Uncle may refer to:

• A family relationship, either the brother of a parent or the husband of a sister of a parent. A woman with an equivalent relationship is an aunt, and the reciprocal relationship is that of a nephew or niece. See Cousin.

• A title of respect for elders (for example neighbours, acquaintances, as well as total strangers), especially in Nigeria, India, Pakistan, Turkey, China, Maori culture and most Pacific Islands

• An honorific bestowed upon individuals of any gender. See fictive kinship.

• A cry of surrender or safeword

An idiom:

• Dutch uncle, a person who delivers stern lectures
• Uncle Sam, a personification of the United States
• Uncle Tom, a pejorative term for a black person who plays up to racial stereotypes
• Uncle Tom Cobley, a British folk saying meaning "etcetera"
• Bob's your uncle, a Commonwealth expression roughly equivalent to "and there you have it"

A person:

• Blind Uncle Gaspard
• Uncle Charlie Osborne, a musician from the Appalachian Mountains
• Uncle Dave Macon, American musician
• Uncle Fester (author), the penname of Steve Preisler
• Uncle Ho, a nickname for the Vietnamese leader Ho Chi Minh
• Uncle Joe, a nickname for the Soviet leader Joseph Stalin
• Uncle Kracker, American musician
• Uncle Miltie, a nickname for Milton Berle
• Royal Uncle Cao, a Chinese deity
• Uncle Tupelo, American music
• Uncle Patrick, NBA Hall of Famer Patrick Ewing

A book:

• My Uncle Oswald, an adult novel written by Roald Dahl
• Uncle, a series of children's books
• Uncle Dynamite, a book by P. G. Wodehouse
• Uncle John's Bathroom Reader
• Uncle Tom's Cabin, a novel about slavery by Harriet Beecher Stowe
• Uncle Tungsten: Memories of a Chemical Boyhood, a memoir by Oliver Sacks
• Uncle Vanya, a play by Anton Chekhov
• Uncle Wiggily, a series of children's books

A fictional character:

• Uncle Albert, a character in the sitcom Only Fools and Horses
• Uncle Ben, a character in the Spider-Man comic book
• Uncle Creepy, a character in the Creepy horror-comics magazine
• Uncle Duke, a character in the comic strip Doonesbury
• Uncle Fester, a character in the sitcom The Addams Family
• Uncle Fred, a character in the short stories and novels of P. G. Wodehouse
• Uncle Henry (Oz), a character in the book The Wonderful Wizard of Oz
• Uncle Iroh from the animated television series Avatar: The Last Airbender
• Uncle Jesse, one of several characters
• Rich Uncle Pennybags, the mascot of the Monopoly game
• Uncle Remus, the fictional narrator of a collection of African American folktales
• Uncle Ruckus, self-hating African American white supremacist from the comic strip and animated televisions series The Boondocks
• Uncle Scrooge, the main character in the Scrooge McDuck comic books
• Uncle Chan from Jackie Chan Adventures

A film or television show:

• The Man from U.N.C.L.E., a television show
  • The Girl from U.N.C.L.E., a spinoff show
  • U.N.C.L.E., the agency in these shows
• The Uncle Floyd Show
• The Monkey's Uncle, a 1965 Disney film
• My Uncle Benjamin, a 1969 French film
• My American Uncle, a 1980 French film
• Uncle Buck, a 1989 comedy film
• Uncle Nino, a 2003 family film
• "Uncle Simon" (The Twilight Zone), episode

A piece of music:

• Kill Uncle, a 1991 album by Morrissey
• "Third Uncle" a 1974 song by Brian Eno
• Uncle Anesthesia an album by Screaming Trees|the Screaming Trees
• Uncle Meat, a 1969 soundtrack by Frank Zappa
• "Uncle Fucka" a vulgar song from South Park: Bigger, Longer & Uncut
• "Uncle Pat", a single by Ash

A food product:

• Uncle Ben's, a brand of packaged food products
• Uncle Joe's Mint Balls, a candy
• Uncle Arthur, Guinness stout, a reference to the founder, Arthur Guinness

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