The Twelve Apostles, 12 of Jesus' disciples chosen by him and given "the Great Commission"
The Seventy Disciples, referred to as Seventy Apostles by the Orthodox Church
Apostle (Latter Day Saints), a position within The Church of Jesus Christ of Latter-day Saints and other denominations of the Latter Day Saint movement
Chief Apostle, highest minister in the New Apostolic Church
Rasul, Islamic prophet or messenger, sometimes translated "apostle" (Muhammad is known as Ras?lull?h, "Apostle of God")
In art and entertainment:
The Apostle, a 1997 film directed by and starring Robert Duvall