This is a list of notable people of possible Melungeon ancestry.

• Ava Gardner
• Tom Hanks
• Abraham Lincoln (via mother, Nancy Hanks)
• Steve Martin
• Elvis Presley

Some lesser-known noteworthy Melungeons:

• Vardemon Collins, Melungeon patriarch
• Brent Kennedy, author
• Jack Goins, author & archivist
• Rich Mullins, singer-songwriter
• Claude Collins, educator & activist
• DruAnna Overbay, author & educator
• Jimmy Martin, "The King of Bluegrass"
• Lisa Alther, novelist
• Wayne Winkler, author
• Mahala Mullins, famed moonshiner and folk heroine
• Harrison Collins, Medal of Honor recipient (Civil War)
• Jim Callahan, author
• Mattie Ruth Johnson, author
• Daisy M. Carthell Johnson, Past Worthy Grand Matron (Eastern Star)
• Chris Goins, lumber yard impresario