Thiouracil refers both to a specific molecule consisting of a sulfated uracil, and a family of molecules based upon that structure. The substance is a historically relevant antithyroid preparation; Astwood E.B. used it in 1943 as therapy of the Graves' disease for the first time. ^[1]

Reference

1. ↑ Gerabek W.: Enzyklopädie Medizingeschichte, S 152, 2005