Tolosa may refer to:

• Tolosa is the Latin and Occitan name for the town of Toulouse, France
• Tolosa, Leyte, a municipality in the Philippines
• Tolosa, Spain is also a locality in Guipúzcoa, Spain
• Tolosa, Portugal is also a locality in Nisa, Portugal.
• Tolosa, Buenos Aires is also a locality in La Plata Partido, Argentina, founded by Martín J. Iraola, born in the Guipuzcoan Tolosa.
• Tolosa is also a 5450 m high peak next to Aconcagua, in Andes.
• 138 Tolosa is an asteroid.
• Tolosa, Jose Benjamin is an Actor born on October 9th, 1978 in Argentina, also an American resident since 2004.
• Tolosa-Hunt syndrome, a rare medical disorder.

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