A large-sized note is a bill of any denomination of U.S. currency printed between 1863 and 1929. This is in contrast with small-sized notes, which were printed starting in 1928. Large-sized notes exist in denominations of $1 through $10000. The most common large-sized notes are the Federal Reserve Notes of Series 1914 and 1918. These are detailed below, but are only a subset of all large-sized notes made by the Bureau of Engraving and Printing (BEP).

Denominations for Series 1914/1918

Denomination	Portrait	Nickname	Design on back
$5	Abraham Lincoln	Fin	Arrival of the Pilgrims
$10	Andrew Jackson	Sawbuck	Farming with horses (left), American Industry (right)
$20	Grover Cleveland	Double sawbuck	Steam locomotive, Steamship
$50	Ulysses S Grant	Half C-note	Panama (center) and 2 Steam Ships
$100	Benjamin Franklin	C-note	Farmer with Wheat (left), The Roman god Mercury with package (right), Three women with cornucopia (center)
$500	John Marshall		American Revolutionary War
$1000	Alexander Hamilton		Bald Eagle
$5000	James Madison		George Washington receiving his Commission
$10,000	Salmon P. Chase		Embarkation of the Pilgrims

According to the BEP, the small-sized notes measure 2.61 by 6.14 by 0.0043 inches. Large-sized notes were 3.125 by 7.4218 inches.

A large-sized note can also refer to a large-denomination banknote in various currencies.