Nebuchadnezzar (or Nebuchadrezzar) was the name of several kings of Babylonia.

• Nebuchadnezzar I
• Nebuchadnezzar II, the best known of these kings (the one mentioned in the biblical Book of Daniel), who conquered Aram and Judah
• Nebuchadnezzar III (Niditu-bel), rebelled against Darius I of Persia (522 BC)
• Nebuchadnezzar IV (Arakha), also rebelled against Darius I of Persia (521 BC)

It may also refer to:

• Nebuchadnezzar (wine), an oversized champagne bottle, which holds 15 litres
• Nebuchadnezzar (The Matrix), the name of Morpheus' vessel in the science fiction films The Matrix and The Matrix Reloaded
• Nebuchadnezzar (spelled Nabuchodonosor (Nab) in the French original), the name of one of the characters in Jules Verne's novel The Mysterious Island
• Nebuchadnezzar (Neb), a character in Brian Jacques' Castaways of the Flying Dutchman

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