuclear translocator in Encyclopedia Encyclopedia
  Tutorials     Encyclopedia     Videos     Books     Software     DVDs  
       
Encyclopedia results for Aryl hydrocarbon receptor nuclear translocator

Aryl hydrocarbon receptor nuclear translocator





Encyclopedia results for Aryl hydrocarbon receptor nuclear translocator

  1. Aryl hydrocarbon receptor nuclear translocator

    PBB geneid 405 The ARNT gene encodes the aryl hydrocarbon receptor nuclear translocator protein that forms a complex with ligand bound aryl hydrocarbon receptor AhR , and is required for receptor function ... Recruitment of the NCoA SRC 1 p160 family of transcriptional coactivators by the aryl hydrocarbon receptor aryl hydrocarbon receptor nuclear translocator complex journal Mol. Cell. Biol. volume ... aryl hydrocarbon receptor nuclear translocator protein journal J. Biol. Chem. volume 272 issue ... Kuo M T year 1995 month Oct. title Functional analysis of aryl hydrocarbon receptor nuclear translocator interactions with aryl hydrocarbon receptor in the yeast two hybrid system journal Biochem ... receptor nuclear translocator interactions with aryl hydrocarbon receptor in the yeast two hybrid ... of functional domains of the aryl hydrocarbon receptor nuclear translocator protein ARNT . journal Mol ... Aryl Hydrocarbon Receptor Nuclear Translocator NLM content gene 1 stub Transcription factors ... elements in the promoters of genes for these enzymes. Interactions Aryl hydrocarbon receptor nuclear .... The ligand free, cytosolic form of the aryl hydrocarbon receptor is complexed to Hsp90 heat shock ... author Reyes H, Reisz Porszasz S, Hankinson O title Identification of the Ah receptor nuclear translocator .... title The Ah receptor nuclear translocator gene ARNT is located on q21 of human chromosome 1 and on mouse ..., Gustafsson JA title Trans activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor ... HI, Yang J title Mapping the protein DNA contact sites of the Ah receptor and Ah receptor nuclear translocator ... receptor nuclear translocator protein. journal J. Biol. Chem. volume 272 issue 7 pages 4451 7 year ... CA title Ligand dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin ... spliced variants encoding different isoforms have been described for this gene. The aryl hydrocarbon ... Bradfield C A year 1997 month Apr. title Ligand dependent interaction of the aryl hydrocarbon ...   more details



  1. Aryl hydrocarbon receptor repressor

    protein Name aryl hydrocarbon receptor repressor caption image width HGNCid 346 Symbol AHRR AltSymbols AHH, AHHR EntrezGene 57491 OMIM 606517 RefSeq NM 020731 UniProt Q9ULI6 PDB ECnumber Chromosome 5 Arm p Band 15.33 LocusSupplementaryData The aryl hydrocarbon receptor repressor also known as AHRR is a human gene . ref name pmid11423533 cite journal author Baba T, Mimura J, Gradin K, Kuroiwa A, Watanabe T, Matsuda Y, Inazawa J, Sogawa K, Fujii Kuriyama Y title Structure and expression of the Ah receptor repressor gene journal J. Biol. Chem. volume 276 issue 35 pages 33101 10 year 2001 month August pmid 11423533 doi 10.1074 jbc.M011497200 url ref Function Dioxin chemical Dioxin is a Teratogenesis teratogen that exerts its effects through the aryl hydrocarbon receptor AhR in conjunction with the Receptor biochemistry receptor s binding partner, aryl hydrocarbon receptor nuclear translocator ..., Birrer M, Cuttitta F title The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene ... expression of aryl hydrocarbon receptor repressor gene in human tissues organ specific distribution ... author Kanno Y, Takane Y, Izawa T, Nakahama T, Inouye Y title The Inhibitory Effect of Aryl Hydrocarbon Receptor Repressor AhRR on the Growth of Human Breast Cancer MCF 7 Cells journal Biol. Pharm. Bull ... for binding to the arylhydrocarbon receptor. ref name pmid18000031 cite journal author Evans BR, Karchner SI, Allan LL, Pollenz RS, Tanguay RL, Jenny MJ, Sherr DH, Hahn ME title Repression of aryl hydrocarbon receptor AHR signaling by AHR repressor role of DNA binding and competition for AHR nuclear translocator journal Mol. Pharmacol. volume 73 issue 2 pages 387 98 year 2008 month February pmid 18000031 doi 10.1124 mol.107.040204 url ref Expression of the repressor is stimulated by the receptor translocator protein dimer heterodimer , thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa B . The AhRR ...   more details



  1. Nuclear receptor

    magenta and two molecules of the Nuclear receptor coactivator 2 NCOA2 coactivator red . The PPAR ... s behavior is present. More specifically, ligand binding to a nuclear receptor results in a chemical ... receptors may be classified according to either Nuclear receptor Mechanism of action mechanism ref name Mangelsdorf 1995 ref name Novac 2004 or Nuclear receptor Family members homology . ref name ... nuclear receptor ligands and the name of the receptor that each binds to. Ligands that bind to and activate ... of nuclear receptors, referred to as orphan receptor s, ref name pmid17132856 have no known ... sensors. Other nuclear receptors, such as constitutive androstane receptor CAR and Pregnane ... Image Nuclear Receptor Structure.png thumb 415px Structural Organization of Nuclear Receptors br Top Schematic 1D peptide sequence amino acid sequence of a nuclear receptor. br Bottom 3D structures of the DBD bound to DNA and LBD bound to hormone regions of the nuclear receptor. The structures shown ... begin Image Nuclear receptor action.png thumb 475px Mechanism nuclear receptor action . This figure depicts the mechanism of a class I nuclear receptor NR that, in the absence of ligand biochemistry ... element HRE . The nuclear receptor DNA complex in turn recruits other protein s that are responsible ... Type ii nuclear receptor action.png thumb 475px Mechanism nuclear receptor action . This figure depicts the mechanism of a class II nuclear receptor NR , which, regardless of ligand binding status, is located in the nucleus bound to DNA. For the purpose of illustration, the nuclear receptor shown ... receptor . ref name AutoJQ 1 The nuclear receptor DNA complex chemistry complex then recruits ... to the nuclear receptor causes dissociation of corepressor and recruitment of coactivation Transcription ... of the NR subfamilies. Coregulatory proteins main nuclear receptor coregulators Nuclear receptors bound ... of agonist ligands see section below to nuclear receptors induces a conformation of the receptor that preferentially ...   more details



  1. Nuclear receptor coactivator 2

    laydate quote ref Aryl hydrocarbon receptor nuclear translocator , ref name pmid12024042 cite ... SRC 1 p160 family of transcriptional coactivators by the aryl hydrocarbon receptor aryl hydrocarbon receptor nuclear translocator complex journal Mol. Cell. Biol. volume 22 issue 12 pages 4319 ...PBB geneid 10499 The nuclear receptor coactivator 2 gene NCOA2 is a transcription coregulator transcriptional coregulatory protein which contains several nuclear receptor interacting domains and an intrinsic ... ref NCOA2 is also frequently called glucocorticoid receptor interacting protein 1 GRIP1 , steroid receptor coactivator 2 SRC 2 , or transcriptional mediators intermediary factor 2 TIF2 . Interactions Nuclear receptor coactivator 2 has been shown to Protein protein interaction interact with DDX17 ... remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams .... title Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator ... Reflist External links MeshName nuclear receptor coactivator 2 3 nuclear receptor coactivator 2 NURSA ... TIF2 contains three nuclear receptor binding motifs and mediates transactivation through CBP binding ..., Cross NC title A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid ... SM, et al. title Multiple signal input and output domains of the 160 kilodalton nuclear receptor coactivator ... nuclear receptor RORalpha. journal Mol. Endocrinol. volume 13 issue 9 pages 1550 7 year 1999 pmid ... MR title Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators ... nuclear receptors. NCOA2 in turn acylates histones which makes downsteam DNA more accessible to transcription. Hence NCOA2 assists nuclear receptors in the upregulation of DNA expression. ref name ..., a 160 kDa transcriptional mediator for the ligand dependent activation function AF 2 of nuclear receptors ... 2001 month Mar. title A subfamily of RNA binding DEAD box proteins acts as an estrogen receptor ...   more details



  1. Nuclear Receptor Signaling Atlas

    The Nuclear Receptor Signaling Atlas NURSA is a United States National Institutes of Health funded research consortium focussed on nuclear receptors and transcription coregulator nuclear receptor coregulators . ref name pmid16051673 cite journal author Margolis RN, Evans RM, O Malley BW title The Nuclear Receptor Signaling Atlas development of a functional atlas of nuclear receptors journal Mol. Endocrinol. volume 19 issue 10 pages 2433 6 year 2005 month October pmid 16051673 doi 10.1210 me.2004 0461 url ref ref name pmid16381851 cite journal author Lanz RB, Jericevic Z, Zuercher WJ, Watkins C, Steffen DL, Margolis R, McKenna NJ title Nuclear Receptor Signaling Atlas www.nursa.org hyperlinking the nuclear receptor signaling community journal Nucleic Acids Res. volume 34 issue Database issue pages D221 6 year 2006 month January pmid 16381851 pmc 1347392 doi 10.1093 nar gkj029 url ref Its co principal investigators are Bert W. O Malley Bert O Malley of Baylor College of Medicine and Ronald M. Evans Ron Evans of the Salk Institute. References Reflist External links cite web url http www.nursa.org title NURSA Nuclear Receptor Signaling Atlas author authorlink coauthors date format work publisher pages language archiveurl archivedate quote Receptors, Coactivators, Corepressors and Ligands accessdate 2008 08 27 Category Bioinformatics Category Biological databases bioinformatics stub ...   more details



  1. Nuclear receptor coregulators

    Nuclear receptor coregulators ref name Copyright This article is based on the transcript of an animated course on the Nuclear Receptor Signaling Atlas NURSA website entitled Nuclear receptor signaling ..., the Nuclear Receptor Signaling Atlas, on August 25th 2008. ref are a class of transcription coregulators that have been shown to be involved in any aspect of signaling by any member of the nuclear receptor superfamily. A comprehensive database of nuclear receptor coregulators can be found at the http www.nursa.org Nuclear Receptor Signaling Atlas website . Introduction The ability of nuclear ... nuclear receptor coactivator was steroid receptor coactivator 1, or nuclear receptor coactivator ... doi 10.1073 pnas.93.10.4948 issue 10 pmc 39385 ref and nuclear receptor coactivator 3 ACTR p CIP , initially ... D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. title Nuclear receptor coactivator ... co activator p CIP binds CBP and mediates nuclear receptor function journal Nature volume ... of 5 amino acids where L leucine and X any amino acid , or nuclear receptor box, present from a single ... on a critical conformation of the receptor AF 2 domain, as well as upon nuclear receptor box like helical ... isolated in rapid succession, nuclear receptor corepressor, or nuclear receptor co repressor 1 NCoR ... by a nuclear receptor co repressor journal Nature volume 377 pages 397 404 year 1995 pmid 7566114 ... to the coactivator nuclear receptor boxes. ref name Hu 1994 cite journal author Hu, X., and Lazar ... Rosenfeld Rosenfeld MG title Combinatorial roles of the nuclear receptor corepressor in transcription ... steady state nuclear hormone receptor coregulator complexes exist in vivo journal Proc. Natl. Acad ... receptor and coregulator action remain poorly defined, a broad composite model of nuclear receptor action invokes corepressors as critical mediators of nuclear receptor silencing. In turn, a variety ... Nuclear receptor coregulators and human disease journal Endocr Rev. volume 28 pages 575 87. year 2007 ...   more details



  1. Nuclear receptor coactivator 3

    PBB geneid 8202 The nuclear receptor coactivator 3 also known as NCOA3 is a protein that, in humans, is encoded ... that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. NCOA3 is recruited to DNA promotion sites by ligand activated nuclear receptors. NCOA3 ... assists nuclear receptor s in the upregulation of gene expression. ref name Anzick 1997 cite journal ... Interactions Nuclear receptor coactivator 3 has been shown to Protein protein interaction interact with DDX17 ... of nuclear receptor coactivators in the mouse lung journal Am. J. Physiol. Lung Cell Mol. Physiol ... mechanisms of nuclear receptor regulation by receptor associated coactivator 3 journal J. Biol ... ref References Reflist External links MeshName nuclear receptor coactivator 3 3 nuclear receptor ... amplified nuclear receptor coactivator SRC 3 AIB1. journal J. Steroid Biochem. Mol. Biol. volume ... journal author Li H, Gomes PJ, Chen JD title RAC3, a steroid nuclear receptor associated coactivator ... cite journal author Chen H, Lin RJ, Schiltz RL, et al. title Nuclear receptor coactivator ... mechanisms of nuclear receptor regulation by receptor associated coactivator 3. journal J ... fr Nuclear receptor coactivator 3 The PBB Controls template provides controls for Protein Box ... receptor coactivator amplified in breast and ovarian cancer journal Science journal volume 277 ... TRAM 1, A novel 160 kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator 1 journal J. Biol. Chem. volume 272 issue 44 pages 27629 34 year 1997 ... in breast 1 AIB1 , steroid receptor coactivator 3 SRC 3 , or thyroid hormone receptor activator ..., Trent JM, Meltzer PS title AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer ... CS, Chin WW title TRAM 1, A novel 160 kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator 1 journal J Biol Chem volume 272 issue 44 pages 27629 ...   more details



  1. Nuclear receptor coactivator 1

    PBB geneid 8648 The nuclear receptor coactivator 1 gene NCOA1 is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity EC number 2.3.1.48 . NCOA1 is recruited to DNA promotion sites by ligand activated nuclear ... month Jun. title A regulatory role for RIP140 in nuclear receptor activation journal Mol. Endocrinol .... Hence, NCOA1 assists nuclear receptors in the upregulation of DNA expression. ref name Onate ... of a coactivator for the steroid hormone receptor superfamily journal Science volume 270 issue ... BW title The steroid receptor coactivator 1 contains multiple receptor interacting and activation ... 9575154 ref NCOA1 is also frequently called steroid receptor coactivator 1 SRC 1 . External links MeshName nuclear receptor coactivator 1 3 nuclear receptor coactivator 1 NURSA C89 Interactions Nuclear receptor coactivator 1 has been shown to Protein protein interaction interact with Thyroid hormone receptor beta , ref name pmid9751500 cite journal doi 10.1210 en.139.10.4197 last Liu first Y authorlink ... role of steroid receptor coactivator 1 in ligand induced transactivation by thyroid hormone receptor ... Dec. title Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways journal ... acts as an estrogen receptor alpha coactivator through the N terminal activation domain AF 1 with an RNA ... and steroid receptor coactivators in vitamin D receptor mediated transcription journal J. Biol ... laydate quote ref Androgen receptor , ref name pmid15256534 cite journal last Masiello first David ... of the androgen receptor by interleukin 6 and the role of steroid receptor coactivator 1 in prostate ... and AF2 domains of the androgen receptor interact with distinct regions of SRC1 journal Mol. Cell ... receptor coactivator 1 SRC1 CREB binding protein interaction interface and its importance ... quote pmc 133790 ref Glucocorticoid receptor , ref name pmid11266503 cite journal doi 10.1210 me.15.4.501 ...   more details



  1. Aryl

    about the aryl organic functional group the fleshy covering of certain seeds aril In the context of organic molecules, aryl refers to any functional group or substituent derived from a simple aromatic ring , be it phenyl , thiophene thienyl , indole indolyl , etc. see IUPAC nomenclature . ref http goldbook.iupac.org A00464.html ref Aryl is used for the sake of abbreviation or generalization. A simple aryl group is phenyl , C sub 6 sub H sub 5 sub it is derived from benzene . The tolyl group, CH sub 3 sub C sub 6 sub H sub 4 sub , is derived from toluene methylbenzene . The xylyl group, CH sub 3 sub sub 2 sub C sub 6 sub H sub 3 sub , is derived from xylene dimethylbenzene . Image Aryl groups.PNG thumb center 500 px Several types of benzene derived aryl groups. From left to right phenyl , benzyl , tolyl, o xylyl . Biaryls may display axial chirality . Arylation is simply any chemical process in which an aryl group is attached to a substrate. See also Alkyl Aryl hydrocarbon receptor , a bodily target for Dioxins and dioxin like compounds dioxin s ref name pmid16545780 cite journal author Bock KW, K hle C title Ah receptor dioxin mediated toxic responses as hints to deregulated physiologic functions journal Biochem. Pharmacol. volume 72 issue 4 pages 393 404 year 2006 pmid 16545780 doi 10.1016 j.bcp.2006.01.017 ref Arene compound References Reflist Category Aryl groups Category Substituents aromatic stub ar cs Aryl de Arylgruppe et Ar lr hm es Grupo arilo fr Aryle it Arile hu Arilcsoport mk nl Arylgroep ja pl Grupa arylowa pt Arila ru sv Arylgrupp uk zh ...   more details



  1. Hydrocarbon

    chemistry are as follows Saturated hydrocarbons alkane s are the simplest of the hydrocarbon species ... 978 3 54 076885 2 ref Unsaturated hydrocarbon s have one or more double or triple bonds between ... atoms are attached. The general formula for a saturated hydrocarbon containing one ring is C sub n sub H sub 2n sub . ref name Silderberg, 625 Aromatic hydrocarbon s, also known as arene s, are hydrocarbons ... due to the self bonding or catenation of carbon preventing entire saturation of the hydrocarbon ... is referred to as catenation , and allows hydrocarbon to form more complex molecules, such as cyclohexane ... gas . The hydrocarbon is burnt and the heat is used to heat water, which is then circulated. A similar ... for combustion to take place. The simplest hydrocarbon, methane, burns as follows CH sub 4 ... for the production of organic chemistry organic chemicals . The extraction of liquid hydrocarbon ... of Hydrocarbons The Prohibition of Hydrocarbon Genesis at Low Pressures. accessdate 2006 ... the mantle to the crust, at shallow levels, microorganisms invade the hydrocarbon accumulations, feed ... Biohydrocarbon Energy storage Fractional distillation Functional group Hydrocarbon mixtures Hydrocarbons ... ca Hidrocarbur cs Uhlovod ky cy Hydrocarbon da Kulbrinte de Kohlenwasserstoffe et S sivesinikud ... simple Hydrocarbon sk Uh ovod k sl Ogljikovodik sr su Hidrokarbon fi Hiilivety sv Kolv te ...   more details



  1. Nuclear receptor co-repressor 2

    , Hoivik D, Lee JE, Safe S title Interactions of nuclear receptor coactivator corepressor proteins with the aryl hydrocarbon receptor complex. journal Arch. Biochem. Biophys. volume 367 issue 2 pages ...PBB geneid 9612 The nuclear receptor co repressor 2 gene NCOR2 is a transcription coregulator transcriptional coregulatory protein which contains several nuclear receptor interacting domains. In addition ... repression domains as well as two or three C terminus C terminal nuclear receptor interacting domains ... D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM title Nuclear receptor repression mediated ... reported in a variant referred to as TRAC 1. ref name Sande 1996 Interactions Nuclear receptor co repressor ... R, Jameson J L year 1998 month Dec. title The interaction of the vitamin D receptor with nuclear ... Dec. title A novel nuclear receptor corepressor complex, N CoR, contains components of the mammalian ... and activating signal cointegrator 2 as transcriptional coregulators of the orphan nuclear receptor .... title Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3 independent ... J Don year 2003 month Feb. title Regulation of androgen receptor activity by the nuclear receptor ... repression and nuclear receptor signaling journal PNAS Proc. Natl. Acad. Sci. U.S.A. volume ... nuclear receptor repression and activation journal Genes Dev. volume 15 issue 9 pages 1140 ... links MeshName nuclear receptor corepressor 2 3 nuclear receptor corepressor 2 NURSA C98 Further reading ... al. title Ligand independent repression by the thyroid hormone receptor mediated by a nuclear receptor ... RL, et al. title Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms ... P, Downes M, Xie W, et al. title Unique forms of human and mouse nuclear receptor corepressor SMRT ... to the nuclear receptor corepressor. journal Proc. Natl. Acad. Sci. U.S.A. volume 96 issue 7 pages ... P, et al. title The nuclear receptor corepressor N CoR regulates differentiation N CoR directly interacts ...   more details



  1. Photoreceptor cell-specific nuclear receptor

    PBB geneid 10002 The photoreceptor cell specific nuclear receptor PNR , also known as NR2E3 nuclear receptor subfamily 2, group E, member 3 , is a protein that in humans is encoded by the NR2E3 gene . ref name pmid10220376 cite journal author Kobayashi M, Takezawa S, Hara K, Yu RT, Umesono Y, Agata K, Taniwaki M, Yasuda K, Umesono K title Identification of a photoreceptor cell specific nuclear receptor journal Proc. Natl. Acad. Sci. U.S.A. volume 96 issue 9 pages 4814 9 year 1999 pmid 10220376 doi 10.1073 pnas.96.9.4814 pmc 21774 ref PNR is a member of the nuclear receptor super family of intracellular ... AF, Stone EM, Sheffield VC, Jacobson SG title The nuclear receptor NR2E3 plays a role in human retinal ... J, Ferraz F, Yu Umesono R, Munnich A, Kaplan J title The photoreceptor cell specific nuclear receptor ... author Chen F, Figueroa DJ, Marmorstein AD, et al. title Retina specific nuclear receptor A potential ... AV, et al. title Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome ... author Gerber S, Rozet JM, Takezawa SI, et al. title The photoreceptor cell specific nuclear receptor ... al. title Photoreceptor specific nuclear receptor NR2E3 functions as a transcriptional activator ... of photoreceptor specific nuclear receptor NR2E3 in rod photoreceptors of fetal human retina ... J title The rod photoreceptor specific nuclear receptor Nr2e3 represses transcription of multiple ... specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription ... of the orphan nuclear receptor NR2E3 causes autosomal dominant retinitis pigmentosa. journal Am. J ... R, Bennett J, Weleber RG, Fishman GA, Wright AF, Stone EM, Sheffield VC title Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate journal Nat. Genet ... doi 10.1093 hmg 10.16.1619 cite journal author Milam AH, Rose L, Cideciyan AV, et al. title The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration. journal ...   more details



  1. Nuclear receptor co-repressor 1

    PBB geneid 9611 The nuclear receptor co repressor 1 gene NCOR1 is a transcriptional coregulatory protein which contains several nuclear receptor interacting domains. In addition, NCOR1 appears to recruit histone deacetylase s to DNA promoter regions. Hence NCOR1 assists nuclear receptors in the down ... independent repression by the thyroid hormone receptor mediated by a nuclear receptor co repressor ... hormone and retinoic acid receptor associated co repressor 1 TRAC 1 . External links MeshName nuclear receptor corepressor 1 3 nuclear receptor corepressor 1 NURSA C97 Interactions Nuclear receptor ... 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification ... V J, Nevrivy D J, Leid M year 1999 month May. title Identification of nuclear receptor corepressor ... Zhang J, Miska E A, Guenther M G, Kouzarides T, Lazar M A year 2000 month Jan. title Nuclear receptor ... Qutob M S, Yee S P, Torchia J year 2000 month Dec. title A novel nuclear receptor corepressor complex ... Inhibition of the dihydrotestosterone activated androgen receptor by nuclear receptor corepressor ... P, Hollenberg Anthony N year 2005 month Feb. title The androgen receptor recruits nuclear receptor ... W H, Kumar R, Jameson J L year 1998 month Dec. title The interaction of the vitamin D receptor with nuclear ... T, et al. title Ligand independent repression by the thyroid hormone receptor mediated by a nuclear ... and characterization of a corepressor and potential component of the nuclear hormone receptor repression ... sensitivities of nuclear receptor corepressor binding to PML and PLZF RARalpha underlie molecular ... Unique forms of human and mouse nuclear receptor corepressor SMRT. journal Proc. Natl. Acad. Sci ... cite journal author Dowell P, Ishmael JE, Avram D, et al. title Identification of nuclear receptor ... Nagaya T, Chen KS, Fujieda M, et al. title Localization of the human nuclear receptor corepressor ... laysource laydate quote doi 10.1016 S0092 8674 02 00809 7 ref Glucocorticoid receptor , ref name pmid12569182 ...   more details



  1. Nuclear receptor related 1 protein

    PBB geneid 4929 The Nuclear receptor related 1 protein NURR1 also known as NR4A2 nuclear receptor subfamily 4, group A, member 2 is a protein that in humans is encoded by the NR4A2 gene . ref name pmid7706727 cite journal author Okabe T, Takayanagi R, Imasaki K, Haji M, Nawata H, Watanabe T title cDNA cloning of a NGFI B nur77 related transcription factor from an apoptotic human T cell line journal J. Immunol. volume 154 issue 8 pages 3871 9 year 1995 pmid 7706727 doi issn url http www.jimmunol.org cgi content abstract 154 8 3871 ref NURR1 is a member of the nuclear receptor family of intracellular ... nuclear receptor NURR1 journal Nucleic Acids Res. volume 34 issue 19 pages 5515 27 year 2006 pmid .... ref name entrez cite web title Entrez Gene NR4A2 nuclear receptor subfamily 4, group A, member ... had limited results. Interactions Nuclear receptor related 1 protein has been shown to Protein protein interaction interact with Retinoic acid receptor alpha ref name pmid7705655 cite journal author ... H title Organization of the human orphan nuclear receptor Nurr1 gene. journal Gene volume 230 issue ... of the retinoid X receptor beta, nuclear related receptor 1, and peroxisome proliferator activated receptor alpha genes in schizophrenia and alcohol dependence possible haplotype association of nuclear related receptor 1 gene to alcohol dependence. journal Am. J. Med. Genet. volume 114 issue 1 ..., Ponnio T, et al. title Activation of nuclear orphan receptor NURR1 transcription by NF kappa B and cyclic ... cite journal author Kim KS, Kim CH, Hwang DY, et al. title Orphan nuclear receptor Nurr1 directly transactivates ... refend External links MeshName Nurr1 nuclear receptor PDB Gallery geneid 4929 Transcription ... 7705655 doi 10.1101 gad.9.7.769 url issn ref Retinoic acid receptor beta . ref name pmid7705655 ... among nuclear hormone receptors. journal Cell volume 81 issue 4 pages 541 50 year 1995 pmid 7758108 ... immediate early response gene closely related to the steroid thyroid hormone receptor NAK1 ...   more details



  1. Translocator protein

    PBB geneid 706 Translocator protein TSPO is an 18 kDa protein of the outer mitochondrial membrane . It was first described as peripheral benzodiazepine receptor PBR , a secondary binding site for diazepam , but subsequent research has found the receptor to be expressed throughout the body and brain. ref ... JJ, Lindemann P, Norenberg MD, Nutt D, Weizman A, Zhang MR, Gavish M title Translocator protein 18kDa new nomenclature for the peripheral type benzodiazepine receptor based on its structure and molecular ... pmid 16822554 doi 10.1016 j.tips.2006.06.005 url issn ref In humans, the translocator protein is encoded ... receptor regional mapping of the gene and characterization of the receptor expressed from cDNA journal ... peripheral type benzodiazepine receptor journal Eur. J. Biochem. volume 195 issue 2 pages 305 11 year ... K title Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis journal ... R title A mitochondrial protein homologous to the mammalian peripheral type benzodiazepine receptor ... DC title Multiple forms and locations for the peripheral type benzodiazepine receptor journal Biochemical ... title Benzodiazepine Receptor Agonists Modulate Thymocyte Apoptosis Through Reduction of the Mitochondrial ... journal author Chen MK, Guilarte TR title Translocator protein 18 kDa TSPO molecular sensor of brain ... of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed ... author Veenman L, Papadopoulos V, Gavish M title Channel like functions of the 18 kDa translocator ... induced by translocator protein 18 kDa TSPO PBR ligands journal Neuropharmacology volume 53 issue 2 ... 3 ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis journal ... F, Da Pozzo E, Chelli B, Martini C title Translocator Protein Ligands as Promising Therapeutic Tools ... A, Kiese B, Schumacher M, Landgraf R, Holsboer F, Kucher K title Translocator Protein 18 kD as Target ... been used in receptor autoradiography to study neuroinflammation following brain injury. Selective Ligands ...   more details



  1. Aryl radical

    An Aryl radical in organic chemistry is an reactive intermediate and an arene compound incorporating one free radical carbon atom as part of the ring structure. As such it is the radical counterpart of the Arenium ion . The parent compound is the phenyl radical C sub 6 sub H sub 5 sub sup . sup ref Minireview Intermolecular Olefin Functionalisation Involving Aryl Radicals Generated from Arenediazonium Salts Markus R. Heinrich DOI 10.1002 chem.200801306 Chemistry A European Journal 2008 Volume 15 Issue 4, Pages 820 833 ref . Aryl radicals are intermediates in certain organic reaction s. Synthesis Aryl radicals can be obtained via aryl diazonium salt s. Alternatives for these salts are certain aryl triazene s and aryl hydrazine s. Aryl bromides and iodides can be converted to aryl radicals via tributyltin hydride and related compounds and silyl hydride s. Aryl halides can also be converted via electrosynthesis electrochemical cathodic reduction The mushroom Stephanospora caroticolor is suspected to generate an aryl radical as part of its biological chemical defence mechanism. Spectroscopy The parent phenyl radical has been identified via electron paramagnetic resonance and UV spectroscopy . Reactions Aryl radicals are very reactive and are found in many different reactions. Proton abstraction is considered a side reaction . Several reactions of synthetic utility in which aryl radicals feature are Halogen transfer reaction with electron deficient alkenes in the meerwein arylation biaryl coupling reaction couplings Sandmeyer reaction s addition to iminium ion s addition to sulfur dioxide References Reflist DEFAULTSORT Aryl Radical Category Reactive intermediates Category Free radicals ...   more details



  1. Aryl-acylamidase

    enzyme Name aryl acylamidase EC number 3.5.1.13 CAS number 9025 18 7 IUBMB EC number 3 5 1 13 GO code 0047680 image width caption In enzymology , an aryl acylamidase EC number 3.5.1.13 is an enzyme that catalysis catalyzes the chemical reaction an anilide H sub 2 sub O math rightleftharpoons math a carboxylate aniline Thus, the two substrate biochemistry substrates of this enzyme are anilide and water H sub 2 sub O , whereas its two product chemistry products are carboxylate and aniline . This enzyme belongs to the family of hydrolase s, those acting on carbon nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is aryl acylamide amidohydrolase . Other names in common use include AAA 1 , AAA 2 , brain acetylcholinesterase is associated with AAA 2 , and pseudocholinesterase associated with arylacylamidase . References reflist 1 cite journal author Nimmo Smith RH date 1960 title Aromatic N deacylation by chick kidney mitochondria journal Biochem. J. volume 75 pages 284&ndash 293 pmid 14427286 hydrolase stub Category EC 3.5.1 Category Enzymes of unknown structure Wickedpedia article ...   more details



  1. Aryl sulfotransferase

    enzyme Name aryl sulfotransferase EC number 2.8.2.1 CAS number 9026 09 9 IUBMB EC number 2 8 2 1 GO code 0004062 image width caption Pfam box Symbol Arylsulphotransferase Name Arylsulphotransferase Pfam PF05935 InterPro IPR010262 PROSITE PDB An aryl sulfotransferase EC number 2.8.2.1 is an enzyme that transfers a sulphat e group from phenol phenolic sulphate ester s to a phenolic acceptor substrate ref name PUB00011921 cite journal author Kim SK, Baek MC, Kim DH, Kim BK, Choi EC title Cloning and sequencing of the Klebsiella K 36 astA gene, encoding an arylsulfate sulfotransferase journal Microbiol. Immunol. volume 40 issue 8 pages 531 537 year 1996 pmid 8887346 ref . 3 phosphoadenylyl sulfate a phenol math rightleftharpoons math adenosine 3 ,5 bisphosphate an aryl sulfate Thus, the two substrate biochemistry substrates of this enzyme are 3 phosphoadenylyl sulfate and phenol , whereas its two product chemistry products are adenosine 3 ,5 bisphosphate and aryl sulfate . These enzymes are transferase s, specifically the sulfotransferase s, which transfer sulfur containing groups. The systematic name of this enzyme class is 3 phosphoadenylyl sulfate phenol sulfotransferase . Other names in common use include phenol sulfotransferase , sulfokinase , 1 naphthol phenol sulfotransferase , 2 naphtholsulfotransferase , 4 nitrocatechol sulfokinase , arylsulfotransferase , dopamine sulfotransferase , p nitrophenol sulfotransferase , phenol sulfokinase , ritodrine sulfotransferase , and PST . This enzyme participates in sulfur metabolism . Structural studies As of late 2007, 5 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1LS6 , PDB link 1Z28 , PDB link 1Z29 , PDB link 2A3R , and PDB link 2D06 . References reflist 1 Further reading refbegin cite journal author Romain Y, Demassieux S, Carriere S year 1982 title Partial purification and characterization of two isoenzymes involved in the sulfurylation of catecholamines ...   more details



  1. Hydrocarbon mixtures

    Unreferenced date December 2009 Orphan date October 2006 Hydrocarbon mixtures are a group of various Volatility chemistry volatile , highly flammable , mixtures used chiefly as nonpolar solvents . Composition Hydrocarbon mixtures are composed of hydrocarbon s, benzine , and petroleum ether s. A hydrocarbon is any chemical compound that consists only of the chemical element element s carbon C and hydrogen H . They all contain a carbon frame, and have hydrogen atoms attached to the frame. Often the term is used as a shortened form of the term aliphatic hydrocarbon . Most hydrocarbons are combustible . Benzine , also known as petroleum ether , is a hydrocarbon mixture. Benzine should not be confused with benzene . Benzine is a mixture of alkanes , such as pentane , hexane , and heptane . Benzene is a cyclic, aromatic hydrocarbon . Petroleum ether is obtained from petroleum refineries as the portion of the distillate which is intermediate between the lighter naphtha and the heavier kerosene . It has a specific gravity of between 0.6 and 0.8 depending on its composition. Petroleum ether should not be confused with the class of organic compounds called ethers . DEFAULTSORT Hydrocarbon Mixtures Category Alkanes Category Hydrocarbon solvents ...   more details



  1. Hydrocarbon economy

    Hydrocarbon economy is a term stressing that in the current world economy the world energy resources and consumption energy used mostly comes from three hydrocarbon s petroleum , coal , and natural gas . Hydrocarbon economy is often used when talking about possible alternatives like the hydrogen economy . ref http scholar.google.com scholar?q 22hydrocarbon economy 22&hl en&lr &start 30&sa N ref ref http www.google.com search?tab sw&sa N&q 22hydrocarbon economy 22&hl en&lr &sa N ref References reflist Category Energy economics Category Economies ...   more details



  1. Hydrocarbon keratosis

    A hydrocarbon keratosis also known as Pitch keratosis, Tar keratosis, and Tar wart is a Precancerous condition precancerous Keratosis keratotic skin lesion that occurs in people who have been occupationally exposed to polycyclic aromatic hydrocarbon s. ref name Fitz2 Freedberg, et. al. 2003 . Fitzpatrick s Dermatology in General Medicine . 6th ed. . McGraw Hill. ISBN 0071380760. ref rp 728 References reflist Diseases of the skin and subcutaneous tissue Category Dermatologic terminology Category Epidermal nevi, neoplasms, cysts Epidermal growth stub ...   more details



  1. Unsaturated hydrocarbon

    Unreferenced date December 2009 Unsaturated hydrocarbon s are hydrocarbon s that have double or triple covalent bond s between adjacent carbon atom s. Those with at least one double bond are called alkene s and those with at least one triple bond are called alkyne s. Each double bond is represented by a number preceding the name of the base chain, representing on which hydrocarbon in the chain the double or triple bond can be found. Alkenes and Alkynes with more than one double or triple bond respectively are named with the appropriate numeric prefix preceding the ene or yne. Ex. 2,4 pentadiene or 2 butyne Unsaturated hydrocarbons with both double and triple bonds have the suffix enyne and are handled in a similar manner. The physical properties of unsaturated hydrocarbons are very similar to those of the corresponding saturated compounds. They are slightly soluble in water. Except for aromatic compounds, unsaturated hydrocarbons are highly reactive and undergo addition reaction s to their multiple bonds. Typical reagents added are hydrogen halide s, water , sulfuric acid , elemental halogen s and alcohol s. Testing To test whether the hydrocarbon is unsaturated you should add bromine water. If the bromine water becomes decolourised Goes colorless then it is unsaturated. See also saturated hydrocarbon DEFAULTSORT Unsaturated Hydrocarbon Category Organic chemistry ar es Hidrocarburo insaturado hi lv Nepies tin tie og de ra i ja pl W glowodory nienasycone pt Hidrocarboneto insaturado ru zh ...   more details



  1. Unburned hydrocarbon

    Unreferenced date December 2009 Unburned hydrocarbons UHCs are the hydrocarbon s emitted after petroleum is burned in an engine. Any fuel entering a flame will be reacted. Dubious Running rich date July 2010 Thus, when unburned fuel is emitted from a combustor , the emission is caused by fuel avoiding the flame zones. For example, in piston engines, some of the fuel air mixture hides from the flame in the crevices provided by the piston ring grooves. Further, some regions of the combustion chamber may have a very weak flame, that is, they have either very fuel lean or very fuel rich conditions and consequently they have a low combustion temperature. These regions will cause intermediate species such as formaldehyde and alkene s to be emitted. Sometimes the term products of incomplete combustion, or PICs, is used to describe such species. DEFAULTSORT Unburned Hydrocarbon Category Fossil fuels Category Hydrocarbons ...   more details



  1. Hydrocarbon plant

    Hydrocarbon plants or petroleum plants are plants which produce terpenoid s as secondary metabolite s in sufficient quantities to make it economically feasible to convert their dry mass to gasoline like fuels. Nobel laureate Melvin Calvin has studied the terpenoid terpene biosynthetic pathway s of a number of species of plants to study and quantify this property in various species. Species include latex producing members of the Euphorbiaceae family that cannot be tapped for their liquid latex such as Euphorbia lathyris and Euphorbia tirucalli E. tirucalli . ref name Kalita2008 cite journal last1 Kalita first1 D title Hydrocarbon plant New source of energy for future journal Renewable and Sustainable Energy Reviews volume 12 issue 2 year 2008 pages 455 471 issn 13640321 doi 10.1016 j.rser.2006.07.008 ref ref name Ramawat2010 cite book author K. G. Ramawat title Desert Plants Biology and Biotechnology url http books.google.com books?id UNaNWN4zkqQC&pg PA37 accessdate 23 August 2010 year 2010 publisher Springer isbn 9783642025495 pages 37 ref See also Biogasoline Energy crop Asclepias References reflist bioenergy Category Biofuels material stub ...   more details



  1. Platonic hydrocarbon

    Platonic hydrocarbons are the molecule molecular representation of platonic solid geometries with vertices replaced by carbon atom s and with edges replaced by chemical bond s. Not all platonic solids have an organic molecular counterpart Tetravalent carbon excludes an icosahedron since 5 edges meet at each vertex Angle strain prevents formation of an octahedron , ref Nevertheless, note the existence of 1.1.1.1 paddlane C CH sub 2 sub sub 4 sub C, CAS number CAS 102843 69 6 and the theoretical existence of pyramidane which is a half octahedron with one carbon on a vertex like those of octahedron. ref and since 4 edges meet at each corner, there would be no hydrogen atoms, thus this hypothetical octahedron molecule would be an allotrope C sub 6 sub of elemental carbon, not a hydrocarbon. The following platonic hydrocarbons, on the other hand, have been chemical synthesis synthesised Cubane C sub 8 sub H sub 8 sub Dodecahedrane C sub 20 sub H sub 20 sub . Tetrahedrane C sub 4 sub H sub 4 sub has not yet been synthesized, but it is predicted to be kinetically stable in spite of the acute bond angle and consequent angle strain. Tetrahedral hydrocarbons, including tetrahedrane with tert butyl substituents and with trimethylsilyl substituents have been produced. With increasing number of carbon atoms in the frame, the geometry more closely approximates a sphere, and the space enclosed in the carbon cage increases. This trend continues with buckyballs or spherical fullerene C sub 60 sub . Although not a hydrocarbon, fullerene has the shape of a truncated icosahedron , an Archimedean solid . gallery Image Tetrahedrane 3D balls.png Tetrahedrane Image Cubane 3D balls.png Cubane Image Dodecahedrane 3D balls.png Dodecahedrane gallery Notes references References Henning Hopf, Classics in Hydrocarbon Chemistry , Wiley VCH, 2000. commonscat platonic hydrocarbons Category Hydrocarbons Category Platonic solids Hydrocarbons de Platonische Kohlenwasserstoffe es Hidrocarburo plat nico ...   more details




Articles 1 - 25 of 50952          Next


Search   in  
Search for Aryl hydrocarbon receptor nuclear translocator in Tutorials
Search for Aryl hydrocarbon receptor nuclear translocator in Encyclopedia
Search for Aryl hydrocarbon receptor nuclear translocator in Videos
Search for Aryl hydrocarbon receptor nuclear translocator in Books
Search for Aryl hydrocarbon receptor nuclear translocator in Software
Search for Aryl hydrocarbon receptor nuclear translocator in DVDs
Search for Aryl hydrocarbon receptor nuclear translocator in Store


Advertisement




Aryl hydrocarbon receptor nuclear translocator in Encyclopedia
Aryl hydrocarbon receptor nuclear translocator top Aryl hydrocarbon receptor nuclear translocator
Home - Add TutorGig to Your Site - Disclaimer

©2011-2013 TutorGig.com. All Rights Reserved. Privacy Statement