Trace amine-associated receptor
Trace amine-associated receptors , abbreviated TAAR and previously abbreviated TAR and TA , are a class of G protein-coupled receptors identified in 2001.[1]
These receptors have gained considerable interest in academic and pharmaceutical industry research as putative endogenous receptors for trace amines , metabolic derivatives of classical biogenic amines .[2] [3] [4]
In 2006 it was shown that TAAR1 is most probably a receptor for thyronamines , decarboxylated and deiodinated metabolites of the thyroid hormones , while the mouse mTAAR2 - mTAAR9 receptors are most probably olfactory receptors for volatile amines .[5]
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