Butternut has multiple meanings:

• Butternut squash, an edible winter squash.
• Butternut (tree), a type of walnut tree native to North America.
• Caryocar nuciferum, known as "butternut", a type of nut tree native to South America
• Butternut, a shade of the colour yellow associated with butternut squash
• Butternut, a regional brand of bread marketed by the Interstate Bakeries Corporation
• Butternuts, a nickname given to Confederate soldiers who wore butternut colored uniforms during the American Civil War; also a term referring to Northerners sympathetic to the South ("Copperheads").
• USS Butternut (YAG-60), a ship of the United States Navy.
• Butternut (Candy), a defunct brand of chocolate candy bars with caramel and peanuts, made by Hollywood Brands
• Butternut Coffee, a brand originally produced by the Paxton and Gallagher Wholesale Grocery, and later Swanson.

Butternut in geography:

• Butternut, Wisconsin, USA
• The Butternut State, Tennessee, USA
• Butternut Valley Township, Minnesota, USA
• Butternuts, New York, USA
• Ski Butternut, a ski resort in Great Barrington, Massachusetts, USA