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Trace amine-associated receptor
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Trace amine-associated receptor

Trace amine-associated receptors, abbreviated TAAR and previously abbreviated TAR and TA, are a class of G protein-coupled receptors identified in 2001.[1]

These receptors have gained considerable interest in academic and pharmaceutical industry research as putative endogenous receptors for trace amines, metabolic derivatives of classical biogenic amines.[2][3][4]

In 2006 it was shown that TAAR1 is most probably a receptor for thyronamines, decarboxylated and deiodinated metabolites of the thyroid hormones, while the mouse mTAAR2 - mTAAR9 receptors are most probably olfactory receptors for volatile amines.[5]

Contents


Mammalian TAAR complement

See also

External links

References





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