XX male syndrome (also called de la Chapelle syndrome) is a rare sex chromosomal disorder. Usually it is caused by unequal crossing over between X and Y chromosomes during meiosis. Symptoms include small testes, gynecomastia and sterility. Many individuals with this condition also have effeminate characteristics.

Men typically have one X chromosome and one Y chromosome in each diploid cell of their bodies. Women typically have two X chromosomes. So-called XX males have two X chromosomes; thus they are genetically female but otherwise appear to be male.

See also

• Swyer syndrome
• X chromosome, for other diseases related to the X chromosome.

References

External links

fr:Syndrome Homme XX sv:Manlig pseudohermafroditism