Instruction may refer to:

• Education, the teaching and learning of knowledge
• Teaching, a form of instruction
• Sebayt, a work of the ancient Egyptian didactic literature aiming to teach ethical behaviour
• Instruction (band), a rock band from New York City
• Instruction (computer science), a single operation of a processor within a computer architecture
• Instructions (album), by Jermaine Dupri
• Instruction, in inquisitorial systems of justice, the pre-trial phase of an investigation led by a judge

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