In addition to her news anchoring duties, Rancic often co-hosts red carpet events for award shows, such as the Golden Globes and the Academy Awards. On March 13, 2006, she was joined as host of E! News by Ryan Seacrest. She is the creator and executive producer of MTV's Celebrity Rap Superstar, which premiered in 2007.
Giuliana was raised in the Washington, D.C. metropolitan area, she is a gradualte of Walt Whitman High School (Bethesda MD), received a bachelor's degree in Journalism from the University of Maryland, and a master's degree in Journalism from American University. Her father, Edoardo DePandi, is a master tailor. The DePandi family owns Bruno Cipriani, an expensive shoppe in White Flint Mall. She has a sister Monica and an opera singer brother Pasquale DePandi.