Apoptosome
The apoptosome is a large ternary protein structure formed in the process of apoptosis . Its formation ... binds to apaf 1, however its exact role is still debated. The formation, the apoptosome, had never ..
Apaf-1
from the mitochondria , it interacts with Apaf 1 and dATP to form the apoptosome , a large oligomeric ... of 2006 from the laboratory of Guy Salvesen suggests that the apoptosome may induce caspase 9 ..
Guy Salvesen
Pop C, Timmer J, Sperandio S, Salvesen GS. 2006 The apoptosome activates caspase 9 by dimerization ..
APAF1
forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing ... Y, Liu X, Wang X title An APAF 1.cytochrome c multimeric complex is a functional apoptosome that activates ..
Caspase
the apoptosome regulated by cytochrome c and the bcl 2 Bcl 2 family which activates caspase 9 . Some ... and skeletal muscle myoblasts, See also Apoptosis pyroptosis Bcl 2 Apoptosome paracaspase metacaspase ..
Bcl-2-associated X protein
insertion into the mitochondrial membrane. See also Apoptosis Apoptosome Bcl 2 BH3 interacting domain ..
Biological immortality
journal title Predominant suppression of apoptosome by inhibitor of apoptosis protein in non small ..
Noxa
has been shown to be involved in p53 mediated apoptosis. See also Apoptosis Apoptosome Bcl 2 ..
Caspase-9
and activation of apaf 1 apoptosome , which in turn cleaves the pro enzyme of caspase 9 into the active ..
NOD1
cite journal author Chu ZL, Pio F, Xie Z, et al. title A novel enhancer of the Apaf1 apoptosome involved ..
NLRP1
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c dependent caspase activation and apoptosis ..
Apoptosis
to create a protein complex known as an apoptosome . The apoptosome cleaves the pro caspase to its active ... S, et al title Predominant suppression of apoptosome by inhibitor of apoptosis protein in non small ..
Bcl-2
malignancies , Blood. 106 2 408 418 2005 . PMID 15797997 ref . See also Apoptosis Apoptosome ..
Deleted in Colorectal Cancer
of caspase 3 through caspase 9, and initiates apoptosis without the formation of an apoptosome or cytochrome ... that is apoptosome independent. ref name Arakawa To put this into a biological systems ..
Autophagy network
. Induction of non apoptotic ce...PMID 17094451 Moreno S et al. Apoptosome impairment during ...PMID ..