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Protoporphyrin IX

In the metabolism of porphyrin, protoporphyrin IX is created by the enzyme protoporphyrinogen oxidase, and the enzyme ferrochelatase converts it into heme.

Heme synthesis - note that some reactions occur in the cytoplasm and some in the mitochondrion (yellow)
Heme synthesis - note that some reactions occur in the cytoplasm and some in the mitochondrion (yellow)





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