Hypoxia literally means "a deficiency in oxygen." It can refer to:
Hypoxia (medical), a shortage of oxygen in the body. Hypoxaemia is the reduction of oxygen specifically in the blood; anoxia is when there is no oxygen available at all.
Environmental hypobaric hypoxia, a condition at high altitudes such as mountains where the reduced partial pressure of oxygen results in hypoxia.
Ischemia, a restriction in blood supply (and therefore oxygen supply) to an organ or section of the body, generally due to constriction or blocking of blood vessels.
Hypoxia (environmental) or oxygen depletion, a reduced concentration of dissolved oxygen in a water body leading to stress and death in aquatic organisms.