Publius Mucius Scaevola (? c. 115 BC) was a prominent Roman politician and jurist. He was tribune in 141 BC, praetor in 136 BC, and consul in 133 BC.

During his consulship, Publius Cornelius Scipio Nasica Serapio opposed Tiberius Gracchus running for a second consecutive tribuneship. Mucius said that he would allow Gracchus to run since that seemed to be the wishes of the people and he did not want to resort to violence to prevent him from running. Scipio though continued to protest and led the mob that killed Gracchus. Mucius did not condemn Scipio for these actions despite his earlier comments.

He later became Pontifex Maximus in 131 BC after the death of his brother, Publius Licinius Crassus Dives Mucianus. He is the last Pontifex Maximus to have published the Annales Maximi, the list of events of the year.

ca:Publi Muci Escevola (jurista) de:Publius Mucius Scaevola fr:Publius Mucius Scævola (consul en -133) es:Publio Mucio Escévola it:Publio Muzio Scevola (console 133 a.C.)