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Random chimeragenesis on transient templates

Random chimeragenesis on transient templates (RACHITT) is a method to perform molecular mutagenesis at a high recombination rate. DNA shuffling is a similar but less powerful method used in directed evolution experiments.

References

  • Coco, W.M. et al. Nat. Biotechnol. 19, 354?359 (2001).





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