Fabrizio Colonna (c. 1450 – March 18, 1520) was an Italian condottiero, a member of the powerful Colonna family. He was the son of Edoardo Colonna and Filippa Conti.

Fabrizio was born sometime before 1452. He was married to Agnese da Montefeltro daughter of Federico da Montefeltro, 1st Duke of Urbino, and Battista Sforza. Fabrizio was known as count of Tagliacozzo and grand constable of the kingdom of Naples.

He was a general in the Holy League that fought against Louis XII of France.

His daughter was Vittoria Colonna, who was an Italian poet, and a close friend of Michelangelo. His nephew Marcantonio was also a successful general.

See also

• Vittoria Colonna
• Prospero Colonna
• Marcantonio Colonna
• Colonna family

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